ABSTRACT
Pemphigus disease and mucous membrane pemphigoid are autoimmune blistering diseases (AIBDs) which may involve both oral and extra-oral tissues. The Bristol Joint Oral Medicine and Dermatology Combined Clinic was set up in 2014, with the primary aim of improving the standard of care for patients with AIBDs. This interdisciplinary approach aimed to address the medical management challenges due to the multisite nature of these AIBDs.We present a narrative report of the clinical work undertaken within this clinic, focused on the management of this patient cohort within a five-year span (2017-2022). This report outlines the multisite nature of AIBDs and the range of topical and systemic treatments that were employed to achieve adequate disease control and optimise outcomes for patients. We reflect on the experiential benefits of this multidisciplinary clinic extended beyond immediate patient benefits to areas such as specialist training, both from a dermatologist's and oral physician's perspective.
Subject(s)
Dermatology , Oral Medicine , Pemphigoid, Benign Mucous Membrane , Pemphigoid, Bullous , Pemphigus , Humans , Mucous Membrane , Pemphigoid, Benign Mucous Membrane/diagnosis , Pemphigoid, Benign Mucous Membrane/therapy , Pemphigoid, Bullous/drug therapy , Pemphigus/therapyABSTRACT
Las enfermedades perianales del adulto, de carácter no infeccioso y no neoplásico, son un motivo de consulta poco frecuente. Se caracterizan por la variedad de su etiología y de su sintomatología clínica, y plantean dificultad en el diagnóstico y en la terapéutica. El objetivo del presente trabajo es abordar una patología que plantea la necesidad de una intervención interdisciplinaria. Se incluyen consideraciones anatomopatológicas, clínicas y terapéuticas. (AU)
Noninfectious, non- neoplasic perianal affections are uncommon diseases. They are characterized by the variety of the etiology and clinical symptomatology, posing difficulty in diagnosis and therapeutics. The objective of this paper is to address a pathology that raises the need for interdisciplinary intervention anatomopathological, clinical and therapeutic considerations are included. (AU)
Subject(s)
Humans , Adult , Anus Diseases/diagnosis , Anus Diseases/therapy , Patient Care Team , Skin Diseases, Vesiculobullous/diagnosis , Skin Diseases, Vesiculobullous/therapy , Dermatitis Herpetiformis/diagnosis , Dermatitis Herpetiformis/therapy , Pemphigoid, Benign Mucous Membrane/diagnosis , Pemphigoid, Benign Mucous Membrane/therapy , Pemphigus/diagnosis , Pemphigus/therapy , Stevens-Johnson Syndrome/diagnosis , Stevens-Johnson Syndrome/therapy , Pemphigus, Benign Familial/diagnosis , Pemphigus, Benign Familial/therapy , Dermatitis, Contact/diagnosis , Dermatitis, Contact/therapyABSTRACT
El penfigoide cicatricial o de mucosas es una patología que afecta principalmente a la mucosa oral y ocular. Sólo en 25% de los pacientes afecta también la piel y en alrededor de 10% de los pacientes compromete a la mucosa faringo-laríngea, produciendo en los casos severos disnea que incluso puede requerir traqueostomía. En el tratamiento del penfigoide cicatricial habitualmente se utilizan corticoides e inmunosupresores. En este artículo presentamos un caso de una mujer de 69 años con diagnóstico de penfigoide cicatricial que se manifiesta con disfagia y se comprueba con nasofibroscopía una estenosis supraglótica. Se discute el diagnóstico y manejo de esta patología poco habitual.
Cicatricial or mucous membranes pemphigoid is a rare pathology that affects mainly the ocular and oral mucosae. In only 25% of patients the skin is affected, and in 10%, the pharyngolaryngeal mucosa, resulting in serious cases in dyspnea that could even require a tracheostomy. Treatment is usually based on corticoids and immunosupressors. In this article we present the case of a 69 year old woman diagnosed with cicatricial pemphigoid, that presented dysphagia. A nasoendoscopy revealed supraglottic stenosis. Diagnosis and treatment of this uncommon disease are discussed.
Subject(s)
Humans , Female , Aged , Laryngostenosis/etiology , Pemphigoid, Benign Mucous Membrane/complications , Pemphigoid, Benign Mucous Membrane/diagnosis , Pemphigoid, Benign Mucous Membrane/therapy , Dyspnea/etiology , Deglutition Disorders/etiology , Oral Ulcer/etiologyABSTRACT
Os autores iniciam o desenvolvimento do tema alteraçoes de tecidos moles da boca, esclarecendo à classe médica sobre as principais doenças vesicobolhosas, condiçoes ulcerativas e lesoes verrucosas papilares.