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1.

A light-inducible protein clustering system for in vivo analysis of α-synuclein aggregation in Parkinson disease.

Bérard, Morgan; Sheta, Razan; Malvaut, Sarah; Rodriguez-Aller, Raquel; Teixeira, Maxime; Idi, Walid; Turmel, Roxanne; Alpaugh, Melanie; Dubois, Marilyn; Dahmene, Manel; Salesse, Charleen; Lamontagne-Proulx, Jérôme; St-Pierre, Marie-Kim; Tavassoly, Omid; Luo, Wen; Del Cid-Pellitero, Esther; Qazi, Raza; Jeong, Jae-Woong; Durcan, Thomas M; Vallières, Luc; Tremblay, Marie-Eve; Soulet, Denis; Lévesque, Martin; Cicchetti, Francesca; Fon, Edward A; Saghatelyan, Armen; Oueslati, Abid.

PLoS Biol ; 20(3): e3001578, 2022 03.

Article in English | MEDLINE | ID: mdl-35263320

2.

Heparin-binding Peptides as Novel Therapies to Stop SARS-CoV-2 Cellular Entry and Infection.

Tavassoly, Omid; Safavi, Farinaz; Tavassoly, Iman.

Mol Pharmacol ; 98(5): 612-619, 2020 11.

Article in English | MEDLINE | ID: mdl-32913137

3.

Inhibition of Brain Epidermal Growth Factor Receptor Activation: A Novel Target in Neurodegenerative Diseases and Brain Injuries.

Tavassoly, Omid; Sato, Takashi; Tavassoly, Iman.

Mol Pharmacol ; 98(1): 13-22, 2020 07.

Article in English | MEDLINE | ID: mdl-32350120

4.

SMPD1 mutations, activity, and α-synuclein accumulation in Parkinson's disease.

Alcalay, Roy N; Mallett, Victoria; Vanderperre, Benoît; Tavassoly, Omid; Dauvilliers, Yves; Wu, Richard Y J; Ruskey, Jennifer A; Leblond, Claire S; Ambalavanan, Amirthagowri; Laurent, Sandra B; Spiegelman, Dan; Dionne-Laporte, Alexandre; Liong, Christopher; Levy, Oren A; Fahn, Stanley; Waters, Cheryl; Kuo, Sheng-Han; Chung, Wendy K; Ford, Blair; Marder, Karen S; Kang, Un Jung; Hassin-Baer, Sharon; Greenbaum, Lior; Trempe, Jean-Francois; Wolf, Pavlina; Oliva, Petra; Zhang, Xiaokui Kate; Clark, Lorraine N; Langlois, Melanie; Dion, Patrick A; Fon, Edward A; Dupre, Nicolas; Rouleau, Guy A; Gan-Or, Ziv.

Mov Disord ; 34(4): 526-535, 2019 04.

Article in English | MEDLINE | ID: mdl-30788890

5.

Pharmacological Functionalization of Protein-Based Nanorobots as a Novel Tool for Drug Delivery in Cancer.

Tavassoly, Omid; Tavassoly, Iman.

ACS Pharmacol Transl Sci ; 4(4): 1463-1467, 2021 Aug 13.

Article in English | MEDLINE | ID: mdl-34423277

6.

EGFR Aggregation in the Brain.

Tavassoly, Omid; Tavassoly, Iman.

ACS Chem Neurosci ; 12(11): 1833-1834, 2021 06 02.

Article in English | MEDLINE | ID: mdl-33979124

7.

Pharmacological inhibition and knockdown of O-GlcNAcase reduces cellular internalization of α-synuclein preformed fibrils.

Tavassoly, Omid; Yue, Jefferey; Vocadlo, David J.

FEBS J ; 288(2): 452-470, 2021 01.

Article in English | MEDLINE | ID: mdl-32365408

8.

Pharmacological Inhibition of Brain EGFR Activation By a BBB-penetrating Inhibitor, AZD3759, Attenuates α-synuclein Pathology in a Mouse Model of α-Synuclein Propagation.

Tavassoly, Omid; Del Cid Pellitero, Esther; Larroquette, Frederique; Cai, Eddie; Thomas, Rhalena A; Soubannier, Vincent; Luo, Wen; Durcan, Thomas M; Fon, Edward A.

Neurotherapeutics ; 18(2): 979-997, 2021 04.

Article in English | MEDLINE | ID: mdl-33713002

9.

Seeding Brain Protein Aggregation by SARS-CoV-2 as a Possible Long-Term Complication of COVID-19 Infection.

Tavassoly, Omid; Safavi, Farinaz; Tavassoly, Iman.

ACS Chem Neurosci ; 11(22): 3704-3706, 2020 11 18.

Article in English | MEDLINE | ID: mdl-33147014

10.

Seeding of proteins into amyloid structures by metabolite assemblies may clarify certain unexplained epidemiological associations.

Sade, Dorin; Shaham-Niv, Shira; Arnon, Zohar A; Tavassoly, Omid; Gazit, Ehud.

Open Biol ; 8(1)2018 01.

Article in English | MEDLINE | ID: mdl-29367352

11.

Quinolinic Acid Amyloid-like Fibrillar Assemblies Seed α-Synuclein Aggregation.

Tavassoly, Omid; Sade, Dorin; Bera, Santu; Shaham-Niv, Shira; Vocadlo, David J; Gazit, Ehud.

J Mol Biol ; 430(20): 3847-3862, 2018 10 12.

Article in English | MEDLINE | ID: mdl-30098337

12.

Rasagiline, a suicide inhibitor of monoamine oxidases, binds reversibly to α-synuclein.

Kakish, Joe; Tavassoly, Omid; Lee, Jeremy S.

ACS Chem Neurosci ; 6(2): 347-55, 2015 Feb 18.

Article in English | MEDLINE | ID: mdl-25514361

13.

The use of nanopore analysis for discovering drugs which bind to α-synuclein for treatment of Parkinson's disease.

Tavassoly, Omid; Kakish, Joe; Nokhrin, Sergiy; Dmitriev, Oleg; Lee, Jeremy S.

Eur J Med Chem ; 88: 42-54, 2014 Dec 17.

Article in English | MEDLINE | ID: mdl-25081642

14.

Cu(II) and dopamine bind to α-synuclein and cause large conformational changes.

Tavassoly, Omid; Nokhrin, Sergiy; Dmitriev, Oleg Y; Lee, Jeremy S.

FEBS J ; 281(12): 2738-53, 2014 Jun.

Article in English | MEDLINE | ID: mdl-24725464

15.

Methamphetamine binds to α-synuclein and causes a conformational change which can be detected by nanopore analysis.

Tavassoly, Omid; Lee, Jeremy S.

FEBS Lett ; 586(19): 3222-8, 2012 Sep 21.

Article in English | MEDLINE | ID: mdl-22771474

16.

Nanopore analysis: An emerging technique for studying the folding and misfolding of proteins.

Madampage, Claudia; Tavassoly, Omid; Christensen, Chris; Kumari, Meena; Lee, Jeremy S.

Prion ; 6(2): 116-23, 2012.

Article in English | MEDLINE | ID: mdl-22421211

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