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1.
J Infect ; 81(1): 147-178, 2020 07.
Artículo en Inglés | MEDLINE | ID: mdl-32205138

RESUMEN

Since its identification in December 2019, SARS-CoV-2 has infected 125,048 persons globally with cases identified in 118 countries across all continents. We report on the Scottish index case of SARS-CoV-2 infection, the virus causing COVID-19.


Asunto(s)
Infecciones por Coronavirus , Coronavirus , Neumonía Viral , Coronavirus Relacionado al Síndrome Respiratorio Agudo Severo , Betacoronavirus , COVID-19 , Humanos , Pandemias , SARS-CoV-2 , Escocia , Reino Unido
2.
Neurology ; 91(3): e258-e267, 2018 07 17.
Artículo en Inglés | MEDLINE | ID: mdl-29950436

RESUMEN

OBJECTIVE: To assess the reliability and usefulness of an EEG-based brain-computer interface (BCI) for patients with advanced amyotrophic lateral sclerosis (ALS) who used it independently at home for up to 18 months. METHODS: Of 42 patients consented, 39 (93%) met the study criteria, and 37 (88%) were assessed for use of the Wadsworth BCI. Nine (21%) could not use the BCI. Of the other 28, 27 (men, age 28-79 years) (64%) had the BCI placed in their homes, and they and their caregivers were trained to use it. Use data were collected by Internet. Periodic visits evaluated BCI benefit and burden and quality of life. RESULTS: Over subsequent months, 12 (29% of the original 42) left the study because of death or rapid disease progression and 6 (14%) left because of decreased interest. Fourteen (33%) completed training and used the BCI independently, mainly for communication. Technical problems were rare. Patient and caregiver ratings indicated that BCI benefit exceeded burden. Quality of life remained stable. Of those not lost to the disease, half completed the study; all but 1 patient kept the BCI for further use. CONCLUSION: The Wadsworth BCI home system can function reliably and usefully when operated by patients in their homes. BCIs that support communication are at present most suitable for people who are severely disabled but are otherwise in stable health. Improvements in BCI convenience and performance, including some now underway, should increase the number of people who find them useful and the extent to which they are used.


Asunto(s)
Esclerosis Amiotrófica Lateral/terapia , Interfaces Cerebro-Computador/normas , Servicios de Atención de Salud a Domicilio/normas , Autocuidado/normas , Terapia Asistida por Computador/normas , United States Department of Veterans Affairs/normas , Adulto , Anciano , Esclerosis Amiotrófica Lateral/diagnóstico , Esclerosis Amiotrófica Lateral/fisiopatología , Interfaces Cerebro-Computador/tendencias , Electroencefalografía/normas , Electroencefalografía/tendencias , Servicios de Atención de Salud a Domicilio/tendencias , Humanos , Masculino , Persona de Mediana Edad , Autocuidado/tendencias , Terapia Asistida por Computador/tendencias , Estados Unidos/epidemiología , United States Department of Veterans Affairs/tendencias
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