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1.
Laryngoscope ; 2024 Jun 07.
Article in English | MEDLINE | ID: mdl-38847090

ABSTRACT

Ewing sarcoma of the larynx is extremely rare, only a few number of cases have been reported. In this report, we describe a case of extraskeletal Ewing sarcoma of the larynx with thyroid cartilage destruction. Laryngoscope, 2024.

2.
Magy Onkol ; 68(2): 171-176, 2024 Jul 16.
Article in Hungarian | MEDLINE | ID: mdl-39013091

ABSTRACT

Previous twin studies show that genetic factors are responsible for 63% of the variability in breast density. We analyzed the mammographic images of 9 discordant twin pairs for breast cancer from the population-based Hungarian Twin Registry. We measured breast density using 3D Slicer software. Genetic variants predisposing to breast cancer were also examined. One of the examined twin pairs had a BRCA2 mutation in both members. There was no significant difference between the mean values of breast density in the tumor and non-tumor groups (p=0.323). In terms of parity and the presence of menopause, we found mostly no significant difference between the members of the twin pair. In our cohort of identical twins discordant for breast cancer, the average breast density showed no significant difference, which can be explained by the common genetic basis of breast cancer and breast density.


Subject(s)
Breast Density , Breast Neoplasms , Mammography , Humans , Female , Breast Neoplasms/genetics , Breast Neoplasms/pathology , Breast Neoplasms/diagnostic imaging , Hungary , Middle Aged , Twins, Monozygotic/genetics , Adult , Genetic Predisposition to Disease , Registries , BRCA2 Protein/genetics , Aged , Diseases in Twins/genetics , Diseases in Twins/epidemiology , Mutation , Breast/diagnostic imaging , Breast/pathology
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