Do all short stem types restore biomechanical parameters of the hip? Comparison according to femoral neck osteotomy levels.

PURPOSE: There is no consensus on ideal short femoral stem design. A classification system proposed by Feyen and Shimmin divides short stems in two types according to femoral neck osteotomy levels: subcapital (IIIA) and standard (IIIB). The study aims to determine which design type is more successful in restoring native biomechanical parameters and whether stem type has an impact on clinical results. METHODS: In this retrospective comparative study, patients that have undergone short stem hip arthroplasty were evaluated according to stem types: type IIIA (n = 52, 66.7%) (Mathys Optimys) and IIIB (n = 26, 33.3%) (Implantcast Aida and Smith & Nephew SMF). Pelvis X-rays were assessed in terms of femoral neck length, horizontal and vertical hip centres of rotation, horizontal and vertical femoral offsets, abductor lever arm lengths, leg lengths, and stem-shaft angles. Improvement in Harris hip scores, differences between post-operative and pre-operative measurements, and stem-shaft angles were evaluated and compared between two groups. RESULTS: Mean femoral neck resection (8.27 ± 6.68 mm in IIIA and 15 ± 6.33 mm in IIIB) was significantly different between both groups (p < 0.001). Harris hip scores were increased at post-operative six months in both groups with no difference (84.4 ± 6.4 and 84.6 ± 5.5, p = 0.4). The absolute values of differences between pre-operative and post-operative horizontal centres of rotation (p = 0.63), vertical centers of rotation (p = 0.75), horizontal femoral offsets (p = 0.78), vertical femoral offsets (p = 0.83), abductor lever arm distances (p = 0.63), and leg length (p = 0.21) measurements were not different between both groups. Stem positions were both varus with no statistically significant difference between groups (p = 0.14). CONCLUSION: We found no difference regarding restoration of biomechanical parameters between short stem designs with different levels of neck osteotomy. Additionally, short stem can mostly result in varus component positioning regardless of the level of neck osteotomy.

Risk factors associated with breakage of tibio-fibular syndesmotic screws.

PURPOSE: This retrospective study aimed to investigate the factors associated with the breakage of tibio-fibular syndesmotic screws (SS). METHODS: 69 patients with unstable AO-Weber Type 44-B ankle fractures who underwent three cortex SS (3.5 mm ø) fixation were included. Patients were followed for at least one year (mean, 18.3 ± 7.6 months). At the final follow-up, patients with broken (Group I) and intact (Group II) SS were compared regarding age, gender, height, weight, body mass index, fracture type, SS length, location, and orientation. Multivariate logistic regression was used to identify the independent risk factors associated with SS breakage. The sensitivity, specificity, cut-off value, and area under the ROC curve were analyzed. RESULTS: A stepwise backward logistic regression analysis revealed that age was the only independent predictor for SS breakage (OR = 0.938, 95% CI = 0.904-0.973, R2 = 0.270). ROC curve analysis demonstrated that patients younger than 36 years were associated with seven times increased risk of SS breakage [Odds ratio (95% CI), 7.042 (2.251-22.031)]. CONCLUSION: Age under 36 years was the only significant risk factor for SS breakage. The higher incidence of breakage of the syndesmotic screw can be informed to patients younger than 36.

Akkermansia muciniphila improves chronic colitis-induced enteric neuroinflammation in mice.

BACKGROUND: Inflammatory bowel diseases (IBD) are chronic diseases that are not fully understood. Drugs in use can only be applied for a short time due to their side effects. Therefore, research is needed to develop new treatment approaches. In addition, it has been proven that IBD causes degeneration in the enteric nervous system (ENS). In recent years, it has been discussed that probiotics may have positive effects in the prevention and treatment of inflammatory enteric degeneration. Akkermansia muciniphila (A. muciniphila) is an anaerobic bacterium found in the mucin layer of the intestinal microbiota. It has been found that the population of A. muciniphila decreases in the case of different diseases. In light of this information, the curative effect of A. muciniphila application on colitis-induced inflammation and enteric degeneration was investigated. METHODS: In this study, 5 weeks of A. muciniphila treatment in Trinitro-benzene-sulfonic acid (TNBS)-induced chronic colitis model was investigated. Colon samples were examined at microscopic, biochemical, and molecular levels. Fecal samples were collected before, during, and after treatment to evaluate the population changes in the microbiota. Specific proteins secreted from the ENS were evaluated, and enteric degeneration was examined. RESULTS: As a result of the research, the ameliorative effects of A. muciniphila were shown in the TNBS colitis model-induced inflammation and ENS damage. DISCUSSION: In light of these results, A. muciniphila can potentially be evaluated as a microbiome-based treatment for IBD with further clinical and experimental studies.

Comparison of single and double incision leg fasciotomy in disaster settings-Experience from 2023 Türkiye earthquakes.

INTRODUCTION: Although there are studies comparing methods for leg fasciotomy in compartment syndrome after fractures, choice of single or double fasciotomies in disasters was not investigated. The aim of this study was to compare the efficacy of single and double incision leg fasciotomy in the setting of disaster. METHODS: Patients that have undergone fasciotomy after 2023 Kahramanmaras earthquakes were retrospectively analyzed. The cases were separated into two groups as single incision and double incision according to the method of the first fasciotomy. The number of debridements after each fasciotomy, muscle group excisions, completion time of treatment, presence of amputation, the method of closure (primary closure or graft/flap) and positive results of wound cultures were analyzed and compared between two groups. RESULTS: 62 legs of 52 patients (22 females, 30 males, age 36.9 ± 11.2 years) with compartment syndrome that have undergone fasciotomy after 2023 Kahramanmaras earthquakes were included in the study. Single-incision group included 27 legs and double incision group included 35 legs. Amputation was needed in 15 patients (%24.2), six in single incision group and nine in double incision group. (p = 0.75). Compartment excision (eight patients in single incision, nine patients in double incision groups, p = 0.81), number of debridements (median 4 in both groups, p = 0.55), wound closure time (median 17 days in single incision, 22 days in double incision groups, p = 0.52), graft or flap requirement (11 patients in single incision, 16 patients in double incision groups, p = 0.53), positive culture results (15 patients in single incision, 16 patients in double incision groups, p = 0.44) were not different statistically between two groups. CONCLUSION: Single and double incision fasciotomy methods are equally effective and safe in treatment of compartment syndrome of the leg in disaster situations. To our knowledge, this is the first study comparing outcomes of single and double incision fasciotomy in disaster settings.