1.
Org Lett
; 24(29): 5386-5390, 2022 Jul 29.
Article
in English
| MEDLINE
| ID: mdl-35856849
ABSTRACT
A Ni-catalyzed reductive arylalkenylation of alkynes with 1-bromo-2-(2-chlorovinyl)arenes in the presence of zinc powder has been developed. This base-free cyclization provides a novel protocol for the selective synthesis of 2-trifluoromethyl naphthalenes and ethyl 2-naphthoates from simple starting materials in moderate to good yields with excellent tolerance of functional groups.