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1.
Anesth Analg ; 132(1): 38-45, 2021 01.
Article in English | MEDLINE | ID: mdl-33315602

ABSTRACT

BACKGROUND: Numerous barrier devices have recently been developed and rapidly deployed worldwide in an effort to protect health care workers (HCWs) from exposure to coronavirus disease 2019 (COVID-19) during high-risk procedures. However, only a few studies have examined their impact on the dispersion of droplets and aerosols, which are both thought to be significant contributors to the spread of COVID-19. METHODS: Two commonly used barrier devices, an intubation box and a clear plastic intubation sheet, were evaluated using a physiologically accurate cough simulator. Aerosols were modeled using a commercially available fog machine, and droplets were modeled with fluorescein dye. Both particles were propelled by the cough simulator in a simulated intubation environment. Data were captured by high-speed flash photography, and aerosol and droplet dispersion were assessed qualitatively with and without a barrier in place. RESULTS: Droplet contamination after a simulated cough was seemingly contained by both barrier devices. Simulated aerosol escaped the barriers and flowed toward the head of the bed. During barrier removal, simulated aerosol trapped underneath was released and propelled toward the HCW at the head of the bed. Usage of the intubation sheet concentrated droplets onto a smaller area. If no barrier was used, positioning the patient in slight reverse Trendelenburg directed aerosols away from the HCW located at the head of the bed. CONCLUSIONS: Our observations imply that intubation boxes and sheets may reduce HCW exposure to droplets, but they both may merely redirect aerosolized particles, potentially resulting in increased exposure to aerosols in certain circumstances. Aerosols may remain within the barrier device after a cough, and manipulation of the box may release them. Patients should be positioned to facilitate intubation, but slight reverse Trendelenburg may direct infectious aerosols away from the HCW. Novel barrier devices should be used with caution, and further validation studies are necessary.


Subject(s)
COVID-19/therapy , Infection Control/instrumentation , Infectious Disease Transmission, Patient-to-Professional/prevention & control , Inhalation Exposure/prevention & control , Intubation, Intratracheal , Occupational Exposure/prevention & control , Personal Protective Equipment , Aerosols , COVID-19/transmission , Humans , Inhalation Exposure/adverse effects , Intubation, Intratracheal/adverse effects , Manikins , Materials Testing , Occupational Exposure/adverse effects , Occupational Health
2.
Anesthesiology ; 133(4): 892-904, 2020 10 01.
Article in English | MEDLINE | ID: mdl-32639236

ABSTRACT

BACKGROUND: During the COVID-19 pandemic, ventilator sharing was suggested to increase availability of mechanical ventilation. The safety and feasibility of ventilator sharing is unknown. METHODS: A single ventilator in pressure control mode was used with flow control valves to simultaneously ventilate two patients with different lung compliances. The system was first evaluated using high-fidelity human patient simulator mannequins and then tested for 1 h in two pairs of COVID-19 patients with acute respiratory failure. Patients were matched on positive end-expiratory pressure, fractional inspired oxygen tension, and respiratory rate. Tidal volume and peak airway pressure (PMAX) were recorded from each patient using separate independent spirometers and arterial blood gas samples drawn at 0, 30, and 60 min. The authors assessed acid-base status, oxygenation, tidal volume, and PMAX for each patient. Stability was assessed by calculating the coefficient of variation. RESULTS: The valves performed as expected in simulation, providing a stable tidal volume of 400 ml each to two mannequins with compliance ratios varying from 20:20 to 20:90 ml/cm H2O. The system was then tested in two pairs of patients. Pair 1 was a 49-yr-old woman, ideal body weight 46 kg, and a 55-yr-old man, ideal body weight 64 kg, with lung compliance 27 ml/cm H2O versus 35 ml/cm H2O. The coefficient of variation for tidal volume was 0.2 to 1.7%, and for PMAX 0 to 1.1%. Pair 2 was a 32-yr-old man, ideal body weight 62 kg, and a 56-yr-old woman, ideal body weight 46 kg, with lung compliance 12 ml/cm H2O versus 21 ml/cm H2O. The coefficient of variation for tidal volume was 0.4 to 5.6%, and for PMAX 0 to 2.1%. CONCLUSIONS: Differential ventilation using a single ventilator is feasible. Flow control valves enable delivery of stable tidal volume and PMAX similar to those provided by individual ventilators.


Subject(s)
Coronavirus Infections/therapy , Pneumonia, Viral/therapy , Respiration, Artificial/methods , Ventilators, Mechanical , Acid-Base Equilibrium , Adult , COVID-19 , Continuous Positive Airway Pressure , Coronavirus Infections/complications , Feasibility Studies , Female , Humans , Lung Compliance , Male , Manikins , Middle Aged , Oxygen/blood , Pandemics , Pneumonia, Viral/complications , Positive-Pressure Respiration , Respiration, Artificial/instrumentation , Respiratory Insufficiency/etiology , Respiratory Insufficiency/therapy , Spirometry , Tidal Volume , Ventilators, Mechanical/supply & distribution
3.
Anesth Analg ; 130(3): e45-e48, 2020 03.
Article in English | MEDLINE | ID: mdl-31136328

ABSTRACT

Contamination of intravenous (IV) ports and stopcocks has been associated with postoperative infections. We tested the usability and efficacy of a novel passive shielding device to prevent such contamination even in the absence of hand hygiene or port disinfection. In a desktop setting with deliberately contaminated hands, qualitative port contamination was detected after 5/60 (8.3%; 95% confidence interval [CI], 2.8-18.4) control port injections versus 0/60 (0%; 95% CI, 0-6.0) shielded injections (P = .025). In clinical simulations with a quantitative bioburden assay (measured in relative light units [RLUs]), median (interquartile range [IQR]) postsimulation bioburden was 46 (32-53) vs 27 (21-42) RLU for the control versus intervention groups (P = .036), yielding a median shift of -13 RLU (95% CI, -2 to -26) in favor of the shielding. Usability of the device was acceptable to practitioners.


Subject(s)
Catheter-Related Infections/prevention & control , Catheterization, Central Venous/instrumentation , Catheterization, Peripheral/instrumentation , Catheters, Indwelling , Central Venous Catheters , Equipment Contamination , Hand/microbiology , Catheter-Related Infections/microbiology , Catheterization, Central Venous/adverse effects , Catheterization, Peripheral/adverse effects , Cross-Over Studies , Equipment Design , Humans , Materials Testing , Pilot Projects , Protective Factors , Risk Factors
4.
J Med Internet Res ; 22(3): e17425, 2020 03 12.
Article in English | MEDLINE | ID: mdl-32163038

ABSTRACT

BACKGROUND: The incidence of cardiac arrests per year in the United States continues to increase, yet in-hospital cardiac arrest survival rates significantly vary between hospitals. Current methods of training are expensive, time consuming, and difficult to scale, which necessitates improvements in advanced cardiac life support (ACLS) training. Virtual reality (VR) has been proposed as an alternative or adjunct to high-fidelity simulation (HFS) in several environments. No evaluations to date have explored the ability of a VR program to examine both technical and behavioral skills and demonstrate a cost comparison. OBJECTIVE: This study aimed to explore the utility of a voice-based VR ACLS team leader refresher as compared with HFS. METHODS: This prospective observational study performed at an academic institution consisted of 25 postgraduate year 2 residents. Participants were randomized to HFS or VR training and then crossed groups after a 2-week washout. Participants were graded on technical and nontechnical skills. Participants also completed self-assessments about the modules. Proctors were assessed for fatigue and task saturation, and cost analysis based on local economic data was performed. RESULTS: A total of 23 of 25 participants were included in the scoring analysis. Fewer participants were familiar with VR compared with HFS (9/25, 36% vs 25/25, 100%; P<.001). Self-reported satisfaction and utilization scores were similar; however, significantly more participants felt HFS provided better feedback: 99 (IQR 89-100) vs 79 (IQR 71-88); P<.001. Technical scores were higher in the HFS group; however, nontechnical scores for decision making and communication were not significantly different between modalities. VR sessions were 21 (IQR 19-24) min shorter than HFS sessions, the National Aeronautics and Space Administration task load index scores for proctors were lower in each category, and VR sessions were estimated to be US $103.68 less expensive in a single-learner, single-session model. CONCLUSIONS: Utilization of a VR-based team leader refresher for ACLS skills is comparable with HFS in several areas, including learner satisfaction. The VR module was more cost-effective and was easier to proctor; however, HFS was better at delivering feedback to participants. Optimal education strategies likely contain elements of both modalities. Further studies are needed to examine the utility of VR-based environments at scale.


Subject(s)
Advanced Cardiac Life Support/education , Clinical Competence/standards , Virtual Reality , Adult , Female , Humans , Male , Prospective Studies
5.
J Emerg Med ; 57(1): 51-58, 2019 Jul.
Article in English | MEDLINE | ID: mdl-31060845

ABSTRACT

BACKGROUND: Cardiopulmonary resuscitation (CPR) requires effective chest compressions and ventilations to circulate and oxygenate blood. It has been established that a 2-handed mask seal is superior when providing bag-valve-mask (BVM) ventilations. However a 1-handed technique remains the standard with which health care providers are trained to perform 2-rescuer CPR. OBJECTIVES: We sought to determine if a modified 2-rescuer CPR technique that incorporates a 2-handed mask seal during ventilations can be accomplished without compromising chest compression quality during a simulated cardiac arrest. METHODS: Medical student volunteers were divided into an "intervention" arm, with 1 rescuer creating a 2-handed mask seal and the second rescuer performing chest compressions followed by that second rescuer squeezing the BVM bag to deliver ventilations during compression pauses, and a "control" arm, in which standard 2-rescuer CPR was performed. Both arms received a brief CPR refresher following a standard script. The 2 rescuer teams then performed 2 rounds of CPR on a manikin while being video recorded. Data were collected from real-time evaluation and post hoc video analysis. RESULTS: Forty-seven pairs of students enrolled in the study. There were no statistically significant differences between the intervention and control arms for median (interquartile range [IQR]) compression fraction (72% [69.5-75.7%] vs. 73.2% [69.1-76.1%]; p = 1.0), median time to complete 2 rounds of CPR (207.8 s [198.5-222.9 s] vs. 214.7 s [201.3-219.5 s]; p = 0.625), median hands-off time (49.8 s [46.2-63.0 s] vs. 55.4 s [50.4-65.2 s]; p = 0.278), or median time for 30 compressions (15.2 s [14.3-15.9 s] vs. 15.4 s [14.6-16.3 s]; p = 0.452). CONCLUSION: Two-rescuer CPR incorporating a 2-handed face mask seal can be performed effectively without impacting chest compression quality during simulated cardiac arrest.


Subject(s)
Cardiopulmonary Resuscitation/methods , Cardiopulmonary Resuscitation/standards , Feasibility Studies , Humans , Manikins , Prospective Studies , Students, Medical/statistics & numerical data , Time Factors
6.
Immunol Invest ; 42(3): 247-61, 2013.
Article in English | MEDLINE | ID: mdl-23473375

ABSTRACT

Acute lung injury is defined as inadequate oxygenation of the blood due to primary and secondary injuries of the lungs that limit normal gas exchange across the alveolar capillary membrane. The etiology of this clinical syndrome is generally either infectious or non-infectious. Early detection of the underlying pathophysiology of the disease and timely initiation of antibiotic therapy is crucial for treatment of infectious causes of acute lung injury. Inflammatory biomarkers have recently gained popularity in critical care medicine to differentiate these two clinically similar entities. We have reviewed a variety of biomarkers related to acute lung injury and their relative value in early diagnosis and management of these patients.


Subject(s)
Acute Lung Injury/physiopathology , Biomarkers/blood , Critical Care/methods , Acute Lung Injury/blood , Acute Lung Injury/immunology , Animals , Cytokines/blood , Humans , Inflammation/blood , Inflammation/immunology , Inflammation/physiopathology , Lung/physiopathology , Mice
7.
Minerva Dent Oral Sci ; 72(2): 118-123, 2023 Apr.
Article in English | MEDLINE | ID: mdl-33929132

ABSTRACT

BACKGROUND: Long-term neurosensory dysfunction after mandibular fractures can have a significant impact on daily performances and quality of life (QoL) of the patient. The daily activities such as eating, speaking, shaving, kissing, and other social interactions can be affected due to the impaired sensation in the face and lip region. METHODS: A cross-sectional QoL assessment was done for the patients with inferior alveolar nerve dysfunction (IAND) from mandibular fractures at the 6-month follow-up visit. An interviewer-administered oral impacts on daily performances (OIDP) questionnaire was used. The OIDP scores were compared against the age and the severity of IAND. RESULTS: A total of 232 patients with mandibular fractures were initially examined, out of which 145 patients had IAND. At the end of 6 months, 52 patients still had some form of IAND and were included in this study. In our study, most affected activities were eating food (96.2%) and speaking clearly (98.1%) whereas the least affected were relaxing (9.6%) and doing major work (9.6%). Smiling (P<0.001), emotional state (P<0.001), and contact of other (P=0.02) were affected significantly more in younger patients than in older patients. Patients who had severe IAND at 6 months had problems with activities like cleaning teeth (P=0.04), doing light physical activity (P=0.007), going out (P=0.003), sleeping (P=0.012), and relaxing (P=0.03). CONCLUSIONS: Long-term IAND causes a significant impact on daily activities. This impact on QoL is particularly high and more frequent in the younger age group and patients with more severe IAND.


Subject(s)
Mandibular Fractures , Quality of Life , Humans , Aged , Oral Health , Cross-Sectional Studies , Surveys and Questionnaires
8.
J Maxillofac Oral Surg ; : 1-8, 2023 May 27.
Article in English | MEDLINE | ID: mdl-37362872

ABSTRACT

Rehabilitation in Low level maxillectomy cases has plethora of options right from local flaps to microvascular flaps. Subsequent to flap surgery, a maxillary dental rehabilitation can be demanding and a fixed or removable prosthesis is obligatory to provide them with near-normal function and aesthetics. Unlike the original ZIP flaps which were dedicated to microvascular flaps, we present here our unique experience with ZIP-Temporalis flap specifically for rehabilitation for patients of CAM (covid associated mucormycosis), its methods, advantages and limitations.

9.
J Orthop Trauma ; 37(2): 77-82, 2023 02 01.
Article in English | MEDLINE | ID: mdl-36001894

ABSTRACT

OBJECTIVE: To determine whether a reduced secondary operation rate offsets higher implant charges when using suture button fixation for syndesmotic injuries. DESIGN: Retrospective cohort study. SETTING: Single, urban, Level 1 trauma center. PARTICIPANTS: Three-hundred twenty-seven (N = 327) skeletally mature patients with rotational ankle fractures (OTA/AO type 44) necessitating concurrent syndesmotic fixation. INTERVENTION: Suture button or solid 3.5-mm screw syndesmotic fixation. MAIN OUTCOME MEASUREMENTS: To compare implant charges with secondary operation charges based on differential implant removal rates between screws and suture buttons. RESULTS: Patients undergoing screw fixation were older (48.8 vs. 39.6 years, P < 0.01), had more ground-level fall mechanisms (59.3% vs. 51.1%, P = 0.026), and sustained fewer 44C type injuries (34.7% vs. 56.8%, P = 0.01). Implant removal occurred at a higher rate in the screw fixation group (17.6% vs. 5.7%, P = 0.005). Binomial logistic regression identified nonsmoker status (B = 1.03, P = 0.04) and implant type (B = 1.41, P = 0.008) as factors associated with implant removal. Adjusting for age, the NNT with a suture button construct to prevent one implant removal operation was 9, with mean resulting additional implant charges of $9747 ($1083/case). Backward calculations using data from previous large studies estimated secondary operation charges at approximately $14220, suggesting a potential 31.5% cost savings for suture buttons when considering reduced secondary operation rates. CONCLUSIONS: A reduced secondary operation rate may offset increased implant charges for suture button syndesmotic fixation when considering institutional implant removal rates for operations occurring in tertiary care settings. Given these offsetting charges, surgeons should use the syndesmotic fixation strategy they deem most appropriate in their practice setting. LEVEL OF EVIDENCE: Economic Level IV. See Instructions for Authors for a complete description of levels of evidence.


Subject(s)
Ankle Fractures , Ankle Injuries , Humans , Retrospective Studies , Ankle Injuries/surgery , Ankle Fractures/surgery , Fracture Fixation, Internal/methods , Ankle Joint/surgery , Suture Techniques , Sutures
10.
J Orthop Trauma ; 37(1): 38-43, 2023 01 01.
Article in English | MEDLINE | ID: mdl-36518065

ABSTRACT

OBJECTIVES: To determine whether immediate weight bearing after intramedullary fixation of extra-articular proximal tibia fractures (OTA/AO 41A) results in change of alignment before union. DESIGN: Retrospective Review. SETTING: Level I and Level II Trauma Center. PATIENTS/PARTICIPANTS: Thirty-seven patients with 37 proximal tibial fractures, all whom could bear weight as tolerated postoperatively. Eighteen fractures were OTA/AO 41-A2, and 19 were OTA/AO 41-A3. INTERVENTION: Intramedullary nailing of extra-articular proximal tibia fractures. MAIN OUTCOME MEASUREMENTS: Change in fracture alignment or loss of reduction. RESULTS: The average change in coronal alignment at the final follow-up was 1.22 ± 1.28 degrees of valgus and 1.03 ± 1.05 degrees of extension in the sagittal plane. Twenty-five patients demonstrated excellent initial alignment, 10 patients demonstrated acceptable initial alignment, and 2 patients demonstrated poor initial alignment. Five patients demonstrated a change in alignment from excellent to acceptable at the final follow-up. No patient went from excellent or acceptable initial alignment to poor final alignment. Five patients required unplanned secondary surgical procedures. Two patients required return to the operating room for soft-tissue coverage procedures, 2 patients required surgical debridement of a postoperative infection, and 1 patient underwent debridement and exchange nailing of an infected nonunion. No patient underwent revision for implant failure or loss of reduction. CONCLUSION: Immediate weight bearing after intramedullary fixation of extra-articular proximal tibia fractures (OTA/AO 41A) led to minimal change in alignment at final postoperative radiographs. LEVEL OF EVIDENCE: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.


Subject(s)
Fracture Fixation, Intramedullary , Tibial Fractures , Humans , Tibia , Fracture Healing , Treatment Outcome , Fracture Fixation, Intramedullary/adverse effects , Fracture Fixation, Intramedullary/methods , Tibial Fractures/diagnostic imaging , Tibial Fractures/surgery , Weight-Bearing , Retrospective Studies
11.
J Orthop Trauma ; 37(6): 294-298, 2023 06 01.
Article in English | MEDLINE | ID: mdl-36728242

ABSTRACT

OBJECTIVE: To determine the outcomes after acute versus staged fixation of complete articular tibial plafond fractures. DESIGN: Retrospective cohort study. SETTING: Single Level 1 Trauma center. PARTICIPANTS: 98 skeletally mature patients with OTA/AO 43C type fractures who underwent definitive fixation with plate and screw constructs and had a minimum 6 months of follow-up. INTERVENTION: Acute open reduction internal fixation (aORIF) versus staged (sORIF) definitive fixation. MAIN OUTCOME MEASUREMENT: Rates of wound dehiscence/necrosis and deep infection. RESULTS: Acute (N = 40) versus staged (N = 58) ORIF groups had comparable rates of vascular disease, renal disease, and substance/nicotine use, but aORIF patients had higher rates of diabetes mellitus (10% vs. 0%, P < 0.001), which correlated with higher American Society of Anaesthesiologist scores (>American Society of Anaesthesiologist 3: 37.5% vs. 13.8%, P = 0.02). Both groups achieved anatomic/good reductions, as determined by postoperative CT scans, at rates greater than 90%; however, the sORIF group required modestly longer operative times to achieve this outcome (aORIF vs. sORIF: 121 vs. 146 minutes, P = 0.02). Postoperatively, both groups had similar rates of wound dehiscence (2.5% vs. 6.9%, P = 0.65), superficial infections (10% vs. 17.2%, P = 0.39), and deep infections (10% vs. 8.6%, P = 0.99). While the injury pattern itself required free flap coverage in 1 patient in each group, unplanned free flap coverage occurred in 10.0% and 10.3% of aORIF and sORIF groups, respectively. Overall, rates of unplanned reoperations, excluding ankle arthrodesis, did not differ between groups (aORIF vs. sORIF:12.5% vs. 25.9%, P = 0.13). CONCLUSIONS: In select patients managed by fellowship-trained orthopaedic traumatologists, acute definitive pilon fixation can produce acceptable outcomes. LEVEL OF EVIDENCE: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.


Subject(s)
Ankle Fractures , Tibial Fractures , Humans , Retrospective Studies , Treatment Outcome , Fracture Fixation, Internal/adverse effects , Tibial Fractures/diagnostic imaging , Tibial Fractures/surgery , Tibial Fractures/etiology , Ankle Fractures/diagnostic imaging , Ankle Fractures/surgery , Ankle Fractures/etiology , Postoperative Complications/epidemiology , Postoperative Complications/etiology
12.
J Orthop Trauma ; 37(5): 222-229, 2023 05 01.
Article in English | MEDLINE | ID: mdl-36821478

ABSTRACT

OBJECTIVE: To compare fracture patterns and associated injuries for young patients with high- versus low-energy intertrochanteric hip fractures and to report on factors associated with complications after surgical fixation of high-energy fractures. DESIGN: Retrospective comparative study. SETTING: Academic Level 1 Trauma Center. PATIENTS: A total of 103 patients 50 years of age or younger were included: 80 high-energy fractures and 23 low-energy fractures. INTERVENTION: Cephalomedullary nailing (N = 92) or a sliding hip screw (N = 11). MAIN OUTCOME MEASURES: Radiographic characteristics of fracture morphology, implant position, and reduction quality and postoperative complications were the main outcome measures. RESULTS: Compared with young patients with low-energy fractures, those with high-energy fractures had more fracture comminution ( P = 0.013) and higher ISS scores ( P < 0.003) and were more likely to require open reduction ( P < 0.001). Patients with low-energy fractures from a ground-level fall had higher rates of alcohol abuse (0.032), cirrhosis (0.010), and chronic steroid use (0.048). Overall reoperation rate for high-energy fractures was 7%, including 2 IT fracture nonunions (5%) and 1 deep infection (2%). For high-energy fractures, ASA class ( P = 0.026), anterior lag screw position ( P = 0.001), and varus malreduction ( P < 0.001) were associated with malunion. Four-part fracture (OTA/AO 31A2.3/Jensen 5) ( P = 0.028) and residual calcar gap >3 mm ( P = 0.03) were associated with reoperation. CONCLUSIONS: Surgical treatment of high-energy IT fractures in young patients is technically demanding with potential untoward outcomes. Injury characteristics and severity are significantly different for young patients with high-energy IT fractures compared with low-energy fractures. For young patients with a high-energy IT fracture, surgeons can anticipate a high rate of associated injuries and complex fracture patterns requiring open reduction. For young patients with a low-energy IT fracture, comanagement with a hospitalist or a geriatrician should be considered because they may be physiologically older. LEVEL OF EVIDENCE: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.


Subject(s)
Fracture Fixation, Intramedullary , Hip Fractures , Humans , Bone Nails , Bone Screws/adverse effects , Fracture Fixation, Intramedullary/adverse effects , Hip Fractures/diagnostic imaging , Hip Fractures/epidemiology , Hip Fractures/surgery , Retrospective Studies , Treatment Outcome
13.
J Anesth ; 26(6): 858-63, 2012 Dec.
Article in English | MEDLINE | ID: mdl-22752440

ABSTRACT

BACKGROUND: During the induction of anesthesia, patients are at risk of aspiration while awaiting full muscle relaxation. Magnesium has been shown to have synergistic effects with neuromuscular blocking drugs. We tested if magnesium, as an adjunct, increases the speed of onset of muscle relaxation, thereby decreasing the risk of aspiration. METHODS: Eighty-eight American Society of Anesthesiologists (ASA) physical status 1 or 2 patients were randomly assigned to three groups. Group Mg-0 received 100 mL of normal saline, whereas groups Mg-25 and Mg-50 received magnesium sulfate at doses of 25 and 50 mg/kg, respectively. Anesthesia was induced with thiopental 5 mg/kg and cisatracurium 0.15 mg/kg. A peripheral nerve stimulator and single-twitch test was performed on the ulnar nerve until the twitch responses to stimulation had disappeared, and the times were recorded. Then the patients were intubated and anesthesia was maintained with 100 µg/kg/min of propofol. The intensity of blockade was measured at regular time intervals with the post-tetanic count test. RESULTS: The mean times to muscle relaxation in groups Mg-0, Mg-25, and Mg-50 were 226, 209, and 188 s, respectively (P = 0.047). The intensity of the block increased with the dose of magnesium, and remained highest in group Mg-50 at all times measured (P < 0.05). The speed of onset and the intensity of muscle relaxation increased as higher doses of magnesium were used. CONCLUSION: The increased speed of onset of muscle relaxation produced by magnesium is not substantial enough to justify its use in combination with cisatracurium in rapid sequence induction.


Subject(s)
Anesthesia, General , Atracurium/analogs & derivatives , Magnesium Sulfate , Neuromuscular Blockade/methods , Neuromuscular Nondepolarizing Agents , Adolescent , Adult , Blood Pressure/drug effects , Double-Blind Method , Electric Stimulation , Female , Heart Rate/drug effects , Humans , Magnesium Sulfate/adverse effects , Male , Middle Aged , Monitoring, Intraoperative , Muscle Relaxation/drug effects , Prospective Studies , Sample Size , Young Adult
14.
Natl J Maxillofac Surg ; 13(2): 276-282, 2022.
Article in English | MEDLINE | ID: mdl-36051789

ABSTRACT

Background: After the clinical introduction of ultrasound scalpel in recent years, piezosurgery has become competitive with conventional instruments in orthognathic procedures to reduce the operative and postoperative complications reported to occur in association with these surgeries. Aims: The aim of this prospective clinical study was to compare intraoperative and postoperative outcomes of both piezoelectric device and the traditional bur technique in orthognathic surgery. Intraoperative bleeding time, operative time, postoperative swelling, and neurological impairment were evaluated. Materials and Methods: In this study, a split-mouth technique was applied on ten patients requiring orthognathic surgery. To make the osteotomy cuts, on the one side, piezo-osteotome was used, and on the other side, conventional osteotomy bur was used. Results: Duration of osteotomy was found to be greater with piezo osteotomy compared to bur osteotomy. Mild bleeding was observed with piezosurgery. Postoperative swelling was greater on the side of piezosurgery compared to the bur side. Altered neurosensory activity was found to be equal on the 1st day postoperatively, but the piezo side recovered faster compared to the bur side in the 1st month after surgery. Conclusion: Piezoelectric device offers better advantages over the conventional bur in orthognathic surgery and hence can be considered an alternative to the bur in some orthognathic procedures.

15.
J Orthop Trauma ; 36(2): 44-50, 2022 Feb 01.
Article in English | MEDLINE | ID: mdl-34554718

ABSTRACT

OBJECTIVE: To determine the effectiveness of various types of antibiotic-coated intramedullary implants in the treatment of septic long bone nonunion. DESIGN: Retrospective chart review. SETTING: Level 1 trauma center. PARTICIPANTS: Forty-one patients with septic long bone nonunion treated with an antibiotic cement-coated intramedullary implant. INTERVENTION: Surgical debridement and placement of a type of antibiotic-coated intramedullary implant. MAIN OUTCOME MEASUREMENTS: Union and need for reoperation. RESULTS: At an average 27-month follow-up (6-104), 27 patients (66%) had a modified radiographic union score of the tibia of 11.5 or greater, 12 patients (29%) a score lower than 11.5, and 2 patients (5%) underwent subsequent amputation. Six patients underwent no further surgical procedures after the index operation. Patients treated with a rigid, locked antibiotic nail achieved earlier weight-bearing (P = 0.001), less frequently required autograft (P = 0.005), and underwent fewer subsequent procedures (average 0.38 vs. 3.60, P = 0.004) than those treated with flexible core antibiotic rods. CONCLUSIONS: Antibiotic-coated intramedullary implants are successful in the treatment of septic nonunions in long bones. In our cohort, rigid, statically locked nails allowed faster rehabilitation, decreased the need for autograft, and decreased the number of additional surgical procedures. Further study is needed to confirm these findings. LEVEL OF EVIDENCE: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.


Subject(s)
Fracture Fixation, Intramedullary , Tibial Fractures , Anti-Bacterial Agents/therapeutic use , Bone Nails , Fracture Healing , Humans , Retrospective Studies , Tibial Fractures/diagnostic imaging , Tibial Fractures/drug therapy , Tibial Fractures/surgery , Treatment Outcome
16.
J Oral Maxillofac Surg ; 69(7): 2040-7, 2011 Jul.
Article in English | MEDLINE | ID: mdl-21458127

ABSTRACT

PURPOSE: To review retrospectively the benefits of using mandibulotomy as an access for tumors involving the maxilla and infratemporal fossa. PATIENTS AND METHODS: Twenty-four consecutive patients with tumors involving the maxilla and infratemporal fossa underwent maxillectomy through mandibular access osteotomy. Patient details and postoperative follow-up were reviewed and recorded. Postoperative complications such as neural morbidity and problems relevant to the procedure were evaluated. Ethical clearance from the medical practices board of the hospital was not required for this study. RESULTS: All but 1 patient underwent en bloc resection of the maxillary tumor with a histologically negative margin. One patient with adenoid cystic carcinoma had a positive orbital margin. Residual mouth opening smaller than 2.5 cm was observed in 4 patients. Healing of the osteotomy site was satisfactory in 21 patients. Three patients had osteotomy-related complications that required secondary intervention. Neural morbidity was temporary and cosmetic outcome of the procedure was excellent. CONCLUSION: Mandibular access osteotomy is an acceptable approach to tumors involving the maxilla and infratemporal fossa. The advantages of wide exposure, minimal morbidity, and good cosmesis make it superior to the conventional panfacial approach. This article highlights the advantages of this procedure and discusses conventional approaches with review of the literature.


Subject(s)
Mandible/surgery , Maxilla/surgery , Maxillary Neoplasms/surgery , Osteotomy/methods , Adult , Aged , Carcinoma, Adenoid Cystic/surgery , Carcinoma, Squamous Cell/surgery , Esthetics , Female , Follow-Up Studies , Humans , Lingual Nerve Injuries , Male , Middle Aged , Neck Dissection , Orbit/surgery , Postoperative Complications , Plastic Surgery Procedures , Reoperation , Retrospective Studies , Skull Neoplasms/surgery , Temporal Bone/surgery , Treatment Outcome , Trigeminal Nerve Injuries , Trismus/etiology , Wound Healing/physiology , Young Adult
17.
BMJ Case Rep ; 14(6)2021 Jun 14.
Article in English | MEDLINE | ID: mdl-34127499

ABSTRACT

Pleomorphic adenoma, otherwise called as benign mixed tumour, is the most common salivary gland tumour which accounts for 60% of all benign salivary gland tumours. The clinical, radiological and histopathological presentations are varied. The tumour occurs in diverse anatomical sites and can consist of epithelial and mesenchymal components. In this case report, the patient reported with an asymptomatic swelling on the face. CT scan with contrast was advised. The clinical, roentgenographic findings and Fine Needle Aspiration Cytology were indicative of pleomorphic adenoma of the parotid gland. Treatment included partial superficial parotidectomy under general anaesthesia using the modified Blair's incision. The facial nerve was not involved. Part of the gland along with the tumour was resected completely superficial to the facial nerve with a margin of normal tissue all around. Histopathologic examination of tissue specimen confirmed the lesion as pleomorphic adenoma. The patient was asymptomatic at 6-month follow-up.


Subject(s)
Adenoma, Pleomorphic , Parotid Neoplasms , Adenoma, Pleomorphic/diagnostic imaging , Adenoma, Pleomorphic/surgery , Facial Nerve , Humans , Parotid Gland/diagnostic imaging , Parotid Gland/surgery , Parotid Neoplasms/diagnostic imaging , Parotid Neoplasms/surgery , Salivary Glands
18.
Simul Healthc ; 16(1): 78-79, 2021 Feb 01.
Article in English | MEDLINE | ID: mdl-33086368

ABSTRACT

SUMMARY STATEMENT: The COVID-19 pandemic threatened to overwhelm the medical system of New York City, and the threat of ventilator shortages was real. Using high-fidelity simulation, a variety of solutions were tested to solve the problem of ventilator shortages including innovative designs for safely splitting ventilators, converting noninvasive ventilators to invasive ventilators, and testing and improving of ventilators created by outside companies. Simulation provides a safe environment for testing of devices and protocols before use on patients and should be vital in the preparation for emergencies such as the COVID-19 pandemic.


Subject(s)
COVID-19/epidemiology , Respiration, Artificial/methods , Simulation Training/organization & administration , Ventilators, Mechanical/supply & distribution , Humans , Pandemics , SARS-CoV-2
19.
J Korean Assoc Oral Maxillofac Surg ; 47(3): 183-189, 2021 Jun 30.
Article in English | MEDLINE | ID: mdl-34187958

ABSTRACT

OBJECTIVES: To assess the prevalence and recovery of inferior alveolar nerve dysfunction (IAND) in mandibular fractures. MATERIALS AND METHODS: : This was a prospective cohort study. Clinical neurosensory testing was done preoperatively and the IAND was categorized as mild, moderate or severe. Postoperatively, neurosensory testing was repeated at 1 day, 1 week, 1 month, 3 months and every 3 months thereafter. RESULTS: : A total of 257 patients with 420 fractures were included in the study with a mean age of 31.7 years. Body fractures (95.9%) had the highest incidence of IAND, followed by the angle fractures (90.1%) and symphysis fractures (27.6%). The condyle and coronoid fractures did not have any IAND and hence were excluded from further study. After eliminating those cases, 232 patients remained in the study with 293 fractures. The overall prevalence of IAND in fractures occurring distal to the mandibular foramen was 56.3%. The changes until 1 week were minimal. From 1 month to 6 months, there was a significant reduction in the severity of IAND. A significant number of cases (60.0%) were lost to follow-up between 6 and 9 months. At 6 months, 23.9% of cases still had some form of IAND and 95.0% of the symphysis, 59.0% of the angle and 34.8% of the body fractures with IAND had become normal. CONCLUSION: This study documents the reduction in the degree of severity of IAND in the first six months and provides the basis for future studies with longer periods of follow-up.

20.
J Orthop Trauma ; 35(6): 285-288, 2021 06 01.
Article in English | MEDLINE | ID: mdl-32976180

ABSTRACT

OBJECTIVE: To evaluate the difference in the quality of fracture reduction between the sinus tarsi approach (STA) and extensile lateral approach (ELA) using postoperative Computed Tomography (CT) scans in displaced intra-articular calcaneal fractures (DIACFs). DESIGN: Retrospective. SETTING: Level 1 and level 2 academic centers. PATIENTS: Consecutive patients undergoing operative fixation of DIACFs with postoperative CT scans and standard radiographs. METHODS: Patients were identified based on Current Procedural Terminology code and chart review. All operative calcaneal fractures treated between 2012 and 2018 by fellowship-trained orthopaedic trauma surgeons were evaluated. Those with both postoperative CT scans and radiographs were included. Exclusion criteria included extra-articular fractures, malunions, percutaneous fixation, ORIF and primary fusion, and those patients without a postoperative CT scan. The Sanders classification was used. Cases were divided into 2 groups based on ELA versus STA. Bohler angle and Gissane angle were evaluated on plain radiographs. CT reduction quality grading included articular step off/gap within the posterior facet, and varus angulation of the tuberosity: CT reduction grading included: excellent (E): no gap, no step, and no angulation; good (G): <1 mm step, <5 mm gap, and/or <5° of angulation, fair (F): 1-3 mm step, 5-10 mm gap, and/or 5-15° angulation; and poor (P): >3 mm step, >10 mm gap, and/or >15° angulation. RESULTS: Seventy-seven patients with 83 fractures were included. Average age was 42 years (range, 18-74 years), with 57 men. Four fractures were open. There were 37 Sanders II and 46 Sanders III fractures; 36 fractures were fixed using the STA, whereas 47 used the ELA. Average days to surgery were 5 for STA and 14 for ELA (P < 0.001). A normal Bohler angle was achieved more often with the ELA (91.5%) than with STA (77.8%) (P < 0.001). There was no difference by approach for Gissane angle (P = 0.5). ELA had better overall reduction quality (P = 0.02). For Sanders II, there was no difference in reduction quality with STA versus ELA (P = 0.51). For Sanders III, ELA trended toward better reduction quality (P = 0.06). CONCLUSIONS: The ELA had a better overall reduction of Bohler angle on plain radiographs and of the posterior facet and tuberosity on postoperative CT scans. For Sanders type II DIACFs, there was no difference between STA and ELA. Importantly, for Sanders III DIACFs, ELA trended toward better reduction quality. In addition to fracture reduction, surgeon learning curve, early wound complications, and long-term outcomes must be considered in future studies comparing the ELA and STA. LEVEL OF EVIDENCE: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.


Subject(s)
Calcaneus , Fractures, Bone , Intra-Articular Fractures , Adult , Calcaneus/diagnostic imaging , Calcaneus/surgery , Fracture Fixation, Internal , Fractures, Bone/diagnostic imaging , Fractures, Bone/surgery , Heel , Humans , Intra-Articular Fractures/diagnostic imaging , Intra-Articular Fractures/surgery , Male , Retrospective Studies , Treatment Outcome
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