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1.

Extended-Synaptotagmin-1 and -2 control T cell signaling and function.

Benavides, Nathalia; Giraudo, Claudio G.

EMBO Rep ; 25(1): 286-303, 2024 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-38177911

2.

Novel Compound Heterozygous ZAP70 R37G A507T Mutations in Infant with Severe Immunodeficiency.

Benavides, Nathalia; White, Jason C; Sanmillan, Maria L; Thomas, Morgan; Le, Trong; Caywood, Emi; Giraudo, Claudio G.

J Clin Immunol ; 44(1): 27, 2023 12 22.

Artículo en Inglés | MEDLINE | ID: mdl-38129328

3.

SM protein Munc18-2 facilitates transition of Syntaxin 11-mediated lipid mixing to complete fusion for T-lymphocyte cytotoxicity.

Spessott, Waldo A; Sanmillan, Maria L; McCormick, Margaret E; Kulkarni, Vineet V; Giraudo, Claudio G.

Proc Natl Acad Sci U S A ; 114(11): E2176-E2185, 2017 03 14.

Artículo en Inglés | MEDLINE | ID: mdl-28265073

4.

Syntaxin 4 mediates endosome recycling for lytic granule exocytosis in cytotoxic T-lymphocytes.

Spessott, Waldo A; Sanmillan, Maria L; Kulkarni, Vineet V; McCormick, Margaret E; Giraudo, Claudio G.

Traffic ; 18(7): 442-452, 2017 07.

Artículo en Inglés | MEDLINE | ID: mdl-28471021

5.

RHOG: Rac1-ing up another HLH gene.

Nichols, Kim E; Giraudo, Claudio G.

Blood ; 137(15): 1990-1991, 2021 04 15.

Artículo en Inglés | MEDLINE | ID: mdl-33856445

6.

Hemophagocytic lymphohistiocytosis caused by dominant-negative mutations in STXBP2 that inhibit SNARE-mediated membrane fusion.

Spessott, Waldo A; Sanmillan, Maria L; McCormick, Margaret E; Patel, Nishant; Villanueva, Joyce; Zhang, Kejian; Nichols, Kim E; Giraudo, Claudio G.

Blood ; 125(10): 1566-77, 2015 Mar 05.

Artículo en Inglés | MEDLINE | ID: mdl-25564401

7.

Apoptotic vesicles ameliorate lupus and arthritis via phosphatidylserine-mediated modulation of T cell receptor signaling.

Wang, Runci; Hao, Meng; Kou, Xiaoxing; Sui, Bingdong; Sanmillan, Maria Laura; Zhang, Xiao; Liu, Dawei; Tian, Jun; Yu, Wenjing; Chen, Chider; Yang, Ruili; Sun, Lingyun; Liu, Yi; Giraudo, Claudio; Rao, Deepak A; Shen, Nan; Shi, Songtao.

Bioact Mater ; 25: 472-484, 2023 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-37056273

8.

Identification of a site in Sar1 involved in the interaction with the cytoplasmic tail of glycolipid glycosyltransferases.

Quintero, Cristián A; Giraudo, Claudio G; Villarreal, Marcos; Montich, Guillermo; Maccioni, Hugo J F.

J Biol Chem ; 285(39): 30340-6, 2010 Sep 24.

Artículo en Inglés | MEDLINE | ID: mdl-20650895

9.

Colonoids From Patients With Pediatric Inflammatory Bowel Disease Exhibit Decreased Growth Associated With Inflammation Severity and Durable Upregulation of Antigen Presentation Genes.

Kelsen, Judith R; Dawany, Noor; Conrad, Maire A; Karakasheva, Tatiana A; Maurer, Kelly; Wei, Jane M; Uman, Selen; Dent, Maiah H; Behera, Rithika; Bryant, Laura M; Ma, Xianghui; Moreira, Leticia; Chatterji, Priya; Shraim, Rawan; Merz, Audrey; Mizuno, Rei; Simon, Lauren A; Muir, Amanda B; Giraudo, Claudio; Behrens, Edward M; Whelan, Kelly A; Devoto, Marcella; Russo, Pierre A; Andres, Sarah F; Sullivan, Kathleen E; Hamilton, Kathryn E.

Inflamm Bowel Dis ; 27(2): 256-267, 2021 01 19.

Artículo en Inglés | MEDLINE | ID: mdl-32556182

10.

Variants in STXBP3 are Associated with Very Early Onset Inflammatory Bowel Disease, Bilateral Sensorineural Hearing Loss and Immune Dysregulation.

Ouahed, Jodie; Kelsen, Judith R; Spessott, Waldo A; Kooshesh, Kameron; Sanmillan, Maria L; Dawany, Noor; Sullivan, Kathleen E; Hamilton, Kathryn E; Slowik, Voytek; Nejentsev, Sergey; Neves, João Farela; Flores, Helena; Chung, Wendy K; Wilson, Ashley; Anyane-Yeboa, Kwame; Wou, Karen; Jain, Preti; Field, Michael; Tollefson, Sophia; Dent, Maiah H; Li, Dalin; Naito, Takeo; McGovern, Dermot P B; Kwong, Andrew C; Taliaferro, Faith; Ordovas-Montanes, Jose; Horwitz, Bruce H; Kotlarz, Daniel; Klein, Christoph; Evans, Jonathan; Dorsey, Jill; Warner, Neil; Elkadri, Abdul; Muise, Aleixo M; Goldsmith, Jeffrey; Thompson, Benjamin; Engelhardt, Karin R; Cant, Andrew J; Hambleton, Sophie; Barclay, Andrew; Toth-Petroczy, Agnes; Vuzman, Dana; Carmichael, Nikkola; Bodea, Corneliu; Cassa, Christopher A; Devoto, Marcella; Maas, Richard L; Behrens, Edward M; Giraudo, Claudio G; Snapper, Scott B.

J Crohns Colitis ; 15(11): 1908-1919, 2021 Nov 08.

Artículo en Inglés | MEDLINE | ID: mdl-33891011

11.

SNAREs can promote complete fusion and hemifusion as alternative outcomes.

Giraudo, Claudio G; Hu, Chuan; You, Daoqi; Slovic, Avram M; Mosharov, Eugene V; Sulzer, David; Melia, Thomas J; Rothman, James E.

J Cell Biol ; 170(2): 249-60, 2005 Jul 18.

Artículo en Inglés | MEDLINE | ID: mdl-16027221

12.

STXBP2-R190C Variant in a Patient With Neonatal Hemophagocytic Lymphohistiocytosis (HLH) and G6PD Deficiency Reveals a Critical Role of STXBP2 Domain 2 on Granule Exocytosis.

Benavides, Nathalia; Spessott, Waldo A; Sanmillan, Maria L; Vargas, Marcelo; Livingston, Mylynda S; Erickson, Nissa; Pozos, Tamara C; McCormick, Margaret E; Scharrig, Emilia; Messinger, Yoav H; Giraudo, Claudio G.

Front Immunol ; 11: 545414, 2020.

Artículo en Inglés | MEDLINE | ID: mdl-33162974

13.

The Fas/Fap-1/Cav-1 complex regulates IL-1RA secretion in mesenchymal stem cells to accelerate wound healing.

Kou, Xiaoxing; Xu, Xingtian; Chen, Chider; Sanmillan, Maria Laura; Cai, Tao; Zhou, Yanheng; Giraudo, Claudio; Le, Anh; Shi, Songtao.

Sci Transl Med ; 10(432)2018 03 14.

Artículo en Inglés | MEDLINE | ID: mdl-29540618

14.

Endoplasmic reticulum export of glycosyltransferases depends on interaction of a cytoplasmic dibasic motif with Sar1.

Giraudo, Claudio G; Maccioni, Hugo J F.

Mol Biol Cell ; 14(9): 3753-66, 2003 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-12972562

15.

Ganglioside glycosyltransferases and newly synthesized gangliosides are excluded from detergent-insoluble complexes of Golgi membranes.

Crespo, Pilar M; Zurita, Adolfo R; Giraudo, Claudio G; Maccioni, Hugo J F; Daniotti, Jose L.

Biochem J ; 377(Pt 3): 561-8, 2004 Feb 01.

Artículo en Inglés | MEDLINE | ID: mdl-14565845

16.

Endogenous species of mammalian nonmuscle myosin IIA and IIB include activated monomers and heteropolymers.

Shutova, Maria S; Spessott, Waldo A; Giraudo, Claudio G; Svitkina, Tatyana.

Curr Biol ; 24(17): 1958-68, 2014 Sep 08.

Artículo en Inglés | MEDLINE | ID: mdl-25131674

17.

Dual roles of Munc18-1 rely on distinct binding modes of the central cavity with Stx1A and SNARE complex.

Shi, Lei; Kümmel, Daniel; Coleman, Jeff; Melia, Thomas J; Giraudo, Claudio G.

Mol Biol Cell ; 22(21): 4150-60, 2011 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-21900493

18.

Complexin activates and clamps SNAREpins by a common mechanism involving an intermediate energetic state.

Li, Feng; Pincet, Frédéric; Perez, Eric; Giraudo, Claudio G; Tareste, David; Rothman, James E.

Nat Struct Mol Biol ; 18(8): 941-6, 2011 Jul 24.

Artículo en Inglés | MEDLINE | ID: mdl-21785413

19.

Complexin cross-links prefusion SNAREs into a zigzag array.

Kümmel, Daniel; Krishnakumar, Shyam S; Radoff, Daniel T; Li, Feng; Giraudo, Claudio G; Pincet, Frederic; Rothman, James E; Reinisch, Karin M.

Nat Struct Mol Biol ; 18(8): 927-33, 2011 Jul 24.

Artículo en Inglés | MEDLINE | ID: mdl-21785414

20.

A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion.

Krishnakumar, Shyam S; Radoff, Daniel T; Kümmel, Daniel; Giraudo, Claudio G; Li, Feng; Khandan, Lavan; Baguley, Stephanie Wood; Coleman, Jeff; Reinisch, Karin M; Pincet, Frederic; Rothman, James E.

Nat Struct Mol Biol ; 18(8): 934-40, 2011 Jul 24.

Artículo en Inglés | MEDLINE | ID: mdl-21785412

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