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Org Biomol Chem
; 17(40): 8982-8986, 2019 10 28.
Artículo
en Inglés
| MEDLINE
| ID: mdl-31584061
RESUMEN
A facile microwave assisted three-component protocol allows the synthesis of chiral aryl-1,2-mercaptoamines in water in a few minutes with high yields, bypassing the use of toxic aziridine intermediates. The chiral 1,2-mercaptoamines were then deracemized through enzymatic resolution of the racemates using monoamine oxidase (MAO-N) biocatalysts.