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1.
Discovery of XL888: a novel tropane-derived small molecule inhibitor of HSP90.
Bioorg Med Chem Lett
; 22(17): 5396-404, 2012 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22877636
2.
EXEL-7647 inhibits mutant forms of ErbB2 associated with lapatinib resistance and neoplastic transformation.
Clin Cancer Res
; 14(8): 2465-75, 2008 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18413839
3.
Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer.
Oncotarget
; 9(37): 24787-24800, 2018 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29872506
4.
Fatty acid synthase - Modern tumor cell biology insights into a classical oncology target.
Pharmacol Ther
; 177: 23-31, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28202364
5.
FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and Gene Expression.
EBioMedicine
; 16: 51-62, 2017 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-28159572
6.
Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase Induces Apoptosis in Tumor Cells by Remodeling Cell Membranes, Inhibiting Signaling Pathways, and Reprogramming Gene Expression.
EBioMedicine
; 2(8): 808-24, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26425687
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