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1.
The integrated stress response-related expression of CHOP due to mitochondrial toxicity is a warning sign for DILI liability.
Liver Int
; 44(3): 760-775, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38217387
2.
Mapping the cellular response to electron transport chain inhibitors reveals selective signaling networks triggered by mitochondrial perturbation.
Arch Toxicol
; 96(1): 259-285, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34642769
3.
The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment.
Arch Toxicol
; 95(12): 3745-3775, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34626214
4.
High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability.
Arch Toxicol
; 93(10): 2895-2911, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31552476
5.
Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury.
Arch Toxicol
; 93(2): 385-399, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30426165
6.
Relationship between increasing concentrations of two carcinogens and statistical image descriptors of foci morphology in the cell transformation assay.
J Appl Toxicol
; 37(6): 709-720, 2017 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27917502
7.
A network-based transcriptomic landscape of HepG2 cells uncovering causal gene-cytotoxicity interactions underlying drug-induced liver injury.
Toxicol Sci
; 198(1): 14-30, 2024 Feb 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38015832
8.
Identifying multiscale translational safety biomarkers using a network-based systems approach.
iScience
; 26(3): 106094, 2023 Mar 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-36895646
9.
Application of high-throughput transcriptomics for mechanism-based biological read-across of short-chain carboxylic acid analogues of valproic acid.
ALTEX
; 39(2): 207220, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35040482
10.
An ensemble learning approach for modeling the systems biology of drug-induced injury.
Biol Direct
; 16(1): 5, 2021 01 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33435983
11.
The eTRANSAFE Project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and Perspectives.
Pharmaceuticals (Basel)
; 14(3)2021 Mar 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33800393
12.
In vitro and bioinformatics mechanistic-based approach for cadmium carcinogenicity understanding.
Toxicol In Vitro
; 65: 104757, 2020 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-31904401
13.
Toxicogenomics applied to in vitro Cell Transformation Assay reveals mechanisms of early response to cadmium.
Toxicol In Vitro
; 48: 232-243, 2018 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-29408670
14.
eTRANSAFE: data science to empower translational safety assessment.
Nat Rev Drug Discov
; 22(8): 605-606, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37316648
15.
A comprehensive statistical classifier of foci in the cell transformation assay for carcinogenicity testing.
Toxicol In Vitro
; 45(Pt 3): 351-358, 2017 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-28461232
16.
An improved classification of foci for carcinogenicity testing by statistical descriptors.
Toxicol In Vitro
; 29(7): 1839-50, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26183914
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