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1.
Neuroimage ; 103: 163-170, 2014 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-25255049

RESUMEN

Several investigations have shown limitations of fMRI reliability with the current standard field strengths. Improvement is expected from ultra highfield systems but studies on possible benefits for cognitive networks are lacking. Here we provide an initial investigation on a prominent and clinically highly-relevant cognitive function: language processing in individual brains. 26 patients evaluated for presurgical language localization were investigated with a standardized overt language fMRI paradigm on both 3T and 7T MR scanners. During data acquisition and analysis we made particular efforts to minimize effects not related to static magnetic field strength differences. Six measures relevant for functional activation showed a large dissociation between essential language network nodes: although in Wernicke's area 5/6 measures indicated a benefit of ultra highfield, in Broca's area no comparison was significant. The most important reason for this discrepancy was identified as being an increase in susceptibility-related artifacts in inferior frontal brain areas at ultra high field. We conclude that functional UHF benefits are evident, however these depend crucially on the brain region investigated and the ability to control local artifacts.


Asunto(s)
Mapeo Encefálico/métodos , Encéfalo/fisiología , Comprensión/fisiología , Imagen por Resonancia Magnética/métodos , Adolescente , Adulto , Anciano , Niño , Femenino , Humanos , Procesamiento de Imagen Asistido por Computador , Lenguaje , Masculino , Persona de Mediana Edad , Adulto Joven
2.
J Phys Condens Matter ; 24(25): 256004, 2012 Jun 27.
Artículo en Inglés | MEDLINE | ID: mdl-22634874

RESUMEN

The magnetic properties of amorphous Fe-Ni-B based metallic glass nanostructures were investigated. The nanostructures underwent a spin-glass transition at temperatures below 100 K and revealed an irreversible temperature following the linear de Almeida-Thouless dependence. When the nanostructures were cooled below 25 K in a magnetic field, they exhibited an exchange bias effect with enhanced coercivity. The observed onset of exchange bias is associated with the coexistence of the spin-glass phase along with the appearance of another spin-glass phase formed by oxidation of the structurally disordered surface layer, displaying a distinct training effect and cooling field dependence. The latter showed a maximum in exchange bias field and coercivity, which is probably due to competing multiple equivalent spin configurations at the boundary between the two spin-glass phases.

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