The adaptability and irrigation constraints analysis of the WOFOST model for grain production in the Songhua River Basin.

BACKGROUND: The Songhua River Basin, a vital grain-producing area in China, faces challenges due to the uneven distribution of water resources and the intensive water demands of agriculture. To enhance agricultural development and effectively manage water scarcity, it is essential to identify the water-saving potential of major staple crops - corn, wheat, and rice. This study enhances the World Food Studies (WOFOST) model by refining the day of year for the developmental vegetative stage (DVS), thereby improving the representation of phenological stages for spring maize, spring wheat, and rice within the model. This refinement offers a detailed analysis of the potential and rainfed yields. RESULTS: The results from the modified WOFOST model show promising simulation outcomes for the biomass and yield of maize, wheat, and rice, with Nash-Sutcliffe efficiency (NS) and index of agreement (IoA) values all exceeding 0.7. An analysis of photothermal potential yields (Yp) and rainfed yields (Yr) revealed minimal differences in yields for spring maize and rice across various rainfall frequencies. Specifically, the average photothermal utilization rates (LTs) are 93.57% for maize and 85.25% for rice. In contrast, the rainfed yield for wheat is lower than its photothermal yield, with an LT of 43.66%. CONCLUSIONS: These findings suggest that in the Songhua River Basin, maize and rice offer greater potential for water conservation compared to wheat. It is recommended to judiciously reduce irrigation during the growing seasons of spring maize and rice to help alleviate agricultural water use pressures. © 2024 Society of Chemical Industry.

Podocan affects C2C12 myogenic differentiation by enhancing Wnt/ß-catenin signaling.

Podocan, a small leucine-rich repeat protein, is a negative regulator of cell proliferation. In this study, we demonstrated that podocan is involved in the differentiation of C2C12 murine myoblasts. Podocan expression increased with the progression of C2C12 differentiation. As expect, siRNA-mediated podocan knockdown inhibited C2C12 differentiation, as indicated by inhibition of MYOG, MYH2, and desmin expression, as well as reductions in the differentiation and fusion indices. Overexpression of podocan using dCas9 technology promoted C2C12 cell differentiation. In addition, supplementation of culture medium with podocan influenced C2C12 differentiation. Podocan knockdown reduced Wnt/ß-catenin signaling, characterized by a reduction in the nuclear translocation of ß-catenin, whereas podocan overexpression had the opposite effect. Furthermore, treatment with XAV939, an inhibitor of Wnt/ß-catenin, reduced the podocan-mediated promotion of C2C12 differentiation. Induction of muscle injury in mice by bupivacaine administration suggested that podocan may play a role in muscle regeneration. In summary, our results suggest that podocan is required for normal C2C12 differentiation and that its role in myogenesis is mediated by the Wnt/ß-catenin pathway.

Illness perception characteristics and influencing factors in adult patients with myasthenia gravis in China.

OBJECTIVE: We aimed to examine the illness perception characteristics of patients with myasthenia gravis and analyze the associated factors. METHODS: A general information questionnaire, Illness Perception Questionnaire, and Simplified Coping Style Questionnaire were used to survey 90 patients with myasthenia gravis. One-way analysis of variance and multivariate linear regression were used for statistical analysis. RESULTS: The timeline (acute/chronic), consequence, and emotional representation scores of patients with myasthenia gravis were 18.31 ± 4.47, 18.58 ± 3.57, and 20.80 ± 4.56, respectively. Multivariate stepwise linear regression analysis showed that marital status, disease duration, educational level, disease type, and coping style are factors associated with illness perception in patients with myasthenia gravis. CONCLUSION: Patients who have myasthenia gravis have a negative illness perception. Medical professionals should provide targeted intervention measures based on the factors associated with illness perception.

[Comparison and Analysis of the Quantitative Methods for Pollutant Sources Load in Groundwater Contamination Risk Assessment].

Groundwater contamination risk assessment is an important basis for the protection of groundwater resources and the prevention and control of groundwater pollution. Its evaluation system is usually composed of three elements, which is vulnerability, pollutant source load and groundwater value. The pollutant source load plays an important role in risk assessment. Because of the difference among methods for pollutant sources load quantification, there will inevitably be different demand for the basic information survey on pollutant sources, as well as unknown impact on the final assessment results. In order to explore the impact of quantitative methods for pollutant sources load on groundwater contamination risk assessment, a case study was conducted in the mesoscale region of alluvial fan in Hutuo River, China. The two representative methods of grading index and quantitative index assessment systems were applied to quantify the pollutant sources load, in combination with the same vulnerability and groundwater value. The results constructed from different risk assessment systems were compared. The results showed that there were great differences between the two methods of quantification for pollutant sources load, and the result of contamination risk assessment also revealed significant differences in the feature of risk valve and the spatial distribution of the risk levels. The results of contamination risk assessment were strongly influenced by the choice of quantification for pollutant sources load methods. The grading index method was suitable for large scale region with lower precision of basic information and was simple, and the results of assessment had relatively lower reliability. The quantitative index method was suitable for the mesoscale and micro-scale region with higher precision of basic information and was relatively complicated, and the results of assessment had relatively higher reliability. It was shown that the scale effect of evaluation region had an important influence on the choice of methods.

Occurrence, distribution, and attenuation of pharmaceuticals and personal care products in the riverside groundwater of the Beiyun River of Beijing, China.

This study investigated the occurrence, seasonal-spatial distribution characteristics, and attenuation process of 15 pharmaceuticals and personal care products (PPCPs) in riverside sections of Beiyun River of Beijing. The overall PPCP levels both in surface water and riverside groundwater were moderate on the global scale, and showed higher concentrations in the dry season mainly caused by water temperature variation. Caffeine (CF), carbamazepine (CBZ), metoprolol (MTP), N,N-diethyl-meta-toluamide (DEET), diclofenac (DF), bezafibrate (BF), and gemfibrozil (GF) were seven representative PPCPs, because the rest eight studied compounds occurred in low concentrations and less than 15% of the total concentration of PPCPs. Caffeine and bezafibrate, respectively, was the most abundant compound in surface water and riverside groundwater, with median concentrations of 3020.0 and 125.0 ng L-1. Total concentrations of PPCPs in surface water were much higher than those in the riverside groundwater spatially. Attenuation of PPCPs during riverbank filtration was largely depending on the sources, site hydrogeological conditions, and physical-chemical properties of PPCPs, also was influenced by dissolved organic matter and environmental physicochemical parameters. CF, MTP, DEET, and CBZ were potential groundwater attenuation contaminants; DF, BF, and GF were groundwater-enriched contaminants based on their removal rates. Predominant removal mechanism of PPCPs like CF was biodegradation. Attenuation simulation showed that the one-way supply between Beiyun River and riverside groundwater, and further confirmed Beiyun River, was the main source of pharmaceutical compounds in the riverside groundwater.

[Distribution Characteristics of Fluoroquinolones Antibiotics in Surface Water and Groundwater from Typical Areas in A City].

In order to investigate the characteristics of 5 typical kinds of fluoroquinolones (FQs) pollution in waters from a city, surface water and groundwater samples from main drainage rivers and typical areas were collected, respectively. The conventional test and FQs concentrations analysis of the water samples were conducted. The results showed the concentration and composition of FQs in groundwater differed substantially from those in surface water. The average concentration of FQs in surface water was 789.1 ng x L(-1) with the main components of ofloxacin (OFL) and lomefloxacin (LOM). This value was higher than the average concentration of FQs in groundwater: 342.7 ng x L(-1) with the main components of norfloxacin (NOR) and lomefloxacin (LOM). The enrofloxacin (ENR) exhibited relatively lower levels in both surface water and groundwater as compared to others. The highest FQs concentrations in surface water were found in trenches, followed by tributaries and the main stream. For groundwater, FQs concentrations were relatively higher in the sewage riverside. A decreasing trend of FQs concentration was monitored with the increasing distance of sampling points to the drainage rivers and all components mentioned above showed similar changing trends. The results of this study preliminarily indicated that FQs in groundwater along the riverside probably came from the surface water.

[Contamination characteristics of fluoroquinolones in different kinds of soil profiles in Southeast suburb of Beijing].

Eighty-six soil samples were collected using Geoprobe soil sampler from 11 borehole profiles of Beijing Southeast suburb. The sampling sites could be divided into 8 kinds of landuse. Physical and chemical properties of samples were analyzed. The concentrations of 5 fluoroquinolones (FQs) were analyzed by the high-performance liquid chromatography. Results show that the average value of total concentrations of 5 FQs is 46.1 µg x kg(-1). Ofloxacin (OFL) is the predominant among them, and then is norfloxacin (NOR). Last comes to enrofloxacin (ENR), ciprofloxacin (CIP) and lomefloxacin (LOM). There are significant differences in FQs concentrations and kinds among the 8 land use types of soil profiles. The average value of total concentrations of 5 FQs decrease with an increasing of soil depth. The average concentration of OFL, NOR, LOM and ENR decrease with an increasing of soil depth. But CIP has the opposite result. Based on FQs concentrations from 42 soil samples with a depth among 0 to 3 meters, contamination characteristics of FQs were analyzed by fuzzy hierarchial clustering. Sampling sites of vegetable greenhouse, woods, sewage irrigation zone, groundwater irrigation zone, livestock and poultry farm, sediments from sewage river have similar components and contents of FQs, with less kinds and low concentration. In contrast, sampling sites of pharmaceutical enterprises and refuse landfill have more kinds and medium concentration of FQs.