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1.

Exploiting Nanobodies' Singular Traits.

Ingram, Jessica R; Schmidt, Florian I; Ploegh, Hidde L.

Annu Rev Immunol ; 36: 695-715, 2018 04 26.

Article in English | MEDLINE | ID: mdl-29490163

2.

Mitochondrial damage activates the NLRP10 inflammasome.

Próchnicki, Tomasz; Vasconcelos, Matilde B; Robinson, Kim S; Mangan, Matthew S J; De Graaf, Dennis; Shkarina, Kateryna; Lovotti, Marta; Standke, Lena; Kaiser, Romina; Stahl, Rainer; Duthie, Fraser G; Rothe, Maximilian; Antonova, Kateryna; Jenster, Lea-Marie; Lau, Zhi Heng; Rösing, Sarah; Mirza, Nora; Gottschild, Clarissa; Wachten, Dagmar; Günther, Claudia; Kufer, Thomas A; Schmidt, Florian I; Zhong, Franklin L; Latz, Eicke.

Nat Immunol ; 24(4): 595-603, 2023 04.

Article in English | MEDLINE | ID: mdl-36941400

3.

Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19.

Krämer, Benjamin; Knoll, Rainer; Bonaguro, Lorenzo; ToVinh, Michael; Raabe, Jan; Astaburuaga-García, Rosario; Schulte-Schrepping, Jonas; Kaiser, Kim Melanie; Rieke, Gereon J; Bischoff, Jenny; Monin, Malte B; Hoffmeister, Christoph; Schlabe, Stefan; De Domenico, Elena; Reusch, Nico; Händler, Kristian; Reynolds, Gary; Blüthgen, Nils; Hack, Gudrun; Finnemann, Claudia; Nischalke, Hans D; Strassburg, Christian P; Stephenson, Emily; Su, Yapeng; Gardner, Louis; Yuan, Dan; Chen, Daniel; Goldman, Jason; Rosenstiel, Philipp; Schmidt, Susanne V; Latz, Eicke; Hrusovsky, Kevin; Ball, Andrew J; Johnson, Joe M; Koenig, Paul-Albert; Schmidt, Florian I; Haniffa, Muzlifah; Heath, James R; Kümmerer, Beate M; Keitel, Verena; Jensen, Björn; Stubbemann, Paula; Kurth, Florian; Sander, Leif E; Sawitzki, Birgit; Aschenbrenner, Anna C; Schultze, Joachim L; Nattermann, Jacob.

Immunity ; 54(11): 2650-2669.e14, 2021 11 09.

Article in English | MEDLINE | ID: mdl-34592166

4.

Brain endothelial GSDMD activation mediates inflammatory BBB breakdown.

Wei, Chao; Jiang, Wei; Wang, Ruiyu; Zhong, Haoyu; He, Huabin; Gao, Xinwei; Zhong, Shilin; Yu, Fengting; Guo, Qingchun; Zhang, Li; Schiffelers, Lisa D J; Zhou, Bin; Trepel, Martin; Schmidt, Florian I; Luo, Minmin; Shao, Feng.

Nature ; 629(8013): 893-900, 2024 May.

Article in English | MEDLINE | ID: mdl-38632402

5.

Jack of all trades inhibits inflammation (in sober people).

Schmidt, Florian I; Latz, Eicke.

Nat Immunol ; 21(7): 718-719, 2020 07.

Article in English | MEDLINE | ID: mdl-32577009

6.

CD14-New Tricks of an Old Acquaintance.

Schmidt, Florian I; Latz, Eicke.

Immunity ; 47(4): 606-608, 2017 10 17.

Article in English | MEDLINE | ID: mdl-29045891

7.

Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever.

Mangan, Matthew S J; Gorki, Friederike; Krause, Karoline; Heinz, Alexander; Pankow, Anne; Ebert, Thomas; Jahn, Dieter; Hiller, Karsten; Hornung, Veit; Maurer, Marcus; Schmidt, Florian I; Gerhard, Ralf; Latz, Eicke.

PLoS Biol ; 20(11): e3001351, 2022 11.

Article in English | MEDLINE | ID: mdl-36342970

8.

The endogenous cellular protease inhibitor SPINT2 controls SARS-CoV-2 viral infection and is associated to disease severity.

Ramirez Alvarez, Carlos; Kee, Carmon; Sharma, Ashwini Kumar; Thomas, Leonie; Schmidt, Florian I; Stanifer, Megan L; Boulant, Steeve; Herrmann, Carl.

PLoS Pathog ; 17(6): e1009687, 2021 06.

Article in English | MEDLINE | ID: mdl-34181691

9.

Recessive NLRC4-Autoinflammatory Disease Reveals an Ulcerative Colitis Locus.

Steiner, Annemarie; Reygaerts, Thomas; Pontillo, Alessandra; Ceccherini, Isabella; Moecking, Jonas; Moghaddas, Fiona; Davidson, Sophia; Caroli, Francesco; Grossi, Alice; Castro, Fabio Fernandes Morato; Kalil, Jorge; Gohr, Florian N; Schmidt, Florian I; Bartok, Eva; Zillinger, Thomas; Hartmann, Gunther; Geyer, Matthias; Gattorno, Marco; Mendonça, Leonardo Oliveira; Masters, Seth L.

J Clin Immunol ; 42(2): 325-335, 2022 02.

Article in English | MEDLINE | ID: mdl-34783940

10.

Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells.

Bosso, Matteo; Prelli Bozzo, Caterina; Hotter, Dominik; Volcic, Meta; Stürzel, Christina M; Rammelt, Annika; Ni, Yi; Urban, Stephan; Becker, Miriam; Schelhaas, Mario; Wittmann, Sabine; Christensen, Maria H; Schmidt, Florian I; Gramberg, Thomas; Sparrer, Konstantin M J; Sauter, Daniel; Kirchhoff, Frank.

PLoS Pathog ; 16(8): e1008752, 2020 08.

Article in English | MEDLINE | ID: mdl-32760121

11.

Autoinflammatory disease with corneal and mucosal dyskeratosis caused by a novel NLRP1 variant.

Herlin, Troels; Jørgensen, Sofie E; Høst, Christian; Mitchell, Patrick S; Christensen, Maria Hønholt; Laustsen, Mira; Larsen, Dorthe A; Schmidt, Florian I; Christiansen, Mette; Mogensen, Trine H.

Rheumatology (Oxford) ; 59(9): 2334-2339, 2020 09 01.

Article in English | MEDLINE | ID: mdl-31873740

12.

Localized CD47 blockade enhances immunotherapy for murine melanoma.

Ingram, Jessica R; Blomberg, Olga S; Sockolosky, Jonathan T; Ali, Lestat; Schmidt, Florian I; Pishesha, Novalia; Espinosa, Camilo; Dougan, Stephanie K; Garcia, K Christopher; Ploegh, Hidde L; Dougan, Michael.

Proc Natl Acad Sci U S A ; 114(38): 10184-10189, 2017 09 19.

Article in English | MEDLINE | ID: mdl-28874561

13.

From atoms to physiology: what it takes to really understand inflammasomes.

Schmidt, Florian I.

J Physiol ; 597(22): 5335-5348, 2019 11.

Article in English | MEDLINE | ID: mdl-31490557

14.

Spike D614G - A Candidate Vaccine Antigen Against Covid-19.

Koenig, Paul-Albert; Schmidt, Florian I.

N Engl J Med ; 384(24): 2349-2351, 2021 06 17.

Article in English | MEDLINE | ID: mdl-34133867

15.

Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication.

Hanke, Leo; Schmidt, Florian I; Knockenhauer, Kevin E; Morin, Benjamin; Whelan, Sean Pj; Schwartz, Thomas U; Ploegh, Hidde L.

EMBO Rep ; 18(6): 1027-1037, 2017 06.

Article in English | MEDLINE | ID: mdl-28396572

16.

Disruption of Sphingolipid Biosynthesis Blocks Phagocytosis of Candida albicans.

Tafesse, Fikadu G; Rashidfarrokhi, Ali; Schmidt, Florian I; Freinkman, Elizaveta; Dougan, Stephanie; Dougan, Michael; Esteban, Alexandre; Maruyama, Takeshi; Strijbis, Karin; Ploegh, Hidde L.

PLoS Pathog ; 11(10): e1005188, 2015 Oct.

Article in English | MEDLINE | ID: mdl-26431038

17.

Intracellular expression of camelid single-domain antibodies specific for influenza virus nucleoprotein uncovers distinct features of its nuclear localization.

Ashour, Joseph; Schmidt, Florian I; Hanke, Leo; Cragnolini, Juanjo; Cavallari, Marco; Altenburg, Arwen; Brewer, Rebeccah; Ingram, Jessica; Shoemaker, Charles; Ploegh, Hidde L.

J Virol ; 89(5): 2792-800, 2015 Mar.

Article in English | MEDLINE | ID: mdl-25540369

18.

The E2 ubiquitin-conjugating enzyme UBE2J1 is required for spermiogenesis in mice.

Koenig, Paul-Albert; Nicholls, Peter K; Schmidt, Florian I; Hagiwara, Masatoshi; Maruyama, Takeshi; Frydman, Galit H; Watson, Nicki; Page, David C; Ploegh, Hidde L.

J Biol Chem ; 289(50): 34490-502, 2014 Dec 12.

Article in English | MEDLINE | ID: mdl-25320092

19.

Single-virus fusion experiments reveal proton influx into vaccinia virions and hemifusion lag times.

Schmidt, Florian I; Kuhn, Phillip; Robinson, Tom; Mercer, Jason; Dittrich, Petra S.

Biophys J ; 105(2): 420-31, 2013 Jul 16.

Article in English | MEDLINE | ID: mdl-23870263

20.

Vaccinia virus strains use distinct forms of macropinocytosis for host-cell entry.

Mercer, Jason; Knébel, Stephan; Schmidt, Florian I; Crouse, Josh; Burkard, Christine; Helenius, Ari.

Proc Natl Acad Sci U S A ; 107(20): 9346-51, 2010 May 18.

Article in English | MEDLINE | ID: mdl-20439710

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