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1.
Acid ceramidase involved in pathogenic cascade leading to accumulation of α-synuclein in iPSC model of GBA1-associated Parkinson's disease.
Hum Mol Genet
; 32(11): 1888-1900, 2023 05 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-36752535
2.
Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors.
Cell
; 136(5): 964-77, 2009 Mar 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-19269371
3.
Cell type-specific lipid storage changes in Parkinson's disease patient brains are recapitulated by experimental glycolipid disturbance.
Proc Natl Acad Sci U S A
; 117(44): 27646-27654, 2020 11 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33060302
4.
Glycosphingolipid metabolism and its role in ageing and Parkinson's disease.
Glycoconj J
; 39(1): 39-53, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34757540
5.
Mitochondrial clearance and maturation of autophagosomes are compromised in LRRK2 G2019S familial Parkinson's disease patient fibroblasts.
Hum Mol Genet
; 28(19): 3232-3243, 2019 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31261377
6.
Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells.
Stem Cells
; 37(10): 1293-1306, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31381839
7.
Lipid and immune abnormalities causing age-dependent neurodegeneration and Parkinson's disease.
J Neuroinflammation
; 16(1): 153, 2019 Jul 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-31331333
8.
α-Synuclein-induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models.
Proc Natl Acad Sci U S A
; 113(7): 1931-6, 2016 Feb 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-26839413
9.
Increased motor neuron resilience by small molecule compounds that regulate IGF-II expression.
Neurobiol Dis
; 110: 218-230, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29113829
10.
The glycoprotein GPNMB is selectively elevated in the substantia nigra of Parkinson's disease patients and increases after lysosomal stress.
Neurobiol Dis
; 120: 1-11, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30149180
11.
Progressive axonal transport and synaptic protein changes correlate with behavioral and neuropathological abnormalities in the heterozygous Q175 KI mouse model of Huntington's disease.
Hum Mol Genet
; 23(17): 4510-27, 2014 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24728190
12.
Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons.
Neurobiol Dis
; 82: 495-503, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26392287
13.
Enhanced ubiquitin-dependent degradation by Nedd4 protects against α-synuclein accumulation and toxicity in animal models of Parkinson's disease.
Neurobiol Dis
; 64: 79-87, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24388974
14.
LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction.
Neurobiol Dis
; 62: 381-6, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24148854
15.
Improved cell therapy protocols for Parkinson's disease based on differentiation efficiency and safety of hESC-, hiPSC-, and non-human primate iPSC-derived dopaminergic neurons.
Stem Cells
; 31(8): 1548-62, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23666606
16.
Motor impairments, striatal degeneration, and altered dopamine-glutamate interplay in mice lacking PSD-95.
J Neurogenet
; 28(1-2): 98-111, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24702501
17.
Transcript expression levels of full-length alpha-synuclein and its three alternatively spliced variants in Parkinson's disease brain regions and in a transgenic mouse model of alpha-synuclein overexpression.
Mol Cell Neurosci
; 49(2): 230-9, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22155155
18.
Sorting the wheat from the chaff in dopamine neuron-based cell therapies.
Proc Natl Acad Sci U S A
; 112(15): 4512-3, 2015 Apr 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-25848026
19.
Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats.
Proc Natl Acad Sci U S A
; 107(36): 15921-6, 2010 Sep 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-20798034
20.
Loss of Lipid Carrier ApoE Exacerbates Brain Glial and Inflammatory Responses after Lysosomal GBA1 Inhibition.
Cells
; 12(21)2023 11 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-37947642