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1.
Evidence of protective effects of recombinant ADAMTS13 in a humanized model of sickle cell disease.
Haematologica
; 107(11): 2650-2660, 2022 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35443560
2.
Evaluation of Factor VIII Polysialylation: Identification of a Longer-Acting Experimental Therapy in Mice and Monkeys.
J Pharmacol Exp Ther
; 371(1): 95-105, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31366602
3.
Determination of in Vivo Enzyme Occupancy Utilizing Inhibitor Dissociation Kinetics.
J Am Chem Soc
; 137(35): 11230-3, 2015 Sep 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-26301491
4.
Treatment with recombinant ADAMTS13, alleviates hypoxia/reoxygenation-induced pathologies in a mouse model of human sickle cell disease.
J Thromb Haemost
; 21(2): 269-275, 2023 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36700507
5.
Absence of exaggerated pharmacology by recombinant ADAMTS13 in the rat and monkey.
Blood Coagul Fibrinolysis
; 33(1): 56-60, 2022 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34267062
6.
Generation and selection of novel fully human monoclonal antibodies that neutralize Dickkopf-1 (DKK1) inhibitory function in vitro and increase bone mass in vivo.
J Biol Chem
; 285(51): 40135-47, 2010 Dec 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-20929859
7.
A rate-limiting role for Dickkopf-1 in bone formation and the remediation of bone loss in mouse and primate models of postmenopausal osteoporosis by an experimental therapeutic antibody.
J Pharmacol Exp Ther
; 338(2): 568-78, 2011 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21531794
8.
A regulatory circuit mediating convergence between Nurr1 transcriptional regulation and Wnt signaling.
Mol Cell Biol
; 27(21): 7486-96, 2007 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-17709391
9.
Coagulation phenotype of wild-type mice on different genetic backgrounds.
Lab Anim
; 53(1): 43-52, 2019 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-30419767
10.
Suppression of cathepsin K biomarker in synovial fluid as a free-drug-driven process.
J Circ Biomark
; 8: 1849454418821819, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30671145
11.
Pharmacokinetics, disease-modifying activity, and safety of an experimental therapeutic targeting an immunological isoform of macrophage migration inhibitory factor, in rat glomerulonephritis.
Eur J Pharmacol
; 820: 206-216, 2018 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29274331
12.
Applicability of in vitro-in vivo translation of cathepsin K inhibition from animal species to human with the use of free-drug hypothesis.
Naunyn Schmiedebergs Arch Pharmacol
; 390(4): 435-441, 2017 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-28220210
13.
Increased muscle force production and bone mineral density in ActRIIB-Fc-treated mature rodents.
J Gerontol A Biol Sci Med Sci
; 68(10): 1181-92, 2013 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-23525481
14.
Pharmacodynamic responses to combined treatment regimens with the calcium sensing receptor antagonist JTT-305/MK-5442 and alendronate in osteopenic ovariectomized rats.
Bone
; 50(6): 1332-42, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22445539
15.
Evidence for an enhancement of excitatory transmission in adult CNS by Wnt signaling pathway modulation.
Mol Cell Neurosci
; 35(4): 513-24, 2007 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-17588772
16.
Mapping of MST1 kinase sites of phosphorylation. Activation and autophosphorylation.
J Biol Chem
; 277(45): 42987-96, 2002 Nov 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-12223493
17.
The expression of matrix metalloproteinase-13 and osteocalcin in mouse osteoblasts is related to osteoblastic differentiation and is modulated by 1,25-dihydroxyvitamin D3 and thyroid hormones.
Cell Biol Int
; 27(6): 459-68, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-12798773
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