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1.
Grid-Type Quaternary Metallosupramolecular Compounds Inhibit Human Cholinesterases through Dynamic Multivalent Interactions.
Chembiochem
; 23(23): e202200456, 2022 12 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36193860
2.
Genes coding for transcription factors involved in stem cell maintenance are repressed by TGF-ß and downstream of Slug/Snail2 in COPD bronchial epithelial progenitors.
Mol Biol Rep
; 48(10): 6729-6738, 2021 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-34436724
3.
Development of versatile and potent monoquaternary reactivators of acetylcholinesterase.
Arch Toxicol
; 95(3): 985-1001, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33517499
4.
Chemoselective Hydrogenation of 6-Alkynyl-3-fluoro-2-pyridinaldoximes: Access to First-in-Class 6-Alkyl-3-Fluoro-2-pyridinaldoxime Scaffolds as New Reactivators of Sarin-Inhibited Human Acetylcholinesterase with Increased Blood-Brain Barrier Permeability.
Chemistry
; 26(65): 15035-15044, 2020 Nov 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32633095
5.
Rapid discovery of a selective butyrylcholinesterase inhibitor using structure-based virtual screening.
Bioorg Med Chem Lett
; 30(24): 127609, 2020 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33039562
6.
A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning.
J Med Chem
; 65(6): 4649-4666, 2022 03 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35255209
7.
Proliferation Genes Repressed by TGF-ß Are Downstream of Slug/Snail2 in Normal Bronchial Epithelial Progenitors and Are Deregulated in COPD.
Stem Cell Rev Rep
; 17(3): 703-718, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33495975
8.
Discovery of drug-like acetylcholinesterase inhibitors by rapid virtual screening of a 6.9 million compound database.
Chem Biol Drug Des
; 97(5): 1048-1058, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33455074
9.
Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime.
Biomolecules
; 10(6)2020 06 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32512884
10.
X-ray structures of human bile-salt activated lipase conjugated to nerve agents surrogates.
Toxicology
; 411: 15-23, 2019 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30359675
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