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1.

Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies.

Chew, Hui Yi; De Lima, Priscila O; Gonzalez Cruz, Jazmina L; Banushi, Blerida; Echejoh, Godwins; Hu, Lingbo; Joseph, Shannon R; Lum, Benedict; Rae, James; O'Donnell, Jake S; Merida de Long, Lilia; Okano, Satomi; King, Brigid; Barry, Rachael; Moi, Davide; Mazzieri, Roberta; Thomas, Ranjeny; Souza-Fonseca-Guimaraes, Fernando; Foote, Matthew; McCluskey, Adam; Robinson, Phillip J; Frazer, Ian H; Saunders, Nicholas A; Parton, Robert G; Dolcetti, Riccardo; Cuff, Katharine; Martin, Jennifer H; Panizza, Benedict; Walpole, Euan; Wells, James W; Simpson, Fiona.

Cell ; 180(5): 895-914.e27, 2020 03 05.

Article in English | MEDLINE | ID: mdl-32142680

2.

MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the Microbiota.

Koyama, Motoko; Mukhopadhyay, Pamela; Schuster, Iona S; Henden, Andrea S; Hülsdünker, Jan; Varelias, Antiopi; Vetizou, Marie; Kuns, Rachel D; Robb, Renee J; Zhang, Ping; Blazar, Bruce R; Thomas, Ranjeny; Begun, Jakob; Waddell, Nicola; Trinchieri, Giorgio; Zeiser, Robert; Clouston, Andrew D; Degli-Esposti, Mariapia A; Hill, Geoffrey R.

Immunity ; 51(5): 885-898.e7, 2019 11 19.

Article in English | MEDLINE | ID: mdl-31542340

3.

IDH-mutant myeloid neoplasms are associated with seronegative rheumatoid arthritis and innate immune activation.

Hong, Lih En; Wechalekar, Mihir D; Kutyna, Monika; Small, Annabelle; Lim, Kelly; Thompson-Peach, Chloe; Li, Joule J; Chhetri, Rakchha; Scott, Hamish S; Brown, Anna; Hahn, Christopher N; Yeung, David T; Sajid, Salvia; Robinson, Nirmal; Thomas, Ranjeny; Branford, Susan; D'Andrea, Richard J; Samaraweera, Saumya E; Patnaik, Mrinal; Proudman, Susanna; Thomas, Daniel; Kok, Chung Hoow; Shah, Mithun V; Hiwase, Devendra K.

Blood ; 143(18): 1873-1877, 2024 May 02.

Article in English | MEDLINE | ID: mdl-38457663

4.

Liposomal delivery of self-peptide and calcitriol as tolerogenic immunotherapy in rheumatoid arthritis: an exploration using sensory science.

Hee, Jia Yi; Cai, Benjamin; Thomas, Ranjeny.

Immunol Cell Biol ; 102(5): 353-357, 2024.

Article in English | MEDLINE | ID: mdl-38216149

5.

CD8⁺ tissue-resident memory T cells are expanded in primary Sjögren's disease and can be therapeutically targeted by CD103 blockade.

Mauro, Daniele; Lin, Xiang; Pontarini, Elena; Wehr, Pascale; Guggino, Giuliana; Tang, Yuan; Deng, Chong; Gandolfo, Saviana; Xiao, Fan; Rui, Ke; Huang, Enyu; Tian, Jie; Raimondo, Stefania; Rischmueller, Maureen; Boroky, Jane; Downie-Doyle, Sarah; Nel, Hendrik; Baz-Morelli, Adriana; Hsu, Arthur; Maraskovsky, Eugene; Barr, Adele; Hemon, Patrice; Chatzis, Loukas; Boschetti, Ciro Emiliano; Colella, Giuseppe; Alessandro, Riccardo; Rizzo, Aroldo; Pers, Jacques-Olivier; Bombardieri, Michele; Thomas, Ranjeny; Lu, Liwei; Ciccia, Francesco.

Ann Rheum Dis ; 2024 May 22.

Article in English | MEDLINE | ID: mdl-38777379

6.

Genetically encoded Runx3 and CD4⁺ intestinal epithelial lymphocyte deficiencies link SKG mouse and human predisposition to spondyloarthropathy.

Bhuyan, Zaied Ahmed; Rahman, M Arifur; Maradana, Muralidhara Rao; Mehdi, Ahmed M; Bergot, Anne-Sophie; Simone, Davide; El-Kurdi, Marya; Garrido-Mesa, Jose; Cai, Cheng Bang Benjamin; Cameron, Amy J; Hanson, Aimee L; Nel, Hendrik J; Kenna, Tony; Leo, Paul; Rehaume, Linda; Brown, Matthew A; Ciccia, Francesco; Thomas, Ranjeny.

Clin Immunol ; 247: 109220, 2023 02.

Article in English | MEDLINE | ID: mdl-36596403

7.

Antigen-specific immunotherapy to restore antigen-specific tolerance in Type 1 diabetes and Graves' disease.

Zala, Aakansha; Thomas, Ranjeny.

Clin Exp Immunol ; 211(2): 164-175, 2023 03 16.

Article in English | MEDLINE | ID: mdl-36545825

8.

Tolerance induction by liposomes targeting a single CD8 epitope IGRP_206-214 in a model of type 1 diabetes is impeded by co-targeting a CD4⁺ islet epitope.

Buckle, Irina; Loaiza Naranjo, Jeniffer D; Bergot, Anne-Sophie; Zhang, Vivian; Talekar, Meghna; Steptoe, Raymond J; Thomas, Ranjeny; Hamilton-Williams, Emma E.

Immunol Cell Biol ; 100(1): 33-48, 2022 01.

Article in English | MEDLINE | ID: mdl-34668580

9.

Evaluation of a fit-for-purpose assay to monitor antigen-specific functional CD4+ T-cell subpopulations in rheumatoid arthritis using flow cytometry-based peptide-MHC class-II tetramer staining.

Patel, Swati; Ramnoruth, Nishta; Wehr, Pascale; Rossjohn, Jamie; Reid, Hugh H; Campbell, Kim; Nel, Hendrik J; Thomas, Ranjeny.

Clin Exp Immunol ; 207(1): 72-83, 2022 01 28.

Article in English | MEDLINE | ID: mdl-35020859

10.

Regulatory T Cells Induced by Single-Peptide Liposome Immunotherapy Suppress Islet-Specific T Cell Responses to Multiple Antigens and Protect from Autoimmune Diabetes.

Bergot, Anne-Sophie; Buckle, Irina; Cikaluru, Sumana; Naranjo, Jennifer Loaiza; Wright, Casey Maree; Zheng, Guoliang; Talekar, Meghna; Hamilton-Williams, Emma E; Thomas, Ranjeny.

J Immunol ; 204(7): 1787-1797, 2020 04 01.

Article in English | MEDLINE | ID: mdl-32111734

11.

Rheumatoid arthritis is a preventable disease: 11 ways to reduce your patients' risk.

Koller-Smith, Louise; Mehdi, Ahmed M; March, Lyn; Tooth, Leigh; Mishra, Gita D; Thomas, Ranjeny.

Intern Med J ; 52(5): 711-716, 2022 05.

Article in English | MEDLINE | ID: mdl-34553824

12.

Reinforcing the Checkpoint in Rheumatoid Arthritis.

Gravallese, Ellen M; Thomas, Ranjeny.

N Engl J Med ; 388(20): 1905-1907, 2023 May 18.

Article in English | MEDLINE | ID: mdl-37195948

13.

Preclinical models of arthritis for studying immunotherapy and immune tolerance.

Meehan, Gavin R; Thomas, Ranjeny; Al Khabouri, Shaima; Wehr, Pascale; Hilkens, Catharien Mu; Wraith, David C; Sieghart, Daniela; Bonelli, Michael; Nagy, György; Garside, Paul; Tough, David F; Lewis, Huw D; Brewer, James M.

Ann Rheum Dis ; 80(10): 1268-1277, 2021 10.

Article in English | MEDLINE | ID: mdl-34380700

14.

Streptococcus species enriched in the oral cavity of patients with RA are a source of peptidoglycan-polysaccharide polymers that can induce arthritis in mice.

Moentadj, Rabia; Wang, Yiwen; Bowerman, Kate; Rehaume, Linda; Nel, Hendrik; O Cuiv, Paraic; Stephens, Juliette; Baharom, Amalina; Maradana, Muralidhara; Lakis, Vanessa; Morrison, Mark; Wells, Timothy; Hugenholtz, Philip; Benham, Helen; Le Cao, Kim-Anh; Thomas, Ranjeny.

Ann Rheum Dis ; 80(5): 573-581, 2021 05.

Article in English | MEDLINE | ID: mdl-33397732

15.

RelB suppresses type I Interferon signaling in dendritic cells.

Saha, Irene; Jaiswal, Hemant; Mishra, Richa; Nel, Hendrik J; Schreuder, Jaring; Kaushik, Monika; Singh Chauhan, Kuldeep; Singh Rawat, Bhupendra; Thomas, Ranjeny; Naik, Shalin; Kumar, Himanshu; Tailor, Prafullakumar.

Cell Immunol ; 349: 104043, 2020 03.

Article in English | MEDLINE | ID: mdl-32044112

16.

The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.

Ting, Yi Tian; Petersen, Jan; Ramarathinam, Sri H; Scally, Stephen W; Loh, Khai L; Thomas, Ranjeny; Suri, Anish; Baker, Daniel G; Purcell, Anthony W; Reid, Hugh H; Rossjohn, Jamie.

J Biol Chem ; 293(9): 3236-3251, 2018 03 02.

Article in English | MEDLINE | ID: mdl-29317506

17.

IL-23 favours outgrowth of spondyloarthritis-associated pathobionts and suppresses host support for homeostatic microbiota.

Rehaume, Linda M; Matigian, Nicholas; Mehdi, Ahmed M; Lachner, Nancy; Bowerman, Kate L; Daly, Joshua; Lê Cao, Kim-Anh; Hugenholtz, Philip; Thomas, Ranjeny.

Ann Rheum Dis ; 78(4): 494-503, 2019 04.

Article in English | MEDLINE | ID: mdl-30700427

18.

An improved clinical model to predict stimulated C-peptide in children with recent-onset type 1 diabetes.

Buchanan, Kerry; Mehdi, Ahmed M; Hughes, Ian; Cotterill, Andrew; Le Cao, Kim-Anh; Thomas, Ranjeny; Harris, Mark.

Pediatr Diabetes ; 20(2): 166-171, 2019 03.

Article in English | MEDLINE | ID: mdl-30556344

19.

RelB-Deficient Dendritic Cells Promote the Development of Spontaneous Allergic Airway Inflammation.

Nair, Prema M; Starkey, Malcolm R; Haw, Tatt Jhong; Ruscher, Roland; Liu, Gang; Maradana, Muralidhara R; Thomas, Ranjeny; O'Sullivan, Brendan J; Hansbro, Philip M.

Am J Respir Cell Mol Biol ; 58(3): 352-365, 2018 03.

Article in English | MEDLINE | ID: mdl-28960101

20.

Treatment delays for patients with new-onset rheumatoid arthritis presenting to an Australian early arthritis clinic.

Ison, Matthew; Duggan, Emily; Mehdi, Ahmed; Thomas, Ranjeny; Benham, Helen.

Intern Med J ; 48(12): 1498-1504, 2018 Dec.

Article in English | MEDLINE | ID: mdl-29808525

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