Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 281
Filter
Add more filters

Publication year range
1.
Hemoglobin ; 48(1): 34-38, 2024 Jan.
Article in English | MEDLINE | ID: mdl-38192212

ABSTRACT

A pregnant woman living in Fujian Province, southeastern China, presented due to a risk of having a baby with ß-thalassemia major, during her second pregnancy, since she and her husband were suspected as ß-thalassemia carriers and their affected daughter was a transfusion-dependent patient. Using the common α-thalassemia and ß-thalassemia genotypes test, the pregnant woman was diagnosed as a ß-thalassemia carrier with ßIVS-2 - 654 (C→T)/ßN genotype and her daughter had a homozygosity for IVS - 2 - 654 (C→T) mutation, however, no abnormalities were detected in her husband. SMRT identified a Filipino ß0-deletion in her husband, and MLPA also revealed an unknown deletion in the HBB gene. Electrophoresis showed approximately 350 bp of the PCR product, and the ß-Filipino genotype presented novel fracture fragments ranging from 5,112,884 to 5,231,358 bp, and lacked a 118,475 bp fragment relative to the wild-type sequence. The daughter was therefore diagnosed with the ßIVS-2 - 654 (C→T)/ßFilipino genotype. Prenatal diagnosis with umbilical cord blood at 27th week of gestation showed heteroztgosity for IVS - 2 - 654 (C→T) mutation in the fetus and continued pregnancy was recommended. In conclusion, we identified the Filipino ß0-deletion in a Chinese family, from Fujian area, for the first time, during prenatal screening.


Subject(s)
alpha-Thalassemia , beta-Thalassemia , Pregnancy , Female , Humans , beta-Thalassemia/diagnosis , beta-Thalassemia/genetics , Genotype , Prenatal Diagnosis , Mutation , alpha-Thalassemia/genetics , China
2.
Int J Psychol ; 59(4): 568-577, 2024 Aug.
Article in English | MEDLINE | ID: mdl-38320969

ABSTRACT

This study examined whether Filipino mothers' and fathers' cultural values, namely individualism, collectivism and conformity values; are associated with parental warmth, rules/limit-setting and expectations of family obligations; and child internalising and externalising behaviours. Children (n = 103; Mage = 10.52, SDage = .44) and their mothers (n = 100) and fathers (n = 79) from urban Metro Manila, Philippines, responded to self-report measures orally or in writing. Mothers' collectivistic values, and fathers' individualistic and collectivistic values, were positively associated with expectations for children's familial obligations. Fathers' individualist values predicted lower internalising behaviours in children, whereas the valuing of conformity predicted greater paternal warmth. Future research on cultural values should unpack their dynamic meanings, processes and associations with parenting behaviours and child adjustment.


Subject(s)
Parenting , Social Values , Humans , Philippines/ethnology , Parenting/psychology , Parenting/ethnology , Female , Male , Child , Adult , Adolescent , Social Adjustment , Parent-Child Relations/ethnology
3.
Qual Life Res ; 32(8): 2271-2279, 2023 Aug.
Article in English | MEDLINE | ID: mdl-36952074

ABSTRACT

PURPOSE: This study aimed to describe the quality of life (QOL) and psychological distress (anxiety and depression) of Filipino patients with advanced solid cancers and identify sociodemographic and clinical-related factors associated with them. METHODS: 195 patients with advanced cancer were recruited from a major hospital treating cancer patients in the Philippines. Participants completed self-reported surveys on Quality-of-life (QOL-FACT-G) and psychological distress (HADS-D, HADS-A). Multi-variable OLS regression models were performed where sociodemographic, health history and clinical characteristics were included as predictors. RESULTS: The average total FACT-G score was 65.39/108 (Standard deviation (SD) = 13.76), with the physical well-being scale having the lowest scores (M = 14.14/28, SD = 5.92). The two most common symptoms reported were fatigue (88%) and pain (86.5%). Physical symptom burden was significantly negatively associated with QOL and psychological distress. The average HADS-total score was 14.46/21 (SD = 5.77), with 8% with probable anxiety and 27% with probable depression. Participants who reported greater reliance on their spiritual faith for strength in coping with illness reported lower depression scores. CONCLUSIONS: Our findings underline the importance of understanding the multi-dimensional outcomes of Filipino advanced cancer patients. Results may be used to improve QOL and reduce the psychological distress of advanced cancer patients.


Subject(s)
Neoplasms , Psychological Distress , Humans , Quality of Life/psychology , Philippines , Neoplasms/psychology , Adaptation, Psychological , Anxiety/psychology , Depression/therapy , Surveys and Questionnaires
4.
BMC Womens Health ; 23(1): 149, 2023 03 30.
Article in English | MEDLINE | ID: mdl-36997917

ABSTRACT

OBJECTIVES: This study assessed the CVD risk factors among Filipino women (FW) in Korea and compared them with FW in the Philippines and women in Korea (KW). METHODS: A cohort of 504 women from the Filipino Women's Health and Diet Study (FiLWHEL) aged 20-57 years old were age-matched (1:1 ratio) with women from the 2013 National Nutrition Survey in the Philippines and the 2013-2015 Korean National Health and Nutrition Examination Survey. Anthropometric data, blood pressure (BP), lipid and glucose levels were compared across the four populations by calculating the odds ratio (OR)s and 95% confidence interval (CI)s using conditional logistic regression models. RESULTS: Compared to KW, FW in Korea and FW in the Philippines were more than 2 and 3 times higher odds of having obesity for BMI ≥ 30 kg/m2 and waist circumference ≥ 88 cm, respectively. However, FW in Korea had the highest odds (OR 5.51, 95% CI 3.18-9.56) of having hypertension compared to KW. FW in the Philippines had the highest odds of having dyslipidemia (compared to KW, total cholesterol ≥ 200 mg/dL: OR 8.83, 95% CI 5.30-14.71; LDL-C ≥ 130 mg/dL: OR 3.25, 95% CI 2.13-4.98; and triglyceride ≥ 150 mg/dL: OR 2.59, 95% CI 1.59-4.22), but FW in Korea and KW had similar prevalence of dyslipidemia. CONCLUSIONS: FW in Korea had higher prevalence of obesity and hypertension, with similar prevalence of dyslipidemia compared to KW in this sample. FW in the Philippines had higher prevalence of dyslipidemia compared to FW in Korea. Further prospective studies are warranted to examine the CVD risk factors among continental and native-born Filipino women.


Subject(s)
Cardiovascular Diseases , Dyslipidemias , Hypertension , Humans , Young Adult , Adult , Middle Aged , Cardiovascular Diseases/epidemiology , Cardiovascular Diseases/etiology , Nutrition Surveys , Risk Factors , Obesity/epidemiology , Obesity/complications , Hypertension/epidemiology , Hypertension/complications , Dyslipidemias/epidemiology , Dyslipidemias/complications , Prevalence , Republic of Korea/epidemiology
5.
BMC Public Health ; 23(1): 885, 2023 05 15.
Article in English | MEDLINE | ID: mdl-37189145

ABSTRACT

BACKGROUND: Cardiovascular disease (CVD) remains the leading cause of death in the US. CVD incidence is influenced by many demographic, clinical, cultural, and psychosocial factors, including race and ethnicity. Despite recent research, there remain limitations on understanding CVD health among Asians and Pacific Islanders (APIs), particularly some subgroups and multi-racial populations. Combining diverse API populations into one study group and difficulties in defining API subpopulations and multi-race individuals have hampered efforts to identify and address health disparities in these growing populations. METHODS: The study cohort was comprised of all adult patients at Kaiser Permanente Hawai'i and Palo Alto Medical Foundation in California during 2014-2018 (n = 684,363). EHR-recorded ICD-9 and ICD-10 diagnosis codes were used to indicate coronary heart disease (CHD), stroke, peripheral vascular disease (PVD), and overall CVD. Self-reported race and ethnicity data were used to construct 12 mutually exclusive single and multi-race groups, and a Non-Hispanic White (NHW) comparison group. Logistic regression models were used to derive prevalence estimates, odds ratios, and confidence intervals for the 12 race/ethnicity groups. RESULTS: The prevalence of CHD and PVD varied 4-fold and stroke and overall CVD prevalence varied 3-fold across API subpopulations. Among Asians, the Filipino subgroup had the highest prevalence of all three CVD conditions and overall CVD. Chinese people had the lowest prevalence of CHD, PVD and overall CVD. In comparison to Native Hawaiians, Other Pacific Islanders had significantly higher prevalence of CHD. For the multi-race groups that included Native Hawaiians and Other Pacific Islanders, the prevalence of overall CVD was significantly higher than that for either single-race Native Hawaiians or Other Pacific Islanders. The multi-race Asian + White group had significantly higher overall CVD prevalence than both the NHW group and the highest Asian subgroup (Filipinos). CONCLUSIONS: Study findings revealed significant differences in overall CVD, CHD, stroke, and PVD among API subgroups. In addition to elevated risk among Filipino, Native Hawaiian, and Other Pacific Islander groups, the study identified particularly elevated risk among multi-race API groups. Differences in disease prevalence are likely mirrored in other cardiometabolic conditions, supporting the need to disaggregate API subgroups in health research.


Subject(s)
Cardiovascular Diseases , Native Hawaiian or Other Pacific Islander , Pacific Island People , Adult , Humans , California/epidemiology , Cardiovascular Diseases/epidemiology , Hawaii/epidemiology , Prevalence , Asian , Population Groups/ethnology
6.
J Adv Nurs ; 79(7): 2684-2694, 2023 Jul.
Article in English | MEDLINE | ID: mdl-36908101

ABSTRACT

AIMS: In July 2022, the human monkeypox virus was declared by the World Health Organization, a public health emergency of global concern. This study investigated the Filipinos' knowledge of monkeypox and determined the demographic variables that predicted it. DESIGN: Correlational and cross-sectional design adhering to STROBE guidelines. METHODS: Participants were recruited conveniently through social media platforms (n = 575). This study used a 21-item monkeypox knowledge survey questionnaire to collect data from July to September 2022. Logistic regression analysis was used to analyse the data. RESULTS: Most participants (53.74%) were above 30 years old, females (68.87%), residing in Luzon (54.96%), college graduates (61.04%), Catholics (78.61%) and employed (68%). Social media, particularly Facebook (57.91%), is the common source of monkeypox-related information (78.61%). Participants' age (>30 years old) is the only predictor of monkeypox infection knowledge (aOR: 3.13; 95%CI: 1.25-7.87, p = .015). They are three times more likely to be knowledgeable than those under 30. CONCLUSION: The findings highlight the importance of evidence-based strategies for increasing public knowledge and awareness. The government, healthcare workers and the public should adopt proactive preventive measures against human monkeypox to prevent future pandemics. PATIENT OR PUBLIC CONTRIBUTION: No patient or public contribution has been made in this study. IMPACT STATEMENT: What problem did the study address? Assessing people's knowledge about monkeypox will help the government and healthcare workers (HCWs) create policies to prevent the spread of the virus. To the best of my knowledge, this is the first study that used a national online survey to assess Filipinos' human monkeypox knowledge. What were the main findings? Most participants had insufficient knowledge of the monkeypox infection. Participants' primary source of monkeypox infection information is social media, specifically Facebook. Participants older than 30 had higher knowledge of monkeypox infection. Where and on whom will the research have impact? Raising public awareness and knowledge about monkeypox disease prevents viral transmission in the community. HCWs (e.g., nurses, midwives, and doctors) should report monkeypox patients to appropriate health authorities. Standard and droplet precautions should be practiced and taught to the public to prevent the virus' spread. The government and HCWs should intensify monkeypox awareness programs to increase the public's knowledge and awareness of the disease. They can utilize social media platforms to disseminate correct and relevant information.


Subject(s)
COVID-19 , Mpox (monkeypox) , Female , Humans , Adult , Cross-Sectional Studies , SARS-CoV-2 , Philippines
7.
Psychol Health Med ; 28(6): 1399-1410, 2023 Jul.
Article in English | MEDLINE | ID: mdl-35635265

ABSTRACT

This research explored the association of perceptions of gratitude and kindness at work with well-being outcomes, such as relatedness needs satisfaction, life satisfaction, and COVID-19 anxiety among selected Filipino employees during the COVID-19 pandemic. Hierarchical regression analyses demonstrated that kindness positively predicted relatedness needs satisfaction even after controlling for participants' age, gender, employment status, and length of stay in the organization. Gratitude positively predicted life satisfaction. This research underscores the mental health payoffs associated with fostering gratitude and kindness in organizational contexts during the COVID-19 pandemic.


Subject(s)
COVID-19 , Humans , COVID-19/epidemiology , Pandemics , Anxiety/epidemiology , Employment/psychology , Outcome Assessment, Health Care
8.
Child Psychiatry Hum Dev ; 54(4): 1075-1084, 2023 Aug.
Article in English | MEDLINE | ID: mdl-35076896

ABSTRACT

Prior research has demonstrated the role of kind school climate in students' academic and social-emotional learning outcomes. However, there is sparse literature showing the link of school kindness to mental health functioning. This study examines the association of school kindness with well-being dimensions such as positive emotions and depressive symptoms among 1287 Filipino high school students. It also explored whether school kindness would have indirect effects on well-being via school belongingness. Structural equation modeling via maximum likelihood estimation approach showed that school kindness was linked to higher positive emotions and lower depressive symptoms after controlling for demographic covariates such as age and gender. Further, results of bias-corrected bootstrapping analyses demonstrated that school kindness had indirect effects on positive emotions and depressive symptoms via school belongingness. This research underscores the mental health benefits associated with fostering kindness in school contexts.


Subject(s)
Mental Health , Schools , Humans , Students/psychology , Emotions
9.
Public Health Nurs ; 40(6): 836-843, 2023.
Article in English | MEDLINE | ID: mdl-37530122

ABSTRACT

OBJECTIVE/DESIGN: The University of Hawai'i Cancer Center works with academic and community partners to examine health disparities and inequities that persist among Pacific Island Populations through the Pacific Island Partnership for Cancer Health Equity (PIPCHE). The Partnership's Community Outreach Core (COC) assists and promotes cancer research and helps to ensure the integration of historically excluded community perspectives by utilizing community-engaged and culturally-grounded approaches to reduce cancer burdens. However, cancer health disparities among Filipinos demonstrate a need for cancer-control initiatives within this community. SAMPLE/MEASUREMENTS: COC staff conducted five semi-structured key informant interviews with Filipino nurse and healthcare leaders in Hawai'i to establishpartnerships with the community, as well as provide community-driven guidance for future cancer prevention and control efforts. RESULTS: The informants provided recommendations for COC community engagement, relationship building, and future areas of directed cancer focus. The interviews also initiated relationship-building and community collaborations for directed cancer education and resources within Filipino communities. CONCLUSION: The themes uncovered from the interviews provided guidance on how to begin addressing cancer concerns, and led to the informants' subsequent membership in our Outreach Advisory Council to engage in future collaboration with the Filipino community and a framework for future community-engaged cancer prevention efforts.


Subject(s)
Community-Institutional Relations , Neoplasms , Humans , Hawaii , Health Education , Neoplasms/prevention & control , Delivery of Health Care
10.
Public Health Nurs ; 40(5): 621-628, 2023.
Article in English | MEDLINE | ID: mdl-37415444

ABSTRACT

OBJECTIVE: This research study aims to identify the fundamental components of community adaptation for a culturally tailored care partner activation program for Filipino American family caregivers of patients with Alzheimer's Disease and related dementia (ADRD). DESIGN: The study utilized focus group interviews with community nurse leaders, stakeholders, and family caregivers of patients with ADRD. RESULTS: The research revealed that education and knowledge about the disease, community-based services and facilities, support groups and resources, spiritual and cultural values, and access to transportation are all critical components for community adaptation. CONCLUSION: The findings suggest that a culturally tailored care partner activation program that incorporates these components can enhance the quality of life for Filipino American caregivers and their loved ones with ADRD. The nursing implications of the study underscore the importance of nurses being culturally competent and sensitive to the unique challenges faced by Filipino American caregivers. Nurses can provide valuable support to caregivers by educating them, connecting them with community resources, and advocating for culturally responsive care practices.


Subject(s)
Alzheimer Disease , Dementia , Humans , Caregivers , Quality of Life , Asian
11.
J Cross Cult Gerontol ; 38(1): 39-81, 2023 Mar.
Article in English | MEDLINE | ID: mdl-36622513

ABSTRACT

Drawing on international research, this article examines and navigates through the existing social gerontological and ethnogerontological literature to assess how Filipino aging is understood within Global North societies. A scoping review was conducted in 2018 and in 2022 to offer key insights into how Filipinos age in both the ancestral homeland and increasingly within Global North diasporas. While the existing literature on Filipino aging does mirror existing ethnogerontological literature, which heavily focuses on indicators of cognitive, physical and mental health, and access and provision to formal services, the Filipino-specific literature calls attention to emerging dynamics distinctly related to transnational aging, and renegotiated caring dynamics within intergenerational Filipino families and kinship networks. This paper considers a future research agenda of the growing realities for aging Filipino communities across Global North contexts.


Subject(s)
Aging , Human Migration , Humans , Mental Health , Southeast Asian People
12.
J Public Health (Oxf) ; 44(2): e295-e296, 2022 06 27.
Article in English | MEDLINE | ID: mdl-34131754

ABSTRACT

The coronavirus disease of 2019 pandemic has brought not only disaster to humanity but also the best in each human individual. Filipinos, in a special way, have exhibited the inherent greatness of the human person in the construction of the community pantries where people who can sustain their needs in time of pandemic would donate some provisions to those who are needy. The establishment of various community pantries across the Philippines embodies the spirituality of 'Alay Kapwa', a spirituality that connects people together especially in time of crisis to be persons for others rather than harboring an unnaturalistic human and primitive attitude of self-centeredness.


Subject(s)
Disasters , Spirituality , Asian People , Attitude , Humans , Pandemics
13.
J Public Health (Oxf) ; 44(4): e656-e657, 2022 12 01.
Article in English | MEDLINE | ID: mdl-34865176

ABSTRACT

BACKGROUND: Mental health problems are prevalent among medical frontliners, as demonstrated in the study by Ghaleb et al. in the case of the Eastern Mediterranean Region. As mental health can be strengthened by spirituality, this study probed into the spirituality of bahala na of overseas Filipino health care workers. METHODOLOGY: A phenomenological research was conducted that includes an interview of 17 Filipino Catholic migrant nurses in five countries, on the situations when they find themselves exclaiming "bahala na" in their work as frontliners, and what this means for them. RESULTS: Affirming the notion of bahala na as an expression of hopeful risk-taking, the study showed that the nurses usually exclaim bahala na when they have done everything in their power in a given situation and they are now leaving the rest to God. The spirituality of bahala na helped the nurses face the stresses brought about by the pandemic, and when tapped, can further aid them in fighting against institutional racism to promote health equity in the medical community.


Subject(s)
Spirituality , Transients and Migrants , Humans , Health Promotion , Pandemics , Risk-Taking
14.
BMC Public Health ; 22(1): 1954, 2022 10 22.
Article in English | MEDLINE | ID: mdl-36273116

ABSTRACT

BACKGROUND: Asian adults develop Type 2 diabetes at a lower body mass index (BMI) compared to other racial/ethnic groups. We examined the variation in prevalence of prediabetes and diabetes among Asian ethnic groups within weight strata by comparing middle-aged Chinese, Filipino, South Asian, and White adults receiving care in the same integrated healthcare delivery system. METHODS: Our retrospective cross-sectional U.S. study examined data from 283,110 (non-Hispanic) White, 33,263 Chinese, 38,766 Filipino, and 17,959 South Asian adults aged 45-64 years who were members of a Northern California health plan in 2016 and had measured height and weight. Prediabetes and diabetes were classified based on laboratory data, clinical diagnoses, or diabetes pharmacotherapy. Age-standardized prevalence of prediabetes and diabetes were compared by race/ethnicity within healthy weight, overweight, and obesity categories, using standard BMI thresholds for White adults (18.5 to < 25, 25 to < 30, ≥ 30 kg/m2) and lower BMI thresholds for Asian adults (18.5 to < 23, 23 to < 27.5, ≥ 27.5 kg/m2). Prevalence ratios (PRs) were used to compare the prevalence of diabetes and prediabetes for Asian groups to White adults in each weight category, adjusted for age and BMI. RESULTS: Across all weight categories, diabetes prevalence was higher for Asian than White adults, and among Asian groups it was highest for Filipino and South Asian adults. Compared to White, PRs for South Asian men/women at healthy BMI were 1.8/2.8 for prediabetes and 5.9/8.0 for diabetes, respectively. The PRs for Filipino men/women at healthy BMI were 1.8/2.6 for prediabetes and 5.0/7.5 for diabetes, respectively. For Chinese men/women at healthy BMI, the PRs for prediabetes (2.1/2.9) were similar to Filipino and South Asian, but the PRs for diabetes were lower (2.1/3.4). CONCLUSION: Chinese, Filipino, and South Asian adults have higher prevalence of prediabetes and diabetes than White adults in all weight categories, despite using lower BMI thresholds for weight classification in Asian groups. Within Asian ethnic groups, Filipino and South Asian adults had considerably higher diabetes prevalence than Chinese adults. Our data emphasize the disproportionate metabolic risk among middle-aged Asian adults and underscore the need for diabetes screening among high-risk Asian groups at healthy BMI levels.


Subject(s)
Diabetes Mellitus, Type 2 , Prediabetic State , Adult , Middle Aged , Female , Humans , Overweight/epidemiology , Ethnicity , Prediabetic State/epidemiology , Prevalence , Diabetes Mellitus, Type 2/epidemiology , Cross-Sectional Studies , Electronic Health Records , Retrospective Studies , Asian , Obesity/epidemiology , Body Mass Index
15.
BMC Public Health ; 22(1): 654, 2022 04 05.
Article in English | MEDLINE | ID: mdl-35382800

ABSTRACT

BACKGROUND: The dietary environment promoting adiposity keeps evolving and of interest is the significance of dietary branched-chain amino acids (BCAA). This study assessed the association between dietary BCAA intakes and odds of obesity among immigrant Filipino women in Korea. METHOD: We included 423 immigrant Filipino women enrolled in the Filipino Women's diet and health study in the Republic of Korea. Dietary BCAA intakes were estimated from 24 hour recalls and adjusted for energy intake using the residual method. General obesity was derived from direct anthropometric measurements (height, weight and waist circumference - WC) and defined as body mass index (BMI) ≥25 kg/m2 and abdominal obesity as WC ≥80 cm. Odds ratios (OR) and 95% confidence intervals (CI) by tertile distribution of energy-adjusted BCAA intakes were estimated using multivariable logistic regression with a two-sided P < 0.05. RESULTS: Median (interquartile range) for BCAA intakes in g/day were; 7.9 (5.8, 10.3) g/day for total BCAA; 2.0 (1.5, 2.6) g/day for isoleucine, 3.5(2.5, 4.6) g/day for leucine and 2.4 (1.8, 3.1) g/day for valine. Mean BMI and WC were 23.6 ± 3.8 kg/m2 and 79.8 ± 9.3 cm, respectively. Also, 30.2% (128) had BMI ≥25 kg/m2 and 42.0% (178) had WC ≥80 cm. ORs (95%CIs) of general obesity across tertile distribution of energy-adjusted total BCAA intakes were 1.00, 0.81 (0.47, 1.37) and 0.62 (0.36, 1.07; P for trend = 0.08). A similar trend was observed across tertile distribution of energy-adjusted isoleucine, leucine and valine intakes. However, there was a statistically significant inverse association between total BCAA intake and odds of general obesity in a subset of non-smokers; 1.00, 0.68 (0.39, 1.20) and 0.55 (0.31, 0.98; P for trend = 0.04). CONCLUSION: We found a suggestive inverse association between higher dietary BCAA intake and odds of obesity in this sample of immigrant Filipino women, particularly among non-smokers. Prospective cohort studies among the immigrant population will be necessary to verity these findings.


Subject(s)
Amino Acids, Branched-Chain , Emigrants and Immigrants , Diet , Humans , Obesity/epidemiology , Prospective Studies
16.
Int J Neurosci ; : 1-6, 2022 Aug 08.
Article in English | MEDLINE | ID: mdl-35722686

ABSTRACT

BACKGROUND: Apomorphine hydrochloride is used in the management of advanced Parkinson disease (PD), either as a rescue medication for off periods during levodopa therapy or as a maintenance pump medication. This is the first study to describe the effects of apomorphine in Filipino patients with PD. OBJECTIVE: To evaluate the safety and efficacy of apomorphine ampules (APO-go®) pump infusion in the treatment of motor fluctuations in patients inadequately controlled on oral anti-Parkinson medications. METHODS: Patients diagnosed with PD who developed motor fluctuations with levodopa were evaluated at baseline and at the end of the study using the Modified Hoehn and Yahr (H&Y) Scale, the Unified Parkinson's Disease Rating Scale (UPDRS) and the Abnormal Involuntary Movement Scale (AIMS). After initial assessment, patients were administered 20 ampules of apomorphine hydrochloride 10 mg/mL by infusion pump over 20 days. Intention-to-treat (ITT) analysis included all patients who completed at least one posttreatment assessment. Motor disability based on modified H&Y scores, motor function and complications of therapy pre- and posttreatment were compared using Wilcoxon Signed Rank test. Chi-squared test was used to compare outcomes by age and sex. Frequencies of adverse reactions were recorded to evaluate the tolerability of the medication. RESULTS: Ten patients (mean age 63 ± 9.7 years), 3 male and 7 female, were enrolled in the study. Patients were given apomorphine for at most 16 days. The doses used were 2.5 mg/0.50 mL (n = 2), 3 mg/0.60 mL (n = 6), 4 mg/0.80 mL (n = 1) and 7 mg/1.40 mL (n = 1). After obtaining the threshold dose, two patients discontinued treatment. Eight of nine patients showed significant improvement in H&Y scores after treatment (p < 0.017). There was marked improvement after 10 days of treatment in at least five of 10 patients in terms of motor function using UPDRS, which included tremor (p < 0.034), rigidity (p < 0.002), facial expression (p < 0.014), finger taps (p < 0.008), foot taps (p < 0.014) and gait (p < 0.006). Significant changes from pre- to posttreatment scores in the frequency of dyskinesias (p < 0.010) and dystonia (p < 0.025) were observed. Nine focus areas of AIMS showed significant improvements in the muscles of facial expression (p < 0.020), upper (p < 0.016) and lower extremities (p < 0.010), incapacitation by abnormal movement (p < 0.010) and patients' awareness of abnormal movements (p < 0.039). Six patients experienced adverse events, none of which were related to the study drug. CONCLUSION: Apomorphine hydrochloride pump infusion therapy is potentially effective and safe in the treatment of motor fluctuations in Filipino patients with PD. This pilot study springboards safe engagements of Filipino PD patients in multicenter, large-scale trials.

17.
Public Health Nurs ; 39(3): 553-561, 2022 05.
Article in English | MEDLINE | ID: mdl-34902170

ABSTRACT

OBJECTIVES: This study examined Filipinos' health information-seeking behaviors, specifically their information engagement and apprehension of getting the COVID-19 vaccine, the reasons for vaccination, and how these factors influenced their decision to get vaccinated. DESIGN: Quantitative, cross-sectional, and predictive approaches. SAMPLE: This study conducted a national online survey using convenience sampling (n = 2709). MEASUREMENT: The Health Information Orientation Scale (HIOS) and Statista.com's "reasons for not getting a COVID-19 vaccination" were used to collect data. Demographic characteristics that predict information engagement and apprehension were identified using multivariate linear regression analysis. RESULTS: Responses to information engagement and apprehension revealed "often true" and "sometimes true," respectively. The majority of participants intended to receive the COVID-19 vaccine. "Concerned about the vaccine's safety" is the most common reason for not getting vaccinated. Female gender, college graduate, employed, and using social media to obtain COVID-19 vaccine information were all significant predictors of information engagement and apprehension. Information engagement and apprehension were predicted by age and religion, respectively. CONCLUSIONS: Policymakers should consider how people seek information regarding the COVID-19 vaccine and why some people refuse to get vaccinated. Additionally, public health nurses should educate the public about the safety of COVID-19 vaccines.


Subject(s)
COVID-19 Vaccines , COVID-19 , COVID-19/prevention & control , Cross-Sectional Studies , Female , Humans , Information Seeking Behavior , SARS-CoV-2 , Vaccination
18.
Palliat Support Care ; : 1-5, 2022 Sep 28.
Article in English | MEDLINE | ID: mdl-36168286

ABSTRACT

Providing end-of-life care within the cultural context of a Filipino patient in the United States is a complex process for clinicians, patients, and their families. An inclusive approach is crucial, especially because a significant proportion of patients belong to minority groups such as Filipinos, who represent the fourth largest group of immigrants in the United States as of data available in 2019. The case provided in this paper highlights the importance of family, religion, and finances in guiding the best possible way of providing end-of-life care for Filipino patients with cancer. At the end of this review, we discuss concrete action points that may give a non-Filipino physician a deeper understanding of end-of-life care for Filipinos.

19.
J Community Psychol ; 50(7): 3122-3140, 2022 09.
Article in English | MEDLINE | ID: mdl-35199333

ABSTRACT

This study identified resilience processes at the individual, family, and community levels among Filipino migrant domestic workers (MDWs). Resilience processes highlight strengths and resources that can enhance positive adaptation to problems that affect this vulnerable migrant group. Data came from focus groups and key informant interviews involving 27 MDWs and 7 key informants. Data was analyzed using thematic analysis and organized according to the socioecological model. Results revealed 7 resilience processes. Financial coping, health management, and spirituality were found across levels. Companionship and emotional support are transacted within family and community levels, whereas expanding knowledge and support occurs at individual and community levels. MDWs and their families prioritize each family member, whereas the community provides legal support. Resilience processes exist across ecological levels. However, individual resilience processes are insufficient, thus necessitating collective agency through familial and community resilience processes and building social structures that facilitate resilience.


Subject(s)
Transients and Migrants , Adaptation, Psychological , Family/psychology , Focus Groups , Humans , Spirituality
20.
J Ethn Subst Abuse ; : 1-15, 2022 Dec 29.
Article in English | MEDLINE | ID: mdl-36579697

ABSTRACT

Tobacco product use rates among Native Hawaiian/Pacific Islander (NHPI), Asian American, and Filipino American young adults in Hawai'i have risen rapidly in recent years following the introduction of electronic nicotine delivery systems. Though some research has examined tobacco use correlates for these demographics of young adults, research examining protective factors, such as cultural connectedness, is lacking. Additionally, research that disaggregates Asian Americans from Pacific Islanders is scarce, despite the differing risk and protective factors that have been determined for each group. This study separately examined cultural connectedness among NHPIs, Asian Americans, and Filipino Americans to help fill the gaps in the current tobacco product literature. The findings indicated that Asian Americans and Filipino Americans who identify more with their own cultures are less likely to use e-cigarettes; however, this relationship was not supported for NHPIs. No significant evidence was found to indicate a relationship between cultural connectedness and combustible cigarette use among any of the sampled groups. The lack of relationship between cultural connectedness and e-cigarette use among Native Hawaiians may be explained by measurement limitations in the study, and suggest the need for more culturally competent scales (e.g., an enculturation scale) that account for Indigenous status.

SELECTION OF CITATIONS
SEARCH DETAIL