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1.
Reverse Sequence Syphilis Screening and Discordant Results in Pregnancy.
Williams, Jessica E P; Bazan, José A; Turner, Abigail Norris; Thung, Stephen F; Hanlon, Cory; Pettus, Tanisha R; Sánchez, Pablo J.
J Pediatr ; 219: 263-266.e1, 2020 04.
Article in English | MEDLINE | ID: mdl-32093931

ABSTRACT

A "reverse sequence syphilis screening" algorithm is widely used for syphilis testing. This retrospective study showed that most (65%) pregnant women with discordant screening results (treponemal multiplex flow immunoassay IgG+/rapid plasma reagin-) had a nonreactive confirmatory Treponema pallidum-particle agglutination assay, likely indicative of a false-positive reaction.


Subject(s)
Pregnancy Complications, Infectious/diagnosis , Syphilis Serodiagnosis/methods , Syphilis/diagnosis , Adult , Algorithms , False Positive Reactions , Female , Humans , Pregnancy , Retrospective Studies , Young Adult
2.
Maternal and Congenital Syphilis: A Call for Improved Diagnostics and Education.
Williams, Jessica E P; Graf, Rachel J; Miller, Charles A; Michelow, Ian C; Sánchez, Pablo J.
Pediatrics ; 150(3)2022 09 01.
Article in English | MEDLINE | ID: mdl-36000327

Subject(s)
Pregnancy Complications, Infectious , Syphilis, Congenital , Syphilis , Female , Humans , Infectious Disease Transmission, Vertical/prevention & control , Mass Screening , Pregnancy , Pregnancy Complications, Infectious/diagnosis , Syphilis, Congenital/diagnosis , Syphilis, Congenital/transmission
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