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Eur J Appl Physiol ; 110(1): 215-8, 2010 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-20414670

RESUMEN

A model that describes the blood lactate concentration (BLC) dynamics [BLC(t)] of a Wingate Anaerobic Test (WAnT) as a function of (a) BLC at the start of exercise (BLC(0)), (b) extra-vascular increase in lactate (A), (c) two corresponding velocity constants of appearance (k (1)) and disappearance (k (2)) of lactate into and out of the blood requires that BLC(0) is equal to resting BLC (BLC(rest)). We developed a model that considers an elevated BLC(0). 19 males performed WAnTs with warm-ups increasing (p < 0.001) BLC(0). The goodness of each individual fit improved (p < 0.05) if the difference between BLC(rest) and BLC(0) (DeltaBLC) was higher than 1.0 mmol l(-1). All differences between old and new model (p < 0.05) in A, k (1) and k (2) were interrelated with and increased with DeltaBLC (p < 0.05). The new model well describes BLC(t) and prevents substantial errors concerning lactate generation and dynamics if BLC(0) is elevated by more than 1.0 mmol l(-1).


Asunto(s)
Ejercicio Físico , Ácido Láctico/sangre , Modelos Biológicos , Contracción Muscular , Músculo Esquelético/metabolismo , Adulto , Biomarcadores/sangre , Prueba de Esfuerzo , Humanos , Cinética , Masculino , Recuperación de la Función , Regulación hacia Arriba , Adulto Joven
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