Trends for in-office usage of pharmacological sedation agents in India: A narrative review.

Background and Aims: Conscious sedation plays a significant role in in-office pharmacological behavior management for short-term procedures in children and apprehensive adults. The advantage conscious sedation provides is by improving quality of care provided by decreasing pain and anxiety while maintaining a patent airway and adequate spontaneous ventilation. Methodology: Present review was conducted to evaluate recent trends regarding use of in-office pharmacological sedation agents in India. A rigorous search was conducted through five electronic databases namely PubMed, Scopus, Web of Science, Cochrane Database, and CTRI (Clinical Trial Registry - India). The search period was defined to be last 5 years, that is, from 1st January 2014 to 31st July 2019. Terminologies "Conscious Sedation," "In-office Sedation," "Midazolam," "Nitrous Oxide," "India" were included in the search. The Boolean Operation "OR" and "AND" were applied to combine the terminologies. Results: A total of 20 studies were identified following strict inclusion and exclusion criteria. The included studies were evaluated for study design, speciality involved, number of individuals and their age groups, drugs compared along with route and dosage, procedures undertaken, place of study and results. Dental fraternity (13) had more number of trials conducted as compared to medical fraternity (7) in the stimulated period, with South Indian region having maximum trials registered or published. Conclusion: Midazolam was observed to the drug of choice for in-office sedation procedures in Indian Scenario. The limitation of study is that the published clinical studies are limited to a few states of India.

Split-mouth Randomised Clinical Trial on the Efficacy of GIC Sealant on Occlusal Surfaces of Primary Second Molar.

PURPOSE: To evaluate the clinical performance of high viscosity GIC sealant applied with or without additional light curing in children with early childhood caries (ECC). MATERIALS AND METHODS: A split-mouth clinical trial was conducted in a total of 111 3- to 5-year-old children with ECC. 180 pairs of non-carious primary second molars were selected and divided into two groups: study and control. On the basis of the application technique, selected teeth in the study group were further allotted to group A (sealant application with additional light curing) and group B (sealant application without additional light curing). Caries incidence was observed for 1 year in the anatomical pits and grooves, along with sealant retention and marginal discolouration at various intervals over the 1-year period. RESULTS: Group A (GIC sealant with additional light curing) (44.2%) showed sealant retention similar to that of group B (GIC sealant without additional light curing) (43.0%) (p = 0.885). Caries incidence was significantly higher in the control group (26%) than the sealant groups (1%) (p < 0.001). No marginal discolouration adjacent to the sealant was observed in either anatomical grooves or pits in both sealant groups for the duration of the study. CONCLUSION: Retention and caries prevention by high-viscosity GIC sealant applied with or without additional light curing was found to be similar. At the 12-month assessment, mean dmfs scores and caries incidence in primary second molars were higher in the control than in both study groups.

Transmission of mutans streptococci in mother-child pairs.

BACKGROUND & OBJECTIVES: Dental caries is an infectious, transmissible disease. Maternal transfer of mutans streptococci (MS) has been a subject of research. The aim of this study was to evaluate the transmission of MS from mother to children through genetic analysis. METHODS: Thirty mother-child pairs were included and divided into three groups according to the age of the children. Saliva samples were collected and MS colonies from each mother-child pair were isolated. After inoculation and incubation, MS colonies were submitted to amplification technique by polymerase chain reaction (PCR) for identification and arbitrarily primed PCRs (AP-PCRs) to determine various MS genotypes. RESULTS: From birth to six months of age, 30 per cent of children exhibited MS colonization, and by the age of 30 months, 100 per cent harboured the bacteria (P < 0.001). Factors associated with MS colonization were eruption of teeth (P < 0.001), feeding habits with mean colony count being significantly lower in breast-fed as compared to bottle-fed children (P < 0.001) and a significant association between mean MS count of child and mother's practice of sharing spoon with child (P < 0.001). The AP-PCR fingerprinting profile analysis showed 17 MS groups (clusters) containing identical or highly related isolates in mother-child pairs with a high level of similarity (77.27 %). INTERPRETATION & CONCLUSIONS: The presence of matching MS genotypes suggested vertical transmission from mothers to children. Feeding habits, gum cleaning and number of erupted teeth in children had significant effect on MS colonization. There is a need to develop strategies to present MS colonization in children.

Minimally invasive bone-saving orbitotomy for removal of optic nerve cysticercosis.

A 32-year-old man previously being managed for multiple neurocysticercosis presented with a reduction in vision and pain on eye movement. Fundus examination revealed disc edema with venous dilatation. MRI showed a localized hypointensity on T1 weighted images and hyperintensity on T2 weighted images suggestive of a cyst in the optic nerve sheath. Medical therapy with albendazole and steroids did not improve vision. Surgical removal of the cyst was achieved by a modified lateral orbital exploration using a lateral canthal incision without bone removal, with full recovery of vision. Histopathological examination confirmed cysticercosis.

Esthetic management of developmental enamel opacities in young permanent maxillary incisors with two microabrasion techniques--a split mouth study.

PURPOSE: This study evaluated the effectiveness of two microabrasion materials for the removal of developmental enamel opacities in young permanent maxillary incisors. MATERIALS AND METHODS: Using a split-mouth study design, 37% phosphoric acid and 18% hydrochloric acid were used for removal of visually unesthetic developmental enamel opacities of young permanent maxillary anterior teeth from 25 subjects (11-13 years old) by two microabrasion techniques for 10 and 5 seconds respectively. This procedure was repeated four to six times during each clinical appointment. The subjects were evaluated about their satisfaction with the treatment. Two blinded evaluators appraised both sides of the mouth using visual analog scale. The records were analyzed using Wilcoxon test. RESULTS: The majority of the subjects (approximately 97%) reported satisfaction at the end of the treatment (p = 0.001**). Statistical significant reduction in enamel opacities was observed by evaluators immediately after microabrasion technique in group 1 (81.75%) and in group 2 (81.4%) (p < 0.002). Reduction was increased to 97.2% in group 1 and 96.7% in group 2 after 1 month. CONCLUSIONS: Both microabrasion techniques showed comparative highly significant successful results in esthetic management of enamel opacities clinically and in terms of subject's satisfaction. CLINICAL SIGNIFICANCE: Developmental enamel defects like diffuse opacities due to high-fluoride content in water and demarcated opacities associated with positive dental history and are commonly seen in young permanent maxillary incisors of both boys and girls in their developing years. They are aware of unesthetic appearance of these newly erupted permanent anterior teeth and become highly motivated when informed about minimally invasive, patient friendly, cost-effective, and safe treatment like microabrasion for esthetic improvement. Both noninvasive microabrasion techniques using 37% phosphoric acid (group 1) and 18% hydrochloric acid (group 2) show comparatively high success results in treating enamel defects successfully to the subject's satisfaction along with their parents.

Minimal invasive transcaruncular optic canal decompression for traumatic optic neuropathy.

Traumatic optic neuropathy is a cause of loss of vision associated with head injuries. Treatment options include observation, steroids and decompression of the optic canal. We report a case where the optic canal decompression was performed using a transcaruncular approach under a regional block. The incision was made through the caruncle and the dissection was carried down to the periosteum down to the orbital apex where the optic nerve was seen exiting through the optic canal posterior to the posterior ethmoidal artery. The optic nerve was decompressed with good visualization. Hemostasis and wound closure was achieved using fibrin glue. Postoperatively visual acuity improved with minimal inflammation enabling early rehabilitation.

Perceptual Learning for Rehabilitation in Traumatic Optic Neuropathy.

Traumatic optic neuropathy is a cause of sudden irreversible visual loss due to optic nerve damage following trauma. Reports of improvement have been noted after observation alone, treatment with corticosteroids, and surgical decompression. However, final visual acuity may not be predictable, with individual patients having little improvement in visual function despite therapy. Perceptual learning improves visual functions by improving the neural processing so as to allow image perception at low signal-to-noise ratios. The case report describes the beneficial effect of perceptual learning in traumatic optic neuropathy, the first to describe the use of perceptual learning in an optic neuropathy. A larger case-controlled study of the effect of perceptual learning in optic neuropathies is required to substantiate the beneficial effect and elaborate the scale of improvement that may be possible with this form of therapy.

Optic Canal Decompression and Direct Ophthalmic Artery Fibrinolysis for Traumatic Optic Neuropathy With Central Retinal Artery Occlusion.

Central retinal artery occlusion is a rare association of traumatic optic neuropathy. Superselective fibrinolytic therapy is a management option for central artery occlusion that reduces systemic side effects of thrombolysis. A rare case of posttraumatic central retinal artery occlusion is described where optic nerve decompression was performed followed by restoration of central retinal flow by direct puncture of ophthalmic artery and institution of fibrinolytic therapy.

Management of Root Fractures in Young Immature Permanent Teeth: Three Case Reports.

Aim: The aim of this case report is to present three different patients who had horizontal and vertical root fractures of young permanent teeth, its diagnosis, clinical and radiographic findings, treatment, and long-term follow-up and success rate. Background: Root fractures are relatively rare with the prevalence of 0.5-7% in permanent and 2-4% in deciduous dentition. Timely intervention and accurate treatment procedures are the main concerns for long-term success of root fractures. Case description: Case I and case II had horizontal fracture of immature permanent tooth. Patients reported with a chief complaint of pain in their upper central incisors. As a result of radiographic examination, horizontal root fractures were diagnosed. Teeth were treated with a mineral trioxide aggregate (MTA) plug (case I and case II) and repositioning and splinting (case II). Case III had vertical root fracture of immature permanent tooth. Tooth was treated with apexification (sectional obturation) and sealed with resin-modified glass ionomer cement (RMGIC) till the fracture site and flowable light cure restoration. Patients were scheduled for follow-up visits at different time intervals. Radiographic evidence indicated ongoing root development in these immature teeth. Normal color and mobility were observed, and no pain was noted during horizontal and vertical percussion tests. Conclusion: The present case report shows a favorable and stable outcome of timely treatment and sound healing of various types of root fracture. Long-term follow-up of patients with trauma is essential because pathological changes can occur several years following injury. Clinical significance: The latest treatment modalities and long-term follow-up showed clinical success. How to cite this article: Dhindsa A, Garg S, Poddar P, et al. Management of Root Fractures in Young Immature Permanent Teeth: Three Case Reports. Int J Clin Pediatr Dent 2024;17(3):352-356.

Gender differences in pathways influencing leisure time physical activity: A structural equation analysis.

BACKGROUND AND AIMS: Growing interest in exploring pathways that explain the relationship between various influences on physical activity might help in explaining the complexity of this behavior. This study attempts to identify pathways that interact between the physical and social environment and leisure-time physical activity and identify gender differences in these pathways. METHODS: A survey was conducted in the Kottayam district of Kerala in India from July 2018-December 2019 to examine direct and indirect pathways of various factors that impact leisure-time physical activity. 467 adults in the age group of 18-65 years, was enquired about various individual and environmental factors that affect their physical activity levels. Structural equation modeling was employed to test the relationship among different variables. RESULTS: The study found that there was a significant indirect effect of intrapersonal and environmental influences in the pathways that affected leisure-time physical activity. Among men, there was a significant association between self-efficacy and motivation and environmental influences (environmental factors, p = 0.019; body-related motivation p = 0.012, motivation for social motives reasons, p = 0.005); however, among women, environmental factors influence only through extrinsic motives related to body image and appearance (environmental factors, p = 0.009, motivation for appearance, p = 0.05). CONCLUSION: The study concludes that although intrapersonal factors like self-efficacy and extrinsic motives like health and fitness are salient predictors of physical activity, environmental factors play a supportive role in enhancing engagement in leisure time activity. Future interventions should be tailored to meet gender-specific interests to promote regular physical activity among adults.

Acute Kidney Injury Following Naphthalene (Mothball) Poisoning.

Naphthalene is a widely available moth repellant in the Asian subcontinent. Toxicity can occur either accidentally or intentionally as a suicide attempt. An overdose can lead to a variety of clinical symptoms, including intravascular hemolysis, and can sometimes lead to life-threatening clinical situations. A young male was admitted to our center with an alleged history of ingesting an unknown quantity of naphthalene balls (mothballs). He developed methemoglobinemia, intra-vascular hemolysis, anuria, and acute kidney injury (AKI), followed by cardiorespiratory arrest. He was treated successfully with intravenous methylene blue and dialysis. Naphthalene toxicity can lead to methemoglobinemia and intravascular hemolysis. This can result in AKI caused by pigment nephropathy.

Nonsurgical Management of Drug-induced Gingival Overgrowth in a Young Patient.

Background: Gingival enlargement or gingival overgrowth (GO) is a very common complication of the various classes of drugs and the most common being, the anticonvulsant drug phenytoin (PHT). PHT and its metabolites have a direct effect on the periodontal tissues; with poor oral hygiene also contributing to the severity of inflammation in patients with drug-induced gingival overgrowth (DIGO). Case description: Here we present a case of PHT-induced gingival overgrowth (PGO) in a 12-year-old male patient and discuss the management of the condition. Conclusion: Management of drug-induced overgrowth of gingiva includes strict oral hygiene maintenance practice, meticulous professional care with several adjunctive periodontal therapies like photodynamic therapy and Local drug delivery. Surgical treatment is indicated if the overgrown tissue has become fibrotic. Clinical significance: The pediatric dentist plays an important role in early identification and proper management of the condition by timely intervention and collaboration with other specialists. How to cite this article: Dalal R, Garg S, Gupta A. Nonsurgical Management of Drug-induced Gingival Overgrowth in a Young Patient. Int J Clin Pediatr Dent 2023;16(S-3):S331-S334.

To Evaluate the Success of Natural Compound: Curcumin as Obturating Material in Primary Teeth.

Background: In a quest a search for newer obturating materials, trends have now shifted from more harmful chemical-based compounds to less toxic and more natural Ayurvedic or herbal materials. Curcumin-a natural extract from turmeric rhizomes, possesses anti-inflammatory and antimicrobial properties and thus may be used as a novel obturating material in the primary teeth. Objective: To evaluate and compare the efficacy of curcumin powder mixed with zinc oxide-eugenol (ZOE) and ZOE as obturating materials in primary molars. Materials and methods: A total of 30 primary molars indicated for pulpectomy were selected from 4-8-year-old children and divided into two groups. Group 1-ZOE group included 11 teeth, and in group II, 19 teeth were obturated with-curcumin mixed with ZOE mixed (ZOE + C). The efficacy of these obturation materials was evaluated both clinically and radiographically after 3, 6, and 9 months. Results: At 9 months, there was a significant reduction in preoperative clinical signs and symptoms. Mobility was absent in all the teeth in group I, while 5 teeth presented with mobility in group II after 9 months.On radiographic assessment, at the end of the 9 months, material resorption was similar to physiological root resorption in 40% of teeth in group I and 22.2% in group II. Interradicular radiolucency increased in 66.7% of teeth in group II when compared to 20% of teeth in group I. Pathological root resorption was seen in 10% of roots in the ZOE group and 55.6% of the roots in the ZOE+C group. How to cite this article: Dalal R, Gupta A, Srivastava A, et al. To Evaluate the Success of Natural Compound: Curcumin as Obturating Material in Primary Teeth. Int J Clin Pediatr Dent 2023;16(6):793-799. Conclusion: Despite the well-documented antibacterial and anti-inflammatory properties of curcumin powder in literature, considering the results of the present study we cannot suggest curcumin powder as successful alternative obturation material for treating deciduous teeth.

Study of Developmental Defects of Enamel in Young Permanent Maxillary Incisors in 11-13-year-old Indian Children for Occurrence Distribution and Associated Factors.

Purpose: The aim of present study was to assess the frequency, severity, and distribution of developmental defects of tooth enamel and correlate the etiology with the type of defect in 11-13-year-old Indian children. Materials and methods: The present study included examination of permanent maxillary incisors in 500 children in the age-group of 11-13 years to examine the occurrence of distribution of developmental defects of tooth enamel. Materials and methods: Only the buccal surface of four permanent maxillary incisors was examined for enamel defects using modified developmental defects of enamel (DDE) index by Clarkson which recognized three basic types of enamel defects; namely demarcated opacities, diffuse opacities, and hyploplsia. Personnel details, dental history which included dental infection, extraction, trauma, lifetime fluoride, fluoride in water, and medical history were also recorded. Data was coded and analyzed for distribution of developmental defects of tooth enamel by tooth type and gender using Statistical Package for the Social Sciences. Result: Out of 500, 114 (22.8%) children showed defective enamel in permanent maxillary incisors. Of all enamel defects, diffuse opacities were most prevalent with 48.25% occurrence followed by demarcated opacities 38.5%, hypoplasia 10.52%, and any other defects 1.75%. No significant difference was observed in males and females for the occurrence of developmental enamel defects. The occurrence of dental enamel defect significantly correlated with dental history as well as with medical history (Chi-squared statistical test, p-value = 0.001**). Conclusion: (1) High fluoride in water accounts for most prevalent diffuse opacity. (2) Demarcated opacities are associated mainly with positive dental history. (3) Hypoplasia of incisors was found to be least prevalent associated with trauma, periapical infections. How to cite this article: Sheoran N, Garg S, Dhindsa A, et al. Study of Developmental Defects of Enamel in Young Permanent Maxillary Incisors in 11-13-year-old Indian Children for Occurrence Distribution and Associated Factors. Int J Clin Pediatr Dent 2023;16(S-2):S176-S182.

Exploring the Impact of Al2O3 Additives in Gasoline on HCCI-DI Engine Performance: An Experimental, Neural Network, and Regression Analysis Approach.

This study delves into the influence of incorporating alumina (Al2O3) nanoparticles with waste cooking oil (WCO) biofuels in a gasoline engine that employs premixed fuel. During the suction phase, gasoline blends with atmospheric air homogeneously at the location of the inlet manifold. The biodiesel, enhanced with Al2O3 nanoparticles and derived from WCO, is subsequently directly infused into the combustion chamber at 23° before the top dead center. The results highlight that when gasoline operates in the homogeneous charge compression ignition with direct injection (HCCI-DI) mode, there is a notable enhancement in thermal efficiency by 4.23% in comparison to standard diesel combustion. Incorporating the Al2O3 nanoparticles with the WCO biodiesel contributes to an extra rise of 6.76% in thermal efficiency. Additionally, HCCI-DI combustion paves the way for a reduction in nitrogen oxides and smoke emissions, whereas biodiesel laced with Al2O3 nanoparticles notably reduces hydrocarbon and carbon monoxide discharges. Predictive tools such as artificial neural networks and regression modeling were employed to forecast engine performance variables.

Effect of maternal parenting style on child behaviour and its management strategies in dental office: A pilot study.

AIM: To evaluate the effect of maternal parenting style on child behaviour and consequent management strategies in dental office. MATERIALS AND METHODS: Eighty child-mother pairs were included in the study. Before the start of the treatment, Maternal parenting style was evaluated utilising Primary Caregivers Practices Report, while child behaviour along with his/her perception towards dental treatment were observed using Frankl Behaviour Rating Scale and Sound Eye Motor scale, respectively. Also the behaviour management strategy utilised for the child was noted and its correlation to both parenting style and child behaviour was evaluated. RESULTS: A statistically significant correlation (p-value = 0.00) was observed between the maternal parenting style and child behaviour displayed during dental treatment. Also, a positive correlation (p-value = 0.00) was observed between behaviour displayed by the children and behaviour management strategy used in the dental operatory. CONCLUSION: The clinicians can predict the type of behaviour the child might display and the behaviour management strategy to be utilised for a specific child based on the maternal parenting style.

Impact on Quality of Life and Risk Factors Associated with Visible Maxillary Incisors Trauma among Young Children in Faridabad, Haryana.

Aim: To assess the impact of upper incisor trauma on the quality of life (QoL) in young children studying between the age group 8 and 13 years in Faridabad, Haryana. Materials and methods: A cross-sectional, prospective study was conducted to assess the visible permanent maxillary incisor traumas according to the classification of traumatic dental injuries (TDI) and to determine the predisposing risk factors that affect TDI and their impact on QoL in children aged 8-13 years. Questionnaires were made to gather information on demographic and socioeconomic characteristics like age, gender, and the father's and mother's education. Data on dental caries in anterior teeth were also collected using current World Health Organization criteria. Result: There were a total of 66 males and 24 females. The total decayed, missing, and filled permanent teeth (DMFT) prevalence observed was 8.9%. The main reason for trauma was found to be an accident or accidental fall (36.7%). The most common place for trauma followed by road (21.1%). Time lapsed from the injury reported was >1 year in males (34.8%), while it was within 1 year (41.7%) in females (p = 0.014). The most prevalent and impacted performance was smiling (80.0%; m = 8.7778 ± 8.658), and the least affected was speaking (4.4%; m = 0.5111 ± 3.002). Conclusion: A number of risk factors need to be considered when assessing TDIs, as TDIs can have a negative impact on the functional, social, and psychological well-being of young children. As they are frequent in children, affecting teeth, their supporting structures, and adjacent soft tissues, they may cause both functional and esthetic problems. Clinical significance: When injuries to incisor(s) produce pain, disfigurement, poor aesthetics, or other psychological effects, children may avoid laughing or smiling, and this can affect their social relationships. So, it is important to address the risk factors that predispose upper front teeth to TDIs. How to cite this article: Elizabeth S, Garg S, Saraf BG, et al. Impact on Quality of Life and Risk Factors Associated with Visible Maxillary Incisors Trauma among Young Children in Faridabad, Haryana. Int J Clin Pediatr Dent 2022;15(6):652-659.

Multidisciplinary approach to the rehabilitation of a tooth with two trauma episodes: systematic review and report of a case.

Studies have shown that some children and adolescents are affected only once with dental trauma, while others seem to be accident-prone and suffer from multiple dental trauma episodes. Less is known about treatment consequences related to repeated traumatic dental injuries to the same tooth and treatment guidelines are not well established. Complicated crown fractures and crown-root fractures pose difficulties for dentists to establish adequate treatment plans because these fractures require multidisciplinary knowledge and approach for a correct case planning and prognosis. The objective of this paper was to present and discuss a case of a child who sustained a second trauma to the same tooth following treatment of an earlier sustained crown fracture. The research-based background for establishment of the treatment plan is discussed. Reattachment of tooth fragment is a minimal invasive and esthetic method. Essential advantage of the reattached teeth is the fact that all the alternative methods as direct adhesive resin reconstruction, veneers and crowns can be performed in case of failure or a refracture. As a consequence of initial trauma, the tooth suffered a complicated crown fracture which was resolved by endodontic therapy and fragment reattachment. During follow-up, the child suffered a second trauma resulting in dislodgement and fracture of the reattached fragment and a crown-root fracture extending subgingivally with involvement of the biologic width. A conservative restorative option is described. After 1 year of follow-up, the clinical and radiographic findings demonstrated that the adopted clinical protocol was successful and yielded healthy periodontal tissues with no signs of periradicular pathosis. The occurrence of repeated traumatic dental injuries to teeth involving conservative management of both crown-root fracture and complicated crown fracture on the same tooth is extremely rare and a challenge for dental professionals to treat.

Fear of COVID 19 Infection Across Different Cohorts: A Scoping Review.

Background: Psychological stressors like panic, fear, phobia, etc., are being substantially reported during the COVID-19 outbreak. In the prior outbreaks, fear of being infected was reported as the prominent suicide stressor. Therefore, fear of infection has become a concern in the context of the COVID-19 pandemic because it worsens emotion, cognition, and behavioral responses. Understanding the extent of fear of COVID-19 infection in various cohorts would aid in gauging the mental health services, which was a remedy in the present review. Methods: Adhering to Arksey and O'Malley's framework for conducting a scoping review, a systematic search was performed in the month of September 2020 in several databases, including Scopus, PubMed, Web of Science, etc. Considering the inclusion criteria, a total of 14 articles were included in the present review. Results: All of the included studies were conducted via online platforms, whereas all but one of the studies were cross-sectional in nature (including a mixed-method study, and a comparative study). Most of the studies were conducted among the general population (n = 12), within March and May 2020 (n = 9), from Asian countries (n = 7), and considered a self-developed item for fear of COVID-19 assessment (n = 8; whereas the Fear of COVID-19 Scale was used in 6-studies). The prevalence of fear of COVID-19 was reported to be 18.1-45.2%, although no cutoff point or criteria was mentioned for such a prevalence estimation of the Fear of COVID-19 Scale. However, females, younger adults, urban residents, divorcees, healthcare workers, those in quarantine settings, those in suspicion of being infected, and those with mental health problems, etc., were found to be at an increased risk of COVID-19 fear. Conclusions: Being one of the first reviews in this context, the findings are anticipated to be helpful to predict the possible solutions for reducing fear of COVID-19 and facilitate further studies on strategies of how to alleviate such a stressful situation.

Arch Measurements, Bigonial Width, Dental Caries, and Their Effect on Occurrence of Mandibular Incisors Crowding in Early Mixed Dentition Period.

AIM AND OBJECTIVE: To assess the effect of various arch parameters, bigonial angle, and caries occurrence on mandibular incisors crowding during the early mixed dentition period. MATERIALS AND METHODS: Sixty children (mean age of 7.5 years) with mandibular anterior incisors crowding and class I molar relationship in early mixed dentition were selected. Bigonial width (BW) and caries occurrence were recorded during patient examination. The study casts were prepared divided into a normal group (NG) and crowded group (CG). Different vertical and transverse arch perimeters along with space available for the permanent mandibular incisors were measured manually. Statistical analysis was done to establish the association of all these variables with two crowding groups. RESULTS: The total incisor width or the tooth material was significantly more, and all arch parameters were less in measurements in CG than NG. The available space, BW, and caries occurrence did not differ significantly between NG and CG. CONCLUSION: The amount of tooth material and individual variations in arch parameters significantly contribute to mandibular anterior crowding in the early mixed dentition period irrespective of the age and gender of the child. CLINICAL SIGNIFICANCE: All cases of early mixed dentition mandibular incisors crowding should be individually assessed for arch length discrepancy, and transverse discrepancy results of this study help in the prediction of crowding before an establishment of a customized treatment plan with the use of lingual arch or lip bumper appliances in patients with anterior mandibular crowding may be valuable. HOW TO CITE THIS ARTICLE: Paul S, Garg S, Saraf BG, et al. Arch Measurements, Bigonial Width, Dental Caries, and Their Effect on Occurrence of Mandibular Incisors Crowding in Early Mixed Dentition Period. Int J Clin Pediatr Dent 2021;14(S-1):S57-S62.