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1.

Nelonemdaz for Patients With Acute Ischemic Stroke Undergoing Endovascular Reperfusion Therapy: A Randomized Phase II Trial.

Hong, Ji Man; Lee, Jin Soo; Lee, Yeong-Bae; Shin, Dong Hoon; Shin, Dong-Ick; Hwang, Yang-Ha; Ahn, Seong Hwan; Kim, Jae Guk; Sohn, Sung-Il; Kwon, Sun U; Lee, Ji Sung; Gwag, Byoung Joo; Chamorro, Ángel; Choi, Dennis W.

Stroke ; 53(11): 3250-3259, 2022 11.

Artículo en Inglés | MEDLINE | ID: mdl-36065810

2.

Elevated plasma biomarkers of inflammation in acute ischemic stroke patients with underlying dementia.

Choi, Dennis W; Kim, Tae Song; Kim, Young Soo; Kim, Dong Jin.

BMC Neurol ; 20(1): 293, 2020 Aug 05.

Artículo en Inglés | MEDLINE | ID: mdl-32758167

3.

The Rescue on Reperfusion Damage in Cerebral Infarction by Nelonemdaz (RODIN) Trial: Protocol for a Double-Blinded Clinical Trial of Nelonemdaz in Patients with Hyperacute Ischemic Stroke and Endovascular Thrombectomy.

Lee, Jin Soo; Lee, Ji Sung; Gwag, Byoung Joo; Choi, Dennis W; An, Chun San; Kang, Hyun Goo; Song, Tae-Jin; Ahn, Seong Hwan; Kim, Chang Hun; Shin, Dong-Ick; Kwon, Sun U.

J Stroke ; 25(1): 160-168, 2023 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-36746385

4.

Excitotoxicity: Still Hammering the Ischemic Brain in 2020.

Choi, Dennis W.

Front Neurosci ; 14: 579953, 2020.

Artículo en Inglés | MEDLINE | ID: mdl-33192266

5.

Longitudinal multiparametric MRI study of hydrogen-enriched water with minocycline combination therapy in experimental ischemic stroke in rats.

Jiang, Zhao; Alamuri, Tharun T; Muir, Eric R; Choi, Dennis W; Duong, Tim Q.

Brain Res ; 1748: 147122, 2020 12 01.

Artículo en Inglés | MEDLINE | ID: mdl-32919984

6.

Safety and Optimal Neuroprotection of neu2000 in acute Ischemic stroke with reCanalization: study protocol for a randomized, double-blinded, placebo-controlled, phase-II trial.

Hong, Ji Man; Choi, Mun Hee; Sohn, Sung-Il; Hwang, Yang-Ha; Ahn, Seong Hwan; Lee, Yeong-Bae; Shin, Dong-Ick; Chamorro, Ángel; Choi, Dennis W.

Trials ; 19(1): 375, 2018 Jul 13.

Artículo en Inglés | MEDLINE | ID: mdl-30005644

7.

Neurodegeneration: cellular defences destroyed.

Choi, Dennis W.

Nature ; 433(7027): 696-8, 2005 Feb 17.

Artículo en Inglés | MEDLINE | ID: mdl-15716937

8.

Metabotropic glutamate receptor 1-induced upregulation of NMDA receptor current: mediation through the Pyk2/Src-family kinase pathway in cortical neurons.

Heidinger, Valerie; Manzerra, Pat; Wang, Xue Qing; Strasser, Uta; Yu, Shan-Ping; Choi, Dennis W; Behrens, M Margarita.

J Neurosci ; 22(13): 5452-61, 2002 Jul 01.

Artículo en Inglés | MEDLINE | ID: mdl-12097497

9.

Potassium channel blockers attenuate hypoxia- and ischemia-induced neuronal death in vitro and in vivo.

Wei, Ling; Yu, Shan Ping; Gottron, Frank; Snider, B Joy; Zipfel, Gregory J; Choi, Dennis W.

Stroke ; 34(5): 1281-6, 2003 May.

Artículo en Inglés | MEDLINE | ID: mdl-12677023

10.

Membrane-permeant chelators can attenuate Zn2+-induced cortical neuronal death.

Canzoniero, Lorella M T; Manzerra, Pat; Sheline, Christian T; Choi, Dennis W.

Neuropharmacology ; 45(3): 420-8, 2003 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-12871659

11.

Medicines for the mind: policy-based "pull" incentives for creating breakthrough CNS drugs.

Choi, Dennis W; Armitage, Robert; Brady, Linda S; Coetzee, Timothy; Fisher, William; Hyman, Steven; Pande, Atul; Paul, Steven; Potter, William; Roin, Benjamin; Sherer, Todd.

Neuron ; 84(3): 554-63, 2014 Nov 05.

Artículo en Inglés | MEDLINE | ID: mdl-25442934

12.

Exploratory clinical testing of neuroscience drugs.

Choi, Dennis W.

Nat Neurosci ; 5 Suppl: 1023-5, 2002 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-12403975

13.

nNOS(+) striatal neurons, a subpopulation spared in Huntington's Disease, possess functional NMDA receptors but fail to generate mitochondrial ROS in response to an excitotoxic challenge.

Canzoniero, Lorella M T; Granzotto, Alberto; Turetsky, Dorothy M; Choi, Dennis W; Dugan, Laura L; Sensi, Stefano L.

Front Physiol ; 4: 112, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-23720635

14.

Transient decrease in F-actin may be necessary for translocation of proteins into dendritic spines.

Ouyang, Yannan; Wong, Michael; Capani, Francisco; Rensing, Nick; Lee, Chul-Sang; Liu, Qun; Neusch, Clemens; Martone, Maryann E; Wu, Jane Y; Yamada, Kelvin; Ellisman, Mark H; Choi, Dennis W.

Eur J Neurosci ; 22(12): 2995-3005, 2005 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-16367766

15.

Neurotrophin and GDNF family ligands promote survival and alter excitotoxic vulnerability of neurons derived from murine embryonic stem cells.

Lee, Chul-Sang; Tee, Lee Y; Dusenbery, Susan; Takata, Toshihiro; Golden, Judith P; Pierchala, Brian A; Gottlieb, David I; Johnson, Eugene M; Choi, Dennis W; Snider, B Joy.

Exp Neurol ; 191(1): 65-76, 2005 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-15589513

16.

Transplantation of embryonic stem cells overexpressing Bcl-2 promotes functional recovery after transient cerebral ischemia.

Wei, Ling; Cui, Lin; Snider, B Joy; Rivkin, Mark; Yu, Steven S; Lee, Chul-Sang; Adams, Larry D; Gottlieb, David I; Johnson, Eugene M; Yu, Shan Ping; Choi, Dennis W.

Neurobiol Dis ; 19(1-2): 183-93, 2005.

Artículo en Inglés | MEDLINE | ID: mdl-15837573

17.

Cu2+ toxicity inhibition of mitochondrial dehydrogenases in vitro and in vivo.

Sheline, Christian T; Choi, Dennis W.

Ann Neurol ; 55(5): 645-53, 2004 May.

Artículo en Inglés | MEDLINE | ID: mdl-15122704

18.

Involvement of poly ADP ribosyl polymerase-1 in acute but not chronic zinc toxicity.

Sheline, Christian T; Wang, Hongmin; Cai, Ai-Li; Dawson, Valina L; Choi, Dennis W.

Eur J Neurosci ; 18(6): 1402-9, 2003 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-14511320

19.

NMDA antagonists exacerbate neuronal death caused by proteasome inhibition in cultured cortical and striatal neurons.

Snider, B Joy; Tee, Lee Y; Canzoniero, Lorella M T; Babcock, Debra J; Choi, Dennis W.

Eur J Neurosci ; 15(3): 419-28, 2002 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-11876769

20.

TrkB mediates BDNF-induced potentiation of neuronal necrosis in cortical culture.

Kim, Hyun-Jung; Hwang, Jung Jin; Behrens, M Margarita; Snider, B Joy; Choi, Dennis W; Koh, Jae-Young.

Neurobiol Dis ; 14(1): 110-9, 2003 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-13678672

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Nelonemdaz for Patients With Acute Ischemic Stroke Undergoing Endovascular Reperfusion Therapy: A Randomized Phase II Trial.

Elevated plasma biomarkers of inflammation in acute ischemic stroke patients with underlying dementia.

The Rescue on Reperfusion Damage in Cerebral Infarction by Nelonemdaz (RODIN) Trial: Protocol for a Double-Blinded Clinical Trial of Nelonemdaz in Patients with Hyperacute Ischemic Stroke and Endovascular Thrombectomy.

Excitotoxicity: Still Hammering the Ischemic Brain in 2020.

Longitudinal multiparametric MRI study of hydrogen-enriched water with minocycline combination therapy in experimental ischemic stroke in rats.

Safety and Optimal Neuroprotection of neu2000 in acute Ischemic stroke with reCanalization: study protocol for a randomized, double-blinded, placebo-controlled, phase-II trial.

Neurodegeneration: cellular defences destroyed.

Metabotropic glutamate receptor 1-induced upregulation of NMDA receptor current: mediation through the Pyk2/Src-family kinase pathway in cortical neurons.

Potassium channel blockers attenuate hypoxia- and ischemia-induced neuronal death in vitro and in vivo.

Membrane-permeant chelators can attenuate Zn2+-induced cortical neuronal death.

Medicines for the mind: policy-based "pull" incentives for creating breakthrough CNS drugs.

Exploratory clinical testing of neuroscience drugs.

nNOS(+) striatal neurons, a subpopulation spared in Huntington's Disease, possess functional NMDA receptors but fail to generate mitochondrial ROS in response to an excitotoxic challenge.

Transient decrease in F-actin may be necessary for translocation of proteins into dendritic spines.

Neurotrophin and GDNF family ligands promote survival and alter excitotoxic vulnerability of neurons derived from murine embryonic stem cells.

Transplantation of embryonic stem cells overexpressing Bcl-2 promotes functional recovery after transient cerebral ischemia.

Cu2+ toxicity inhibition of mitochondrial dehydrogenases in vitro and in vivo.

Involvement of poly ADP ribosyl polymerase-1 in acute but not chronic zinc toxicity.

NMDA antagonists exacerbate neuronal death caused by proteasome inhibition in cultured cortical and striatal neurons.

TrkB mediates BDNF-induced potentiation of neuronal necrosis in cortical culture.