RESUMEN
BACKGROUND: Sensitization to acrylates is a concern in the occupational/environmental dermatology field. OBJECTIVE: To describe an occupational allergic contact dermatitis (ACD) outbreak from a smartphone screen protector glue. METHODS: Thirteen affected workers of a chain store selling phone screen protectors were investigated in five Spanish dermatology departments. The glue datasheet and label were assessed. A chemical analysis of the glue was performed. Based on this, some patients underwent additional testing. RESULTS: All patients (all female, mean age: 25) had severe fingertip dermatitis. The datasheet/label indicated that the glue contained isobornyl acrylate (IBOA), a "photoinitiator" and polyurethane oligomer. The company informed us that the ingredients were polyurethane acrylate, "methacrylate" (unspecified), acrylic acid, hydroxyethyl methacrylate, propylmethoxy siloxane, and photoinitiator 184. Isobornyl acrylate (or IBOA) and N,N-dimethylacrylamide (DMAA) were patch tested in eight and two cases, respectively, with negative results. A chemical analysis revealed 4-acryloylmorpholine (ACMO); isobornyl methacrylate (IBMA), and lauryl acrylate in one glue sample. Seven patients were patch tested with dilutions of the identified substances and six of seven were positive for ACMO 0.5% pet. CONCLUSION: An outbreak of occupational ACD, likely from ACMO in a glue is described. Further investigations are needed to corroborate the role played by each compound identified in the chemical analyses.
Asunto(s)
Dermatitis Alérgica por Contacto , Dermatitis Profesional , Acrilatos/efectos adversos , Adulto , Dermatitis Alérgica por Contacto/diagnóstico , Dermatitis Alérgica por Contacto/epidemiología , Dermatitis Alérgica por Contacto/etiología , Dermatitis Profesional/diagnóstico , Dermatitis Profesional/epidemiología , Dermatitis Profesional/etiología , Brotes de Enfermedades , Femenino , Humanos , Pruebas del Parche , Poliuretanos , Teléfono InteligenteRESUMEN
Progressive macular hypomelanosis (PMH) is a condition of unknown etiology characterized by asymptomatic, hypopigmented macules located predominantly on the trunk. We recorded 12 adolescents with PMH over a 6-month period. Ten were female, and the mean age was 16.6 years. The average time from the patients first noticing pigment change to diagnosis was 15 months. PMH is probably an underdiagnosed condition.
Asunto(s)
Abdomen , Dermis/patología , Hipopigmentación/patología , Región Lumbosacra , Adolescente , Biopsia , Diagnóstico Diferencial , Progresión de la Enfermedad , Femenino , Humanos , MasculinoRESUMEN
Se presenta el caso clínico de un paciente con calcinosis cutis distrófica en glúteo, una pa- tología infrecuente e infra-diagnosticada por la falta de sospecha clínica. Es de vital importancia que a quienes presenten calcificaciones cutáneas se les realice una detallada anamnesis y un estudio analítico con función renal, metabolismo del calcio y fósforo y autoinmunidad para descartar la existencia de una patología subyacente como las enfermedades autoinmunes o renales..(AU)
We present the clinical case of a patient with calcinosis dystrophic skin on the buttock, an infre- quent and infradiagnosed pathology due to the lack of clinical suspicion. It is very important that those patients with skin calcifications have a detalied anamnesis and analytical study with renal function, calcium and phosphrus metabolism and autoinmmunity to rule out the existence of un- derlying pathology such an autoimmune or renal diseases..(AU)
Asunto(s)
Nalgas , CalcinosisAsunto(s)
Dermatitis Herpetiforme/patología , Autoanticuerpos/inmunología , Autoantígenos/inmunología , Biopsia , Terapia Combinada , Dapsona/uso terapéutico , Dermatitis Herpetiforme/diagnóstico , Dermatitis Herpetiforme/inmunología , Dermatitis Herpetiforme/terapia , Dieta Sin Gluten , Técnica del Anticuerpo Fluorescente Indirecta , Humanos , Inmunoglobulina A/inmunología , Masculino , Persona de Mediana Edad , Transglutaminasas/inmunologíaAsunto(s)
Pustulosis Exantematosa Generalizada Aguda/diagnóstico , Fiebre/etiología , Pustulosis Exantematosa Generalizada Aguda/complicaciones , Pustulosis Exantematosa Generalizada Aguda/tratamiento farmacológico , Azitromicina/administración & dosificación , Azitromicina/uso terapéutico , Diagnóstico Diferencial , Quimioterapia Combinada , Femenino , Humanos , Leucocitosis/etiología , Persona de Mediana Edad , Prednisona/administración & dosificación , Prednisona/uso terapéutico , Psoriasis/diagnósticoRESUMEN
La mononucleosis infecciosa debe sospecharse en pacientes que cursan un cuadro pseudogripal que evoluciona a una faringoamigdalitis inespecífica y aparición de lesiones cutáneas, que frecuentemente se confunde con una infección bacteriana. Su expresión en la piel da lugar a dos tipos de exantemas. El primero, de aparición temprana, polimorfo y que resuelve en pocos días y otro, llamado sinérgico, relacionado con la administración de antibióticos. Presentamos el caso de una paciente con mononucleosis infecciosa que desarrolló un exantema de tipo sinérgico.
Infectious mononucleosis should be suspected in patients who have flu-like symptoms which progress to nonspecific pharyngitis and skin lesions. It is usually confused with a bacterial infection. Expression in the skin gives rise to two types of exanthemas. The first one, early-onset, polymorphous and early-resolution. The other one, also called synergic, related to antibiotics. We report a case of a patient with an infectious mononucleosis and a synergic exanthema.