Detalles de la búsqueda
1.
Safety and efficacy of the miR-124 upregulator ABX464 (obefazimod, 50 and 100 mg per day) in patients with active rheumatoid arthritis and inadequate response to methotrexate and/or anti-TNFα therapy: a placebo-controlled phase II study.
Ann Rheum Dis
; 2022 May 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-35641124
2.
Safety, Pharmacokinetics, and Antiviral Activity of a Novel HIV Antiviral, ABX464, in Treatment-Naive HIV-Infected Subjects in a Phase 2 Randomized, Controlled Study.
Antimicrob Agents Chemother
; 61(7)2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28507108
3.
Randomized Trial of Food Effect on Pharmacokinetic Parameters of ABX464 Administered Orally to Healthy Male Subjects.
Antimicrob Agents Chemother
; 61(1)2017 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27799203
4.
Pharmacokinetics and tolerability of ABX464, a novel first-in-class compound to treat HIV infection, in healthy HIV-uninfected subjects.
J Antimicrob Chemother
; 72(3): 820-828, 2017 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27999038
5.
Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions.
J Immunol
; 195(5): 2343-52, 2015 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26209628
6.
Small peptides blocking inhibition of factor Xa and tissue factor-factor VIIa by tissue factor pathway inhibitor (TFPI).
J Biol Chem
; 289(3): 1732-41, 2014 Jan 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-24275667
7.
Safety and immunogenicity of a vero cell culture-derived whole-virus influenza A(H5N1) vaccine in a pediatric population.
J Infect Dis
; 209(1): 12-23, 2014 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24041789
8.
Hyperimmune intravenous immunoglobulin containing high titers of pandemic H1N1 hemagglutinin and neuraminidase antibodies provides dose-dependent protection against lethal virus challenge in SCID mice.
Virol J
; 11: 70, 2014 Apr 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-24739285
9.
Neutralization of macrophage migration inhibitory factor (MIF) by fully human antibodies correlates with their specificity for the ß-sheet structure of MIF.
J Biol Chem
; 287(10): 7446-55, 2012 Mar 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-22238348
10.
A vero cell-derived whole-virus H5N1 vaccine effectively induces neuraminidase-inhibiting antibodies.
J Infect Dis
; 205(1): 28-34, 2012 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22090447
11.
ABX464 (Obefazimod) Upregulates miR-124 to Reduce Proinflammatory Markers in Inflammatory Bowel Diseases.
Clin Transl Gastroenterol
; 14(4): e00560, 2023 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36573890
12.
ABX464 (obefazimod) for patients with COVID-19 at risk for severe disease: miR-AGE, a randomized, double-blind placebo-controlled trial.
J Allergy Clin Immunol Glob
; 2(4): 100140, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37781656
13.
Obefazimod: A First-in-class Drug for the Treatment of Ulcerative Colitis.
J Crohns Colitis
; 17(10): 1689-1697, 2023 Nov 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37129565
14.
A cell culture-derived influenza vaccine provides consistent protection against infection and reduces the duration and severity of disease in infected individuals.
Clin Infect Dis
; 54(7): 946-54, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22267715
15.
Efficacy, safety, and immunogenicity of a Vero-cell-culture-derived trivalent influenza vaccine: a multicentre, double-blind, randomised, placebo-controlled trial.
Lancet
; 377(9767): 751-9, 2011 Feb 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-21329971
16.
Preparation of commercial quantities of a hyperimmune human intravenous immunoglobulin preparation against an emerging infectious disease: the example of pandemic H1N1 influenza.
Transfusion
; 52(4): 803-9, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-21981280
17.
A tick-borne encephalitis virus vaccine based on the European prototype strain induces broadly reactive cross-neutralizing antibodies in humans.
J Infect Dis
; 203(11): 1556-64, 2011 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21592984
18.
Demonstration of the Antitumor Activity of the iNKT Agonist ABX196, a Novel Enhancer of Cancer Immunotherapy, in Melanoma and Hepatocarcinoma Mouse Models.
Mol Cancer Ther
; 21(12): 1788-1797, 2022 12 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36198025
19.
ABX464 (obefazimod) for moderate-to-severe, active ulcerative colitis: a phase 2b, double-blind, randomised, placebo-controlled induction trial and 48 week, open-label extension.
Lancet Gastroenterol Hepatol
; 7(11): 1024-1035, 2022 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36075249
20.
A clinical trial of a whole-virus H5N1 vaccine derived from cell culture.
N Engl J Med
; 358(24): 2573-84, 2008 Jun 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-18550874