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1.

Chromatin conformational changes at human satellite II contribute to the senescence phenotype in the tumor microenvironment.

Miyata, Kenichi; Zhou, Xiangyu; Nishio, Mika; Hanyu, Aki; Chiba, Masatomo; Kawasaki, Hiroko; Osako, Tomo; Takeuchi, Kengo; Ohno, Shinji; Ueno, Takayuki; Maruyama, Reo; Takahashi, Akiko.

Proc Natl Acad Sci U S A ; 120(32): e2305046120, 2023 08 08.

Artículo en Inglés | MEDLINE | ID: mdl-37523559

2.

Visualizing spatiotemporal dynamics of multicellular cell-cycle progression.

Sakaue-Sawano, Asako; Kurokawa, Hiroshi; Morimura, Toshifumi; Hanyu, Aki; Hama, Hiroshi; Osawa, Hatsuki; Kashiwagi, Saori; Fukami, Kiyoko; Miyata, Takaki; Miyoshi, Hiroyuki; Imamura, Takeshi; Ogawa, Masaharu; Masai, Hisao; Miyawaki, Atsushi.

Cell ; 132(3): 487-98, 2008 Feb 08.

Artículo en Inglés | MEDLINE | ID: mdl-18267078

3.

Identification of Novel Senescent Markers in Small Extracellular Vesicles.

Misawa, Tomoka; Hitomi, Kazuhiro; Miyata, Kenichi; Tanaka, Yoko; Fujii, Risa; Chiba, Masatomo; Loo, Tze Mun; Hanyu, Aki; Kawasaki, Hiroko; Kato, Hisaya; Maezawa, Yoshiro; Yokote, Koutaro; Nakamura, Asako J; Ueda, Koji; Yaegashi, Nobuo; Takahashi, Akiko.

Int J Mol Sci ; 24(3)2023 Jan 26.

Artículo en Inglés | MEDLINE | ID: mdl-36768745

4.

Bioluminescent system for dynamic imaging of cell and animal behavior.

Hara-Miyauchi, Chikako; Tsuji, Osahiko; Hanyu, Aki; Okada, Seiji; Yasuda, Akimasa; Fukano, Takashi; Akazawa, Chihiro; Nakamura, Masaya; Imamura, Takeshi; Matsuzaki, Yumi; Okano, Hirotaka James; Miyawaki, Atsushi; Okano, Hideyuki.

Biochem Biophys Res Commun ; 419(2): 188-93, 2012 Mar 09.

Artículo en Inglés | MEDLINE | ID: mdl-22333570

5.

Hepatocyte growth factor derived from senescent cells attenuates cell competition-induced apical elimination of oncogenic cells.

Igarashi, Nanase; Miyata, Kenichi; Loo, Tze Mun; Chiba, Masatomo; Hanyu, Aki; Nishio, Mika; Kawasaki, Hiroko; Zheng, Hao; Toyokuni, Shinya; Kon, Shunsuke; Moriyama, Keiji; Fujita, Yasuyuki; Takahashi, Akiko.

Nat Commun ; 13(1): 4157, 2022 07 18.

Artículo en Inglés | MEDLINE | ID: mdl-35851277

6.

Estrogen inhibits transforming growth factor beta signaling by promoting Smad2/3 degradation.

Ito, Ichiaki; Hanyu, Aki; Wayama, Mitsutoshi; Goto, Natsuka; Katsuno, Yoko; Kawasaki, Shohei; Nakajima, Yuka; Kajiro, Masashi; Komatsu, Yoko; Fujimura, Akiko; Hirota, Ryuichi; Murayama, Akiko; Kimura, Keiji; Imamura, Takeshi; Yanagisawa, Junn.

J Biol Chem ; 285(19): 14747-55, 2010 May 07.

Artículo en Inglés | MEDLINE | ID: mdl-20207742

7.

Functional in vivo optical imaging of tumor angiogenesis, growth, and metastasis prevented by administration of anti-human VEGF antibody in xenograft model of human fibrosarcoma HT1080 cells.

Hanyu, Aki; Kojima, Kiyotsugu; Hatake, Kiyohiko; Nomura, Kimie; Murayama, Hironori; Ishikawa, Yuichi; Miyata, Satoshi; Ushijima, Masaru; Matsuura, Masaaki; Ogata, Etsuro; Miyazawa, Keiji; Imamura, Takeshi.

Cancer Sci ; 100(11): 2085-92, 2009 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-19719773

8.

Transforming growth factor-beta promotes survival of mammary carcinoma cells through induction of antiapoptotic transcription factor DEC1.

Ehata, Shogo; Hanyu, Aki; Hayashi, Makoto; Aburatani, Hiroyuki; Kato, Yukio; Fujime, Makoto; Saitoh, Masao; Miyazawa, Keiji; Imamura, Takeshi; Miyazono, Kohei.

Cancer Res ; 67(20): 9694-703, 2007 Oct 15.

Artículo en Inglés | MEDLINE | ID: mdl-17942899

9.

[TGF-beta signaling during bone metastasis of breast cancer and in-vivo imaging].

Imamura, Takeshi; Hanyu, Aki.

Clin Calcium ; 18(4): 460-5, 2008 Apr.

Artículo en Japonés | MEDLINE | ID: mdl-18379027

10.

Publisher Correction: Exosomes maintain cellular homeostasis by excreting harmful DNA from cells.

Takahashi, Akiko; Okada, Ryo; Nagao, Koji; Kawamata, Yuka; Hanyu, Aki; Yoshimoto, Shin; Takasugi, Masaki; Watanabe, Sugiko; Kanemaki, Masato T; Obuse, Chikashi; Hara, Eiji.

Nat Commun ; 9(1): 4109, 2018 10 08.

Artículo en Inglés | MEDLINE | ID: mdl-30294002

11.

p16^Ink4a and p21^Cip1/Waf1 promote tumour growth by enhancing myeloid-derived suppressor cells chemotaxis.

Okuma, Atsushi; Hanyu, Aki; Watanabe, Sugiko; Hara, Eiji.

Nat Commun ; 8(1): 2050, 2017 12 12.

Artículo en Inglés | MEDLINE | ID: mdl-29234059

12.

Exosomes maintain cellular homeostasis by excreting harmful DNA from cells.

Takahashi, Akiko; Okada, Ryo; Nagao, Koji; Kawamata, Yuka; Hanyu, Aki; Yoshimoto, Shin; Takasugi, Masaki; Watanabe, Sugiko; Kanemaki, Masato T; Obuse, Chikashi; Hara, Eiji.

Nat Commun ; 8: 15287, 2017 05 16.

Artículo en Inglés | MEDLINE | ID: mdl-28508895

13.

SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cells.

Matsuyama, Shigeo; Iwadate, Manabu; Kondo, Miki; Saitoh, Masao; Hanyu, Aki; Shimizu, Kiyoshi; Aburatani, Hiroyuki; Mishima, Hiromu K; Imamura, Takeshi; Miyazono, Kohei; Miyazawa, Keiji.

Cancer Res ; 63(22): 7791-8, 2003 Nov 15.

Artículo en Inglés | MEDLINE | ID: mdl-14633705

14.

[In vivo optical imaging of cancer].

Imamura, Takeshi; Hanyu, Aki; Hikita, Atsuhiko.

Seikagaku ; 83(5): 406-9, 2011 May.

Artículo en Japonés | MEDLINE | ID: mdl-21706878

15.

Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice.

Sato, Seidai; Kawamata, Yuka; Takahashi, Akiko; Imai, Yoshinori; Hanyu, Aki; Okuma, Atsushi; Takasugi, Masaki; Yamakoshi, Kimi; Sorimachi, Hiroyuki; Kanda, Hiroaki; Ishikawa, Yuichi; Sone, Saburo; Nishioka, Yasuhiko; Ohtani, Naoko; Hara, Eiji.

Nat Commun ; 6: 7035, 2015 Apr 29.

Artículo en Inglés | MEDLINE | ID: mdl-25923845

16.

Crosstalk between the Rb pathway and AKT signaling forms a quiescence-senescence switch.

Imai, Yoshinori; Takahashi, Akiko; Hanyu, Aki; Hori, Satoshi; Sato, Seidai; Naka, Kazuhito; Hirao, Atsushi; Ohtani, Naoko; Hara, Eiji.

Cell Rep ; 7(1): 194-207, 2014 Apr 10.

Artículo en Inglés | MEDLINE | ID: mdl-24703840

17.

ZSTK474, a specific phosphatidylinositol 3-kinase inhibitor, induces G1 arrest of the cell cycle in vivo.

Dan, Shingo; Okamura, Mutsumi; Mukai, Yumiko; Yoshimi, Hisashi; Inoue, Yasumichi; Hanyu, Aki; Sakaue-Sawano, Asako; Imamura, Takeshi; Miyawaki, Atsushi; Yamori, Takao.

Eur J Cancer ; 48(6): 936-43, 2012 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-22088482

18.

SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells.

Takahata, Mami; Inoue, Yasumichi; Tsuda, Hitoshi; Imoto, Issei; Koinuma, Daizo; Hayashi, Makoto; Ichikura, Takashi; Yamori, Takao; Nagasaki, Koichi; Yoshida, Mika; Matsuoka, Masao; Morishita, Kazuhiro; Yuki, Keiko; Hanyu, Aki; Miyazawa, Keiji; Inazawa, Johji; Miyazono, Kohei; Imamura, Takeshi.

J Biol Chem ; 284(5): 3334-3344, 2009 Jan 30.

Artículo en Inglés | MEDLINE | ID: mdl-19049980

19.

Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells.

Fukunaga, Erina; Inoue, Yasumichi; Komiya, Setsuro; Horiguchi, Kana; Goto, Kouichiro; Saitoh, Masao; Miyazawa, Keiji; Koinuma, Daizo; Hanyu, Aki; Imamura, Takeshi.

J Biol Chem ; 283(51): 35660-7, 2008 Dec 19.

Artículo en Inglés | MEDLINE | ID: mdl-18927080

20.

Ki26894, a novel transforming growth factor-beta type I receptor kinase inhibitor, inhibits in vitro invasion and in vivo bone metastasis of a human breast cancer cell line.

Ehata, Shogo; Hanyu, Aki; Fujime, Makoto; Katsuno, Yoko; Fukunaga, Erina; Goto, Kouichiro; Ishikawa, Yuichi; Nomura, Kimie; Yokoo, Hiroshi; Shimizu, Toshiyuki; Ogata, Etsuro; Miyazono, Kohei; Shimizu, Kiyoshi; Imamura, Takeshi.

Cancer Sci ; 98(1): 127-33, 2007 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-17129361

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