Corticosteroid injection of the arthritic hip: what is the indication?

Forty-four patients who had image-guided corticosteroid injection of the hip were reviewed as part of a service improvement project to ascertain the medium term benefit of the procedure. Injections were indicated for treatment of hip pain or as part of a diagnostic work up to differentiate hip from back pain. At 42-month review, 39 patients fulfilled the criteria for the study. Of those having therapeutic injections, 70% had gone on to hip replacement, while only 20% of those having diagnostic injections had done so. These results suggest that, for patients who are fit for surgery, hip replacement should be the intervention of choice as corticosteroid injection does not substantially delay the need for surgery. Where there is doubt about the source of pain, there seems to be a clear role for diagnostic injection.

Reliability and validity of the acquired brain injury challenge assessment (ABI-CA) in children.

PRIMARY OBJECTIVE: The Acquired Brain Injury Challenge Assessment (ABI-CA) was created to fill a measurement gap and evaluate deficits in advanced motor skills in children with acquired brain injury (ABI). Study objectives were to refine ABI-CA response options and evaluate (i) inter-/intra-rater reliability, (ii) concurrent validity and difficulty level in relation to the Community Balance & Mobility Scale (CB&M) and (iii) administration efficiency of the refined ABI-CA. RESEARCH DESIGN: Measurement study. METHODS: Phase I involved ABI-CA revisions. Phase 2 consisted of live-/video-scoring of the ABI-CA with 15 typically-developing (TD) children and 15 with ABI (7-17 years) to assess reliability/validity. RESULTS: The revised 20-item ABI-CA displayed excellent reliability for the entire sample (ICCs > 0.90; 95% CI = 0.92-1.00; SEM ≤ 3.60) and within ABI and TD sub-groups. The ABI-CA and CB&M correlated strongly (r = 0.75, p < 0.0001). The ABI-CA mean score (/100) was 11.3 points lower (p < 0.0001) than the CB&M's mean score (/100). CONCLUSION: The ABI-CA demonstrated excellent reliability and initial evidence of validity. ABI-CA scores were lower overall than the CB&M, indicating the ABI-CA may have greater capacity to evaluate improvements in advanced motor skills in children with ABI. Multi-centre research is needed to confirm the ABI-CA's test-retest reliability and, assuming acceptability, assess responsiveness to change.

Wet or dry bandages for plaster back-slabs?

Cotton crêpe and stretch bandages are commonly used in back-slabs and casts in orthopaedic practice. In theory they allow swelling to occur after injury while splinting the fracture. The application of a wet bandage prevents the Plaster-of-Paris (POP) setting too rapidly, giving time to apply a mould or attain correct limb position. However, we hypothesised that a wet bandage contracts upon drying and may cause constriction of the splint. This study aimed at determining whether there was any significant change in length of commonly used bandages when wet as well as any further change when left to dry again. Two types of bandage were evaluated. 250 mm strips of bandage were dipped into water, gently squeezed and laid flat on a bench. The bandage was then immediately measured in length. The strips were then left to dry and re-measured. This experimental study shows that both cotton crepe and cling significantly shrink by around 7% when wet. This phenomenon has the potential to significantly increase the pressure exerted on the limb by a back-slab. We speculate that the application of wet bandages is why some back-slabs may need released. It is therefore recommended that bandages should be applied only in the dry form.

Use of radiology by general practitioners making orthopaedic referrals: a cross-sectional study.

BACKGROUND: In orthopaedic clinics, patients can be x-rayed during their visit to the surgeon. Could radiographs carried out in primary care be more efficiently carried out when the patient meets the surgeon? AIMS: To quantify and describe use of radiological investigations by general practitioners (GPs), when referring to orthopaedics. METHODS: We made a retrospective examination of 294 referral letters for detail regarding x-ray investigation of the condition prompting the letter. We used referral letters assessed by the recipient as 'routine'. We excluded those addressed to a particular surgeon because of subspecialty interest or prior care. RESULTS: Twenty one percent (62) of referrals described an investigation that did not contribute to management prior to the patient's clinic appointment. CONCLUSIONS: A significant number of patients travelled specifically for an x-ray. In some of these cases the radiographs could be delayed until the clinic visit without compromising care. DISCUSSION: We suggest that GPs seeing patients with musculoskeletal problems should consider referral to an orthopaedic surgeon prior to requesting x-rays. X-ray investigation in the orthopaedic clinic may be more convenient for the patient and surgeon.

Peri-operative radiation exposure: Are overweight patients at increased risks?

The aim of this study was to identify if there was a correlation between body mass index (BMI) and intra-operative radiation exposure. A retrospective review of 81 patients who had sliding hip screw fixation for femoral neck fractures in one year was completed, recording body mass index (BMI), screening time, dose area product (DAP), American Society of Anesthesiologists (ASA) grade, seniority of operating surgeon and complexity of the fracture configuration. There was a statistically significant correlation between dose area product and BMI. There was no statistically significant relationship between screening time and BMI. There was no statistical difference between ASA grade, seniority of surgeon, or complexity of fracture configuration and dose area product. Simulated stochastic risks were increased for overweight patients. Overweight patients are exposed to increased doses of radiation regardless of length of screening time. Surgeons and theatre staff should be aware of the increased radiation exposure during fixation of fractures in overweight patients and, along with radiographers, ensure steps are taken to minimise these risks. Whilst such radiation dosages may have little adverse effect for individual patients, these findings may be of more relevance and concern to staff that will be exposed to increased radiation.

Paradoxical response of plasma lipoprotein(a) in patients undergoing cardiopulmonary bypass.

Plasma lipid, lipoprotein and apolipoprotein levels are known to decrease after major surgery. Coronary artery bypass surgery additionally involves use of extracorporeal circulation by use of a cardiopulmonary bypass pump, which necessitates hemodilution due to saline dextrose infusion to prime the pump. To investigate changes in lipids, lipoproteins and apolipoproteins as well as changes in C-reactive protein and albumin we conducted a study on 22 patients undergoing cardiac surgery involving cardiopulmonary bypass. Timed arterial blood samples were taken before, during and after cardiopulmonary bypass. At the onset and during cardiopulmonary bypass a rapid and significant fall was observed in all lipids and lipoproteins except lipoprotein(a) with recovery to near basal levels by 72 h for cholesterol, triglycerides, high density lipoprotein cholesterol and albumin, while apolipoproteins AI and B remained below basal levels during the postoperative period up to 72 h. In contrast, lipoprotein(a) levels increased at the onset, doubled during cardiopulmonary bypass and remained elevated postoperatively. On the other hand, C-reactive protein levels fell at the onset and during cardiopulmonary bypass but they became markedly elevated postoperatively. When results were corrected for hemodilution, the response patterns remained unchanged. As lipoprotein(a) is both atherogenic and thrombogenic, its elevation during cardiopulmonary bypass may be clinically important.

Increased whole blood viscosity during coronary artery bypass surgery. Studies to evaluate the effects of soluble fibrin and poloxamer 188.

This study was designed to test the hypothesis that soluble fibrin complexes resulting from the trauma of surgery could produce elevated blood viscosity, to characterize the soluble fibrin polymers, and to evaluate in vitro the effect of a new hemorheologic agent, poloxamer 188, on viscosity in these abnormal situations. Ten patients undergoing aortocoronary bypass surgery were studied before and at various times after surgery. By 6 h after surgery, the mean hematocrit decreased by 23%, fibrinogen decreased 48%, and erythrocyte sedimentation rate decreased 33%, whole blood viscosity at a low shear rate rose on average of 69% and soluble fibrin rose 118%. Over the 6-day observation period, the concentrations of soluble fibrin paralleled the changes in viscosity, whereas the concentrations of fibrinogen varied nearly inversely with viscosity. The effects of various forms of fibrinogen and fibrin were tested by additions to normal blood. Soluble fibrin polymers, but not fibrin monomers, increased blood viscosity two to three fold. Poloxamer 188 reduced the viscosity of all patient samples to the normal range. These data support the hypothesis that increased whole blood viscosity at low shear rates is caused by hydrophobic adhesion of fibrin polymers to red cells and that poloxamer 188 normalizes viscosity by effectively disrupting the weak hydrophobic bonds.

Effect of positive end-expiratory pressure on excessive mediastinal bleeding after cardiac operations. A controlled study.

The efficacy of mechanical ventilation with positive end-expiratory pressure (PEEP) in the therapy of excessive mediastinal hemorrhage following cardiac operations remains unproved. One hundred thirty-nine patients undergoing elective myocardial revascularization were divided into two groups on the basis of preoperative hematologic evaluation: Group I, 94 patients with no history of hematologic abnormalities and a normal coagulation profile; Group II, 45 patients with a recent use of antiplatelet medications and/or a prolonged template bleeding time. Both groups were randomized to receive mechanical ventilation with 10 cm H2O of PEEP or no PEEP beginning 1 hour after operation and continuing for an 8 hour study period. Mean blood loss at 8 hours (BVt) was not significantly different between PEEP and control patients in either group. Fifty-seven patients in Groups I and II had mediastinal bleeding in excess of 180 ml/hr at the initiation of the study period. There was no significant difference in mean BVt or mean hourly chest tube output with or without PEEP in either group of this subset. In view of the lack of demonstrable efficacy in decreasing mediastinal hemorrhage and the potential of adverse hemodynamic effects, PEEP should no longer be used for therapy of excessive bleeding after cardiac operation, especially in patients with reduced cardiac reserve.

Intraoperative hemodialysis during cardiopulmonary bypass in chronic renal failure.

This report describes the features and the course of a patient on maintenance hemodialysis in whom infective endocarditis of the aortic valve ensued. The subsequent development of intractable congestive heart failure necessitated aortic valve replacement. Use of intraoperative hemodialysis, facilitating the intraoperative and postoperative management of the patient, is described. Following valve replacement the patient did well with no evidence of congestive heart failure.

Incidence of Cell-Saver contamination during cardiopulmonary bypass.

During regular bacteriological surveillance of cardiac surgical equipment and patients, the Cell Saver apparatus (CSA) was prospectively evaluated to determine if it represented an additional risk for infection. Nineteen patients were studied. After each operation, the effluent from the CSA was sterilely sealed for subsequent culture. A total of 42 aerobic and 42 anaerobic cultures were made. Postoperatively all patients were evaluated daily for four days and before discharge for clinical evidence of infection. Four patients had positive CSA cultures without evidence of postoperative clinical infection. Five patients in whom postoperative infectious complications developed had negative CSA cultures. Ten patients had negative CSA cultures and no evidence of postoperative infection. We conclude that the CSA does not appear to contribute to the risk of infection in cardiac surgical patients and that it is a safe adjunct to cardiac surgery.

Open-heart surgery in Jehovah's Witnesses: experience in a Canadian hospital.

Jehovah's Witnesses have religious belief precluding the use of blood. Few centers have attempted open-heart surgery bound by such strictures; as a result, availability of therapy for such patients has been limited. Many groups that have extensive experience with hemodilution for cardiopulmonary bypass have noted that these procedures can often be done with little or no use of blood. Our experience with 21 adult patients is presented in this paper.

Gentamicin solution for mediastinal irrigation: systemic absorption, bactericidal activity, and toxicity.

Local irrigation with gentamicin sulfate represents a possible substitute for neomycin sulfate, used for many years but now no longer available for use as an irrigation fluid. In this investigation, mediastinal irrigation with gentamicin was used in 12 patients who had experienced problems after a heart operation. The regimen employed for mediastinal irrigation with gentamicin was equipotent with that using neomycin. We sought to determine the degree of absorption and risk of either inadequate or toxic blood levels that might follow gentamicin absorption. Irrigation periods were short, ranging from one to four days and determined by measurements of plasma gentamicin concentration using radioimmunoassay evaluation. Systemic gentamicin absorption occurred in all patients. Toxic levels of higher than 8.0 micrograms/mL occurred and were size related, ie, correlated with smaller body weight and surface area, and sex related, ie, female sex. Larger-sized patients often had inadequate levels. Despite the potential risk from toxic blood levels, major increases in serum creatinine levels were not seen. These findings suggest that monitoring of plasma gentamicin levels during mediastinal irrigation with gentamicin is mandatory to avoid both inadequate treatment and toxicity.

A concept of illness tested as an improved basis for surgical decisions in low-back disorders.

In previous studies a model of illness based on analysis of the relationship between the different elements of illness at one pont in time was developed. This study prospectively tested this model and a number of associated hypotheses in 185 patients who had various types of surgery for low-back disorders: 49 had chemonucleolysis; 91, first-time disc operations; 20, fusions; and 25, repeat operations. Identical pre- and postoperative evaluations were performed with 96% of patients independently reviewed at an average of 26 months after surgery. The authors analyzed how physical and psychologic factors interacted to affect the outcome of surgery and attempted to explain other conflicting reports of how either physical or psychologic factors determined surgical outcome. It was found that physical outcome was almost entirely determined by physical factors, ie, accuracy of diagnosis of a surgically treatable lesion, operative findings, surgical procedure, and avoidance of complications. The most important psychologic disturbances were distress and abnormal illness behavior that could affect surgical outcome indirectly if inappropriate illness behavior led to inappropriate surgery and also directly affected subjective judgments of pain or disability--by patient or observer. Return to work was strongly influenced by additional occupational factors. All the main hypotheses were confirmed and this model or concept of illness is proposed as the basis for a fundamental reconsideration of clinical management and surgical decisions in low-back disorders.

Acetabular reconstruction with a bipolar prosthesis. Five year results of the Dautry technique.

We report the results of acetabular reconstruction using a bipolar prosthesis bearing on cancellous bone graft in 37 patients after a minimum of five years. There was a satisfactory clinical outcome in 58% when assessed by pain, range of movement and stability, with greater improvement in the pain score than of the other parameters. Radiological migration of the prosthesis was a frequent finding although this did not always correlate with symptoms. Better results were obtained in cases of primary or secondary protrusio acetabuli than after the revision of previous total arthroplasties.

The long-term results of the Howse total hip arthroplasty. With particular reference to those requiring revision.

We present the results of 506 consecutive Howse hip arthroplasties with a minimum follow-up of 10 years. The mortality within one month of surgery was 0.79%. The early dislocation rate was 1.38%, two hips requiring revision. Nine hips developed deep sepsis (1.78%), eight of which required revision. At 10 years 42 hips (8.3%) had required revision, including 14 with aseptic acetabular loosening and 11 with femoral stem fractures. We feel that as judged by the dislocation rate and the need for subsequent revision, the Howse arthroplasty is an acceptable form of total hip replacement, particularly in the older patient and in those requiring total replacement for femoral neck fractures.

Assessment of the outcome of low back surgery.

We aimed to develop a better understanding and method of rating the success or failure of low back surgery by studying 185 patients prospectively. Identical pre-operative and postoperative assessment by an independent observer included pain, disability, physical impairment, psychological distress and illness behaviour. Outcome was assessed by the patient, by the observer and by return to work. There was 96% follow-up at two years. Correlation co-efficients varied considerably between the various measures of outcome, both patient and observer appearing to base their assessment mainly on postoperative status rather than on any change produced by surgery. The observer was influenced most by postoperative pain, disability and physical impairment. Patients were influenced most by residual physical impairment, type of surgery and proportional change in disability. Return to work was moderately influenced by postoperative disability and to a larger extent by social and work-related factors. We developed a simple formula to judge overall success or failure which accurately reproduced the combined assessment of patient and observer. If surgical audit is to be meaningful it must be based on an improved understanding of how the outcome of surgery should be assessed.

Urinary bladder/pulmonary artery temperature ratio of less than 1 and shivering in cardiac surgical patients.

BACKGROUND: Temperature gradients that normally exist between body areas may be altered as a result of heat generated by shivering. METHODS AND POPULATION: Two core thermal gradients between pulmonary artery and urinary bladder were compared with shivering in 37 coronary artery bypass graft patients. Pulmonary artery and urinary temperature were measured every 15 minutes, and shivering was evaluated electromyographically. RESULTS: Shivering developed in 28 patients (76%). With shivering the pulmonary artery/urinary bladder temperature ratio was less than 1 but in the nonshivering group was greater than 1. Correlation (r value) between pulmonary artery and urinary temperature ranged from 0.93 to 0.99. Rate pressure product was higher in the shivering group than in the nonshivering group. A pulmonary artery/urinary bladder temperature ratio of less than 1 was seen with shivering in this subset of patients. CONCLUSION: Pulmonary artery and urinary bladder temperatures are readily available clinically. The combination of a ratio of less than 1 and an increase in rate pressure product should be considered suggestive of shivering in coronary artery bypass graft patients.

Relationship between urinary bladder and pulmonary artery temperatures: a preliminary study.

"Core" temperature and the proper methods for its assessment and management in cardiac surgical patients with hypothermia continues to be a concern for physicians and nurses. In this study we investigated the relationship between pulmonary artery and urinary bladder temperatures over a 6-hour period during rewarming in 14 (adult) patients in the intensive care unit after cardiopulmonary bypass. Bladder temperatures were 0.1 degree C to 0.2 degree C higher than pulmonary artery temperature with correlation coefficients of 0.94 to 0.99. This relationship continued for most of this period with significant mean differences clustering in the early and late period after admission. The significance of these small differences of temperatures and why the two temperatures reversed at certain time periods needs further investigation because the normal thermal gradients may be altered by the hypermetabolic activities consequent to shivering or iatrogenic overheating.

Closed rupture of flexor pollicis longus tendon associated with treatment of Bennett's fracture.

A case of closed rupture of the tendon of flexor pollicis longus following treatment of a Bennett's fracture is described. This unusual complication was treated by transfer of the tendon of flexor digitorum superficialis of the ring finger.

Liver function in a group of hospitalised alcoholics and non-hospitalised problem drinking probationers.

Twenty non-hospitalised problem male drinkers and 20 hospitalised problem drinkers were investigated by the Michigan alcohol screening test (MAST) and by liver function tests (AST, ALT). The MAST scores of the non-hospitalised group were above normal and indicative of alcohol addiction, AST and ALT tended to be higher in the hospitalised but not indicative of severe liver damage.