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1.

Mapping genotypes to chromatin accessibility profiles in single cells.

Izzo, Franco; Myers, Robert M; Ganesan, Saravanan; Mekerishvili, Levan; Kottapalli, Sanjay; Prieto, Tamara; Eton, Elliot O; Botella, Theo; Dunbar, Andrew J; Bowman, Robert L; Sotelo, Jesus; Potenski, Catherine; Mimitou, Eleni P; Stahl, Maximilian; El Ghaity-Beckley, Sebastian; Arandela, JoAnn; Raviram, Ramya; Choi, Daniel C; Hoffman, Ronald; Chaligné, Ronan; Abdel-Wahab, Omar; Smibert, Peter; Ghobrial, Irene M; Scandura, Joseph M; Marcellino, Bridget; Levine, Ross L; Landau, Dan A.

Nature ; 629(8014): 1149-1157, 2024 May.

Artículo en Inglés | MEDLINE | ID: mdl-38720070

2.

Somatic mutations and cell identity linked by Genotyping of Transcriptomes.

Nam, Anna S; Kim, Kyu-Tae; Chaligne, Ronan; Izzo, Franco; Ang, Chelston; Taylor, Justin; Myers, Robert M; Abu-Zeinah, Ghaith; Brand, Ryan; Omans, Nathaniel D; Alonso, Alicia; Sheridan, Caroline; Mariani, Marisa; Dai, Xiaoguang; Harrington, Eoghan; Pastore, Alessandro; Cubillos-Ruiz, Juan R; Tam, Wayne; Hoffman, Ronald; Rabadan, Raul; Scandura, Joseph M; Abdel-Wahab, Omar; Smibert, Peter; Landau, Dan A.

Nature ; 571(7765): 355-360, 2019 07.

Artículo en Inglés | MEDLINE | ID: mdl-31270458

3.

A BAX door to venetoclax resistance.

Izzo, Franco; Landau, Dan A.

Blood ; 139(8): 1124-1126, 2022 02 24.

Artículo en Inglés | MEDLINE | ID: mdl-35201333

4.

Genetic and epigenetic determinants of B-cell lymphoma evolution.

Izzo, Franco; Landau, Dan A.

Curr Opin Hematol ; 23(4): 392-401, 2016 07.

Artículo en Inglés | MEDLINE | ID: mdl-27135978

5.

Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth.

Izzo, Franco; Mercogliano, Florencia; Venturutti, Leandro; Tkach, Mercedes; Inurrigarro, Gloria; Schillaci, Roxana; Cerchietti, Leandro; Elizalde, Patricia V; Proietti, Cecilia J.

Breast Cancer Res ; 16(6): 491, 2014 Dec 06.

Artículo en Inglés | MEDLINE | ID: mdl-25479686

6.

Jak2V617F Reversible Activation Shows Its Essential Requirement in Myeloproliferative Neoplasms.

Dunbar, Andrew J; Bowman, Robert L; Park, Young C; O'Connor, Kavi; Izzo, Franco; Myers, Robert M; Karzai, Abdul; Zaroogian, Zachary; Kim, Won Jun; Fernández-Maestre, Inés; Waarts, Michael R; Nazir, Abbas; Xiao, Wenbin; Codilupi, Tamara; Brodsky, Max; Farina, Mirko; Cai, Louise; Cai, Sheng F; Wang, Benjamin; An, Wenbin; Yang, Julie L; Mowla, Shoron; Eisman, Shira E; Hanasoge Somasundara, Amritha Varshini; Glass, Jacob L; Mishra, Tanmay; Houston, Remie; Guzzardi, Emily; Martinez Benitez, Anthony R; Viny, Aaron D; Koche, Richard P; Meyer, Sara C; Landau, Dan A; Levine, Ross L.

Cancer Discov ; 14(5): 737-751, 2024 May 01.

Artículo en Inglés | MEDLINE | ID: mdl-38230747

7.

MAVS signaling is required for preventing persistent chikungunya heart infection and chronic vascular tissue inflammation.

Noval, Maria G; Spector, Sophie N; Bartnicki, Eric; Izzo, Franco; Narula, Navneet; Yeung, Stephen T; Damani-Yokota, Payal; Dewan, M Zahidunnabi; Mezzano, Valeria; Rodriguez-Rodriguez, Bruno A; Loomis, Cynthia; Khanna, Kamal M; Stapleford, Kenneth A.

Nat Commun ; 14(1): 4668, 2023 08 03.

Artículo en Inglés | MEDLINE | ID: mdl-37537212

8.

Influence of conformationally restricted pyrimidines on the activity of 10-23 DNAzymes.

Robaldo, Laura; Izzo, Franco; Dellafiore, María; Proietti, Cecilia; Elizalde, Patricia V; Montserrat, Javier M; Iribarren, Adolfo M.

Bioorg Med Chem ; 20(8): 2581-6, 2012 Apr 15.

Artículo en Inglés | MEDLINE | ID: mdl-22429508

9.

Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation.

Nam, Anna S; Dusaj, Neville; Izzo, Franco; Murali, Rekha; Myers, Robert M; Mouhieddine, Tarek H; Sotelo, Jesus; Benbarche, Salima; Waarts, Michael; Gaiti, Federico; Tahri, Sabrin; Levine, Ross; Abdel-Wahab, Omar; Godley, Lucy A; Chaligne, Ronan; Ghobrial, Irene; Landau, Dan A.

Nat Genet ; 54(10): 1514-1526, 2022 10.

Artículo en Inglés | MEDLINE | ID: mdl-36138229

10.

Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction.

Gómez-Salinero, Jesus Maria; Izzo, Franco; Lin, Yang; Houghton, Sean; Itkin, Tomer; Geng, Fuqiang; Bram, Yaron; Adelson, Robert P; Lu, Tyler M; Inghirami, Giorgio; Xiang, Jenny Zhaoying; Lis, Raphael; Redmond, David; Schreiner, Ryan; Rabbany, Sina Y; Landau, Dan A; Schwartz, Robert E; Rafii, Shahin.

Cell Stem Cell ; 29(4): 593-609.e7, 2022 04 07.

Artículo en Inglés | MEDLINE | ID: mdl-35364013

11.

Halting ErbB-2 isoforms retrograde transport to the nucleus as a new theragnostic approach for triple-negative breast cancer.

Madera, Santiago; Izzo, Franco; Chervo, María F; Dupont, Agustina; Chiauzzi, Violeta A; Bruni, Sofia; Petrillo, Ezequiel; Merin, Sharon S; De Martino, Mara; Montero, Diego; Levit, Claudio; Lebersztein, Gabriel; Anfuso, Fabiana; Roldán Deamicis, Agustina; Mercogliano, María F; Proietti, Cecilia J; Schillaci, Roxana; Elizalde, Patricia V; Cordo Russo, Rosalía I.

Cell Death Dis ; 13(5): 447, 2022 05 09.

Artículo en Inglés | MEDLINE | ID: mdl-35534460

12.

Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states.

Chaligne, Ronan; Gaiti, Federico; Silverbush, Dana; Schiffman, Joshua S; Weisman, Hannah R; Kluegel, Lloyd; Gritsch, Simon; Deochand, Sunil D; Gonzalez Castro, L Nicolas; Richman, Alyssa R; Klughammer, Johanna; Biancalani, Tommaso; Muus, Christoph; Sheridan, Caroline; Alonso, Alicia; Izzo, Franco; Park, Jane; Rozenblatt-Rosen, Orit; Regev, Aviv; Suvà, Mario L; Landau, Dan A.

Nat Genet ; 53(10): 1469-1479, 2021 10.

Artículo en Inglés | MEDLINE | ID: mdl-34594037

13.

Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells.

Wesely, Josephine; Kotini, Andriana G; Izzo, Franco; Luo, Hanzhi; Yuan, Han; Sun, Jun; Georgomanoli, Maria; Zviran, Asaf; Deslauriers, André G; Dusaj, Neville; Nimer, Stephen D; Leslie, Christina; Landau, Dan A; Kharas, Michael G; Papapetrou, Eirini P.

Cell Rep ; 31(9): 107688, 2020 06 02.

Artículo en Inglés | MEDLINE | ID: mdl-32492433

14.

Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer.

Yomtoubian, Shira; Lee, Sharrell B; Verma, Akanksha; Izzo, Franco; Markowitz, Geoffrey; Choi, Hyejin; Cerchietti, Leandro; Vahdat, Linda; Brown, Kristy A; Andreopoulou, Eleni; Elemento, Olivier; Chang, Jenny; Inghirami, Giorgio; Gao, Dingcheng; Ryu, Seongho; Mittal, Vivek.

Cell Rep ; 30(3): 755-770.e6, 2020 01 21.

Artículo en Inglés | MEDLINE | ID: mdl-31968251

15.

DNA methylation disruption reshapes the hematopoietic differentiation landscape.

Izzo, Franco; Lee, Stanley C; Poran, Asaf; Chaligne, Ronan; Gaiti, Federico; Gross, Baptiste; Murali, Rekha R; Deochand, Sunil D; Ang, Chelston; Jones, Philippa Wyndham; Nam, Anna S; Kim, Kyu-Tae; Kothen-Hill, Steven; Schulman, Rafael C; Ki, Michelle; Lhoumaud, Priscillia; Skok, Jane A; Viny, Aaron D; Levine, Ross L; Kenigsberg, Ephraim; Abdel-Wahab, Omar; Landau, Dan A.

Nat Genet ; 52(4): 378-387, 2020 04.

Artículo en Inglés | MEDLINE | ID: mdl-32203468

16.

Canonical ErbB-2 isoform and ErbB-2 variant c located in the nucleus drive triple negative breast cancer growth.

Chervo, María F; Cordo Russo, Rosalía I; Petrillo, Ezequiel; Izzo, Franco; De Martino, Mara; Bellora, Nicolás; Cenciarini, Mauro E; Chiauzzi, Violeta A; Santa María de la Parra, Lucía; Pereyra, Matías G; Güttlein, Leandro N; Podhajcer, Osvaldo L; Daniotti, José L; Dupont, Agustina; Barchuk, Sabrina; Figurelli, Silvina; Lopez Della Vecchia, Daniel; Roa, Juan C; Guzmán, Pablo; Proietti, Cecilia J; Schillaci, Roxana; Elizalde, Patricia V.

Oncogene ; 39(39): 6245-6262, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32843720

17.

Nuclear PDCD4 Expression Defines a Subset of Luminal B-Like Breast Cancers with Good Prognosis.

Madera, Santiago; Chervo, María F; Chiauzzi, Violeta A; Pereyra, Matías G; Venturutti, Leandro; Izzo, Franco; Roldán Deamicis, Agustina; Guzman, Pablo; Dupont, Agustina; Roa, Juan Carlos; Cenciarini, Mauro E; Barchuk, Sabrina; Figurelli, Silvina; Lopez Della Vecchia, Daniel; Levit, Claudio; Lebersztein, Gabriel; Anfuso, Fabiana; Castiglioni, Teresa; Cortese, Eduardo; Ares, Sandra; Deza, Ernesto Gil; Gercovich, Felipe G; Proietti, Cecilia J; Schillaci, Roxana; Cordo Russo, Rosalía I; Elizalde, Patricia V.

Horm Cancer ; 11(5-6): 218-239, 2020 10.

Artículo en Inglés | MEDLINE | ID: mdl-32632815

18.

EpiMethylTag: simultaneous detection of ATAC-seq or ChIP-seq signals with DNA methylation.

Lhoumaud, Priscillia; Sethia, Gunjan; Izzo, Franco; Sakellaropoulos, Theodore; Snetkova, Valentina; Vidal, Simon; Badri, Sana; Cornwell, Macintosh; Di Giammartino, Dafne Campigli; Kim, Kyu-Tae; Apostolou, Effie; Stadtfeld, Matthias; Landau, Dan Avi; Skok, Jane.

Genome Biol ; 20(1): 248, 2019 11 21.

Artículo en Inglés | MEDLINE | ID: mdl-31752933

19.

m⁶A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment.

Cheng, Yuanming; Luo, Hanzhi; Izzo, Franco; Pickering, Brian F; Nguyen, Diu; Myers, Robert; Schurer, Alexandra; Gourkanti, Saroj; Brüning, Jens C; Vu, Ly P; Jaffrey, Samie R; Landau, Dan A; Kharas, Michael G.

Cell Rep ; 28(7): 1703-1716.e6, 2019 08 13.

Artículo en Inglés | MEDLINE | ID: mdl-31412241

20.

Correction: Halting ErbB-2 isoforms retrograde transport to the nucleus as a new theragnostic approach for triple-negative breast cancer.