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1.
Psychol Med ; 53(12): 5756-5766, 2023 09.
Article in English | MEDLINE | ID: mdl-36154947

ABSTRACT

BACKGROUND: It is unclear whether the enhancing contact model (ECM) intervention is effective in reducing family caregiving burden and improving hope and quality of life (QOL) among family caregivers of persons with schizophrenia (FCPWS). METHODS: We conducted a cluster randomized controlled trial in FCPWS in eight rural townships in Xinjin, Chengdu, China. In total, 253 FCPWS were randomly allocated to the ECM, psychoeducational family intervention (PFI), or treatment as usual (TAU) group. FCPWS in three groups were assessed caregiving burden, QOL and state of hope at baseline (T0), post-intervention (T1), 3-month (T2), and 9-month (T3) follow-up, respectively. RESULTS: Compared with participants in the TAU group, participants in the ECM group had statistically significantly lower caregiving burden scores both at T1 and T2 (p = 0.0059 and 0.0257, respectively). Compared with participants in the TAU group, participants in the PFI group had statistically significantly higher QOL scores in T1 (p = 0.0406), while participants in the ECM group had statistically significantly higher QOL scores in T3 (p = 0.0240). Participants in both ECM and PFI groups had statistically significantly higher hope scores than those in the TAU group at T1 (p = 0.0160 and 0.0486, respectively). CONCLUSIONS: This is the first study to explore the effectiveness of ECM on reducing family caregiving burden and improving hope and QOL in rural China. The results indicate the ECM intervention, a comprehensive and multifaceted intervention, is more effective than the PFI in various aspects of mental wellbeing among FCPWS. Future research needs to confirm ECM's effectiveness in various population.


Subject(s)
Caregivers , Schizophrenia , Humans , Caregivers/psychology , Schizophrenia/therapy , Schizophrenia/epidemiology , Quality of Life , Family/psychology , China/epidemiology
2.
Glycoconj J ; 38(1): 1-11, 2021 02.
Article in English | MEDLINE | ID: mdl-33547992

ABSTRACT

The prevalence of oral squamous cell carcinoma (OSCC) is high in South and Southeast Asia regions. Most OSCC patients are detected at advanced stages low 5-year survival rates. Aberrant expression of glycosylated proteins was found to be associated with malignant transformation and cancer progression. Hence, identification of cancer-associated glycoproteins could be used as potential biomarkers that are beneficial for diagnosis or clinical management of patients. This study aims to identify the differentially expressed glycoproteins using lectin-based glycoproteomics approaches. Serum samples of 40 patients with OSCC, 10 patients with oral potentially malignant disorder (OPMD), and 10 healthy individuals as control group were subjected to two-dimensional gel electrophoresis (2-DE) coupled with lectin Concanavalin A and Jacalin that specifically bind to N- and O-glycosylated proteins, respectively. Five differentially expressed N- and O-glycoproteins with various potential glycosylation sites were identified, namely N-glycosylated α1-antitrypsin (AAT), α2-HS-glycoprotein (AHSG), apolipoprotein A-I (APOA1), and haptoglobin (HP); as well as O-glycosylated AHSG and clusterin (CLU). Among them, AAT and APOA1 were further validated using enzyme-linked immunosorbent assay (ELISA) (n = 120). It was found that AAT and APOA1 are significantly upregulated in OSCC and these glycoproteins are independent risk factors of OSCC. The clinical utility of AAT and APOA1 as potential biomarkers of OSCC is needed for further evaluation.


Subject(s)
Biomarkers, Tumor/blood , Carcinoma, Squamous Cell/blood , Glycoproteins/blood , Mouth Neoplasms/blood , Adult , Aged , Apolipoprotein A-I/blood , Apolipoprotein A-I/metabolism , Case-Control Studies , Chromatography, Affinity/methods , Chromatography, Agarose/methods , Concanavalin A , Enzyme-Linked Immunosorbent Assay , Female , Glycoproteins/metabolism , Glycosylation , Humans , Male , Mass Spectrometry , Middle Aged , Plant Lectins/metabolism , Precancerous Conditions/blood , Squamous Cell Carcinoma of Head and Neck , alpha 1-Antitrypsin/blood , alpha 1-Antitrypsin/metabolism
3.
Psychiatr Q ; 88(4): 853-864, 2017 12.
Article in English | MEDLINE | ID: mdl-28229346

ABSTRACT

This study examined the association of subjective and objective community contextual factors with stigma of mental illness in a sample of users of community mental health services centers in South Korea. Five hundred thirty-two persons with MI were surveyed on perceived stigma and experienced stigma, and on two subjective measures of community characteristics-perceived disorder and perceived collective efficacy of their neighborhood. Objective community indicators at the neighborhood level were collected from a government administrative data base. Multilevel statistical analysis was conducted to identify the effects of individual-level characteristics and community-level objective indicators on stigma. Perceived neighborhood disorder was associated with both perceived stigma and experienced stigma. Perceived collective efficacy was associated with perceived stigma but not experienced stigma. The proportion of persons with disabilities in the neighborhood, an objective community indicator, was associated with experienced stigma. Mental health practitioners and policy planners need to examine the relevance of neighborhood characteristics in the design of policy and practice interventions in order to enhance the social inclusion of persons with MI.


Subject(s)
Community Mental Health Services , Mental Disorders/psychology , Mentally Ill Persons/psychology , Residence Characteristics , Social Perception , Social Stigma , Adult , Female , Humans , Male , Middle Aged , Multilevel Analysis , Republic of Korea
4.
BMC Infect Dis ; 15: 49, 2015 Feb 06.
Article in English | MEDLINE | ID: mdl-25656928

ABSTRACT

BACKGROUND: Plasmodium knowlesi was identified as the fifth major malaria parasite in humans. It presents severe clinical symptoms and leads to mortality as a result of hyperparasitemia in a short period of time. This study aimed to improve the current understanding of P. knowlesi and identify potential biomarkers for knowlesi malaria. METHODS: In the present study, we have employed two-dimensional gel electrophoresis-coupled immunoblotting techniques and mass spectrometry to identify novel circulating markers in sera from P. knowlesi-infected patients. Specifically, we have compared serum protein profiles from P. knowlesi-infected patients against those of healthy or P. vivax-infected individuals. RESULTS: We identified several immunoreactive proteins in malarial-infected subjects, including alpha-2-HS glycoprotein (AHSG), serotransferrin (TF), complement C3c (C3), hemopexin (HPX), zinc-2-alpha glycoprotein (ZAG1), apolipoprotein A1 (Apo-A1), haptoglobin (HAP), and alpha-1-B-glycoprotein (A1BG). However, only TF and HPX displayed enhanced antigenicity and specificity, suggesting that they might represent valid markers for detecting P. knowlesi infection. Additionally, six P. knowlesi-specific antigens were identified (K15, K16, K28, K29, K30, and K38). Moreover, although HAP antigenicity was observed during P. vivax infection, it was undetectable in P. knowlesi-infected subjects. CONCLUSIONS: We have demonstrated the application of immunoproteomics approach to identify potential candidate biomarkers for knowlesi malaria infection.


Subject(s)
Biomarkers/blood , Malaria/diagnosis , Plasmodium knowlesi/pathogenicity , Plasmodium vivax/pathogenicity , Adult , Antigens, Protozoan/blood , Electrophoresis, Gel, Two-Dimensional , Female , Humans , Malaria/blood , Malaria/parasitology , Malaysia , Male , Middle Aged , Plasmodium knowlesi/immunology , Plasmodium vivax/immunology , Sensitivity and Specificity
5.
J Ment Health ; 24(4): 183-8, 2015 Aug.
Article in English | MEDLINE | ID: mdl-26158793

ABSTRACT

BACKGROUND: Community integration is an important component of recovery for persons with serious mental illnesses (SMI). However, persons with SMI often experience barriers in using community resources, participating in community activities, and developing interactions with neighbors and other community members. AIMS: This study examines the association between different sources of social support, including family, friends and mental health services providers, and three dimensions of community integration. METHOD: A sample of 399 persons with SMI was interviewed from community-based mental health service agencies in South Korea. RESULTS: Family support and friendship support positively influenced all three aspects of community integration. More support from mental health professionals was associated with increased perceived accessibility to community resources but decreased involvement in community activities. CONCLUSION: Recommendations are made in supporting the role of natural networks and in advocating for a consumer-centered approach to service delivery.


Subject(s)
Community Integration/psychology , Mental Disorders/psychology , Social Support , Adult , Community Mental Health Services , Family/psychology , Female , Friends/psychology , Health Personnel/psychology , Humans , Male , Republic of Korea
6.
Psychiatr Q ; 85(4): 453-65, 2014 Dec.
Article in English | MEDLINE | ID: mdl-24951960

ABSTRACT

This study examined the effects of social network characteristics on physical health among people with serious mental illness using social transactions that are reciprocal, and the combination of objective and subjective health measures. The sample consisted of a probability sample of 231 adults with serious mental illness who resided in permanent supportive housing in Philadelphia, Pennsylvania. Path analyses were conducted to examine the relationships between social network characteristics and two aspects of medical comorbidity, objective health and subjective health. Bivariate statistics showed that individuals with medical comorbidity were more likely to have contact with their network members and had a higher level of reciprocal positive tangible support when compared to those who did not have medical comorbidity. The results of the path analyses revealed that none of the social network characteristics were associated with better physical health. The lack of a significant relationship between social networks and better physical health is contrary to prior research findings. However, this is the first study to include both types of social transactions simultaneously as predictors of better physical health for individuals with serious mental illness. A longitudinal study would provide more insight into the temporal relationship of social networks and physical health conditions of people with serious mental illness. Furthermore, the transactional nature of social relationships, particularly for those with mental health issues, requires greater exploration.


Subject(s)
Mental Disorders/physiopathology , Mental Disorders/psychology , Social Support , Adult , Aged , Chi-Square Distribution , Comorbidity , Female , Humans , Male , Mental Disorders/diagnosis , Mental Disorders/epidemiology , Middle Aged , Retrospective Studies , Young Adult
7.
Psychiatr Rehabil J ; 35(4): 315-23, 2012.
Article in English | MEDLINE | ID: mdl-22491371

ABSTRACT

OBJECTIVE: Persons with psychiatric disabilities are at greater risk for medical comorbidity, and prior research suggests these persons may underutilize health services. In response, this study examined the impact of engagement in psychiatric rehabilitation services, including case management, on utilization of general health services among persons with psychiatric disabilities engaged in supported housing, while controlling for demographic and clinical characteristics. METHODS: Poisson regression analyses were used to examine the impact of socio-demographic, clinical, and service characteristics on reported utilization of general health services in the past year. RESULTS: Findings indicated supported housing residents receiving case management coupled with weekly contact with residential support services visited a general health practitioner more frequently than those with less support services. CONCLUSIONS AND IMPLICATIONS: Study results suggest psychiatric rehabilitation services provided to persons in the context of safe and affordable housing may represent an important mechanism for enabling persons with psychiatric disorders to access needed medical care.


Subject(s)
Health Services Needs and Demand/statistics & numerical data , Housing , Persons with Mental Disabilities/rehabilitation , Social Support , Adult , Cross-Sectional Studies , Female , Humans , Independent Living , Male , Middle Aged , Persons with Mental Disabilities/statistics & numerical data , Philadelphia , Regression Analysis , Socioeconomic Factors
8.
Int J Soc Psychiatry ; 68(3): 610-618, 2022 May.
Article in English | MEDLINE | ID: mdl-33554704

ABSTRACT

BACKGROUND AND AIMS: The increasing prevalence of mental illness and low treatment rate presents a pressing public health issue in China. Pervasive stigma is a significant barrier to mental health recovery and community inclusion. In particular, stigmatizing or supportive attitudes held by healthcare providers could either perpetuate or mitigate self-stigma of people with mental illness. Moreover, mental health resources are unevenly distributed in China, with most of them concentrated in urban centers and provincial capitals. This study explores healthcare providers' attitudes toward mental illness and the challenges they faced at work in a rural Chinese county. METHOD: Four focus groups were conducted with 36 healthcare providers from a three-tier mental healthcare system in a rural county in southwestern China. Focus group discussions were recorded and transcribed verbatim. The team employed a conventional content analysis approach for data analysis. All transcripts were double-coded by three bilingual team members who are native Chinese speakers. Coding discrepancies were resolved by consensus. RESULTS: Healthcare providers recruited from the county, township, and village levels varied in educational background, professional qualification, and experience of working with people with mental illness. Five thematic categories identified across four groups include (1) barriers to mental healthcare delivery, (2) keys to mental health recovery, (3) providers' attitudes toward providing care, (4) providers' perception toward patients and family members, and (5) providers' perception of training needs. CONCLUSIONS: This is a unique study that included healthcare providers from a three-tier healthcare system. Findings signal the importance of understanding healthcare practitioners' experiences and views to inform the design of training initiatives in rural or low-resource communities.


Subject(s)
Mental Health Services , Rural Health Services , Attitude of Health Personnel , China , Health Personnel/psychology , Humans , Mental Health , Patient Care
9.
J Med Primatol ; 40(2): 120-8, 2011 Apr.
Article in English | MEDLINE | ID: mdl-21044092

ABSTRACT

BACKGROUND: While some recently transmitted HIV clade C (HIV-C) strains exhibited tier 1 neutralization phenotypes, most were tier 2 strains (J Virol 2010; 84:1439). Because induction of neutralizing antibodies (nAbs) through vaccination against tier 2 viruses has proven difficult, we have generated a tier 1, clade C simian-human immunodeficiency virus (SHIV-C) to permit efficacy testing of candidate AIDS vaccines against tier 1 viruses. METHODS: SHIV-1157ipEL was created by swapping env of a late-stage virus with that of a tier 1, early form. RESULTS: After adaptation to rhesus macaques (RM), passaged SHIV-1157ipEL-p replicated vigorously in vitro and in vivo while maintaining R5 tropism. The virus was reproducibly transmissible intrarectally. Phylogenetically, SHIV-1157ipEL-p Env clustered with HIV-C sequences. All RM chronically infected with SHIV-1157ipEL-p developed high nAb titers against autologous as well as heterologous tier 1 strains. CONCLUSIONS: SHIV-1157ipEL-p was reproducibly transmitted in RM, induced cross-clade nAbs, and represents a tool to evaluate anti-HIV-C nAb responses in primates.


Subject(s)
AIDS Vaccines/immunology , HIV-1/immunology , Macaca mulatta/virology , Simian Immunodeficiency Virus/immunology , AIDS Vaccines/genetics , Animals , Antibodies, Neutralizing/immunology , CD4-Positive T-Lymphocytes/immunology , Disease Models, Animal , Genes, env , HIV-1/genetics , Macaca mulatta/immunology , Phylogeny , Reverse Transcriptase Polymerase Chain Reaction , Simian Acquired Immunodeficiency Syndrome/immunology , Simian Acquired Immunodeficiency Syndrome/prevention & control , Simian Immunodeficiency Virus/genetics
10.
PeerJ ; 9: e11548, 2021.
Article in English | MEDLINE | ID: mdl-34178453

ABSTRACT

BACKGROUND: Oral squamous cell carcinoma (OSCC) has increased in incidence from 1990 to 2017, especially in South and Southeast Asia. It is often diagnosed at an advanced stage with a poor prognosis. Therefore, early detection of OSCC is essential to improve the prognosis of OSCC. This study aims to identify the differentially expressed serum proteins as potential biomarkers for oral squamous cell carcinoma (OSCC). METHODS: Comparative proteomics profiling of serum samples from OSCC patients, oral potentially malignant disorder (OPMD) patients, and healthy individuals were performed using two-dimensional gel electrophoresis (2-DE) coupled with mass spectrometry (MS) (n = 60) and bioinformatics analysis. The enzyme-linked immunosorbent assay (ELISA) (n = 120) and immunohistochemistry (IHC) (n = 70) were used to confirm our findings. RESULTS: The 2-DE analysis revealed that 20 differentially expressed proteins were detected in OPMD and OSCC (p < 0.05). Bioinformatics analysis indicated that the activation of classical complement, liver X receptor/retinoid X receptor (LXR/RXR) activation, and acute phase response signaling pathway are associated with the development and progression of OSCC. Most of the detected proteins are acute-phase proteins and were related to inflammation and immune responses, including apolipoprotein A-I (APOA1), complement C3 (C3), clusterin (CLU), and haptoglobin (HP). The expression levels of CLU and HP in ELISA are consistent with the findings from the 2-DE analysis, except for the mean serum level of HP in OPMD, whereby it was slightly higher than that in control. IHC results demonstrated that CLU and HP are significantly decreased in OSCC tissues. CONCLUSION: Decreased expression of CLU and HP could serve as complementary biomarkers of OSCC. These proteins may assist in predicting the outcomes of OSCC patients. However, a larger cohort is needed for further investigation.

11.
Int J Soc Psychiatry ; 67(7): 935-945, 2021 Nov.
Article in English | MEDLINE | ID: mdl-33231134

ABSTRACT

BACKGROUND: Although knowledge is a crucial component in contact theory delineating how prejudice changes toward out-groups with stigmatized conditions, little is known about the mediating role of knowledge on contact, stigmatizing attitudes, and behaviors toward mental illness. AIM: This study aimed to examine the mechanism underlie contact and stigma change by knowledge. METHODS: A total of 366 participants including family members (FM), mental health providers (MHP), and community residents (CR) recruited across communities in Hong Kong and completed measures of contact level, contact quantity, contact quality, mental health related knowledge, prejudice, and discriminatory behaviors. Structural equation modeling was adopted to test the association among the key variables. RESULTS: Higher level of contact was significantly correlated with better knowledge, less prejudice, and less discriminatory behaviors. Knowledge was directly and negatively correlated with prejudicial attitudes but was not significantly related to discriminatory behaviors. Furthermore, lower levels of prejudice were associated with less discriminatory behaviors. CONCLUSION: Enhancement of contact may increase understanding toward people with mental illness (PMI) and diminish stigmatizing attitudes and behaviors. Although prejudicial attitudes may be reduced by broadening mental health knowledge, increasing knowledge only might not ameliorate discriminatory behaviors. Future research should test mediators on contact and stigma by using longitudinal data.


Subject(s)
Mental Disorders , Social Stigma , Hong Kong , Humans , Mental Health , Prejudice
12.
Int J Soc Psychiatry ; 67(6): 622-631, 2021 Sep.
Article in English | MEDLINE | ID: mdl-33059491

ABSTRACT

BACKGROUND: Self-stigma exerts a range of adversities for persons with severe mental illness (SMI), however, little is known about the association between peer contact, social support and self-stigma. AIMS: This study aimed to explore the mediating role of social support on the relationship between peer contact and self-stigma among persons with SMI in Hong Kong. METHODS: A total of 159 persons with SMI (schizophrenia and mood disorder) in community service centres participated in the study through completing a survey on self-stigma, social functioning, social support, perception of peer contact and mass media. Logistic regression was utilised to explore the influencing factors of self-stigma among the participants. RESULTS: The results showed that 81.1% of participants reported moderate to severe levels of self-stigma. Self-stigma was significantly associated with diverse factors (e.g. social functioning). Importantly, positive peer contact was significantly associated with lower self-stigma of persons with SMI. Social support acted as a mediator between peer contact and self-stigma. CONCLUSION: The results of this study suggest that contact-based interventions, such as enhancing positive peer-to-peer contact, should be conducted for reducing self-stigma among persons with SMI.


Subject(s)
Mental Disorders , Social Stigma , Hong Kong , Humans , Self Concept , Social Support
13.
Qual Health Res ; 20(5): 654-67, 2010 May.
Article in English | MEDLINE | ID: mdl-20154301

ABSTRACT

In this article we describe a focus group study of the perspectives of diverse groups of mental health consumers on the concept of community. We identify the core domains that constitute the notion of community, and commonalities and differences in the perception of community along the lines of ethnicity and sexual orientation/gender identity. Seven focus groups were conducted with a total of 62 participants. Transcripts were analyzed using the grounded theory approach.Two domains-togetherness and community acceptance-emerged as common to four types of communities that were most frequently mentioned in the focus group discussion. Our findings show that identities other than those associated with mental illness and the role of service user are critical to the understanding of the psychological sense of community among persons with psychiatric disabilities. We suggest that mental health providers empower consumers to expand their "personal communities" beyond that of mental health clients using their diverse identities, and design interventions for addressing the stigma emanating from identities that are discriminated against by the wider society.


Subject(s)
Mental Disorders , Patients/psychology , Social Adjustment , Adult , Aged , Focus Groups , Humans , Mental Disorders/ethnology , Middle Aged , Sexuality , Social Identification , Stereotyping , Surveys and Questionnaires
14.
J Immigr Minor Health ; 22(5): 888-894, 2020 Oct.
Article in English | MEDLINE | ID: mdl-32519152

ABSTRACT

Face-saving represents a unique culturally salient construct among Chinese. However, our understanding regarding its relationship with psychological distress in this population remains limited. The objective of this cross-sectional study is to examine (1) the relationship between face-saving and depressive symptoms among U.S. Chinese older adults; and (2) whether face-saving mediates the relationship between acculturation and depressive symptoms. Data were from the Population Study of Chinese Elderly in Chicago (N = 3132), the largest epidemiologic study of Chinese older adults in Western countries. The relationship between face-saving and self-reported depressive symptoms was investigated by step-wise multivariable linear regression models. The Sobel test was used to test the mediating effect of face-saving. U.S. Chinese older adults with higher face-saving values experienced greater levels of depressive symptoms (B = 0.05, p < 0.001) than those with lower face-saving values, even after sociodemographic factors, health characteristics, and social support were accounted for. The mediation effect of face-saving was not statistically significant. The study findings underscore the significance of a unique cultural factor, specifically face-saving, in understanding U.S. Chinese older adults' experience of depressive symptoms. Depression screening and treatment programs should pay attention to face-saving issues among U.S. Chinese older adults. Future studies need to incorporate cultural factors in mental health research in diverse populations.


Subject(s)
Asian , Depression , Aged , China/epidemiology , Cross-Sectional Studies , Depression/epidemiology , Humans , Risk Factors
15.
Front Psychiatry ; 11: 487, 2020.
Article in English | MEDLINE | ID: mdl-32581869

ABSTRACT

OBJECTIVE: Our study aimed to examine psychiatric diagnoses and treatment preceding a schizophrenia diagnosis in adolescents, stratified by sex and race/ethnicity. METHODS: Using Medicaid physical and behavioral health and pharmacy claims data, we identified 1,459 adolescents who were aged 9-17 years and diagnosed with schizophrenia between January 2006 through June 2009. Psychiatric diagnosis, mental health service use including psychiatric hospitalization, residential treatment and outpatient therapy and psychotropic medication use preceding schizophrenia were identified. RESULTS: Forty-five percent of the adolescents were diagnosed with one or more psychiatric conditions. More than 40% of the adolescents were hospitalized or placed in a residential treatment facility for other psychiatric conditions preceding schizophrenia. Overall, 72% of the adolescents were prescribed with one or more psychotropic medications and 22% were prescribed with three or more psychotropic medications in the year prior to their first schizophrenia diagnosis. We found that sex and race/ethnicity influence preceding psychiatric conditions and psychiatric treatment use. CONCLUSIONS: Careful screening and evaluation to validate diagnoses is important as the presence of certain psychiatric morbidity is common among adolescents with schizophrenia during the prodromal period. Developing acceptable and accessible interventions that will reduce psychiatric hospitalization and residential treatment care and improve care connection for schizophrenia treatment is important to mitigate complexity in treatment for adolescents and reduce cost burden for families and the society. Integrating health claims data in the development of schizophrenia risk conversion models can be useful in effectively predicting ideal timing of tailored interventions for adolescents with preceding psychiatric conditions.

16.
Soc Sci Med ; 68(8): 1376-87, 2009 Apr.
Article in English | MEDLINE | ID: mdl-19251346

ABSTRACT

Housing and services for persons with developmental disabilities (DD) have been shaped by the normalization approach, a commitment to full integration within the general community. In contrast, housing and services for persons with psychiatric disabilities (PD) have had various and sometimes conflicting goals, including provision of custodial care, promotion of therapeutic community, and community integration. This cross-field study compares the neighborhood characteristics of publicly-funded housing for the PD and DD populations in a metropolitan community. The aim of the study was to examine whether the contrasting housing approaches are reflected at an ecological level and to consider how these findings relate to the goal of community integration for people with PD and DD. Administrative databases provided residential addresses of 1932 residents with PD living in 297 locations and 1716 residents with DD living in 749 locations in the city of Philadelphia. The 2000 U.S. Census and city's police department database provided information on neighborhood characteristics. Geographic information system (GIS) methodology generated maps displaying the distribution of housing locations in relation to spatial dispersion, distress, stability, safety, and race/ethnic diversity. Statistical analyses compared neighborhood characteristics of the DD and PD populations. Findings indicated that the DD population in supportive housing was more spatially dispersed, and lived in less distressed, less unstable, more secure, but equally racially/ethnically diverse neighborhoods when compared to the PD population in supportive housing. Greater geographic dispersal among persons with DD may be the result of more emphasis on normalization within policies and programs determining the location of their housing. The higher funding levels for housing and residential support for persons with DD also provided programs with the option of placing people in higher income neighborhoods. Given that community integration has emerged as an organizing principle within mental health services over other models, policymakers in the field of psychiatric disabilities may have much to learn from the normalization movement for people with developmental disabilities.


Subject(s)
Developmental Disabilities , Disabled Persons , Residence Characteristics , Residential Facilities/organization & administration , Adolescent , Adult , Databases, Factual , Female , Humans , Male , Models, Organizational , Models, Statistical , Pennsylvania , Persons with Mental Disabilities
17.
J Immigr Minor Health ; 21(5): 938-945, 2019 Oct.
Article in English | MEDLINE | ID: mdl-30302622

ABSTRACT

Older adults visit emergency departments (EDs) at a disproportionally higher rate than other age groups. Prior studies examining racial disparities in ED utilization focus on African Americans and Hispanics. There is a dearth of information on ED utilization patterns among older Asian Americans despite the evidence that ED expenditures in Asian Americans are comparable to that of Caucasians. To address this knowledge gap, we examined factors associated with ED service utilization in the largest Asian subgroup, U.S. Chinese older adults. Cross-sectional data from the Population Study of Chinese Elderly in Chicago (PINE) (N = 3,157) were used. Multivariate negative binomial regression analyses were conducted to examine significant factors associated with ED use. Higher education (rate ratio [RR] = 1.03, 95% confidence interval [CI] 1.00-1.05) and acculturation levels (RR = 1.02, CI 1.00-1.04), fewer people in the household (RR = 0.94, CI 0.88-0.99), health insurance coverage (RR = 1.34, CI 1.01-1.78), lower income (RR = 0.89, CI 0.80-0.99), poorer perceived health (RR = 0.67, CI 0.58-0.77), more functional limitations (RR = 1.09, CI 1.06-1.13) and depressive symptoms (RR = 1.04, CI 1.02-1.07), and a history of heart disease (RR = 2.28, CI 1.83-2.84), stroke (RR = 1.68, CI 1.20-2.35), cancer (RR = 1.86, CI 1.31-2.63), and hip fracture (RR = 1.42, CI 1.02-1.98) were associated with higher rates of ED visits. Our findings highlight several significant correlates of ED use in U.S. Chinese older adults. Culturally-appropriate interventions modifying these factors have the potential to decrease ED visits and improve care outcomes in this population.


Subject(s)
Asian People , Asian , Emergency Service, Hospital , Patient Acceptance of Health Care , Acculturation , Aged , Aged, 80 and over , Chicago , Cross-Sectional Studies , Female , Humans , Male , Middle Aged , Patient Acceptance of Health Care/statistics & numerical data , United States
18.
Res Dev Disabil ; 83: 108-119, 2018 Dec.
Article in English | MEDLINE | ID: mdl-30193159

ABSTRACT

PURPOSE: This study examines the locational patterns of publicly-funded supportive housing for people with intellectual disability (people with ID) and people with psychiatric disorders (people with PD). METHODS: Administrative data provided housing locations of 4599 people with ID and people with PD in one urban county and one suburban county in the United States. Census tract data captured neighborhood characteristics. Descriptive statistics and spatial analysis were used to analyze the distribution of supportive housing sites. RESULTS: People with ID were more dispersed across a larger number of census tracts with smaller number of residents per tract than people with PD. While spatial dispersion in favor of people with ID was consistent across both counties, difference in dispersion was more pronounced in the urban county. People with PD were concentrated in neighborhoods with more socio-economic disadvantage, more residential instability, and a higher level of race/ethnic diversity than people with ID. CONCLUSION: This study suggests that spatial-analytic method can serve as a useful tool for assessing the extent to which integrated housing is achieved for people with ID and people with PD. Interpretation of findings should be given due consideration of the policy context and neighborhood characteristics of the study communities.


Subject(s)
Intellectual Disability , Mental Disorders , Public Housing , Residence Characteristics/statistics & numerical data , Adult , Female , Humans , Intellectual Disability/epidemiology , Intellectual Disability/psychology , Intellectual Disability/rehabilitation , Male , Mental Disorders/epidemiology , Mental Disorders/psychology , Mental Disorders/rehabilitation , Psychiatric Rehabilitation/methods , Public Housing/organization & administration , Public Housing/statistics & numerical data , Socioeconomic Factors , Spatial Analysis , Suburban Health/statistics & numerical data , United States/epidemiology , Urban Health/statistics & numerical data
19.
Int J Ment Health Syst ; 12: 14, 2018.
Article in English | MEDLINE | ID: mdl-29636792

ABSTRACT

BACKGROUND: It is estimated that 8 million of the Chinese adult population had a diagnosis of schizophrenia. Stigma associated with mental illness, which is pervasive in the Chinese cultural context, impacts both persons with schizophrenia and their family caregivers. However, a review of the literature found a dearth of research that explored internalized stigma from the perspectives of both patients and their caregivers. METHODS: We integrated data from standardized scales and narratives from semi-structured interviews obtained from eight family-dyads. Interview narratives about stigma were analyzed using directed content analysis and compared with responses from Chinese versions of the Internalized Stigma of Mental Illness Scale and Affiliated Stigma Scale. Scores from the two scales and number of text fragments were compared to identify consistency of responses using the two methods. Profiles from three family-dyads were analyzed to highlight the interactive aspect of stigma in a dyadic relationship. RESULTS: Our analyses suggested that persons with schizophrenia and their caregivers both internalized negative valuation from their social networks and reduced engagement in the community. Participants with schizophrenia expressed a sense of shame and inferiority, spoke about being a burden to their family, and expressed self-disappointment as a result of having a psychiatric diagnosis. Caregivers expressed high level of emotional distress because of mental illness in the family. Family dyads varied in the extent that internalized stigma were experienced by patients and caregivers. CONCLUSIONS: Family plays a central role in caring for persons with mental illness in China. Given the increasingly community-based nature of mental health services delivery, understanding internalized stigma as a family unit is important to guide the development of cultural-informed treatments. This pilot study provides a method that can be used to collect data that take into consideration the cultural nuances of Chinese societies.

20.
J Behav Health Serv Res ; 34(2): 151-67, 2007 Apr.
Article in English | MEDLINE | ID: mdl-17357851

ABSTRACT

This study examined the patterns and correlates of group and organizational involvement among persons with psychiatric disabilities using a cross-sectional, probability sample of 252 residents in supported independent housing (SIH). Groups and organizations were classified according to whether or not they have a behavioral health focus. Demographic, clinical, and service use characteristics were examined as potential predictors of membership using Poisson regression models. Findings indicated that 60% of the sample was involved in some kind of behavioral or nonbehavioral health organization. Similar to the findings from the general population, higher rates of membership were found among older persons, Blacks, those with more years of education, and those with higher incomes. Other correlates specific to the SIH sample included prior homelessness, perceived discrimination, substance abuse history, psychiatric symptoms, psychiatric diagnosis, and contact with service providers. Implications of study findings for developing intervention strategies to enhance organizational membership and for future research are discussed.


Subject(s)
Housing , Mental Disorders/rehabilitation , Mental Health Services/statistics & numerical data , Social Support , Adolescent , Adult , Female , Health Status , Humans , Male , Mental Disorders/ethnology , Mental Disorders/psychology , Middle Aged , Philadelphia , Regression Analysis , Rehabilitation Centers , Socioeconomic Factors
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