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For the development of photonic integrated circuits and lithium niobate (L i N b O 3, LN) optical waveguide technology, the implementation and application of polarization devices based on LN are also becoming more widespread, where titanium (Ti)-diffused LN waveguides form the basis of many important electro-optic (EO) integrated optical devices. Moreover, utilizing polarization conversion has the potential to enhance both the effectiveness and capacity of optical transmission. Thus, we have presented an EO polarization mode converter packaging with PANDA polarization-maintaining optical fibers (PMFs) in the broadband wavelength range (1440-1620 nm) to obtain the multiwavelength modulation, featuring the wavelength tunability. Additionally, the fabricated device is able to achieve transverse electric (TE) to transverse magnetic (TM) mode conversion efficiently with the applied voltage of ±, which provides high conversion efficiency. Importantly, our device also features a high-frequency response of about 600 MHz with overall insertion loss below 5 dB. The rapid development of LN-based polarization devices holds great promise for chip-integrated systems in the field of polarization telecommunication.
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Aristolochic acid (AA) as an emerging contaminant in herbal medicines or crops has been well-recognized for causing nephropathy since 1990s. Over the last decade, mounting evidence has linked AA to liver injury; however, the underlying mechanism is poorly elucidated. MicroRNAs respond to environmental stress and mediate multiple biological processes, thus showing biomarker potentials prognostically or diagnostically. In the present study, we investigated the role of miRNAs in AA-induced hepatotoxicity, specifically in regulating NQO1, the key enzyme responsible for AA bioactivation. In silico analysis showed that hsa-miR-766-3p and hsa-miR-671-5p were significantly associated with AAI exposure as well as NQO1 induction. A 28-day rat experiment of 20 mg/kg AA exposure demonstrated a 3-fold increase of NQO1 and an almost 50 % decrease of the homologous miR-671 that were accompanied with liver injury, which was consistent with in silico prediction. Further mechanistic investigation using Huh7 cells with IC50 of AAI at 146.5 µM showed both hsa-miR-766-3p and hsa-miR-671-5p were able to directly bind to and down-regulate NQO1 basal expression. In addition, both miRNAs were shown to suppress AAI-induced NQO1 upregulation in Huh7 cells at a cytotoxic concentration of 70 µM, and consequently alleviate AAI-induced cellular effects, including cytotoxicity and oxidative stress. Together, these data illustrate that miR-766-3p and miR-671-5p attenuate AAI-induced hepatotoxicity, and thus have monitoring and diagnostic potentials.
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Ácidos Aristolóquicos , Enfermedad Hepática Inducida por Sustancias y Drogas , MicroARNs , NAD(P)H Deshidrogenasa (Quinona) , Animales , Ratas , Ácidos Aristolóquicos/toxicidad , Enfermedad Hepática Inducida por Sustancias y Drogas/genética , MicroARNs/genética , NAD(P)H Deshidrogenasa (Quinona)/genética , NAD(P)H Deshidrogenasa (Quinona)/metabolismo , HumanosRESUMEN
We propose an electro-optic on-chip beam shifting device based on gradient microstructured electrodes and an optical tapered waveguide fabricated using lithium niobate (LN). The distribution of refractive index variations of the optical waveguide can be electro-optically defined and tailored by the designed gradient microstructured electrodes, which directs the beam propagation and shifting. The length of the beam shifting device is 18 mm and the width of the waveguide is gradually increased from 8 µm to 80 µm. The functionality of the beam shifting device is experimentally demonstrated, and it is observed that it has an electro-optic tunability of 0.41 µm/V, and a high-speed response time of 19 ns (λ=1310 nm). This study can provide potential applications in optical switching and modulation, beam scanning and ranging, optical spatial communications, etc.
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This paper presents an ultrasensitive temperature sensor and tunable mode converter based on an isopropanol-sealed modal interferometer in a two-mode fiber. The modal interferometer consists of a tapered two-mode fiber (TTMF) sandwiched between two single-mode fibers. The sensor provides high-sensitivity temperature sensing by taking advantages of TTMF, isopropanol and the Vernier-like effect. The TTMF provides a uniform modal interferometer with LP01 and LP11 modes as well as strong evanescent field on its surface. The temperature sensitivity of the sensor can be improved due to the high thermo-optic coefficient of isopropanol. The Vernier-like effect based on the overlap of two interference spectra is applied to magnify the sensing capabilities with a sensitivity magnification factor of 58.5. The temperature sensor is implemented by inserting the modal interferometer into an isopropanol-sealed capillary. The experimental and calculated results show the transmission spectrum exhibit blue shift with increasing ambient temperature. Experimental results show that the isopropanol-sealed modal interferometer provides a temperature sensitivity up to -140.5â nm/°C. The interference spectrum has multiple dips at which the input LP01 mode is converted to the LP11 mode. This modal interferometer acts as a tunable multi-channel mode converter. The mode converter that can be tuned by varying temperature and mode switch is realized.
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We propose the broadband mode-selective coupler (MSC) formed with a side-polished six mode fiber (6MF) and a tapered side-polished small core single-mode fiber (SC-SMF) or an SMF. The MSCs are designed to allow the LP01 mode in the SC-SMF and SMF to completely couple to the LP01, LP11, LP21, LP02, LP31, LP12 modes in the 6MF over a broadband wavelength range. The phase-matching conditions of the MSCs are satisfied by tapering the SC-SMF and SMF to specific diameters. The tapered fibers are side-polished to designed residual fiber thickness using the wheel polishing technique. The effective indices of the side-polished fibers are measured with the prism coupling method. The MSCs provide high coupling ratio and high mode purity. High coupling efficiencies in excess of 81% for all the higher-order modes are obtained in the wavelength range 1530-1600â nm. For the LP01, LP11, LP21, LP02, LP31, LP12 MSCs at 1550â nm, the coupling ratios are 96.2%, 99.8%, 89.5%, 85.0%, 90.9%, 96.1%, respectively, and the mode purity of the MSCs is higher than 88.0%. The loss of the MSCs is lower than 1.8â dB in the wavelength range 1530-1600â nm. This device can be applied in broadband mode-division multiplexing transmission systems.
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Bound states in the continuum (BICs) are ubiquitous physical phenomena where such states occur due to strong coupling between leaky modes in side lossy systems. BICs in meta-optics and nanophotonics enable optical mode confinement to strengthen local field enhancement in nonlinear optics. In this study, we numerically investigate second-harmonic generation (SHG) in the vicinity of BICs with a photonic structure comprising one-dimensional nanogratings and a slab waveguide made of lithium niobate (LiNbO3, LN). By breaking the symmetry of LN nanogratings, BICs transition to quasi-BICs, which enable strong local field confinement inside LN slab waveguide to be supported, thereby resulting in improving SHG conversion with lower pump power of fundamental frequency (FW). With a peak intensity of 1.33 GW cm-2at the FW, our structure features a second-harmonic conversion efficiency up to 8.13 × 10-5at quasi-BICs. We believe that our results will facilitate the application of LN in integrated nonlinear nanophotonic.
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Polarization-sensitive Tamm plasmons are investigated in a multi-layer photonic configuration where a monolayer black phosphorus (BP) is coated on a Bragg mirror separated by a dielectric. Owing to the in-plane anisotropy of BP, the Tamm plasmon can be excited selectively by tuning the BP carrier density. Cross-polarization conversion occurs when the armchair direction of BP makes an angle with the incident plan, i.e., Ï≠0 or 90°. The BP-based Tamm device can be used as an intensity modulator with a modulation depth up to â¼100% and an insertion loss smaller than -0.55 dB. By analyzing the polarization evolution carefully, a multichannel polarization division multiplexing scheme is proposed and discussed. These findings open a new avenue for exploiting versatile tunable THz devices based on the monolayer of BP.
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An all-fiber humidity sensor is proposed and fabricated by depositing three-dimensional graphene network (3DGN) around the surface of a freestanding microfiber (MF). The high specific surface area and porosity of 3DGN enhances its interaction with water molecules, allowing high performance of the humidity sensor. The sensor can operate in a wide relative humidity (RH) range of 11.6%RH-90.9%RH with a high sensitivity of -2.841 dB/%RH in the RH range (80.3%RH - 90.9%RH). The response and recovery times of this type of microfiber sensor are measured respectively to be 57 ms and 55 ms, which are one order magnitude faster than those of other fiber RH sensors activated by two-dimensional materials coating. Such an all-fiber RH sensor with high sensitivity and fast response property possesses great potential of application in widespread fields, such as biology, chemical processing and food processing.
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A core-removed D-shaped structure with different residual thickness (RT) was manufactured on a single mode silica fiber (SMF) to enhance the sensitivity by using of ultra-precise polishing technology. With six different RTs ranging from â¼55 µm to â¼28 µm, the RT enhancement effect in a D-shaped SMF was researched in detail. The influence of the RT on its transmission spectra was investigated both theoretically and experimentally. Considering a compromise between the multimode interference efficiency and optical power loss, an optimum RT value of 34.09 µm was achieved. The obtained refractive index (RI) sensitivity was 10243 nm/RIU in the RI range of 1.430-1.444, corresponding to a RI resolution of 1.9×10-6 RIU. A high-performance all-fiber sensor was developed to monitor the evaporation process volatile organic compounds (VOCs) based on the RT-enhanced D-shaped SMF. As proof of concept, a 2-hour continuous monitoring was carried to monitor the chloroform and alcohol mixture. As a result, the evaporation of alcohol and chloroform were clearly identified and monitored. The developed RT-enhanced D-shaped fiber sensor provides an alternative way for chemical process monitoring and industrial applications.
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Surface plasmon resonance (SPR) enables strong field confinement, opening thereby new avenues for device miniaturization and reducing energy consumption. Plasmonic devices with electrical tunability attract tremendous interest for various applications. Most of the current researches achieved SPR modulation with relatively large driving voltages, or by other relatively low-speed tuning approaches, such as thermo-optic, magneto-optic, acousto-optic etc. In this paper, we propose and demonstrate an efficiently electrical SPR modulation based on lithium niobate (LN) with gold nanolayer (~81 nm) via electron-plasmon interaction. Efficient intensity modulation and wavelength shift (in visible band) of ~5.7 dB/V and ~36.3 nm/V are respectively obtained with low DC current. More importantly, modulation phenomenon of field distribution dependent is also observed and experimentally unveiled. Further performance is analyzed in terms of AC modulation and polarization characteristics. This key achievement opens up opportunities for applications such as optical interconnection, electric field sensing, electrically plasmonic modulation, etc.
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In-plane photonic spin splitting effect is investigated in tunneling terahertz waves through an epsilon-near-zero metamaterial sandwiched between monolayer black phosphorus (BP). The strong in-plane anisotropy of BP layers will induce in-plane asymmetric spin splitting. The asymmetric spin splitting can be flexibly tuned by the angles between the incident plane and the armchair crystalline directions of the top and bottom BP layers, i.e., Ï1 and Ï2. Based on this, an angle-resolved barcode-encryption scheme is discussed. For the special case of Ï1 = Ï2 = 0 or 90°, the transmitted beam undergoes Goos-Hänchen shift, which varies with the carrier density of BP. We believe these findings can facilitate the development of novel optoelectronic devices in the Terahertz region.
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The fiber geometry, fiber parameters and mode-guiding properties are crucial for realizing high-performance fiber-based sensors. In this work, we propose and demonstrate a few-mode fiber (FMF)-based surface plasmon resonance (SPR) biosensor. The FMF-SPR sensor was fabricated via side-polishing a few-mode fiber and coating a thin layer of gold film, on the basis of the optimization of fiber geometry, thickness of the gold film and mode selection, which were performed with the finite element method. The refractive index (RI) sensing performance of three such sensors with different residual fiber thicknesses were investigated. In the RI range from 1.333 to 1.404, the highest sensitivity up to 4903 nm/RIU and a figure of merit of 46.1 RIU-1 are achieved. For testing the bovine serum albumin (BSA) solution, an averaged BSA RI sensitivity of 6328 nm/RIU and an averaged BSA concentration sensitivity of 1.17 nm/(mg/ml) are realized. Benefiting from only a few modes supported in the FMF, a smaller line-width of the SPR spectrum is obtained, which further results in a higher figure of merit (FOM). Moreover, when combined with the superiority of the mode-multiplexing technology brought by the FMF, the FMF-SPR sensors may find applications in biochemical analysis with high performance and high throughputs.
Asunto(s)
Técnicas Biosensibles/instrumentación , Tecnología de Fibra Óptica/métodos , Resonancia por Plasmón de Superficie/instrumentación , Diseño de Equipo , Refractometría , Resonancia por Plasmón de Superficie/métodosRESUMEN
All-optical light amplitude tuning functionality is demonstrated in a layered tungsten disulfide (WS2) nanosheets coated microfiber (MF) structure. Due to the strong light-matter interactions between WS2 nanosheets and the evanescent field around the MF, a large variation in the transmitted power can be observed under both external and internal pump light excitations over a broadband spectrum (~100 nm). A power variation rate of ~0.3744 dB/mW is obtained under external violet pump light excitation, whereas the power variation rate of similar devices in the state of the art are usually less than 0.3 dB/mW. In terms of the response time, a moderate rise/fall time of â¼20.5/19.6 ms is achieved, which is mainly limited by the employed structure fabrication methods. These results indicate that the optical transmitted power of the WS2 coated MF can be modulated by different pump light with the power in the order of mW, thus the proposed device might have potential applications in all optical controllable devices and sensors, etc.
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A pure vortex beam carrying m-order orbital angular momentum (OAM) will be deformed when transmitting through a thin slab, and "neighboring" sideband {m + 1} and {m-1} modes will emerge. The emergence of the OAM sideband is accompanied with OAM-dependent Goos-Hänchen (GH) shift. When the energies carried by the {m} mode of the transmitted beam and by the sideband modes are identical, the OAM-dependent shifts reach their upper limits, |m|w0/2(|m| + 1)1/2, where w0 is the incident beam waist. The epsilon-near-zero metamaterial is found to be suitable to achieve the upper-limited OAM-dependent GH shifts. These findings provide a deeper insight into the beam shifts of vortex beams and have potential applications in the optical sensing, detection of OAM, and other OAM-based applications.
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The spin Hall effect (SHE) of light beams reflected from an air-chiral interface are investigated systematically. Due to the intrinsic chiral asymmetry of the medium, a horizontally polarized incident Gaussian beam will undergo asymmetric spin splitting, i.e., both the displacements and energies of two spin components of the reflected beam are different. One spin component can undergo large displacement near points of |rpp| = |rsp| (rpp and rsp are the Fresnel reflection coefficients), where the reflected beams are almost in circular polarization states. Moreover, for an incident beam carrying orbital angular momentum (OAM), the two spin components acquire additional OAM dependent shifts, which attribute to the asymmetric spin splitting. Thus, the asymmetric spin splitting of the reflected beam will vary with the incident OAM. These findings provide a deeper insight into the SHE of light, and they may have potential application in precision metrology.
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The effective mode index (EMI) of a graphene-coated side-polished fiber (GSPF) is calculated numerically. Whereby, the influences of graphene atom layer number, residual radius of SPF, light frequency, scattering rate of graphene, and temperature on the EMI are investigated comprehensively. Two types of mechanisms for the electro-optical absorption modulation are found for such GSPF-based modulator. One mechanism is Pauli blocking effect (PBE) and the other is plasmonic attenuation effect (PAE). With the optimal design parameters, a PBE-based modulator is theoretically predicted to have a 0.0072 dB/µm modulation depth, 2.92 V driving voltage swing, 6.35 nJ/bit power consumption, and 56.2 THz optical modulation bandwidth. It is also predicted that a PAE-based modulator could have a 0.0056 dB/µm modulation depth, 0.6 V driving voltage swing, 0.27 nJ/bit power consumption, and 2.5 THz optical modulation bandwidth. By further optimization, the modulator performance such as the relatively high power consumption and the narrow operation bandwidth can be improved. Owing to their seamless connection to optical fiber networks, the GSPF-based modulators have great potential to be used in fast and high-capacity optical communication systems.
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We propose an electro-optic mode deflection device based on an annealed proton exchange (APE) waveguide in lithium niobate, associated with isosceles-triangle-shaped array electrodes and a horn-shaped input waveguide. The input waveguide is tapered down to ensure that the output of the device has a good beam quality, i.e., a quasi-single mode in this case. This new device allows beam deflection at a relative low voltage and large deflection angle. At an APE-waveguide width of 80 µm, mode deflections of 0.265 and 0.240 µm/V are obtained for 1064 and 980 nm, respectively. This beam deflection device can be applied in high-speed optical switch, and beam smoothing of a high-power laser, etc.
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In this work, a sensitivity-enhanced surface plasmon resonance (SPR) sensor, which is integrated with MoSe2 as modification overlayer, is proposed and investigated. The sensor is constructed by physically depositing MoSe2 onto the surface of a conventional SPR sensor based on Krestchman configuration. Thanks to the commendable properties of MoSe2 including high carrier mobility, high refractive index (RI), large surface area, and so forth, adding an overlayer within a certain thickness can effectively improve the RI sensitivity. Experimental results show that, with the increased number of deposition cycles-which positively correlates with the duty ratio and the MoSe2 overlayer's thickness-the sensitivity at first increases, and then declines. The highest sensitivity of 2524.8 nm/RIU is achieved experimentally, which corresponds to the 2 deposition cycles. This shows an improvement of 36.3%, compared with the case without the MoSe2 modification. The ease of fabrication, efficiency of performance enhancement, and great potentials (such as the large surface area of MoSe2 for linking abundant functional groups) allow the method presented in this paper to contribute to the development of performance-enhanced SPR sensors for the biological, chemical, and medical fields.
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A novel fiber structure, coreless side-polished fiber (CSPF) that is wrapped by polydimethylsiloxane (PDMS), is demonstrated to be highly sensitive to temperature because of the high refractive index sensitivity of the CSPF and the large thermal optic coefficient of the PDMS. Our numerical and experimental results show that the several dips in the transmitted spectra of PDMSW-CSPF is originated from the multimode interference (MMI) in the CSPF and will blueshift with the increase of temperature. Furthermore, for such a PDMSW-CSPF, we investigate its temperature sensing characteristics and the influences of residual thickness (RT) and dip wavelength on the sensitivity both numerically and experimentally. In the temperature range of 30~85°C, the PDMSW-CSPF with RT = 43.26 µm exhibits a high temperature sensitivity of -0.4409 nm/°C, the high linearity of 0.9974, and the high stability with low standard deviation of 0.141 nm. Moreover, in the cycle experiments, where the environmental temperature was set to automatically increase and then decrease, the PDMSW-CSPF exhibits a low relative deviation of sensitivity (RSD) of down to ± 0.068%. Here, the RSD is defined as the ratio of sensitivity deviation to the average sensitivity measured in the heating/cooling cycle experiments. The lower RSD indicates that PDMSW-CSPF has better reversibility than other fiber structure. The investigations also show that the sensitivity of the PDMSW-CSPF could be enhanced further by reducing the residual thickness and choosing the dip at a longer wavelength.
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All-optical light-control-light functionality is realized in a layered tungsten disulfide (WS2) nanosheet coated microfiber knot resonator (MKR) structure. Mainly due to the photon generated excitons induced refractive index variation in WS2 nanosheets, a large variation in the transmitted power (∆T) can be observed under external violet/red laser excitation. The ∆T variation rates can reach up to ~0.4 dB/mW under violet pump light excitation whereas the state of the art light-control-light structures usually has a variation rate of less than 0.25 dB/mW. In terms of the response time, the averaged rise/fall time is ~0.12/0.1 s. The demonstrated structure has the advantages of easy fabrication, low cost and high sensitivity, therefore, it might be a promising candidate for building future all-fiber-optics based functional devices and all-optical circuitry.