1.
Cell Mol Neurobiol
; 32(3): 467-475, 2012 04.
Article
in English
| MEDLINE
| ID: mdl-22297541
ABSTRACT
Adeno-associated virus vector plasmid carrying the expression cassette of brain-derived neurotrophic factor (BDNF), pAAV-BDNF, was constructed and packaged into recombinant adeno-associated virus (rAAV-BDNF). The rAAV-BDNF was intravitreally injected into streptzotocin (STZ)-induced diabetic Sprague-Dawley (SD) Rats. Data showed that over-expression of BDNF could increase alive retinal ganglion cell (RGC) number and improve its function in streptzotocin(STZ)-induced diabetic rats, which might be a new method to treat diabetic neuropathy and retinopathy.
2.
Protein Cell
; 5(1): 4-7, 2014 Jan.
Article
in English
| MEDLINE
| ID: mdl-24492924