Detalles de la búsqueda
1.
A Genetic Map of the Response to DNA Damage in Human Cells.
Cell
; 182(2): 481-496.e21, 2020 07 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-32649862
2.
NFATC2IP is a mediator of SUMO-dependent genome integrity.
Genes Dev
; 38(5-6): 233-252, 2024 Apr 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38503515
3.
Endogenous DNA 3' Blocks Are Vulnerabilities for BRCA1 and BRCA2 Deficiency and Are Reversed by the APE2 Nuclease.
Mol Cell
; 78(6): 1152-1165.e8, 2020 06 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-32516598
4.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.
Mol Syst Biol
; 2024 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38580884
5.
Liver Injury Caused by Green Tea Extract in PD-1-/- Mice: An Impaired Immune Tolerance Model for Idiosyncratic Drug-Induced Liver Injury.
Chem Res Toxicol
; 34(3): 849-856, 2021 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33617238
6.
Rotenone Increases Isoniazid Toxicity but Does Not Cause Significant Liver Injury: Implications for the Hypothesis that Inhibition of the Mitochondrial Electron Transport Chain Is a Common Mechanism of Idiosyncratic Drug-Induced Liver Injury.
Chem Res Toxicol
; 32(7): 1423-1431, 2019 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31251588
7.
Characterization of TCDD-inducible poly-ADP-ribose polymerase (TIPARP/ARTD14) catalytic activity.
Biochem J
; 475(23): 3827-3846, 2018 12 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30373764
8.
3-Methylcholanthrene Induces Chylous Ascites in TCDD-Inducible Poly-ADP-Ribose Polymerase (Tiparp) Knockout Mice.
Int J Mol Sci
; 20(9)2019 May 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31083300
9.
The Effects of Immune Modulators on Amodiaquine-Induced Liver Injury.
Chem Res Toxicol
; 31(8): 739-744, 2018 08 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-29938495
10.
How Reactive Metabolites Induce an Immune Response That Sometimes Leads to an Idiosyncratic Drug Reaction.
Chem Res Toxicol
; 30(1): 295-314, 2017 01 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-27775332
11.
TCDD-inducible poly-ADP-ribose polymerase (TIPARP/PARP7) mono-ADP-ribosylates and co-activates liver X receptors.
Biochem J
; 473(7): 899-910, 2016 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26814197
12.
Loss of the Mono-ADP-ribosyltransferase, Tiparp, Increases Sensitivity to Dioxin-induced Steatohepatitis and Lethality.
J Biol Chem
; 290(27): 16824-40, 2015 Jul 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-25975270
13.
Response to the Letter to the Editor Concerning the Article "Rotenone Increases Isoniazid Toxicity but Does Not Cause Liver Injury: Implications for the Hypothesis That Inhibition of the Mitochondrial Electron Transport Chain Is a Common Mechanism of Idiosyncratic Drug-Induced Liver Injury" by Bernard Fromenty.
Chem Res Toxicol
; 33(1): 5-6, 2020 01 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-31820941
14.
The use of PD-1 functional knockout rats to study idiosyncratic adverse reactions to nevirapine.
Toxicol Sci
; 2024 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38767978
15.
The development and characterization of a CRISPR/Cas9-mediated PD-1 functional knockout rat as a tool to study idiosyncratic drug reactions.
Toxicol Sci
; 198(2): 233-245, 2024 Mar 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-38230816
16.
The Putative Drosophila TMEM184B Ortholog Tmep Ensures Proper Locomotion by Restraining Ectopic Firing at the Neuromuscular Junction.
Mol Neurobiol
; 59(4): 2605-2619, 2022 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-35107803
17.
Artificial intelligence for the discovery of novel antimicrobial agents for emerging infectious diseases.
Drug Discov Today
; 27(4): 1099-1107, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-34748992
18.
Dissecting a disynaptic central amygdala-parasubthalamic nucleus neural circuit that mediates cholecystokinin-induced eating suppression.
Mol Metab
; 58: 101443, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35066159
19.
Transmembrane protein TMEM184B is necessary for interleukin-31-induced itch.
Pain
; 163(5): e642-e653, 2022 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34629389
20.
Testing Possible Risk Factors for Idiosyncratic Drug-Induced Liver Injury Using an Amodiaquine Mouse Model and Co-treatment with 1-Methyl-d-Tryptophan or Acetaminophen.
ACS Omega
; 6(7): 4656-4662, 2021 Feb 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-33644572