Laparoscopic gastrectomy versus open gastrectomy for elderly patients with gastric cancer: a systematic review and meta-analysis.

BACKGROUND: The objective of this study was to evaluate the feasibility, safety, and potential benefits of laparoscopic gastrectomy (LG) comparing with open gastrectomy (OG) in elderly population. METHODS: Studies comparing LG with OG for elderly population with gastric cancer, published between January 1994 and July 2015, were identified in the PubMed, Embase, and ISI Web of Science databases. Operative outcomes (intraoperative blood loss, operative time, and the number of lymph nodes harvested) and postoperative outcomes (time to first ambulation, time to first flatus, time to first oral intake, postoperative hospital stay, postoperative morbidity) were included and analyzed. The Newcastle-Ottawa Scale was used to assess the quality of the pooled study. A funnel plot was used to evaluate the publication bias. RESULTS: Seven studies totaling 845 patients were included in the meta-analysis. LG in comparison to OG showed less intraoperative blood loss (weighted mean difference (WMD) -127.47; 95% confidence interval (CI) -202.79 to -52.16; P < 0.01), earlier time to first ambulation (WMD -2.07; 95% CI -2.84 to -1.30; P < 0.01), first flatus (WMD -1.04; 95% CI -1.45 to -0.63; P < 0.01), and oral intake (WMD -0.94; 95% CI -1.11 to -0.77; P < 0.01), postoperative hospital stay (WMD -5.26; 95% CI -7.58 to -2.93; P < 0.01), lower overall postoperative complication rate (odd ratio (OR) 0.39; 95% CI 0.28 to 0.55; P < 0.01), less surgical complications (OR 0.47; 95% CI 0.32 to 0.69; P < 0.01), medical complication (OR 0.35; 95% CI 0.22 to 0.56; P < 0.01), incisional complication (OR 0.40; 95% CI 0.19 to 0.85; P = 0.02), and pulmonary infection (OR 0.49; 95% CI 0.26 to 0.93; P = 0.03). No significant differences were observed between LG and OG for the number of harvested lymph nodes. However, LG had longer operative times (WMD 15.73; 95% CI 6.23 to 25.23; P < 0.01). CONCLUSIONS: LG is a feasible and safe approach for elderly patients with gastric cancer. Compared with OG, LG has less blood loss, faster postoperative recovery, and reduced postoperative morbidity.

A new feasible technique of mesh-reinforced pancreatojejunostomy and pancreatogastrostomy: retrospective analysis of 61 cases.

BACKGROUND: Pancreatic leak was the major concern after pancreatoduodenectomy. METHODS: A total of 61 patients who underwent mesh-reinforced pancreatojejunostomy or pancreatogastrostomy from August 2005 to November 2011 were retrospectively analyzed. RESULTS: The mean anastomosis time of mesh-reinforced pancreatojejunostomy was 25 minutes ranging from 22 to 35 minutes. In mesh-reinforced pancreatogastrostomy, the mean anastomosis time ranged from 20 to 38 minutes with an average of 30 minutes. Blood loss was 200 to 4,000 ml with an average of 710 ml in all patients. There was one case of pancreatic leak of Class A, three cases of pancreatic leak of Class B, one case of pancreatic leak of Class C, one case of choledochojejunostomy leakage, one case of gastrojejunostomy leakage, and three cases of abdominal bleeding. CONCLUSION: As a new technique, mesh-reinforced pancreatojejunostomy and pancreatogastrostomy might be a safe and feasible procedure to prevent postoperative pancreatic leak. TRIAL REGISTRATION: This research is waivered from trial registration because it was a retrospective analysis of medical records.

Comparison of Single-Person Laparoscopic Appendectomy Using a Novel Brace-Assisted Camera Holding System and Conventional Laparoscopic Appendectomy: A Neural Network Algorithm Analysis.

Background: Acute appendicitis represents one of the main causes of surgical emergencies. It can be approached as an open appendectomy or a laparoscopic appendectomy (LA). However, LA generally requires the cooperation of a surgeon and an assistant. This study aims to compare the safety and efficacy of the novel brace-assisted single-person laparoscopic appendectomy (BASPLA) with conventional laparoscopic appendectomy (CLA) in the treatment of patients diagnosed with acute appendicitis by neural network algorithm analysis. Methods: Between January 2020 and December 2021,a total of 120 adult patients with acute appendicitis were randomized to the BASPLA group (62 cases) and the CLA group (58 cases).The clinical data were compared between the two groups, including demographics, clinical characteristics, and outcomes. Results: There was no significant difference in patients' pain scores before operation (p = 0.68) and after operation (p = 0.81) and patient-reported cosmetic scores (p = 0.43) between the two groups. Operation time in the BASPLA group was longer than that in the CLA group (p<0.001). There were no significant differences in the conversion rate (p = 0.94), analgesics required before (p = 0.91) and after the operation (p = 0.78), intraoperative bleeding (p = 0.53), recovery of bowel movement time (p = 0.26), hospital stay (p = 0.06), and complication rate (p = 0.84) between the two groups. Conclusions: BASPLA for adult acute appendicitis can be a substitute for CLA, BASPLA is comparable to CLA in postoperative pain and quality of life. Compared to surgical assistants, it not only provides a stable, clear image for the surgeon but also frees up personnel. Especially in emergency surgery, it can achieve satisfactory clinical efficacy without requiring an assistant.

A new technique of mesh-reinforced pancreaticogastrostomy: report of 13 initial cases.

BACKGROUND: Pancreatic anastomotic leakage is a common problem after pancreaticoduodenectomy and is a leading cause of postoperative morbidity and mortality. It is important to establish a safe and simple technique of pancreatic-enteric anastomosis to minimize pancreatic leakage. PATIENTS AND METHODS: From July 2009 to February 2012, a new method of mesh-reinforced pancreaticogastrostomy was performed in 13 patients after completion of the pancreaticoduodenal resection. Patient demographic data, pathology of lesions, operative parameters, and postoperative outcomes were analyzed. RESULTS: The mean operative time was 6.9 hours (range, 5-11 hours), and the mean time for pancreaticogastrostomy was 25 minutes (range, 22-35 minutes). Intraoperative tests showed all pancreatic anastomoses were watertight. There was no postoperative death. No patient developed clinically significant pancreatic leakage (grade B or C) after operation; 1 patient (7.7%) was recognized to have a grade A pancreatic leakage. No significant complication (hemorrhage, intra-abdominal abscess, or cholangitis) was observed. The mean postoperative hospital stay was 20 days (range, 11-30 days). After discharge, all patients recovered well in the 4-week follow-up period without emergency room visit or re-admission. CONCLUSIONS: The mesh-reinforced pancreaticogastrostomy provides a new way to perform pancreatic-enteric drainage after pancreaticoduodenectomy and has the advantages of simplicity, ease of handling, and applicability to all types of pancreatic remnants.