1.
J Org Chem
; 74(15): 5614-7, 2009 Aug 07.
Artículo
en Inglés
| MEDLINE
| ID: mdl-19514745
RESUMEN
The gold-catalyzed cyclization of various alpha-amino-ynone derivatives gave the corresponding pyrrolin-4-ones in high yields. Moreover, the use of gold(III) oxide as catalyst allows a moderate to total stereocontrol during the cyclization. These pyrrolin-4-ones are highly useful intermediates for the synthesis of functionalized pyrrolidines and other natural products.