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1.

An ABC transporter Wzm-Wzt catalyzes translocation of lipid-linked galactan across the plasma membrane in mycobacteria.

Savková, Karin; Huszár, Stanislav; Baráth, Peter; Pakanová, Zuzana; Kozmon, Stanislav; Vancová, Marie; Tesarová, Martina; Blasko, Jaroslav; Kalinák, Michal; Singh, Vinayak; Korduláková, Jana; Mikusová, Katarína.

Proc Natl Acad Sci U S A ; 118(17)2021 04 27.

Article in English | MEDLINE | ID: mdl-33879617

2.

Developing synergistic drug combinations to restore antibiotic sensitivity in drug-resistant Mycobacterium tuberculosis.

Omollo, Charles; Singh, Vinayak; Kigondu, Elizabeth; Wasuna, Antonina; Agarwal, Pooja; Moosa, Atica; Ioerger, Thomas R; Mizrahi, Valerie; Chibale, Kelly; Warner, Digby F.

Antimicrob Agents Chemother ; 65(5)2023 05 01.

Article in English | MEDLINE | ID: mdl-33619062

3.

Spiropyrimidinetriones: a Class of DNA Gyrase Inhibitors with Activity against Mycobacterium tuberculosis and without Cross-Resistance to Fluoroquinolones.

Basarab, Gregory S; Ghorpade, Sandeep; Gibhard, Liezl; Mueller, Rudolf; Njoroge, Mathew; Peton, Nashied; Govender, Preshendren; Massoudi, Lisa M; Robertson, Gregory Thomas; Lenaerts, Anne J; Boshoff, Helena Ingrid; Joerss, Douglas; Parish, Tanya; Durand-Reville, Thomas F; Perros, Manos; Singh, Vinayak; Chibale, Kelly.

Antimicrob Agents Chemother ; 66(4): e0219221, 2022 04 19.

Article in English | MEDLINE | ID: mdl-35266826

4.

Strategies to Combat Multi-Drug Resistance in Tuberculosis.

Singh, Vinayak; Chibale, Kelly.

Acc Chem Res ; 54(10): 2361-2376, 2021 05 18.

Article in English | MEDLINE | ID: mdl-33886255

5.

Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria.

Singh, Vinayak; Dhar, Neeraj; Pató, János; Kolly, Gaëlle S; Korduláková, Jana; Forbak, Martin; Evans, Joanna C; Székely, Rita; Rybniker, Jan; Palceková, Zuzana; Zemanová, Júlia; Santi, Isabella; Signorino-Gelo, François; Rodrigues, Liliana; Vocat, Anthony; Covarrubias, Adrian S; Rengifo, Monica G; Johnsson, Kai; Mowbray, Sherry; Buechler, Joseph; Delorme, Vincent; Brodin, Priscille; Knott, Graham W; Aínsa, José A; Warner, Digby F; Kéri, György; Mikusová, Katarína; McKinney, John D; Cole, Stewart T; Mizrahi, Valerie; Hartkoorn, Ruben C.

Mol Microbiol ; 103(1): 13-25, 2017 01.

Article in English | MEDLINE | ID: mdl-27677649

6.

Hit discovery of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase, GuaB2, inhibitors.

Sahu, Niteshkumar U; Singh, Vinayak; Ferraris, Davide M; Rizzi, Menico; Kharkar, Prashant S.

Bioorg Med Chem Lett ; 28(10): 1714-1718, 2018 06 01.

Article in English | MEDLINE | ID: mdl-29699922

7.

N-Acetylglucosamine-1-Phosphate Transferase, WecA, as a Validated Drug Target in Mycobacterium tuberculosis.

Huszár, Stanislav; Singh, Vinayak; Polcicová, Alica; Baráth, Peter; Barrio, María Belén; Lagrange, Sophie; Leblanc, Véronique; Nacy, Carol A; Mizrahi, Valerie; Mikusová, Katarína.

Antimicrob Agents Chemother ; 61(11)2017 11.

Article in English | MEDLINE | ID: mdl-28874370

8.

3D-QSAR and molecular modeling studies on 2,3-dideoxy hexenopyranosid-4-uloses as anti-tubercular agents targeting alpha-mannosidase.

Shah, Priyanka; Saquib, Mohammad; Sharma, Smriti; Husain, Irfan; Sharma, Sandeep K; Singh, Vinayak; Srivastava, Ranjana; Shaw, Arun K; Siddiqi, Mohammad Imran.

Bioorg Chem ; 59: 91-6, 2015 Apr.

Article in English | MEDLINE | ID: mdl-25727263

9.

Physicochemical analysis of Psophocarpus tetragonolobus (L.) DC seeds with fatty acids and total lipids compositions.

Mohanty, Chandra Sekhar; Pradhan, Rama Chandra; Singh, Vinayak; Singh, Neha; Pattanayak, Rojalin; Prakash, Om; Chanotiya, Chandan Singh; Rout, Prasant Kumar.

J Food Sci Technol ; 52(6): 3660-70, 2015 Jun.

Article in English | MEDLINE | ID: mdl-26028749

10.

Deoxysugars as antituberculars and alpha-mannosidase inhibitors.

Kashyap, Vivek; Sharma, Smriti; Singh, Vinayak; Sharma, Sandeep K; Saquib, Mohammad; Srivastava, Ranjana; Shaw, Arun K.

Antimicrob Agents Chemother ; 58(6): 3530-2, 2014 Jun.

Article in English | MEDLINE | ID: mdl-24687500

11.

Tuberculosis treatment-shortening.

Singh, Vinayak.

Drug Discov Today ; 29(5): 103955, 2024 May.

Article in English | MEDLINE | ID: mdl-38548262

12.

Unlocking Opportunities for Mycobacterium leprae and Mycobacterium ulcerans.

Shyam, Mousumi; Kumar, Sumit; Singh, Vinayak.

ACS Infect Dis ; 10(2): 251-269, 2024 02 09.

Article in English | MEDLINE | ID: mdl-38295025

13.

The implication of Mycobacterium tuberculosis-mediated metabolism of targeted xenobiotics.

Singh, Vinayak; Dziwornu, Godwin Akpeko; Chibale, Kelly.

Nat Rev Chem ; 7(5): 340-354, 2023 05.

Article in English | MEDLINE | ID: mdl-37117810

14.

Reducing the biosynthesis of condensed tannin in winged bean (Psophocarpus tetragonolobus (L.) DC.) by virus-induced gene silencing of anthocyanidin synthase (ANS) gene.

Singh, Vinayak; Lone, Rayees Ahmad; Kumar, Verandra; Mohanty, Chandra Sekhar.

3 Biotech ; 13(1): 16, 2023 Jan.

Article in English | MEDLINE | ID: mdl-36561838

15.

Recent developments of imidazo[1,2-a]pyridine analogues as antituberculosis agents.

Samanta, Sauvik; Kumar, Sumit; Aratikatla, Eswar K; Ghorpade, Sandeep R; Singh, Vinayak.

RSC Med Chem ; 14(4): 644-657, 2023 Apr 26.

Article in English | MEDLINE | ID: mdl-37122538

16.

Phospholipase C: underrated players in microbial infections.

Singh, Vinayak; Rai, Rupal; Mathew, Bijina J; Chourasia, Rashmi; Singh, Anirudh K; Kumar, Awanish; Chaurasiya, Shivendra K.

Front Cell Infect Microbiol ; 13: 1089374, 2023.

Article in English | MEDLINE | ID: mdl-37139494

17.

Implications of Mycobacterium tuberculosis Metabolic Adaptability on Drug Discovery and Development.

Cardoso, Nicole C; Chibale, Kelly; Singh, Vinayak.

ACS Infect Dis ; 8(3): 414-421, 2022 03 11.

Article in English | MEDLINE | ID: mdl-35175727

18.

Innovation Experiences from Africa-Led Drug Discovery at the Holistic Drug Discovery and Development (H3D) Centre.

Singh, Vinayak; Mambwe, Dickson; Korkor, Constance Mawunyo; Chibale, Kelly.

ACS Med Chem Lett ; 13(8): 1221-1230, 2022 Aug 11.

Article in English | MEDLINE | ID: mdl-35978699

19.

Mycobacterial response to an acidic environment: protective mechanisms.

Rai, Rupal; Singh, Vinayak; Mathew, Bijina J; Singh, Anirudh K; Chaurasiya, Shivendra K.

Pathog Dis ; 80(1)2022 10 03.

Article in English | MEDLINE | ID: mdl-35953394

20.

Localized efficacy of environmental RNAi in Tetranychus urticae.

Bensoussan, Nicolas; Milojevic, Maja; Bruinsma, Kristie; Dixit, Sameer; Pham, Sean; Singh, Vinayak; Zhurov, Vladimir; Grbic, Miodrag; Grbic, Vojislava.

Sci Rep ; 12(1): 14791, 2022 08 30.

Article in English | MEDLINE | ID: mdl-36042376

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