1.
Chem Commun (Camb)
; 59(5): 607-610, 2023 Jan 12.
Artículo
en Inglés
| MEDLINE
| ID: mdl-36533578
RESUMEN
The stereocontrolled synthesis of complex spirotricyclic systems containing an embedded syn-1,2-diaminocyclohexane unit is reported, based upon a dearomatising oxidation of phenols bearing pendant ureas capable of acting as double nucleophiles. This complexity-generating transformation yields products with rich functionality suitable for application in the synthesis of potentially bioactive compounds.