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1.

Phosphatases maintain low catalytic activity of SGK1: DNA damage resets the balance in favor of phosphorylation.

Gu, Wenxue; Zheng, Hongyan; Canessa, Cecilia M.

J Biol Chem ; 299(8): 104941, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-37343701

2.

Lipid droplets and autophagosomes together with chaperones fine-tune expression of SGK1.

Ghani, Madiha J; Gu, Wenxue; Chen, Zhuyuan; Canessa, Cecilia M.

J Cell Mol Med ; 26(10): 2852-2865, 2022 05.

Artículo en Inglés | MEDLINE | ID: mdl-35393773

3.

A method for activation of endogenous acid-sensing ion channel 1a (ASIC1a) in the nervous system with high spatial and temporal precision.

Li, Tianbo; Yang, Youshan; Canessa, Cecilia M.

J Biol Chem ; 289(22): 15441-8, 2014 May 30.

Artículo en Inglés | MEDLINE | ID: mdl-24727474

4.

The neuronal-specific SGK1.1 (SGK1_v2) kinase as a transcriptional modulator of BAG4, Brox, and PPP1CB genes expression.

González-Fernández, Rebeca; Ávila, Julio; Arteaga, María F; Canessa, Cecilia M; Martín-Vasallo, Pablo.

Int J Mol Sci ; 16(4): 7462-77, 2015 Apr 02.

Artículo en Inglés | MEDLINE | ID: mdl-25849655

5.

Impact of recovery from desensitization on acid-sensing ion channel-1a (ASIC1a) current and response to high frequency stimulation.

Li, Tianbo; Yang, Youshan; Canessa, Cecilia M.

J Biol Chem ; 287(48): 40680-9, 2012 Nov 23.

Artículo en Inglés | MEDLINE | ID: mdl-23048040

6.

Heterogeneous nuclear ribonucleoprotein A2/B1 is a tissue-specific aldosterone target gene with prominent induction in the rat distal colon.

Hernández-Díaz, Iván; Giraldez, Teresa; Morales, Silvia; Hernandez, Guadalberto; Salido, Eduardo; Canessa, Cecilia M; Alvarez de la Rosa, Diego.

Am J Physiol Gastrointest Liver Physiol ; 304(2): G122-31, 2013 Jan 15.

Artículo en Inglés | MEDLINE | ID: mdl-23139218

7.

A flexible GAS belt responds to pore mutations changing the ion selectivity of proton-gated channels.

Chen, Zhuyuan; Lin, Sheng; Xie, Tianze; Lin, Jin-Ming; Canessa, Cecilia M.

J Gen Physiol ; 154(1)2022 01 03.

Artículo en Inglés | MEDLINE | ID: mdl-34766968

8.

Asn415 in the beta11-beta12 linker decreases proton-dependent desensitization of ASIC1.

Li, Tianbo; Yang, Youshan; Canessa, Cecilia M.

J Biol Chem ; 285(41): 31285-91, 2010 Oct 08.

Artículo en Inglés | MEDLINE | ID: mdl-20675379

9.

Leu85 in the beta1-beta2 linker of ASIC1 slows activation and decreases the apparent proton affinity by stabilizing a closed conformation.

Li, Tianbo; Yang, Youshan; Canessa, Cecilia M.

J Biol Chem ; 285(29): 22706-12, 2010 Jul 16.

Artículo en Inglés | MEDLINE | ID: mdl-20479002

10.

A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons.

Arteaga, Maria F; Coric, Tatjana; Straub, Christoph; Canessa, Cecilia M.

Proc Natl Acad Sci U S A ; 105(11): 4459-64, 2008 Mar 18.

Artículo en Inglés | MEDLINE | ID: mdl-18334630

11.

An arginine residue in the outer segment of hASIC1a TM1 affects both proton affinity and channel desensitization.

Chen, Zhuyuan; Kuenze, Georg; Meiler, Jens; Canessa, Cecilia M.

J Gen Physiol ; 153(5)2021 05 03.

Artículo en Inglés | MEDLINE | ID: mdl-33851970

12.

Structure and analysis of nanobody binding to the human ASIC1a ion channel.

Wu, Yangyu; Chen, Zhuyuan; Sigworth, Fred J; Canessa, Cecilia M.

Elife ; 102021 07 28.

Artículo en Inglés | MEDLINE | ID: mdl-34319232

13.

Two residues in the extracellular domain convert a nonfunctional ASIC1 into a proton-activated channel.

Li, Tianbo; Yang, Youshan; Canessa, Cecilia M.

Am J Physiol Cell Physiol ; 299(1): C66-73, 2010 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-20427715

14.

Multiple translational isoforms give functional specificity to serum- and glucocorticoid-induced kinase 1.

Arteaga, Maria Francisca; Alvarez de la Rosa, Diego; Alvarez, Jose A; Canessa, Cecilia M.

Mol Biol Cell ; 18(6): 2072-80, 2007 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-17377066

15.

Simple chordates exhibit a proton-independent function of acid-sensing ion channels.

Coric, Tatjana; Passamaneck, Yale J; Zhang, Ping; Di Gregorio, Anna; Canessa, Cecilia M.

FASEB J ; 22(6): 1914-23, 2008 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-18211956

16.

A valve-like mechanism controls desensitization of functional mammalian isoforms of acid-sensing ion channels.

Wu, Yangyu; Chen, Zhuyuan; Canessa, Cecilia M.

Elife ; 82019 05 02.

Artículo en Inglés | MEDLINE | ID: mdl-31045491

17.

Structural biology: unexpected opening.

Canessa, Cecilia M.

Nature ; 449(7160): 293-4, 2007 Sep 20.

Artículo en Inglés | MEDLINE | ID: mdl-17882209

18.

Gating of acid-sensitive ion channel-1: release of Ca2+ block vs. allosteric mechanism.

Zhang, Ping; Sigworth, Fred J; Canessa, Cecilia M.

J Gen Physiol ; 127(2): 109-17, 2006 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-16418400

19.

Single channel properties of rat acid-sensitive ion channel-1alpha, -2a, and -3 expressed in Xenopus oocytes.

Zhang, Ping; Canessa, Cecilia M.

J Gen Physiol ; 120(4): 553-66, 2002 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-12356856

20.

Effects of aldosterone on biosynthesis, traffic, and functional expression of epithelial sodium channels in A6 cells.

Alvarez de la Rosa, Diego; Li, Hui; Canessa, Cecilia M.

J Gen Physiol ; 119(5): 427-42, 2002 May.

Artículo en Inglés | MEDLINE | ID: mdl-11981022

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Phosphatases maintain low catalytic activity of SGK1: DNA damage resets the balance in favor of phosphorylation.

Lipid droplets and autophagosomes together with chaperones fine-tune expression of SGK1.

A method for activation of endogenous acid-sensing ion channel 1a (ASIC1a) in the nervous system with high spatial and temporal precision.

The neuronal-specific SGK1.1 (SGK1_v2) kinase as a transcriptional modulator of BAG4, Brox, and PPP1CB genes expression.

Impact of recovery from desensitization on acid-sensing ion channel-1a (ASIC1a) current and response to high frequency stimulation.

Heterogeneous nuclear ribonucleoprotein A2/B1 is a tissue-specific aldosterone target gene with prominent induction in the rat distal colon.

A flexible GAS belt responds to pore mutations changing the ion selectivity of proton-gated channels.

Asn415 in the beta11-beta12 linker decreases proton-dependent desensitization of ASIC1.

Leu85 in the beta1-beta2 linker of ASIC1 slows activation and decreases the apparent proton affinity by stabilizing a closed conformation.

A brain-specific SGK1 splice isoform regulates expression of ASIC1 in neurons.

An arginine residue in the outer segment of hASIC1a TM1 affects both proton affinity and channel desensitization.

Structure and analysis of nanobody binding to the human ASIC1a ion channel.

Two residues in the extracellular domain convert a nonfunctional ASIC1 into a proton-activated channel.

Multiple translational isoforms give functional specificity to serum- and glucocorticoid-induced kinase 1.

Simple chordates exhibit a proton-independent function of acid-sensing ion channels.

A valve-like mechanism controls desensitization of functional mammalian isoforms of acid-sensing ion channels.

Structural biology: unexpected opening.

Gating of acid-sensitive ion channel-1: release of Ca2+ block vs. allosteric mechanism.

Single channel properties of rat acid-sensitive ion channel-1alpha, -2a, and -3 expressed in Xenopus oocytes.

Effects of aldosterone on biosynthesis, traffic, and functional expression of epithelial sodium channels in A6 cells.