Influence of fascicle strain and corticospinal excitability during eccentric contractions on force loss.

NEW FINDINGS: What is the central question of this study? Do neural and/or mechanical factors determine the extent of muscle damage induced by eccentric contractions? What is the main finding and its importance? The extent of muscle damage induced by eccentric contractions is related to both mechanical strain and corticospinal excitability measured at long muscle lengths during eccentric contractions. ABSTRACT: In this study, we investigated whether the mechanical and neural characteristics of maximal voluntary eccentric contractions would determine the extent of change in postexercise maximal voluntary isometric contraction (MVC) torque and muscle soreness. Eleven men performed 10 sets of 15 isokinetic (45 deg s-1 ) maximal voluntary eccentric knee extensions. Knee-extension torque and vastus lateralis fascicle length were assessed at sets 1, 5 and 9. Vastus lateralis motor evoked potential, maximal M wave (MEP/M) and the cortical silent period (CSP) were measured at 75 and 100 deg of knee flexion (0 deg = full extension) during contractions and were normalized to MEP/M (MEP/Mecc/iso ) and CSP (CSPecc/iso ) recorded during isometric MVC at each angle. The MVC torque and muscle soreness of the knee extensors were assessed before, 24, 48 and 96 h after the eccentric contractions. The extent of relative decrease in MVC torque at 24 h postexercise (r2  = 0.38) and peak muscle soreness (r2  = 0.69) were correlated (P < 0.05) with MEP/Mecc/iso measured at 100 deg, but not at 75 deg. The average torque on the descending limb of the torque-angle relationship (r2  = 0.16), fascicle elongation (r2  = 0.18) and CSPecc/iso at both 75 (r2  = 0.00) and 100 deg (r2  = 0.02) were not significantly correlated with the relative decrease in MVC torque. The relative decrease in MVC torque was best predicted by a combination of mean torque on the descending limb, fascicle elongation and MEP/Mecc/iso (R2  = 0.93). It is concluded that the extent of muscle damage based on the reduction in MVC torque is determined by mechanical strain and corticospinal excitability at long muscle lengths during maximal voluntary eccentric contractions.

Muscle length effect on corticospinal excitability during maximal concentric, isometric and eccentric contractions of the knee extensors.

NEW FINDINGS: What is the central question of this study? Does sensory input from peripheral mechanoreceptors determine the specific neural control of eccentric contractions? How corticospinal excitability (i.e. muscle responses to motor cortex stimulation) is affected by muscle length has never been investigated during eccentric contractions. What is the main finding and its importance? Muscle length does not influence corticospinal excitability during concentric and isometric maximal contractions, but does during eccentric maximal contractions. This indicates that neural control in eccentric contractions differs from that in concentric and isometric contractions. Neural control of eccentric contractions differs from that of concentric and isometric contractions, but no previous study has compared responses to motor cortex stimulations at long muscle lengths during such contraction types. In this study, we compared the effect of muscle length on corticospinal excitability between maximal concentric, isometric and eccentric contractions of the knee extensors. Twelve men performed 12 maximal concentric, isometric and eccentric voluntary contractions (36 contractions in total), separated by a 5 min rest between contraction types. The 12 contractions for the same contraction type were performed every 10 s, and transcranial magnetic stimulations (first eight contractions) and electrical femoral nerve stimulations (last four contractions) were superimposed alternately at 75 and 100 deg of knee flexion. Average motor evoked potential amplitude, normalized to the maximal M wave amplitude (MEP/M) and cortical silent period duration were calculated for each angle and compared among the contraction types. The MEP/M was lower (-23 and -28%, respectively) during eccentric than both concentric and isometric contractions at 75 deg, but similar between contraction types at 100 deg (P < 0.05). The cortical silent period duration was shorter (-12 and -10%, respectively) during eccentric than both concentric and isometric contractions at 75 deg, but longer (+11 and +9%, respectively) during eccentric contractions at 100 deg (P < 0.05). These results show that corticospinal excitability during eccentric contractions is angle dependent such that cortical inhibitory processes are greater with no alteration of corticospinal excitability at 100 deg, whereas this control is reversed at 75 deg.

Specific joint angle dependency of voluntary activation during eccentric knee extensions.

INTRODUCTION: This study compared voluntary activation during isometric, concentric, and eccentric maximal knee extensions at different joint angles. METHODS: Fifteen participants performed isometric, concentric, and eccentric protocols (9 contractions each). For each protocol, the central activation ratio (CAR) was randomly measured at 50°, 75°, or 100° of knee joint angle (0° = full knee extension) using superimposed supramaximal paired nerve stimulations during contractions. RESULTS: CAR increased between 50° and 100° during isometric (93.6 ± 3.1 vs. 98.5 ± 1.4%), concentric (92.4 ± 5.4 vs. 99.2 ± 1.2%), and eccentric (93.0 ± 3.5 vs. 96.6 ± 3.8%) contractions. CAR was lower during eccentric than both isometric and concentric contractions at 75° and 100°, but similar between contraction types at 50°. CONCLUSIONS: The ability to activate muscle maximally is impaired during eccentric contractions compared with other contraction types at 75° and 100°, but not at 50°. Muscle Nerve 56: 750-758, 2017.

Motor adaptations to local muscle pain during a bilateral cyclic task.

The aim of this study was to determine how unilateral pain, induced in two knee extensor muscles, affects muscle coordination during a bilateral pedaling task. Fifteen participants performed a 4-min pedaling task at 130 W in two conditions (Baseline and Pain). Pain was induced by injection of hypertonic saline into the vastus medialis (VM) and vastus lateralis (VL) muscles of one leg. Force applied throughout the pedaling cycle was measured using an instrumented pedal and used to calculate pedal power. Surface electromyography (EMG) was recorded bilaterally from eight muscles to assess changes in muscle activation strategies. Compared to Baseline, during the Pain condition, EMG amplitude of muscles of the painful leg (VL and VM-the painful muscles, and RF-another quadriceps muscle with no pain) was lower during the extension phase [(mean ± SD): VL: -22.5 ± 18.9%; P < 0.001; VM: -28.8 ± 19.9%; P < 0.001, RF: -20.2 ± 13.9%; P < 0.001]. Consistent with this, pedal power applied by the painful leg was also lower during the extension phase (-16.8 ± 14.2 W, P = 0.001) during Pain compared to Baseline. This decrease was compensated for by an 11.3 ± 8.1 W increase in pedal power applied by the non-painful leg during its extension phase (P = 0.04). These results support pain adaptation theories, which suggest that when there is a clear opportunity to compensate, motor adaptations to pain occur to decrease load within the painful tissue. Although the pedaling task offered numerous possibilities for compensation, only between-leg compensations were systematically observed. This finding is discussed in relation to the mechanical and neural constraints of the pedaling task.

Non-invasive assessment of muscle stiffness in patients with Duchenne muscular dystrophy.

INTRODUCTION: Assessment of muscle mechanical properties may provide clinically valuable information for follow-up of patients with Duchenne muscular dystrophy (DMD) through the course of their disease. In this study we aimed to assess the effect of DMD on stiffness of relaxed muscles using elastography (supersonic shear imaging). METHODS: Fourteen DMD patients and 13 control subjects were studied. Six muscles were measured at 2 muscle lengths (shortened and stretched): gastrocnemius medialis (GM); tibialis anterior (TA); vastus lateralis (VL); biceps brachii (BB); triceps brachii (TB); and abductor digiti minimi (ADM). RESULTS: Stiffness was significantly higher in DMD patients compared with controls for all the muscles (main effect for population, P < 0.033 in all cases), except for ADM. The effect size was small (d = 0.33 for ADM at both muscle lengths) to large (d = 0.86 for BB/stretched). CONCLUSIONS: Supersonic shear imaging is a sensitive non-invasive technique to assess the increase in muscle stiffness associated with DMD.

Impact of forearm fatigue on the postural response to an externally initiated, predictable perturbation.

PURPOSE: The objective was to examine the impact of non-postural muscle fatigue on anticipatory postural control, during postural perturbations induced by platform translations. The experimental setup investigated the central changes caused by fatigue without the potential confounding influence of peripheral fatigue within the postural muscles. METHODS: Fatigue induced in forearm muscles by a maximal handgrip contraction has been previously shown to influence forearm force production for 10 min, reduce ankle plantarflexion force for 1 min and create measureable central fatigue for 30 s. The peak-to-peak anterior/posterior displacement of the center of mass and center of pressure (COP) and muscle activity were measured during the postural perturbation tasks performed before the fatigue protocol and for 10 min post-fatigue. RESULTS: The fatigue protocol decreased the peak-to-peak COP displacement from 128.0 ± 12.3 mm pre-fatigue to 81.9 ± 7.8 mm post-fatigue during the forwards platform translation (p < 0.05) and from 133.8 ± 12.0 to 89.2 ± 7.9 mm during the backwards translation (p < 0.05). The fatigue protocol also caused the tibialis anterior (TA pre-fatigue = -0.25 ± 0.04 s, TA post-fatigue = -0.41 ± 0.02 s, p = 0.001) and medial gastrocnemius muscles (MG pre-fatigue = -0.39 ± 0.03 s, MG post-fatigue = -0.48 ± 0.02 s, p = 0.028) to be recruited significantly earlier relative to the pre-fatigue condition. CONCLUSION: This experimental setup ensured that peripheral fatigue did not develop in the postural muscles; therefore, a general fatigued-induced modification of the postural strategy is proposed as the origin of the postural changes and delayed recovery.

Fatiguing handgrip exercise alters maximal force-generating capacity of plantar-flexors.

Exercise-induced fatigue causes changes within the central nervous system that decrease force production capacity in fatigued muscles. The impact on unrelated, non-exercised muscle performance is still unclear. The primary aim of this study was to examine the impact of a bilateral forearm muscle contraction on the motor function of the distal and unrelated ankle plantar-flexor muscles. The secondary aim was to compare the impact of maximal and submaximal forearm contractions on the non-fatigued ankle plantar-flexor muscles. Maximal voluntary contractions (MVC) of the forearm and ankle plantar-flexor muscles as well as voluntary activation (VA) and twitch torque of the ankle plantar-flexor muscles were assessed pre-fatigue and throughout a 10-min recovery period. Maximal (100 % MVC) and submaximal (30 % MVC) sustained isometric handgrip contractions caused a decreased handgrip MVC (to 49.3 ± 15.4 and 45.4 ± 11.4 % of the initial MVC for maximal and submaximal contraction, respectively) that remained throughout the 10-min recovery period. The fatigue protocols also caused a decreased ankle plantar-flexor MVC (to 77 ± 8.3 and 92.4 ± 6.2 % of pre-fatigue MVC for maximal and submaximal contraction, respectively) and VA (to 84.3 ± 15.7 and 97.7 ± 16.1 % of pre-fatigue VA for maximal and submaximal contraction, respectively). These results suggest central fatigue created by the fatiguing handgrip contraction translated to the performance of the non-exercised ankle muscles. Our results also show that the maximal fatigue protocol affected ankle plantar-flexor MVC and VA more severely than the submaximal protocol, highlighting the task-specificity of neuromuscular fatigue.

Prediction of time-to-exhaustion in the first dorsal interosseous muscle from early changes in surface electromyography parameters.

INTRODUCTION: In this study we evaluated the precision of the time-to-exhaustion (T(lim)) prediction from the early changes in surface electromyography (sEMG) of the first dorsal interosseous muscle. METHODS: Thirty subjects performed an index finger isometric abduction at 35% of maximal voluntary contraction (MVC) until exhaustion. Ten participants performed the same exercise at 50% MVC 1 week later. Changes in sEMG parameters across time were modeled using the area-ratio and the linear regression slope. T(lim) was plotted as a function of each of these indices of change, and the coefficient of determination (R(2)) was determined. RESULTS: Null to moderate R(2) (0.22 and 0.56 at 35% and 50% MVC, respectively) values were calculated. The best T(lim) estimation led to a high prediction error (21.6 ± 15.0% of T(lim) for the 50% MVC task). CONCLUSIONS: Although the prediction of time-to-exhaustion is an appealing research topic, these results suggest that it cannot be done solely from sEMG.

Impact of ankle muscle fatigue and recovery on the anticipatory postural adjustments to externally initiated perturbations in dynamic postural control.

The aim of this study was to determine whether and how young participants modulate their postural response to compensate for postural muscle fatigue during predictable but externally initiated continuous and oscillatory perturbations. Twelve participants performed ten postural trials before and after an ankle muscle fatigue protocol. Each postural trial was 1 min long and consisted of continuous backward and forward oscillations of the platform. Fatigue was induced by intermittent, bilateral isometric contractions of the ankle plantar- and dorsiflexors until the force production was reduced to 50 % of the pre-fatigue maximal voluntary contraction. Changes in the center of mass (COM) displacement, center of pressure (COP) displacement, and anterior-posterior location of the COP within the base of support were quantified as well as the activity of the tibialis anterior (TA), medial gastrocnemius (MG), quadriceps, and hamstring. All participants demonstrated postural stability post-fatigue by maintaining the displacement of their COM. Everyone also demonstrated a general forward shift in the anterior-posterior location of the COP within the base of support; however, two distinct postural modifications, corresponding to either an immediate fatigue-induced increase or decrease in the COP displacement during the backward platform translation, were recorded immediately post-fatigue. The changes in muscle onset latencies lasted beyond the recovery of the force production of the fatigued postural muscles. By 10 min post-fatigue, the participants showed a decrease in the COP displacement as well as an earlier activation of the postural muscles and an increased TA/MG co-activation relative to pre-fatigue. Although different strategies were used, the participants were able to adjust to and overcome postural muscle fatigue and remain balanced during the postural perturbations regardless of the direction of the platform movement. These adjustments lasted beyond the recovery of the ankle muscle force production indicating that they may be part of a centrally mediated protective response as opposed to a peripherally induced limitation to performance.

Fatigue-related adaptations in muscle coordination during a cyclic exercise in humans.

Muscle fatigue is an exercise-induced reduction in the capability of a muscle to generate force. A possible strategy to counteract the effects of fatigue is to modify muscle coordination. We designed this study to quantify the effect of fatigue on muscle coordination during a cyclic exercise involving numerous muscles. Nine human subjects were tested during a constant-load rowing exercise (mean power output: 217.9±32.4 W) performed until task failure. The forces exerted at the handle and the foot-stretcher were measured continuously and were synchronized with surface electromyographic (EMG) signals measured in 23 muscles. In addition to a classical analysis of individual EMG data (EMG profile and EMG activity level), a non-negative matrix factorization algorithm was used to identify the muscle synergies at the start and the end of the test. Among the 23 muscles tested, 16 showed no change in their mean activity level across the rowing cycle, five (biceps femoris, gluteus maximus, semitendinosus, trapezius medius and vastus medialis) showed a significant increase and two (gastrocnemius lateralis and longissimus) showed a significant decrease. We found no change in the number of synergies during the fatiguing test, i.e. three synergies accounted for more than 90% of variance accounted for at the start (92.4±1.5%) and at the end (91.0±1.8%) of the exercise. Very slight modifications at the level of individual EMG profiles, synergy activation coefficients and muscle synergy vectors were observed. These results suggest that fatigue during a cyclic task preferentially induces an adaptation in muscle activity level rather than changes in the modular organization of the muscle coordination.

Influence of exercise intensity and joint angle on endurance time prediction of sustained submaximal isometric knee extensions.

The purpose of endurance time (T (lim)) prediction is to determine the exertion time of a muscle contraction before it occurs. T (lim) prediction would then allow the evaluation of muscle capacities limiting fatigue and deleterious effects associated with exhaustive exercises. The present study aimed to analyze the influence of exercise intensity and joint angle on T (lim) prediction using changes in surface electromyographic (sEMG) signals recorded during the first moments of the exercise. Fifteen male performed four knee extensions sustained until exhaustion that were different in exercise intensity (20% or 50% of maximal voluntary torque-MVT) and in joint angle (40 or 70º, 0° = full extension). T (lim) prediction was explored using some parameters of the sEMG signals from rectus femoris, vastus medialis and vastus lateralis muscles. Changes in sEMG parameters (root mean square, mean power frequency and frequency banding 6-30 Hz) were expressed using the slope of the linear regression and the area ratio index. Results indicated that relationships between changes in sEMG signal and T (lim) (0.51 < r < 0.83) were greater for experimental conditions associated with higher exercise intensity (50% MVT) and so to lower time duration. Knee joint angle had little influence on T (lim) prediction results. Results also showed higher T (lim) prediction considering spectral parameters and area ratio. This could be in relation to differences in relative contribution of central and peripheral fatigue that seems to change according to the exercise intensity, but also to the influence of psychological factors that increases with the duration of the task.

Muscle architecture and EMG activity changes during isotonic and isokinetic eccentric exercises.

The present study aimed to compare muscle architecture and electromyographic activity during isotonic (IT) and isokinetic (IK) knee extensors eccentric contractions. Seventeen subjects were assigned in test and reproducibility groups. During test session, subjects performed two IT and two IK sets of eccentric contractions of knee extensor muscles. Torque, angular velocity, VL architecture and EMG activity of agonist (vastus lateralis, VL; vastus medialis; rectus femoris) and antagonist (semitendinosus; biceps femoris, BF) muscles were simultaneously recorded and averaged on a 5° window. Torque-angle and angular velocity-angle relationships exhibited differences in mechanical load between the IT and IK modes. Changes in muscle architecture were similar in both modes, since VL fascicles length increased and fascicle angle decreased, resulting in a decrease in muscle thickness during eccentric contraction. Agonist activity and BF co-activity levels were higher in IT mode than in IK mode at short muscle lengths, whereas agonist activity was higher in IK mode than in IT mode at long muscle lengths. Differences in mechanical load between both modes induced specific neuromuscular responses in terms of agonist activity and antagonist co-activity. These results suggest that specific neural adaptations may occur after IT or IK eccentric training. This hypothesis needs to be tested in order to gain new insights concerning the most effective eccentric protocols based on whether the objective is sportive or clinical.

Effect of power output on muscle coordination during rowing.

The present study was designed to quantify the effect of power output on muscle coordination during rowing. Surface electromyographic (EMG) activity of 23 muscles and mechanical variables were recorded in eight untrained subjects and seven experienced rowers. Each subject was asked to perform three 2-min constant-load exercises performed at 60, 90 and 120% of the mean power output over a maximal 2,000-m event (denoted as P60, P90, and P120, respectively). A decomposition algorithm (nonnegative matrix factorization) was used to extract the muscle synergies that represent the global temporal and spatial organization of the motor output. The results showed a main effect of power output for 22 of 23 muscles (p values ranged from <0.0001 to 0.004) indicating a significant increase in EMG activity level with power output for both untrained and experienced subjects. However, for the two populations, no dramatic modification in the shape of individual EMG patterns (mean r (max) value = 0.93 ± 0.09) or in their timing of activation (maximum lag time = -4.3 ± 3.8% of the rowing cycle) was found. The results also showed a large consistency of the three extracted muscle synergies, for both synergy activation coefficients (mean r (max) values range from 0.87 to 0.97) and muscle synergy vectors (mean r values range from 0.70 to 0.76) across the three power outputs. In conclusion, despite significant changes in the level of muscle activity, the global temporal and spatial organization of the motor output is very little affected by power output on a rowing ergometer.

Neuromuscular adaptations to 8-week strength training: isotonic versus isokinetic mode.

Previous studies attempted to compare the effectiveness of isokinetic and isotonic training. However, they have provided conflicting results. The purpose of this study was to compare the effects of isotonic versus isokinetic standardized concentric strength training programs of the knee extensors on the neuromuscular system. The standardization of these two training programs was ensured by the equalization of the total external amount of work performed and the mean angular movement velocity. Thirty healthy male students were randomly assigned to the isotonic (IT; n = 11), the isokinetic (IK; n = 11) or the control (C; n = 8) group. Both IT and IK groups trained their dominant lower leg 3 sessions/week for 8 weeks on a dynamometer. The IT group exercised using a preset torque of 40% of the maximal voluntary isometric torque at 70 degrees (0 degrees = leg in horizontal position). The IK group exercised at a velocity ranging between 150 degrees and 180 degrees s(-1). Isotonic, isokinetic and isometric tests were performed on a dynamometer before and after strength training. Surface electromyographic activity of vastus lateralis, vastus medialis, rectus femoris, semitendinosus and biceps femoris muscles was recorded during the tests. Significant strength increases in both dynamic and static conditions were noticed for IT and IK groups without any significant difference between the two trained groups. Agonist muscle activity also increased with training but no change in antagonist muscle co-activity was observed. The two training methods could be proposed by clinicians and athletic coaches to improve concentric muscle strength in dynamic and static conditions.

A new device to study isoload eccentric exercise.

This study was designed to develop a new device allowing mechanical analysis of eccentric exercise against a constant load, with a view in mind to compare isoload (IL) and isokinetic (IK) eccentric exercises. A plate-loaded resistance training device was integrated to an IK dynamometer, to perform the acquisition of mechanical parameters (i.e., external torque, angular velocity). To determine the muscular torque produced by the subject, load torque was experimentally measured (TLexp) at 11 different loads from 30° to 90° angle (0° = lever arm in horizontal position). TLexp was modeled to take friction effect and torque variations into account. Validity of modeled load torque (TLmod) was tested by determining the root mean square (RMS) error, bias, and 2SD between the descending part of TLexp (from 30° to 90°) and TLmod. Validity of TLexp was tested by a linear regression and a Passing-Bablok regression. A pilot analysis on 10 subjects was performed to determine the contribution of the torque because of the moment of inertia to the amount of external work (W). Results showed the validity of TLmod (bias = 0%; RMS error = 0.51%) and TLexp SEM = 4.1 N·m; Intraclass correlation coefficient (ICC) = 1.00; slope = 0.99; y-intercept = -0.13). External work calculation showed a satisfactory reproducibility (SEM = 38.3 J; ICC = 0.98) and moment of inertia contribution to W showed a low value (3.2 ± 2.0%). Results allow us to validate the new device developed in this study. Such a device could be used in future work to study IL eccentric exercise and to compare the effect of IL and IK eccentric exercises in standardized conditions.

Electromechanical delay revisited using very high frame rate ultrasound.

Electromechanical delay (EMD) represents the time lag between muscle activation and muscle force production and is used to assess muscle function in healthy and pathological subjects. There is no experimental methodology to quantify the actual contribution of each series elastic component structures that together contribute to the EMD. We designed the present study to determine, using very high frame rate ultrasound (4 kHz), the onset of muscle fascicles and tendon motion induced by electrical stimulation. Nine subjects underwent two bouts composed of five electrically evoked contractions with the echographic probe maintained over 1) the gastrocnemius medialis muscle belly (muscle trials) and 2) the myotendinous junction of the gastrocnemius medialis muscle (tendon trials). EMD was 11.63 +/- 1.51 and 11.67 +/- 1.27 ms for muscle trials and tendon trials, respectively. Significant difference (P < 0.001) was found between the onset of muscle fascicles motion (6.05 +/- 0.64 ms) and the onset of myotendinous junction motion (8.42 +/- 1.63 ms). The noninvasive methodology used in the present study enabled us to determine the relative contribution of the passive part of the series elastic component (47.5 +/- 6.0% of EMD) and each of the two main structures of this component (aponeurosis and tendon, representing 20.3 +/- 10.7% and 27.6 +/- 11.4% of EMD, respectively). The relative contributions of the synaptic transmission, the excitation-contraction coupling, and the active part of the series elastic component could not be directly quantified with our results. However, they suggest a minor role of the active part of the series elastic component that needs to be confirmed by further experiments.

Can the electromyographic fatigue threshold be determined from superficial elbow flexor muscles during an isometric single-joint task?

The purpose of this study was to compare the electromyographic fatigue threshold (EMG(FT)) values determined simultaneously from superficial elbow flexor muscles during an isometric single-joint task. Eight subjects performed isometric elbow flexions at randomly ordered percentages of maximal voluntary contraction (20, 30, 40, 50 and 60%). During these bouts, electromyographic (EMG) activity was measured in the anterior head of Deltoïd, lateral head of Triceps brachii, Brachioradialis and both short and long head of Biceps brachii. For each subject and each muscle, the EMG amplitude data were plotted as function of time for the five submaximal bouts. The slope coefficient of the EMG amplitude versus time linear relationships were plotted against force level. EMG(FT) was determined as the y-intercept of this relationship and considered as valid only if the following criteria were met: (1) significant positive linear regression (P < 0.05) between force and slope coefficient, (2) an adjusted coefficient of determination for force versus slope coefficient relationship greater than 0.85, and (3) a standard error for the EMG(FT) below 5% of maximal voluntary contraction. The EMG(FT) could only be determined for one muscle (the long head of Biceps brachii) and only in three out of the eight subjects (mean value = 24.9 +/- 1.1% of maximal voluntary contraction). The lack of EMG(FT) in most of the subjects (5/8) could be explained by putative compensations between elbow muscles which were indirectly observed in some subjects. In this way, EMG(FT) should be studied from a more simple movement i.e., ideally a movement implying mainly one muscle.

Comparison of two methodological approaches for the mechanical analysis of single-joint isoinertial movement using a customised isokinetic dynamometer.

Compared to isokinetic and isometric tests, isoinertial movements have been poorly used to assess single-joint performance. Two calculation procedures were developed to estimate mechanical performance during single-joint isoinertial movements performed on a customised isokinetic dynamometer. The results were also compared to appreciate the effects of measurement systems and calculation procedures. Five participants performed maximal knee extensions at four levels of resistance (30, 50, 70 and 90% of the one-repetition maximum, 1-RM). Joint angular velocity and torque were assessed from customised isokinetic dynamometer measures (method A) and from weight stack kinematic (method B). Bland-Altman plots and mean percent differences (Mdiff) were used to assess the level of agreement for mean and peak angular velocity and torque. A Passing-Bablok regression was performed to compare the angular velocity-angle and torque-angle relationships computed from the two analysis methods. The results showed a high level of agreement for all mechanical parameters (Mdiff < 6% for all parameters). No statistically significant differences were observed between methods A and B in terms of angular velocity-angle and torque-angle relationships except at 30% of 1-RM for the torque-angle relationship. Both methodologies provide comparable values of angular velocity and torque, offering alternative approaches to assess neuromuscular function from single-joint isoinertial movements.

Changes in Motor Coordination Induced by Local Fatigue during a Sprint Cycling Task.

PURPOSE: This study investigated how muscle coordination is adjusted in response to a decrease in the force-generating capacity of one muscle group during a sprint cycling task. METHODS: Fifteen participants were tested during a sprint before and after a fatigue electromyostimulation protocol was conducted on the quadriceps of one leg. Motor coordination was assessed by measuring myoelectrical activity, pedal force, and joint power. RESULTS: The decrease in force-generating capacity of the quadriceps (-28.0% ± 6.8%) resulted in a decrease in positive knee extension power during the pedaling task (-34.4 ± 30.6 W; P = 0.001). The activity of the main nonfatigued synergist and antagonist muscles (triceps surae, gluteus maximus and hamstrings) of the ipsilateral leg decreased, leading to a decrease in joint power at the hip (-30.1 ± 37.8 W; P = 0.008) and ankle (-20.8 ± 18.7 W; P = 0.001). However, both the net power around the knee and the ability to effectively orientate the pedal force were maintained during the extension by reducing the coactivation and the associated negative power produced by the hamstrings. Adaptations also occurred in flexion phases in both legs, exhibiting an increased power (+17.9 ± 28.3 [P = 0.004] and +19.5 ± 21.9 W [P = 0.026]), associated with an improvement in mechanical effectiveness. CONCLUSION: These results demonstrate that the nervous system readily adapts coordination in response to peripheral fatigue by (i) decreasing the activation of adjacent nonfatigued muscles to maintain an effective pedal force orientation (despite reducing pedal power) and (ii) increasing the neural drive to muscles involved in the flexion phases such that the decrease in total pedal power is limited.