1.
Chembiochem
; 14(12): 1419-22, 2013 Aug 19.
Artículo
en Inglés
| MEDLINE
| ID: mdl-23836614
RESUMEN
Wake up, protein! Small molecules that directly activate proteins are rare and their discovery opens new avenues for the development of drugs and chemical tools to probe the functions and mechanisms of protein targets. To address the one-sided dichotomy between enzyme inhibition and activation, we describe a series of procaspase activators as chemical tools in the study of caspase biology.