RESUMEN
Although most infantile haemangiomas do not require treatment due to a natural history of spontaneous involution, some require early intervention. The Australasian Vascular Anomalies Network and the Australasian Paediatric Dermatology Network have developed a consensus statement for the treatment of infantile haemangiomas with oral propranolol. Infants with haemangiomas that are life threatening, at risk of ulceration, or at risk of causing a significant functional impairment, psychological impact or physical deformity should be treated early with oral propranolol. Oral propranolol is safe and effective and in most healthy infants oral propranolol can be started in an outpatient setting.
Asunto(s)
Consenso , Hemangioma Capilar/tratamiento farmacológico , Síndromes Neoplásicos Hereditarios/tratamiento farmacológico , Propranolol/uso terapéutico , Vasodilatadores/uso terapéutico , Monitoreo de Drogas , Humanos , Selección de Paciente , Propranolol/administración & dosificación , Vasodilatadores/administración & dosificaciónRESUMEN
We describe an unusual case of multidrug-resistant miliary tuberculosis diagnosed 9 months after the commencement of infliximab treatment for psoriasis despite negative pretreatment tuberculosis screening, including chest X-ray and interferon-gamma release assay. After 4 months' treatment with amikacin, ethambutol, pyrazinamide and moxifloxacin, infliximab was restarted with concomitant anti-TB medications. No recurrence of tuberculosis has been detected 12 months after recommencing infliximab.
Asunto(s)
Antiinflamatorios no Esteroideos/efectos adversos , Anticuerpos Monoclonales/efectos adversos , Tuberculosis Latente/diagnóstico , Tuberculosis Miliar/etiología , Tuberculosis Resistente a Múltiples Medicamentos/etiología , Tuberculosis Pulmonar/etiología , Antituberculosos/uso terapéutico , Artritis Psoriásica/tratamiento farmacológico , Reacciones Falso Negativas , Humanos , Infliximab , Ensayos de Liberación de Interferón gamma , Tuberculosis Latente/complicaciones , Masculino , Persona de Mediana Edad , Tuberculosis Miliar/tratamiento farmacológico , Tuberculosis Resistente a Múltiples Medicamentos/tratamiento farmacológico , Tuberculosis Pulmonar/tratamiento farmacológicoRESUMEN
We describe the development of psoriatic nail disease due to metoprolol in a 58-year-old woman who was being treated for cardiac arrhythmias. The nail condition was unresponsive to topical and systemic treatments but resolved completely with the withdrawal of metoprolol. The reaction recurred with drug rechallenge and resolved when the drug was ceased.
Asunto(s)
Antiarrítmicos/efectos adversos , Metoprolol/efectos adversos , Enfermedades de la Uña/inducido químicamente , Psoriasis/inducido químicamente , Femenino , Humanos , Persona de Mediana Edad , Taquicardia Supraventricular/tratamiento farmacológicoRESUMEN
Cutaneous endometriosis that arises de novo, without a prior history of surgery, is a rare phenomenon. The clinical diagnosis of cutaneous endometriosis remains challenging due to the variable clinical appearance and symptoms of the condition, and therefore must be considered in the differential diagnosis of any umbilical lesion. We report a 31-year-old woman who presented with spontaneous cutaneous endometriosis of the umbilicus.