RESUMEN
BACKGROUND: Transcranial direct current stimulation (tDCS) is an effective neuromodulation adjunct to repetitive motor training in promoting motor recovery post-stroke. Finger tracking training is motor training whereby people with stroke use the impaired index finger to trace waveform-shaped lines on a monitor. Our aims were to assess the feasibility and safety of a telerehabilitation program consisting of tDCS and finger tracking training through questionnaires on ease of use, adverse symptoms, and quantitative assessments of motor function and cognition. We believe this telerehabilitation program will be safe and feasible, and may reduce patient and clinic costs. METHODS: Six participants with hemiplegia post-stroke [mean (SD) age was 61 (10) years; 3 women; mean (SD) time post-stroke was 5.5 (6.5) years] received five 20-min tDCS sessions and finger tracking training provided through telecommunication. Safety measurements included the Digit Span Forward Test for memory, a survey of symptoms, and the Box and Block test for motor function. We assessed feasibility by adherence to treatment and by a questionnaire on ease of equipment use. We reported descriptive statistics on all outcome measures. RESULTS: Participants completed all treatment sessions with no adverse events. Also, 83.33% of participants found the set-up easy, and all were comfortable with the devices. There was 100% adherence to the sessions and all recommended telerehabilitation. CONCLUSIONS: tDCS with finger tracking training delivered through telerehabilitation was safe, feasible, and has the potential to be a cost-effective home-based therapy for post-stroke motor rehabilitation. TRIAL REGISTRATION: NCT02460809 (ClinicalTrials.gov).
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Rehabilitación de Accidente Cerebrovascular/métodos , Telerrehabilitación/métodos , Estimulación Transcraneal de Corriente Directa/métodos , Adulto , Estudios de Factibilidad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Rehabilitación de Accidente Cerebrovascular/instrumentación , Telerrehabilitación/instrumentación , Estimulación Transcraneal de Corriente Directa/instrumentaciónRESUMEN
INTRODUCTION: In myopathy patients, it is useful to measure skeletal muscle forces. Conventional methods require voluntary muscle activation, which can be unreliable. We evaluated a device for nonvoluntary force assessment. METHODS: We tested 8 patients (unknown myopathy n = 2, inflammatory myopathy, facioscapulohumeral muscular dystrophy, mitochondrial myopathy, dysferlinopathy, multi-minicore disease, Becker-Kiener muscular dystrophy, n = 1 each). Isometric twitch torques of ankle dorsiflexors were measured after fibular nerve stimulation. RESULTS: Six patients had decreased torques vs. 8 controls (men: median Newton-meter 1.6 vs. 5.7, women: 0.2 vs. 3.9, both P < 0.0001). Values correlated with Manual Muscle Test results (r = 0.73; r(2) = 0.53; P < 0.0001). In weak dorsiflexors, torque could be measured despite lower signal-to-noise ratios. In 2 patients with hypertrophy, we measured increased torques. CONCLUSIONS: Nonvoluntary muscle force assessment can be used in patients with myopathies, and values correlate with voluntary forces determined by traditional methods. Muscle Nerve 53: 913-917, 2016.
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Contracción Isométrica/fisiología , Músculo Esquelético/fisiopatología , Enfermedades Musculares/patología , Enfermedades Musculares/fisiopatología , Adulto , Articulación del Tobillo/inervación , Estimulación Eléctrica , Electromiografía , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estadística como Asunto , Estadísticas no Paramétricas , Suiza , TorqueRESUMEN
OBJECTIVE: Ensuring proper respirator fit for individuals remains a persistent challenge in occupational environments, yet there is limited knowledge about how respirators interact with the face to "'fit." Previous studies have attempted to understand the association between face dimensions and respirator fit using traditional head/face anthropometry not specifically tailored for respirators. The purpose of this study was to assess and compare the ability of filtering facepiece respirator (FFR)-specific face anthropometry with traditional head/face anthropometry in exploring the relationship between facial dimensions and the fit of FFR. METHODS: The study utilized 3D face scans and quantitative fit factor scores from 56 participants to investigate the relationship between face anthropometry and FFR fit. Both FFR-specific and traditional anthropometric measurements were obtained through 3D anthropometric software. Intra-correlation of anthropometry was analyzed to evaluate the efficiency and effectiveness of FFR-specific and traditional anthropometry respectively. Principal component analysis (PCA) was conducted to test the usefulness of the PCA method for investigating various facial features. Logistic regression was used to develop fit association models by estimating the relationship between each face measurement set and the binary outcome of the fit test result. The prediction accuracy of the developed regression models was tested. RESULTS: FFR-specific face anthropometry consists of a set of measurements that can inform the detailed facial shape associated with the FFRs more effectively than traditional head/face anthropometry. While PCA may have been effective in reducing the variable dimensions for the relatively large parts of the human body such as upper and lower bodies in previous literature, PCA results of FFR-specific and traditional anthropometry were inconsistent and insufficient to describe face dimensions with complex anatomy in a small-detailed area, suggesting that facial shape should be understood through a variety of approaches including statistical methods. Logistic regression analysis results confirmed that the association models of FFR-specific face anthropometry were significant with higher prediction accuracy and had a better model's goodness of fit than those of traditional head/face anthropometry in 3 conditions inputting all measurements, all PC scores, or top 5 measurements from PCA. CONCLUSIONS: The findings showed that the FFR fit association model enables an understanding of the detailed association between face and respirator fit and allows for the development of a system to predict respirator fit success or failure based on facial dimensions. Future research would include testing the validity of the model and FFR-specific measurement set on different respirator types, expanding the population set, and developing an integrated approach using automated and machine learning technologies to inform FFR selection for occupation workers and the general population.
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Exposición Profesional , Dispositivos de Protección Respiratoria , Humanos , Cara/anatomía & histología , Diseño de Equipo , AntropometríaRESUMEN
OBJECTIVE: Long-term assessments of lower leg muscle forces in ambulant patients with distal myopathies. METHODS AND MATERIALS: Over a five-year period, we measured involuntary, nerve-stimulated, isometric torques of the ankle dorsiflexors in a group of ambulant patients with myopathies and compared results with voluntary Manual Muscle Tests (MMT). RESULTS: From ten recruited patients, five could finish the five-year protocol. Twenty-seven force measurements sessions (one per year; 1,5 hours duration each) were performed. These patients exhibited low, stable torques or increased minimally (0.2 Newtonmeter, versus 0.1 Nm, ns; 0.7 vs. 1.0, ns; 3.4 vs. 3.5, ns; 0.2 vs. 0.1, ns; 0.8 vs. 1.5, P 0.0004 initial values vs. 5-year values, [norm: 3.9-5.7 Nm]). A 6th patient, eliciting low torque values (0.1 Nm) early passed away. Contraction times inversely correlated with MMT. MMT provided similar overall force abilities. CONCLUSIONS: Long-term monitoring of lower leg muscle forces in ambulant patients is limited by the patient's health status. In a small group of patients, stimulated lower leg forces did not worsen over many years relative to their diagnosed myopathies. Tracking involuntary forces, could be a useful monitoring providing phenotypic information, in addition to MMT. Future devices should be small and be simply self-applying, designed for subjects' domestic use and web-based data transfer. CLINICALTRIALS: gov NCT00735384.
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Músculo Esquelético , Torque , Humanos , Masculino , Músculo Esquelético/fisiología , Músculo Esquelético/fisiopatología , Persona de Mediana Edad , Femenino , Adulto , Enfermedades Musculares/fisiopatología , Estudios de Seguimiento , Pierna/fisiopatología , Pierna/fisiología , Contracción Isométrica/fisiología , Fuerza Muscular/fisiología , Anciano , Contracción Muscular/fisiologíaRESUMEN
STUDY DESIGN: In vitro comparative, laboratory experiments. OBJECTIVE: This study developed a laboratory apparatus that measured resistance to failure using pressures similar to intradiscal pressure of a lumbar spinal disk. Various combinations of an anular repair device were compared. SUMMARY OF BACKGROUND CONTEXT: Herniated material of the intervertebral disk is removed during a lumbar discectomy; however, the defect in the anulus fibrosus remains and can provide a pathway for future herniation. Repairing the anulus fibrosus could mitigate this reherniation and improve patient outcomes. METHODS: A pneumatic cylinder was used to increase the pressure of a sealed chamber until artificial nucleus pulposus material was expulsed through either a 3-mm circular (diameter) or a 6-mm slit anular defect created in a surrogate anulus fibrosus. Each unrepaired condition was compared with 3 repaired conditions using a commercially available soft tissue repair system. The repaired conditions included: (1) a single tension band; (2) 2 tension bands in a cruciate pattern; or (3) 2 tension bands in a parallel pattern. Maximum pressure at the point of extrusion of the internal chamber material and failure or nonfailure of the repair was measured. RESULTS: Significant differences were detected (P<0.05) in maximum failure pressures for the nonrepaired (control) versus repaired conditions. With 1 or 2 tension bands repairing the circular defect, the maximum failure pressure increased by approximately 76% and 131%, respectively. In addition, the failure pressure for 2 tension bands in either a cruciate or parallel configuration was not different, and was approximately 32% higher (P<0.05) than a single tension band in the case of the circular defect. Similar results were seen for the slit defect, with the exception that no difference between the repaired conditions (ie, single vs. 2 tension bands) was detected. CONCLUSIONS: This laboratory simulation demonstrated that repairing the anulus fibrosus after a discectomy procedure can be beneficial for retaining intradiscal material. The use of 2 tension bands, versus a single tension band, in either a cruciate or parallel configuration may further improve the ability to retain disk material.
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Disco Intervertebral/patología , Modelos Biológicos , Estrés Mecánico , Suturas , Cicatrización de Heridas , Discectomía , Humanos , Desplazamiento del Disco Intervertebral , Laboratorios , Vértebras Lumbares , PresiónRESUMEN
Intended for medical students studying the evaluation and diagnosis of heart arrhythmias, the beating heart arrhythmia simulator combines visual, auditory, and tactile stimuli to enhance the student's retention of the subtle differences between various conditions of the heart necessary for diagnosis. Unlike existing heart arrhythmia simulators, our simulator is low cost and easily deployable in the classroom setting. A design consisting of solenoid actuators, a silicon heart model, and a graphical user interface has been developed and prototyped. Future design development and conceptual validation is necessary prior to deployment.
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Cardiología/educación , Instrucción por Computador/instrumentación , Educación Médica Continua/métodos , Corazón Artificial , Corazón/fisiología , Modelos Biológicos , Interfaz Usuario-Computador , Simulación por Computador , Frecuencia Cardíaca/fisiología , Humanos , MiniaturizaciónRESUMEN
BACKGROUND: Three-dimensional printing is an additive manufacturing method that builds objects from digitally generated computational models. Core technologies behind three-dimensional printing are evolving rapidly with major advances in materials, resolution, and speed that enable greater realism and higher accuracy. These improvements have led to novel applications of these processes in the medical field. METHODS: The process of going from a medical image data set (computed tomography, magnetic resonance imaging, ultrasound) to a physical three-dimensional print includes several steps that are described. Medical images originate from Digital Imaging and Communications in Medicine files or data sets, the current standard for storing and transmitting medical images. Via Digital Imaging and Communications in Medicine manipulation software packages, a segmentation process, and manual intervention by an expert user, three-dimensional digital and printed models can be constructed in great detail. RESULTS: Cardiovascular medicine is one of the fastest growing applications for medical three-dimensional printing. The technology is more frequently being used for patient and clinician education, preprocedural planning, and medical device design and prototyping. We report on three case studies, describing how our three-dimensional printing has contributed to the care of cardiac patients at the University of Minnesota. CONCLUSION: Medical applications of computational three-dimensional modeling and printing are already extensive and growing rapidly and are routinely used for visualizing complex anatomies from patient imaging files to plan surgeries and create surgical simulators. Studies are needed to determine whether three-dimensional printed models are cost effective and can consistently improve clinical outcomes before they become part of routine clinical practice.
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Procedimientos Quirúrgicos Cardíacos , Corazón/diagnóstico por imagen , Medicina de Precisión , Impresión Tridimensional , Dextrocardia , Humanos , Gemelos SiamesesRESUMEN
OBJECTIVE: To compare 2 telerehabilitation training strategies, repetitive tracking movements versus repetitive simple movements, to promote brain reorganization and recovery of hand function. METHODS: Twenty subjects with chronic stroke and 10 degrees of voluntary finger extension were randomly assigned to receive 1800 telerehabilitation trials over 2 weeks of either computerized tracking training (track group) with the affected finger and wrist involving temporospatial processing to achieve accuracy or movement training (move group) with no attention to accuracy. Following movement training, the move group crossed over to receive an additional 2 weeks of tracking training. Behavioral changes were measured with the Box and Block test, Jebsen Taylor test, and finger range of motion, along with a finger-tracking activation paradigm during fMRI. RESULTS: The track group showed significant improvement in all 4 behavioral tests; the move group improved in the Box and Block and Jebsen Taylor tests. The improvement for the track group in the Box and Block and Jebsen Taylor tests did not surpass that for the move group. A consistent group pattern of brain reorganization was not evident. The move group, after crossing over, did not show further significant improvements. CONCLUSION: Telerehabilitation may be effective in improving performance in subjects with chronic stroke. Tracking training with reinforcement to enhance learning, however, did not produce a clear advantage over the same amount of practice of random movements. Two weeks of training may be insufficient to demonstrate a behavioral advantage and associated brain reorganization.
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Corteza Motora/fisiología , Plasticidad Neuronal/fisiología , Modalidades de Fisioterapia/instrumentación , Rehabilitación de Accidente Cerebrovascular , Accidente Cerebrovascular/fisiopatología , Telemedicina/métodos , Anciano , Estudios Cruzados , Femenino , Dedos/fisiología , Lateralidad Funcional/fisiología , Humanos , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Desempeño Psicomotor/fisiología , Corteza Somatosensorial/fisiología , Terapia Asistida por ComputadorRESUMEN
BACKGROUND: technical feasibility was evaluated for conducting standard motor assessment instruments in a remote setting. Remote assessment was compared to co-located assessment for five clinical evaluation instruments: joint range-of-motion (ROM), manual muscle test (MMT), Berg sit-to-stand, Berg forward reach, and timed up and go (TUG). METHODS: co-located and remote rooms were in the same building connected by broadband video and audio. Ten subjects without impairments participated, but were given simulated impairments to mimic the patient population commonly seen in rehabilitation clinics. One therapist performed all co-located testing while another performed all remote assessments. Measurements followed standard clinical methods. Data were analyzed using repeated measures ANOVA and paired t-tests. RESULTS: no differences were found between co-located and remote assessments except for some cases using screen-based ROM measures. Remote ROM tests using snapshots and a virtual goniometer were preferred. A digital dynamometer added no additional information to a visually-based remote MMT assessment.
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Diagnóstico por Computador/métodos , Terapia por Ejercicio/métodos , Trastornos del Movimiento/diagnóstico , Trastornos del Movimiento/rehabilitación , Análisis y Desempeño de Tareas , Telemedicina/métodos , Terapia Asistida por Computador/métodos , Interfaz Usuario-Computador , Adolescente , Adulto , Estudios de Factibilidad , Femenino , Humanos , Masculino , Proyectos PilotoRESUMEN
This study analyzed the relationship between electrophysiological responses to transcranial magnetic stimulation (TMS), finger tracking accuracy, and volume of neural substrate in children with congenital hemiparesis. Nineteen participants demonstrating an ipsilesional motor-evoked potential (MEP) were compared with eleven participants showing an absent ipsilesional MEP response. Comparisons of finger tracking accuracy from the affected and less affected hands and ipsilesional/contralesional (I/C) volume ratio for the primary motor cortex (M1) and posterior limb of internal capsule (PLIC) were done using two-sample t-tests. Participants showing an ipsilesional MEP response demonstrated superior tracking performance from the less affected hand (p=0.016) and significantly higher I/C volume ratios for M1 (p=0.028) and PLIC (p=0.005) compared to participants without an ipsilesional MEP response. Group differences in finger tracking accuracy from the affected hand were not significant. These results highlight differentiating factors amongst children with congenital hemiparesis showing contrasting MEP responses: less affected hand performance and preserved M1 and PLIC volume. Along with MEP status, these factors pose important clinical implications in pediatric stroke rehabilitation. These findings may also reflect competitive developmental processes associated with the preservation of affected hand function at the expense of some function in the less affected hand.
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Encéfalo/patología , Potenciales Evocados Motores/fisiología , Dedos/fisiopatología , Cápsula Interna/fisiopatología , Corteza Motora/fisiopatología , Paresia/fisiopatología , Adolescente , Niño , Femenino , Dedos/fisiología , Lateralidad Funcional , Mano/fisiología , Mano/fisiopatología , Humanos , Cápsula Interna/patología , Imagen por Resonancia Magnética , Masculino , Corteza Motora/patología , Paresia/congénito , Paresia/patología , Paresia/rehabilitación , Estimulación Magnética TranscranealRESUMEN
A new design is proposed for an energy storing orthosis (ESO) that restores walking to people with spinal cord injury by combining functional electrical stimulation of the quadriceps muscle with a mechanical brace that uses elastic elements to store and transfer energy between hip and knee joints. The new ESO is a variation of a previous design and uses constant force springs for energy storage. Based on the detailed design and on dynamic simulations, the concept has demonstrated preliminary technical feasibility.
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Tirantes , Estimulación Eléctrica/instrumentación , Marcha/fisiología , Articulación de la Cadera/fisiopatología , Articulación de la Rodilla/fisiopatología , Traumatismos de la Médula Espinal/rehabilitación , Adulto , Diseño de Equipo , Humanos , Masculino , CaminataRESUMEN
Small-scale hydraulics is ideal for powered human assistive devices including powered ankle foot orthoses because a large torque can be generated with an actuator that is small and light. A portable hydraulic ankle foot orthosis has been designed and is undergoing preliminary prototyping and engineering bench test evaluation. The device provides 90 Nm of ankle torque and has an operating pressure of 138 bar (2,000 psi). The battery-operated hydraulic power supply weighs about 3 kg and is worn at the waist. The ankle component weighs about 1.2 Kg and connects to the power supply with two hoses. Performance simulation and preliminary bench testing suggests that the device could be useful in certain rehabilitation applications.
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Tobillo/fisiología , Ortesis del Pié , Pie/fisiología , Diseño de Prótesis , Fenómenos Biomecánicos , Simulación por Computador , Suministros de Energía Eléctrica , Marcha , Humanos , PresiónRESUMEN
ICU patients typically are given large amounts of fluid and often develop oedema. The purpose of this study was to evaluate whether the oedema would change inter-electrode resistance and, thus, require a different approach to using non-invasive electrical stimulation of nerves to assess muscle force. Inter-electrode tissue resistance in the lower leg was measured by applying a 300 µs constant current pulse and measuring the current through and voltage across the stimulating electrodes. The protocol was administered to nine ICU patients with oedema, eight surgical patients without oedema and eight healthy controls. No significant difference in inter-electrode resistance was found between the three groups. For all groups, resistance decreased as stimulation current increased. In conclusion, inter-electrode resistance in ICU patients with severe oedema is the same as the resistance in regular surgical patients and healthy controls. This means that non-invasive nerve stimulation devices do not need to be designed to accommodate different resistances when used with oedema patients; however, surface stimulation does require higher current levels with oedema patients because of the increased distance between the skin surface and the targeted nerve or muscle.
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Edema/fisiopatología , Extremidad Inferior/inervación , Sepsis/fisiopatología , Estimulación Eléctrica Transcutánea del Nervio , Adulto , Anciano , Anciano de 80 o más Años , Edema/patología , Estimulación Eléctrica , Electrodos , Femenino , Humanos , Extremidad Inferior/patología , Extremidad Inferior/fisiología , Masculino , Persona de Mediana Edad , Sepsis/patologíaRESUMEN
BACKGROUND: Gold standards of data analysis for single-case research do not currently exist. OBJECTIVE: The purpose of this study was to determine whether a combined statistical analysis method is more effective in assessing movement training effects in a patient with cerebellar stroke. DESIGN: A crossover single-case research design was conducted. METHODS: The patient was a 69-year-old man with a chronic cerebellar infarct who received two 5-week phases of finger tracking training at different movement rates. Changes were measured with the Box and Block Test, the Jebsen-Taylor test, the finger extension force test, and the corticospinal excitability test. Both visual analysis and statistical tests (including split-middle line method, t test, confidence interval, and effect size) were used to assess potential intervention effects. RESULTS: The results of the t tests were highly consistent with the confidence interval tests, but less consistent with the split-middle line method. Most results produced medium to large effect sizes. LIMITATIONS: The possibility of an incomplete washout effect was a confounding factor in the current analyses. CONCLUSIONS: The combined statistical analysis method may assist researchers in assessing intervention effects in single-case stroke rehabilitation studies.
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Infarto Encefálico/rehabilitación , Enfermedades Cerebelosas/rehabilitación , Técnicas de Ejercicio con Movimientos/métodos , Infarto/rehabilitación , Tonsila Palatina/irrigación sanguínea , Estadística como Asunto/métodos , Rehabilitación de Accidente Cerebrovascular , Anciano , Infarto Encefálico/fisiopatología , Enfermedades Cerebelosas/fisiopatología , Electromiografía , Humanos , Masculino , Tractos Piramidales/fisiopatología , Proyectos de Investigación , Accidente Cerebrovascular/fisiopatologíaRESUMEN
BACKGROUND: Telerehabilitation allows rehabilitative training to continue remotely after discharge from acute care and can include complex tasks known to create rich conditions for neural change. OBJECTIVES: The purposes of this study were: (1) to explore the feasibility of using telerehabilitation to improve ankle dorsiflexion during the swing phase of gait in people with stroke and (2) to compare complex versus simple movements of the ankle in promoting behavioral change and brain reorganization. DESIGN: This study was a pilot randomized controlled trial. SETTING: Training was done in the participant's home. Testing was done in separate research labs involving functional magnetic resonance imaging (fMRI) and multi-camera gait analysis. PATIENTS: Sixteen participants with chronic stroke and impaired ankle dorsiflexion were assigned randomly to receive 4 weeks of telerehabilitation of the paretic ankle. INTERVENTION: Participants received either computerized complex movement training (track group) or simple movement training (move group). MEASUREMENTS: Behavioral changes were measured with the 10-m walk test and gait analysis using a motion capture system. Brain reorganization was measured with ankle tracking during fMRI. RESULTS: Dorsiflexion during gait was significantly larger in the track group compared with the move group. For fMRI, although the volume, percent volume, and intensity of cortical activation failed to show significant changes, the frequency count of the number of participants showing an increase versus a decrease in these values from pretest to posttest measurements was significantly different between the 2 groups, with the track group decreasing and the move group increasing. LIMITATIONS: Limitations of this study were that no follow-up test was conducted and that a small sample size was used. CONCLUSIONS: The results suggest that telerehabilitation, emphasizing complex task training with the paretic limb, is feasible and can be effective in promoting further dorsiflexion in people with chronic stroke.
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Articulación del Tobillo/fisiopatología , Mapeo Encefálico/métodos , Trastornos Neurológicos de la Marcha/fisiopatología , Trastornos Neurológicos de la Marcha/rehabilitación , Rehabilitación de Accidente Cerebrovascular , Accidente Cerebrovascular/fisiopatología , Terapia Asistida por Computador/instrumentación , Adulto , Anciano , Estudios de Factibilidad , Femenino , Humanos , Procesamiento de Imagen Asistido por Computador , Imagenología Tridimensional , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Proyectos Piloto , Programas Informáticos , Estadísticas no ParamétricasRESUMEN
Innovative technological advancements in the field of orthotics, such as portable powered orthotic systems, could create new treatment modalities to improve the functional out come of rehabilitation. In this article, we present a novel portable powered ankle-foot orthosis (PPAFO) to provide untethered assistance during gait. The PPAFO provides both plantar flexor and dorsiflexor torque assistance by way of a bidirectional pneumatic rotary actuator. The system uses a portable pneumatic power source (compressed carbon dioxide bottle) and embedded electronics to control the actuation of the foot. We collected pilot experimental data from one impaired and three nondisabled subjects to demonstrate design functionality. The impaired subject had bilateral impairment of the lower legs due to cauda equina syndrome. We found that data from nondisabled walkers demonstrated the PPAFO's capability to provide correctly timed plantar flexor and dorsiflexor assistance during gait. Reduced activation of the tibialis anterior during stance and swing was also seen during assisted nondisabled walking trials. An increase in the vertical ground reaction force during the second half of stance was present during assisted trials for the impaired subject. Data from nondisabled walkers demonstrated functionality, and data from an impaired walker demonstrated the ability to provide functional plantar flexor assistance.
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Prueba de Esfuerzo/instrumentación , Marcha , Desplazamiento del Disco Intervertebral/complicaciones , Aparatos Ortopédicos , Polirradiculopatía/rehabilitación , Caminata , Adulto , Tobillo , Pie , Marcha/fisiología , Humanos , Masculino , Polirradiculopatía/etiología , Adulto JovenRESUMEN
This paper proposes a new configuration for a hybrid-FES gait restoration system, and presents a combination of simulation and experiment that support the feasibility of the proposed approach. Gait simulation results are presented that indicate the majority of load bearing and the majority of power for gait is provided by the legs (i.e., quadriceps muscle stimulation). Based on these simulations, experiments on healthy subjects indicate that the gait restoration approach should be capable of providing long periods of locomotion unimpeded by quadriceps muscle fatigue.
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Terapia por Estimulación Eléctrica/instrumentación , Marcha/fisiología , Aparatos Ortopédicos , Paraplejía/rehabilitación , Caminata/fisiología , Simulación por Computador , Diseño de Equipo , Articulación de la Cadera/fisiología , Humanos , Articulación de la Rodilla/fisiología , Modelos Biológicos , Músculo Esquelético/fisiologíaRESUMEN
OBJECTIVES: To compare 4 ureteral occlusion devices in terms of insertion force, maneuverability, radial dilation and extraction forces, ability to prevent stone migration, and tip stiffness. METHODS: The devices tested were the PercSys Accordion, Microvasive Stone Cone (7 and 10 mm), and Cook N-Trap. Using a ureteral model with an artificial stone in place, the insertion force, number of attempts, and time to pass the impacted stone were measured. Using a Teflon block model, radial dilation and extraction and axial extraction force were measured with a load cell. Holmium lithotripsy was performed in the ureteral model with a canine stone in place to test the ability of the devices to prevent stone migration. In a similar model, the force applied to retrieve the canine stone was measured. The stiffness of the tip was measured as the force to compress a 5-mm length of the tip in a clamp-clamp configuration on a linear motion stage driven by a stepper motor with a resolution of 8-mum/step. RESULTS: The devices were significantly different statistically from each other in terms of insertion force, number of attempts and time to pass the impacted stone, radial dilation, radial extraction, and axial extraction force in the Teflon block model. No proximal migration of the stones occurred with any of the devices. The devices were similar in terms of preventing proximal stone migration, force applied to retrieve stones, and tip stiffness. CONCLUSIONS: The differences in the physical characteristics of stone migration devices might help to predict their safety and efficacy in clinical use.
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Migración de Cuerpo Extraño/prevención & control , Cálculos Renales/terapia , Litotripsia por Láser/instrumentación , Cálculos Ureterales/terapia , Animales , Modelos Animales de Enfermedad , Perros , Diseño de Equipo , Seguridad de Equipos , Litotripsia por Láser/métodos , Ensayo de Materiales , Sensibilidad y Especificidad , Estrés Mecánico , Obstrucción Ureteral/terapia , UreteroscopíaRESUMEN
OBJECTIVE: To evaluate physical characteristics of next-generation access sheaths that impact clinical failure. METHODS: Testing of the Cook Flexor (12/14 Fr x 35 cm, Cook), ACMI UroPass (12/14 Fr x 38 cm, ACMI), Bard Aquaguide (11/13 Fr x 35 cm Bard), and Boston Scientific Navigator (11/13 Fr x 36 cm BSCI-11, 13/15 Fr x 36 cm BSCI-13) was performed on a linear motion stage driven by a stepper motor with a resolution of 5 microm per step. Force was measured at a sampling rate of 5 Hz with a Wagner FDIX digital force gauge. Friction force was measured by pulling sheaths at 2.5 mm/s through 2.78 mm (8.3 Fr) holes drilled in 36 mm thick biologic material. Buckling force was measured as the force required to compress a 25-cm length of sheath in a clamp-clamp configuration during a 30 mm move. Kinking was measured as the slope of the force-deflection curve for wall compression over a deflection of 2 mm. RESULTS: No significant difference was noted in the friction force of the Cook (1.2 N), Bard (1.3 N), BSCI-11 (1.0 N), and BSCI-13 (1.0 N). Buckling force was significantly greater for the Cook (5.1 +/- 0.49 N) than the Bard (2.8 +/- 0.31 N), BSCI-11 (2.0 +/- 0.25 N), ACMI (3.2 +/- 0.33 N), and BSCI-13 (2.9 +/- 0.31 N). Kinking force was significantly lower with the Bard (9 N/mm) than the Cook (42 N/mm), BSCI-11 (41 N/mm), and BSCI-13 (30 N/mm), and significantly higher with the ACMI (83 N/mm). CONCLUSIONS: The Cook Flexor sheath is most resistant to buckling forces that would predict failure to advance up the ureter. The Bard Aquaglide is most likely to kink after removal of the inner obturator, whereas the ACMI Uropass is most resistant to kinking.
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Ureteroscopios , Fuerza Compresiva , Diseño de Equipo , Falla de Equipo , Fricción , Ensayo de MaterialesRESUMEN
The purpose of this project was to determine if the properties of doublet force twitches change with recruitment level. Isometric, human tibialis anterior force twitches were measured in response to singlet and doublet stimulation at several recruitment levels for eight healthy subjects. All doublets showed nonlinear force summation. When normalized to singlet responses at the equivalent recruitment level, doublet peak force, torque-time integral, half pulse width and half decay time changed with recruitment while start time and contraction time did not. Although the number of subjects was small, the results suggest that caution must be exercised when extending doublet properties at full recruitment to partial recruitment conditions.