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1.
Microsurgery ; 44(4): e31176, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38553855

RESUMEN

BACKGROUND: The use of scapular tip chimeric free flaps (STFFs) for reconstructing mandibular defects has recently become popular, but its utility relative to other bone-containing free flaps remains debatable. The aim of the report is to describe how technical modification of STFF impacted in its use for mandibular reconstruction also commenting results obtained in a unicentric series of patients. PATIENTS AND METHODS: Patients undergoing mandibular reconstruction using an STFF from January 1, 2014 to June 1, 2022 were retrospectively enrolled in this report. We collected data on chimeric flap type, bone management, vascular pedicles, and the final outcomes. In total, 31 patients (13 men and 18 women) with a mean age of 68 years were enrolled. According to the classification system of Urken, 15 patients had body defects, while 7 had ramus defects, another 7 had symphysis defects, and 2 had both ramus and bodily defects. STFF was always harvested working in two equips simultaneously, in supine position. Dissection included preparation of chimeric components of the flap as latissimus dorsi, serratus and scapular tip. After pedicle dissection scapular bone was cut basing on reconstructive needing with a rectangular (stick) shape including the border of the scapula. In cases of longer bone harvesting, circumflex pedicle was also included to perfuse the upper portion of the scapular border. In five cases, the STFF was harvested with only the scapular angle component, and was thus a composite osteomuscular flap; for the remaining 26 cases, a chimeric STFF was used. Circumflex pedicle was included for eight patients. Six of the seven patients with symphyseal defects underwent a single osteotomy. RESULTS: The average length of the harvested was 69.92 mm (maximum length = 104 mm). The average height of transplanted bone was 26.78 mm (maximum height = 44.2 mm). Mouth-opening was normal in 25 patients, limited in 6 patients, and severely impaired in no patients. The cosmetic results were rated as excellent by 20 patients, good by 8 patients, and poor by 3 patients. CONCLUSION: The STFF is an excellent option for mandibular reconstruction when other flaps are not available and for patients in poor general condition. Technical innovations here presented made possible to harvest long bone segments with accurate shape thanks to osteotomies if needed and with adequate soft tissues components of the chimeric flap, ensuring satisfactory functional and cosmetic results.


Asunto(s)
Colgajos Tisulares Libres , Reconstrucción Mandibular , Procedimientos de Cirugía Plástica , Masculino , Humanos , Femenino , Anciano , Colgajos Tisulares Libres/trasplante , Reconstrucción Mandibular/métodos , Estudios Retrospectivos , Escápula/trasplante
2.
J Craniofac Surg ; 2024 Feb 29.
Artículo en Inglés | MEDLINE | ID: mdl-38421169

RESUMEN

PURPOSE: Aplasia cutis congenita (ACC) is a heterogeneous group of congenital disorders characterized by the absence of epidermis, dermis, appendages, subcutaneous tissue, and bone. The aim of the study is to describe a clinical report of ACC of the scalp treated with skin expanders. CLINICAL REPORT: In October 2019, a 16-year-old female patient underwent scalp expansion with 2 rectangular devices (150 and 250 cm3; Radovan Mentor-Johnson&Johnson). The inflation started 30 days after surgery and continued once every 7 to 10 days to gain 10% of overexpansion. After 3 months, the patient underwent the second surgical step with the expanded scalp transposed to close the defect. Clinical examination 6 months after surgery revealed an acceptable cosmetic result with a hidden surgical scar and hair growth in the previous area of frontoparietal alopecia. CONCLUSION: Skin expander for the reconstruction of extensive ACC defects of the scalp is a valid procedure.

3.
Neurol Sci ; 44(9): 3107-3122, 2023 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-37087504

RESUMEN

BACKGROUND: The principal conditions differentiating disorders of consciousness (DOC) patients are the unresponsive wakefulness syndrome/vegetative state (UWS/VS) and the minimally conscious state (MCS). Many individuals who suffer from sudden-onset severe brain injury move through stages of UWS/VS and MCS before regaining full awareness. In some patients, the DOC condition is protracted for years (PDOC). In this study, we observed PDOC patients for 6 months to assess possible changes in their level of consciousness. METHODS: We enrolled 40 PDOC patients, 23 UWS/VS and 17 MCS hosted in a dedicated unit for long-term brain injury care. The time from injury was 472 ± 533 days for UWS/VS and 1090 ± 1079 days for MCS. The Wessex Head Injury Matrix (WHIM), Coma Recovery Scale-R (CRS-R), and Nociception Coma Scale were administered monthly for 6 months. RESULTS: During the period of assessment, the percentage of UWS/VS shifted from 58 to 45%, while for the MCS, from 42 to 55%. A positive correlation was found for the UWS/VS patients between the months of observation with the CRS-R total score and WHIM total numbers of behaviors (TNB). In the UWS/VS group, the CRS-R auditive and visual subscales correlated positively with the observation time. During the whole period of observation, 8 patients had constant CRS-R total scores while the WHIM TNB changed in 7 of them. CONCLUSION: Our findings demonstrated that the monthly assessment of PDOC by means of the CRS-R and WHIM was able to detect also subtle changes in consciousness level.


Asunto(s)
Lesiones Encefálicas , Traumatismos Craneocerebrales , Humanos , Estado de Conciencia/fisiología , Coma , Trastornos de la Conciencia/diagnóstico , Lesiones Encefálicas/diagnóstico , Vigilia , Estado Vegetativo Persistente/diagnóstico
4.
J Craniofac Surg ; 34(7): 2181-2184, 2023 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-37403219

RESUMEN

AIM OF THE STUDY: We introduce a technical variant of the standard preauricular approach to treat intracapsular and condylar neck fractures: the modified preauricular transparotid approach (MPTA). The main modification, when compared with the conventional submandibular approach, is that the incision of the superficial musculoaponeurotic system is performed directly above the parotid gland, and the buccal branch of the facial nerve is dissected in a retrograde way within the parotid gland. CASE SERIES: Between January 2019 and December 2020 at the Maxillofacial Departments of "Ospedale Maggiore" of Parma and "Policlinico San Martino" of Genoa 6 patients affected by intracapsular and condylar neck fractures underwent open reduction and internal with MPTA. Surgery was uneventful in all patients; no infections occurred in any of the cases; the mean procedure duration was 85 minutes, ranging from 75 to 115 minutes. At the 1-year follow-up, all patients had stable occlusion with a natural, well-balanced morphology of the face and adequate dynamic excursion of the mandible. CONCLUSION: MPTA is particularly suited for intracapsular and condylar neck fractures. Morbidity is negligible in terms of damage to the facial nerve, vascular injuries, and esthetic deformity.

5.
J Craniofac Surg ; 34(1): e15-e19, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-35984042

RESUMEN

AIM: In 2006 following the development of dedicated osteosynthesis plates, Meyer and colleagues reported a successful clinical study of condylar fractures treated by a modified submandibular approach; it was called high submandibular approach or "Strasbourg approach." The aim of this study is to describe the high submandibular approach step by step. CASE SERIES: Between January 2010 and December 2015 at the Maxillofacial Unit of the Hospital "Policlinico San Martino" 13 patients affected by subcondylar fracture underwent open reduction and internal with high submandibular approach. Surgery was uneventful in all patients; no infections occurred in any of the cases; the mean procedure duration was 89 minutes, ranging from 66 to 125 minutes. The mean hospital stay was 2.9 days, ranging from 2 to 6 days. At the 1-year follow-up, all patients had stable occlusion with a natural, well-balanced morphology of the face and adequate dynamic excursion of the mandible. CONCLUSIONS: The morbidity is negligible in terms of damage to the facial nerve, vascular injuries, and aesthetic deformity. The authors think that further prospective clinical trials are necessary to assess and eventually develop this approach.


Asunto(s)
Fracturas Mandibulares , Humanos , Fracturas Mandibulares/diagnóstico por imagen , Fracturas Mandibulares/cirugía , Cóndilo Mandibular/cirugía , Estética Dental , Mandíbula/cirugía , Nervio Facial , Fijación Interna de Fracturas/métodos , Placas Óseas
6.
J Craniofac Surg ; 34(6): 1760-1765, 2023 Sep 01.
Artículo en Inglés | MEDLINE | ID: mdl-37322594

RESUMEN

PURPOSE: Scientific literature considers maxillomandibular advancement (MMA) as the most effective surgical treatment for the management of adult obstructive sleep apnea syndrome (OSAS). Maxillomandibular advancement enlarges the pharyngeal space by expanding the skeletal framework. Moreover, it projects the soft tissue of the cheeks, the mouth, and the nose in the aging face, which is characterized by multiple signs affecting the middle third and the lower third. The potential of orthognathic surgery (double jaw surgical advancement) of expanding the skeletal foundation to increase the facial drape support and to rejuvenate the face by a "reverse face-lift" is now recognized. The aim of this study was to review the surgical outcomes after MMA in terms of respiratory function and assessment of facial esthetics. METHODS: We retrospectively reviewed the charts of all patients affected by OSAS who underwent maxillomandibular advancement between January 2010 and December 2015 in 2 tertiary hospitals (IRCCS Policlinico San Martino of Genoa and IRCCS Policlinico Ca' Granda of Milan). During the postoperative follow-up examination, all patients underwent polysomnographic examination and esthetic assessment to evaluate the respiratory function and facial rejuvenation after double jaw surgical advancement. RESULTS: The final study sample included 25 patients (5 females, 20 males). The overall success rate of the surgical treatment (apnea/hypopnea index, AHI <20) was 79%; the overall rate of surgical cure (AHI <5) was 47%. Twenty-three patients (92%) showed a degree of rejuvenation after MMA. CONCLUSIONS: Maxillomandibular advancement is currently the most effective surgical treatment for the management of OSAS in adult patients who are not responders to medical treatment. "Reverse face-lift" is the consequence of the double jaw surgical advancement.


Asunto(s)
Avance Mandibular , Síndromes de la Apnea del Sueño , Apnea Obstructiva del Sueño , Adulto , Masculino , Femenino , Humanos , Estudios Retrospectivos , Avance Mandibular/métodos , Maxilar/cirugía , Estética Dental , Apnea Obstructiva del Sueño/cirugía , Resultado del Tratamiento
7.
J Craniofac Surg ; 34(6): 1744-1747, 2023 Sep 01.
Artículo en Inglés | MEDLINE | ID: mdl-37433202

RESUMEN

INTRODUCTION: Scapular tip free flap (STFF) has become today one of the workhorse flaps for maxillary reconstruction; recently, the possibility of extending the vascular supply by adding to the angular branch of the circumflex pedicle up to its periosteal entrance in the lateral border of the scapula has been proposed as a reliable technique to improve the length of perfused bone when STFF is used for mandibular reconstruction. The purpose of this study was to evaluate the patients who had received microvascular reconstruction of the mandible with STFF vascularized by both the circumflex scapular artery via the periosteal branch and the thoracodorsal artery via the angular artery. METHODS: A retrospective chart review was conducted for all patients who underwent reconstruction with an STFF for mandibular defect between January 2016 and December 2020 at the University Hospital of Parma. The outcome was evaluated by assessing dietary intake (unrestricted, soft, liquid, and tube feed) and speech (normal, intelligible, partially intelligible, and unintelligible). RESULTS: The final study sample included 9 patients (5 men and 4 women). The average patient age was 68.9 years (range, 59.9-74.8 y) at the time of surgery. There was no flap loss. A 1-year postoperative computed tomography scan revealed full osteointegration of the flap. CONCLUSIONS: Our results show that the STFF is a valuable reconstructive option, especially in patients with complex head and neck defects requiring soft and hard tissues.


Asunto(s)
Colgajos Tisulares Libres , Reconstrucción Mandibular , Masculino , Humanos , Femenino , Persona de Mediana Edad , Anciano , Colgajos Tisulares Libres/irrigación sanguínea , Reconstrucción Mandibular/métodos , Estudios Retrospectivos , Mandíbula/cirugía , Escápula
8.
Aesthetic Plast Surg ; 46(6): 2905-2911, 2022 12.
Artículo en Inglés | MEDLINE | ID: mdl-35851809

RESUMEN

INTRODUCTION: Surgical correction of facial asymmetry is commonly performed in at least two stages. Recently, because of the long duration of a two-step procedure, the demand for a one-step procedure has increased. Our study aims to present a fully digitalized workflow for one-stage mandibular contouring (MC) and bimaxillary surgery to correct severe facial asymmetry using 3D technology. MATERIALS AND METHODS: A retrospective monocentric study was conducted for all patients affected by severe facial asymmetry who had undergone MC and orthognathic surgery between January 2018 and June 2020 at the Face Surgery Center, in Parma, Italy. RESULTS: The final study sample included 20 patients (12 women and 8 men). The mean age of the patients at the time of surgery was 20.8 years (range: 18-25 years). At the one-year follow-up, all patients had stable occlusion with a symmetric face. Mandibular angle degree (Ar-Go-Me) increased significantly from 113. 6° to 122.7° at the left side and from 113.3° to 122.7° at the right side (p < 0.05) (Table 1). The mandibular width (Go-Go) decreased from 116.5 to 106.4 mm (p < 0.05). CONCLUSION: A fully digitalized workflow for one-stage MC and bimaxillary surgery is a safe and valid option to correct facial asymmetry. CAD CAM technology is an indispensable tool to obtain predictable results. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .


Asunto(s)
Cirugía Ortognática , Humanos , Femenino , Adolescente , Adulto Joven , Adulto , Asimetría Facial/cirugía , Estudios Retrospectivos , Italia
9.
Aesthetic Plast Surg ; 46(1): 183-193, 2022 02.
Artículo en Inglés | MEDLINE | ID: mdl-34131790

RESUMEN

PURPOSE: Facial aging is the consequence of many mechanisms involving the bones and the "soft tissue" (skin, fat, ligaments, muscles, and periosteum) of the face such as downward migration of the soft tissue, adipose and muscular tissue atrophy, and skeletal resorption. The potential of orthognathic surgery (double jaw surgical advancement) of expanding the skeletal foundation to increase the facial drape support is now recognized and widely popularized by several authors. The aim of this study was to analyze the rejuvenation change of the face after bimaxillary advancement for orthognathic surgery, focusing on the previously mentioned stigmata of the middle and the lower third of the aging face. MATERIALS AND METHODS: A retrospective monocentric chart review was conducted for all patients affected by aging signs of the face who underwent orthognathic surgery between January 2015 and December 2019 at the Face Surgery Center (Parma, Italy). During the postoperative follow-up examination, all patients underwent anthropometric photographs and esthetic assessment to evaluate facial rejuvenation after double jaw surgical advancement. RESULTS: After application of the exclusion criteria, the final study sample included 85 patients (53 females, 32 males). Eighty-three patients (97%) showed a degree of rejuvenation after maxillo-mandibular advancement (MMA); the score of the postoperative face was less than the score of the preoperative face. Two patients reported no significant postoperative change; none reported a more aging face, with a successful "reverse face-lift" occurred in 97% of our cases. CONCLUSION: "Reverse face-lift" by bimaxillary advancement is a surgical procedure which is indicated for a selected group of middle-aged patients with a diagnosis of bimaxillary skeletal retrusion or posterior divergence very motivated to an extreme rejuvenation; this procedure provides support for the facial mask resulting in whole facial rejuvenation.


Asunto(s)
Procedimientos Quirúrgicos Ortognáticos , Ritidoplastia , Huesos Faciales , Femenino , Humanos , Masculino , Persona de Mediana Edad , Procedimientos Quirúrgicos Ortognáticos/métodos , Rejuvenecimiento , Estudios Retrospectivos , Ritidoplastia/métodos
10.
J Surg Oncol ; 120(4): 707-714, 2019 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-31364178

RESUMEN

BACKGROUND: The subclavicular pedicled flap is based on the thoracic branch of the supraclavicular artery, and it represents a versatile reconstructive option for low-middle third face defects. Since its use in head and neck surgical oncology has not been popularized yet, we propose its application for oral cavity reconstruction after cancer resection by showing favorable results. METHODS: Eighteen subclavicular pedicled flaps were used to treat intraoral defects after oral squamous-cell cancer resection between June 2015 and December 2018. Tumor dissection type, complications, donor and reconstructed area results, and functional and aesthetic outcomes were assessed. RESULTS: No major complications were observed and all of the flaps survived. Adjuvant therapy was administered without delay when needed, and all of the patients had normal functional outcomes and good aesthetic results. CONCLUSIONS: The subclavicular flap is an excellent choice for the reconstruction of oral cavity defects. Selection of patients should exclude positive lower-third neck node and include appropriate informed consent for women due to the possibility of deformity of the breast. In our opinion, this flap has the potential for common application given its consistent anatomy and donor site advantages, including long pedicle, high pivot point, and relatively unlimited flap width.


Asunto(s)
Carcinoma de Células Escamosas/cirugía , Neoplasias de la Boca/cirugía , Procedimientos de Cirugía Plástica/métodos , Colgajos Quirúrgicos , Pared Torácica/cirugía , Anciano , Anciano de 80 o más Años , Carcinoma de Células Escamosas/patología , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Neoplasias de la Boca/patología , Pronóstico , Tasa de Supervivencia , Pared Torácica/patología
11.
Artículo en Inglés | MEDLINE | ID: mdl-30537718

RESUMEN

OBJECTIVE: The buccal fat pad (BFP) has been progressively introduced into clinical practice for oral defect reconstruction. This study describes our experience with this technique and compares indications in the literature and outcomes. METHODS: We prospectively enrolled 24 patients presenting oral surgical defects and treated between January 2012 and January 2015 at our institution. They all were eligible for BFP defect reconstruction. A comprehensive literature review was performed from 1977 onwards and surgical indications and results were compared. RESULTS: All 24 BFP procedures showed excellent recovery and uneventful follow-up. Literature review confirmed a global success rate of 96.2% for a reported number of 1,635 patients with multiple surgical indications. BFP showed very low morbidity and failure rates in accordance with the outcomes reported in the literature, and the high patient compliance together with the easy harvesting of this surgical technique make it a good reconstructive option in cases of small-to-medium size oral defects in patients with a high rate of comorbidities or as salvage/second option. CONCLUSION: The BFP is worthy of consideration for the reconstruction of selected mouth defects, due to its easy mobilization, excellent blood supply, and minimal donor-site morbidity, where shape and size represent its main limitations, and a defect's location influences its pliability.


Asunto(s)
Tejido Adiposo , Mejilla , Procedimientos Quirúrgicos Orales , Procedimientos de Cirugía Plástica , Colgajos Quirúrgicos , Humanos
12.
J Surg Oncol ; 117(5): 1092-1099, 2018 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-29432642

RESUMEN

BACKGROUND AND OBJECTIVES: Reconstruction of tongue cancer defects is challenging due to the complex anatomy and physiology of the tongue. Here, we classify patterns of tongue tissue loss and describe a treatment algorithm for achieving good functional and oncologic outcomes. METHODS: We retrospectively reviewed 50 tongue squamous-cell carcinomas surgically treated between January 2010-June 2015. Cancer resection and tongue reconstruction were stratified according to the missing anatomical subunits. RESULTS: A type 1 defect is a unilateral and marginal defect, not crossing the midline, and not extending to the posterior-third of the tongue. Type 2 involves the two-anterior-thirds of the mobile body, not crossing the midline, without posterior-third evolvement. Type 3 involves the two-anterior-thirds of the mobile body of the tongue with contralateral extension. Type 4 extends to the tongue base. Type 5 defect comprises any of the previous defects along with involvement of the floor of the mouth. Type 2 and 3 defects were the most common. Microvascular reconstruction was performed in 23 out of 50 patients. Complications included infection, partial necrosis, dehiscence, and microvascular thrombosis. CONCLUSIONS: Our classification system and treatment algorithm represent a reliable method of addressing management of tongue defects.


Asunto(s)
Algoritmos , Carcinoma de Células Escamosas/cirugía , Glosectomía , Procedimientos de Cirugía Plástica , Neoplasias de la Lengua/cirugía , Carcinoma de Células Escamosas/patología , Estudios de Seguimiento , Humanos , Pronóstico , Estudios Retrospectivos , Colgajos Quirúrgicos , Neoplasias de la Lengua/patología
13.
ScientificWorldJournal ; 2015: 463829, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-25893211

RESUMEN

The operational model and strategies developed at the Institute S. Anna-RAN to be applied in the care and neurorehabilitation of subjects with disorders of consciousness (DOC) are described. The institute units are sequentially organized to guarantee appropriate care and provide rehabilitation programs adapted to the patients' clinical condition and individual's needs at each phase of evolution during treatment in a fast turnover rate. Patients eligible of home care are monitored remotely. Transferring advanced technology to a stage of regular operation is the main mission. Responsiveness and the time windows characterized by better residual responsiveness are identified and the spontaneous/induced changes in the autonomic system functional state and biological parameters are monitored both in dedicated sessions and by means of an ambient intelligence platform acquiring large databases from traditional and innovative sensors and interfaced with knowledge management and knowledge discovery systems. Diagnosis of vegetative state/unresponsive wakefulness syndrome or minimal conscious state and early prognosis are in accordance with the current criteria. Over one thousand patients with DOC have been admitted and treated in the years 1998-2013. The model application has progressively shortened the time of hospitalization and reduced costs at unchanged quality of services.


Asunto(s)
Trastornos de la Conciencia/rehabilitación , Modelos Neurológicos , Rehabilitación Neurológica , Atención al Paciente , Trastornos de la Conciencia/diagnóstico , Trastornos de la Conciencia/fisiopatología , Bases de Datos como Asunto , Frecuencia Cardíaca , Humanos , Monitoreo Fisiológico , Dolor/complicaciones , Dolor/fisiopatología , Resultado del Tratamiento
14.
J Craniofac Surg ; 26(3): 650-4, 2015 May.
Artículo en Inglés | MEDLINE | ID: mdl-25974767

RESUMEN

BACKGROUND: Airway obstruction, associated with mandibular hypoplasia, is a frequent complication in syndromic pediatric patients. The clinical signs of airway obstruction change from mild positional obstruction to severe respiratory distress with cyanosis. The young age of the patients makes medical management extremely complex. METHODS: The purpose was to evaluate the success of surgery, evaluating the expansion of the respiratory volumes measured by computer tomography analyzed through a software (SimPlant Pro 15). Twelve patients with mandibular hypoplasia and respiratory distress were treated between December 2010 and December 2013. Eleven of them had tracheostomy in the preoperative period. The goal of surgery was to prevent permanent tracheostomy or to remove it, if present. RESULTS: Volume and surface area increased by an average of 279.2% and 89.4%, respectively. Tracheostomy was avoided in 1 patient who underwent surgery precociously, and it was removed in 10 patients. Only 1 case failed in volume airway augmentation, and tracheostomy was not removed. CONCLUSIONS: Computer tomography can calculate the cross-sectional areas of the airway in 3 planes of space: coronal, sagittal, and axial. In most patients, changes in airways have been accompanied by improvements in sleep and breathing, allowing for the removal of tracheostomy with an improved quality of life. Three-dimensional reconstruction of airways revealed a useful tool to better understand the success of surgery. LEVEL OF EVIDENCE: IV.


Asunto(s)
Obstrucción de las Vías Aéreas/cirugía , Imagenología Tridimensional , Maloclusión/cirugía , Osteogénesis por Distracción/efectos adversos , Procedimientos de Cirugía Plástica/métodos , Tomografía Computarizada por Rayos X/métodos , Tráquea/cirugía , Obstrucción de las Vías Aéreas/diagnóstico por imagen , Obstrucción de las Vías Aéreas/etiología , Preescolar , Femenino , Humanos , Lactante , Masculino , Reoperación , Síndrome
15.
J Craniofac Surg ; 25(3): 788-92, 2014 May.
Artículo en Inglés | MEDLINE | ID: mdl-24820708

RESUMEN

BACKGROUND: Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is the most serious complication of bisphosphonates therapy. Despite that several treatment modalities have been described, aggressive surgical treatment approach with wide bone resection and vascularized microsurgical reconstruction are controversial. The aim of this study was to evaluate the clinical outcome of 8 new cases of BRONJ treated with radical resection and mandibular reconstruction with fibula free flap, to enforce the evidence about the reliability of this treatment option. METHODS: Retrospective data of 8 patients with BRONJ who underwent segmental mandibulectomy and reconstruction with osteocutaneous fibula free flap from January 2004 to January 2008 were collected, including 6 patients with stage 3 BRONJ and 2 patients with recalcitrant stage 2 BRONJ. RESULTS: All patients were white, with a mean age of 64.7 years (range, 53-77 y), and 62.5% were women. All bisphosphonates were administered intravenously, and all patients had mandibular localization. The mean period of follow-up was 28.9 months. No flap loss or minor complications and no BRONJ recurrence were observed. All patients were able to ambulate pain-free. CONCLUSIONS: Despite initial concerns regarding reliability of the mandibular free-flap reconstruction after BRONJ, this method seems to be a safe and feasible option in cancer patients with reasonable life expectancy, with complete BRONJ resolution and life quality improvement. Our findings confirm data previously published by other authors, without complication and with a much longer median follow-up time.


Asunto(s)
Osteonecrosis de los Maxilares Asociada a Difosfonatos/cirugía , Trasplante Óseo/métodos , Colgajos Tisulares Libres/trasplante , Osteotomía Mandibular/métodos , Reconstrucción Mandibular/métodos , Microcirugia/métodos , Anciano , Estudios de Factibilidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos
16.
Front Neurol ; 15: 1338873, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38426164

RESUMEN

The progressive improvement of the living conditions and medical care of the population in industrialized countries has led to improvement in healthcare interventions, including rehabilitation. From this perspective, Telerehabilitation (TR) plays an important role. TR consists of the application of telemedicine to rehabilitation to offer remote rehabilitation services to the population unable to reach healthcare. TR integrates therapy-recovery-assistance, with continuity of treatments, aimed at neurological and psychological recovery, involving the patient in a family environment, with an active role also of the caregivers. This leads to reduced healthcare costs and improves the continuity of specialist care, as well as showing efficacy for the treatment of cognitive disorders, and leading to advantages for patients and their families, such as avoiding travel, reducing associated costs, improving the frequency, continuity, and comfort of performing the rehabilitation in its own spaces, times and arrangements. The aim of this consensus paper is to investigate the current evidence on the use and effectiveness of TR in the cognitive field, trying to also suggest some recommendations and future perspectives. To the best of our knowledge, this is the first consensus paper among multiple expert researchers that comprehensively examines TR in different neurological diseases. Our results supported the efficacy and feasibility of TR with good adherence and no adverse events among patients. Our consensus summarizes the current evidence for the application of cognitive TR in neurological populations, highlighting the potential of this tool, but also the limitations that need to be explored further.

17.
J Craniofac Surg ; 24(3): e258-60, 2013 May.
Artículo en Inglés | MEDLINE | ID: mdl-23714984

RESUMEN

Oral lichen planus is a chronic autoinflammatory mucositis. Oral lesions are predominantly white; they tend to be bilateral while involving the buccal mucosa especially cheek, tongue, gums, lips, and palate. Many topical and systemic agents are currently used with unpredictable results. Fat grafting is characterized by the placement of multiple parcels of purified fat with blunt cannulas; at the beginning, it was introduced to improve facial aesthetics. Recently, it has been translated to other surgical cases such as posttraumatic deformities and craniofacial anomalies and as ancillary reconstructive procedure after tumor resections. The successful results of this procedure encouraged us to use this approach to a clinical case of oral lichen planus refractory to conventional therapy.


Asunto(s)
Grasa Abdominal/trasplante , Autoinjertos/trasplante , Liquen Plano Oral/cirugía , Grasa Abdominal/cirugía , Anciano , Femenino , Estudios de Seguimiento , Enfermedades de las Encías/cirugía , Humanos , Enfermedades de los Labios/cirugía , Masticación/fisiología , Mucosa Bucal/cirugía , Dimensión del Dolor , Recolección de Tejidos y Órganos/métodos , Enfermedades de la Lengua/cirugía , Resultado del Tratamiento
18.
Funct Neurol ; 28(1): 29-38, 2013.
Artículo en Inglés | MEDLINE | ID: mdl-23731913

RESUMEN

The aim of this study was to validate the Progression of Autonomies Scale (PAS) for the evaluation of autonomies in severe acquired brain injury patients. The PAS design is based on a model of progressive recovery of autonomies and is organized in three domains (Personal, Domestic and Extra-domestic). Scores assigned range from zero to three. The PAS items gather information about the patient's perception and awareness of his/her disability(ies) on admission and perception of his/her improvement at the end of a rehabilitation process. The PAS was administered to 127 inpatients on admission to and at discharge from a rehabilitation program. All 127 inpatients, recruited in a prospective multicenter study, completed the rehabilitation program. The statistical analysis identified a total of 38 items to be retained in the PAS, out of an initial 82 items. The results provide evidence of the validity and reliability of the PAS in its final version.


Asunto(s)
Lesiones Encefálicas/psicología , Lesiones Encefálicas/rehabilitación , Evaluación de la Discapacidad , Autonomía Personal , Actividades Cotidianas , Adolescente , Adulto , Anciano , Análisis por Conglomerados , Terapia Cognitivo-Conductual , Interpretación Estadística de Datos , Femenino , Escala de Coma de Glasgow , Humanos , Masculino , Persona de Mediana Edad , Terapia Ocupacional , Estudios Prospectivos , Psicometría , Recuperación de la Función , Reproducibilidad de los Resultados , Resultado del Tratamiento , Trabajo , Adulto Joven
19.
Biomedicines ; 12(1)2023 Dec 28.
Artículo en Inglés | MEDLINE | ID: mdl-38255189

RESUMEN

Introduction: The Wessex Head Injury Matrix (WHIM) was developed to assess patients with disorders of consciousness (DOC) and was tested in terms of inter-rater reliability (IRR) and test-retest reliability (TRR) in the year 2000. The American Congress of Rehabilitation and Medicine reported that IRR and TRR were unproven. We aim to assess the reliability of the WHIM in prolonged DOC patients (PDOC). Methods: A total of 51 PDOC patients (32 unresponsive wakefulness syndrome (UWS/VS) and 19 minimally conscious state (MCS)) who were hosted in a dedicated unit for long-term brain injury care were enrolled. The time from injury ranged from 182 to 3325 days. Two raters administered the Coma Recovery Scale-Revised (CRS-R) and the WHIM to test the IRR and TRR. The TRR was administered two weeks after the first assessment. Results: For the CRS-R, the agreement in IRR and TRR was perfect between the two raters. The agreement for the WHIM ranged from substantial to almost perfect for IRR and from fair to substantial for the TRR. Conclusions: The WHIM showed a strong IRR when administered by expert raters and strongly correlated with the CRS-R. This study provides further evidence of the psychometric qualities of the WHIM and the importance of its use in PDOC patients.

20.
J Oral Maxillofac Surg ; 70(10): 2433-9, 2012 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-22285336

RESUMEN

PURPOSE: To propose an algorithm for the preoperative management of patients with obstructive sleep apnea syndrome (OSAS) and review the surgical outcomes in such patients. MATERIALS AND METHODS: This prospective cohort study involved 71 patients with OSAS who underwent presurgical upper airway endoscopy and cephalometry before being assigned to treatment categories based on the site(s) of obstruction, the pattern of collapse, the characteristics of the soft tissue, the air space between the base of the tongue and the posterior wall of the pharynx, and the severity of OSAS. Six months after surgery, they were followed up using polysomnography and the Epworth Sleepiness Scale. The pre- and postsurgical data were compared using a paired Student t test. RESULTS: The mean preoperative apnea/hypopnea index of the 71 patients (61 male and 10 female) was 40.98 events/hour (range, 14.7 to 87.6 events/hr), and the mean postoperative apnea/hypopnea index was 13.96 events/hour (range, 0 to 20 events/hr). The difference was statistically significant (P < .001). CONCLUSIONS: This algorithm was developed on the principle that every patient with OSAS should be considered individually. In the authors' opinion, taking into account the number, site(s), pattern, and degree of the collapse/obstruction is a reasonable means of ensuring the correct diagnosis and treatment.


Asunto(s)
Algoritmos , Planificación de Atención al Paciente , Apnea Obstructiva del Sueño/clasificación , Adulto , Anciano , Obstrucción de las Vías Aéreas/clasificación , Obstrucción de las Vías Aéreas/cirugía , Cefalometría , Estudios de Cohortes , Endoscopía , Femenino , Estudios de Seguimiento , Humanos , Hipofaringe/patología , Masculino , Persona de Mediana Edad , Obstrucción Nasal/clasificación , Obstrucción Nasal/cirugía , Nariz/patología , Nariz/cirugía , Orofaringe/patología , Procedimientos Quirúrgicos Ortognáticos , Enfermedades Faríngeas/clasificación , Enfermedades Faríngeas/cirugía , Polisomnografía , Cuidados Preoperatorios , Estudios Prospectivos , Apnea Obstructiva del Sueño/cirugía , Fases del Sueño/fisiología , Lengua/patología , Resultado del Tratamiento
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