RESUMEN
AgBase (http://www.agbase.msstate.edu/) provides resources to facilitate modeling of functional genomics data and structural and functional annotation of agriculturally important animal, plant, microbe and parasite genomes. The website is redesigned to improve accessibility and ease of use, including improved search capabilities. Expanded capabilities include new dedicated pages for horse, cat, dog, cotton, rice and soybean. We currently provide 590 240 Gene Ontology (GO) annotations to 105 454 gene products in 64 different species, including GO annotations linked to transcripts represented on agricultural microarrays. For many of these arrays, this provides the only functional annotation available. GO annotations are available for download and we provide comprehensive, species-specific GO annotation files for 18 different organisms. The tools available at AgBase have been expanded and several existing tools improved based upon user feedback. One of seven new tools available at AgBase, GOModeler, supports hypothesis testing from functional genomics data. We host several associated databases and provide genome browsers for three agricultural pathogens. Moreover, we provide comprehensive training resources (including worked examples and tutorials) via links to Educational Resources at the AgBase website.
Asunto(s)
Agricultura , Bases de Datos Genéticas , Genómica , Modelos Genéticos , Animales , Animales Domésticos/genética , Gatos , Productos Agrícolas/genética , Perros , Perfilación de la Expresión Génica , Análisis de Secuencia por Matrices de Oligonucleótidos , Programas Informáticos , Interfaz Usuario-ComputadorRESUMEN
More than 98% of reported human listeriosis cases are caused by Listeria monocytogenes serotypes within lineages I and II. Serotypes within lineage III (4a and 4c) are commonly isolated from environmental and food specimens. We report the first complete genome sequence of a lineage III isolate, HCC23, which will be used for comparative analysis.
Asunto(s)
Bagres/microbiología , Genoma Bacteriano , Listeria monocytogenes/genética , Animales , ADN Bacteriano/genética , Listeria monocytogenes/clasificación , Listeria monocytogenes/aislamiento & purificación , Datos de Secuencia Molecular , Análisis de Secuencia de ADNRESUMEN
Clostridium carboxidivorans strain P7(T) is a strictly anaerobic acetogenic bacterium that produces acetate, ethanol, butanol, and butyrate. The C. carboxidivorans genome contains all the genes for the carbonyl branch of the Wood-Ljungdahl pathway for CO(2) fixation, and it encodes enzymes for conversion of acetyl coenzyme A into butanol and butyrate.