ABSTRACT
The NCCN Guidelines for Colorectal Cancer (CRC) Screening outline various screening modalities as well as recommended screening strategies for individuals at average or increased-risk of developing sporadic CRC. The NCCN panel meets at least annually to review comments from reviewers within their institutions, examine relevant data, and reevaluate and update their recommendations. These NCCN Guidelines Insights summarize 2018 updates to the NCCN Guidelines, with a primary focus on modalities used to screen individuals at average-risk for CRC.
Subject(s)
Colorectal Neoplasms/diagnosis , Early Detection of Cancer/statistics & numerical data , Mass Screening/standards , Medical Oncology/standards , Age Factors , Aged , Aged, 80 and over , Biomarkers, Tumor/blood , Biomarkers, Tumor/genetics , Biomarkers, Tumor/isolation & purification , Colonoscopy/methods , Colonoscopy/standards , Colorectal Neoplasms/blood , Colorectal Neoplasms/genetics , Colorectal Neoplasms/pathology , DNA, Neoplasm/genetics , DNA, Neoplasm/isolation & purification , Early Detection of Cancer/methods , Feces/chemistry , Humans , Immunochemistry/methods , Immunochemistry/standards , Mass Screening/methods , Medical Oncology/methods , Middle Aged , Occult Blood , Randomized Controlled Trials as Topic , Septins/genetics , Societies, Medical/standards , Time Factors , Tomography, X-Ray Computed/methods , Tomography, X-Ray Computed/standards , United StatesABSTRACT
The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations for the management of patients with high-risk syndromes associated with an increased risk of colorectal cancer (CRC). The NCCN Panel for Genetic/Familial High-Risk Assessment: Colorectal meets at least annually to assess comments from reviewers within their institutions, examine relevant data, and reevaluate and update their recommendations. These NCCN Guidelines Insights focus on genes newly associated with CRC risk on multigene panels, the associated evidence, and currently recommended management strategies.