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1.
Opt Express ; 29(13): 20786-20794, 2021 Jun 21.
Artículo en Inglés | MEDLINE | ID: mdl-34266160

RESUMEN

Spectral interferometry is utilized in a wide range of biomedical and scientific applications and metrology. Retrieving the magnitude and phase of the complex electric field from the interferogram is central to all its applications. We report a spectral interferometry system that utilizes a neural network to infer the magnitude and phase of femtosecond interferograms directly from the measured single-shot interference patterns and compare its performance with the widely used Hilbert transform. Our approach does not require apriori knowledge of the shear frequency, and achieves higher accuracy under our experimental conditions. To train the network, we introduce an experimental technique that generates a large number of femtosecond interferograms with known (labeled) phase and magnitude profiles. While the profiles for these pulses are digitally generated, they obey causality by satisfying the Kramer-Kronig relation. This technique is resilient against nonlinear optical distortions, quantization noise, and the sampling rate limit of the backend digitizer - valuable properties that relax instrument complexity and cost.

2.
Opt Lett ; 46(3): 500-503, 2021 Feb 01.
Artículo en Inglés | MEDLINE | ID: mdl-33528394

RESUMEN

Dispersion management is critical in many optical applications, whether to reduce impairments in fiber optic communication or chirp pulse amplification, or to create time stretch instruments for single-shot continuous recording of fast phenomena. The most common solutions for achieving large dispersion with low loss include dispersion compensation fiber, fiber Bragg grating, and diffraction grating pairs. Such dispersive elements have finite operational bandwidth, limited total dispersion, or insufficient power handling. In this Letter, we demonstrate a new, to the best of our knowledge, implementation of the chromo-modal dispersion device based on a silicon waveguide slab that addresses these limitations. The device provides extremely large dispersion with a widely tunable spectrum. We also propose a new time-stretch spectrometer where the absorption cell simultaneously provides spectrum-to-time mapping for fast single-shot spectroscopy.

3.
Opt Express ; 27(16): 23321-23335, 2019 Aug 05.
Artículo en Inglés | MEDLINE | ID: mdl-31510612

RESUMEN

With the ever-increasing need for bandwidth in data centers and 5G mobile communications, technologies for rapid characterization of wide-band devices are in high demand. We report an instrument for extremely fast characterization of the electronic and optoelectronic devices with 27 ns frequency-response acquisition time at the effective sampling rate of 2.5 Tera-sample/s and an ultra-low effective timing jitter of 5.4 fs. This instrument features automated digital signal processing algorithms including time-series segmentation and frame alignment, impulse localization and Tikhonov regularized deconvolution for single-shot impulse and frequency response measurements. The system is based on the photonic time-stretch and features phase diversity to eliminate frequency fading and extend the bandwidth of the instrument.

4.
Opt Lett ; 44(8): 1952-1955, 2019 Apr 15.
Artículo en Inglés | MEDLINE | ID: mdl-30985783

RESUMEN

Originally introduced in 2005 for high-speed optical coherence tomography, the rapidly wavelength-swept Fourier-domain mode-locked (FDML) laser still, to this day, enables highest imaging speeds through a very high-speed spectral tuning capability. The FDML laser achieves a tuning bandwidth of over 1/10th of its center wavelength and can sweep this entire bandwidth in less than a microsecond. Interestingly, even though it covers a very broad spectral range, instantaneously it has a narrow spectral linewidth that puts it in a unique space compared to other high-speed broadband laser sources, e.g., mode-locked lasers or supercontinuum sources. Although it has been applied for nonlinear Raman spectroscopy and imaging, a current drawback of this continuous wave laser is the relatively low instantaneous power of 10-100 mW. Here, we report the combination of an FDML laser with a master oscillator power amplifier (MOPA) architecture to increase the instantaneous power of the FDML for nonlinear optical interactions. The output of an FDML laser around 1060 nm is modulated to short pulses by using an electro-optic amplitude modulator and subsequently amplified using ytterbium-doped fiber amplifiers (YDFAs). This generates a spectral rainbow of 65 picosecond pulses, where each pulse has a distinct, monochromatic wavelength. The instantaneous power can be adjusted by the YDFAs to reach nonlinear optical excitation regimes. This wavelength-swept FDML-MOPA laser will have a vast range of applications in, e.g., nonlinear optics, spectroscopy, imaging, and sensing.

5.
Opt Lett ; 44(24): 5913-5916, 2019 Dec 15.
Artículo en Inglés | MEDLINE | ID: mdl-32628184

RESUMEN

Wavelength-swept lasers enable high-speed measurements in absorption spectroscopy, Raman spectroscopy, nonlinear Raman hyperspectral microscopy, rapid confocal microscopy, short impulse generation, and most importantly for high-speed optical coherence tomography, with speeds up to video-rate volumetric imaging. Recently, we introduced a pulsed wavelength-swept laser based on the Fourier domain mode-locked (FDML) laser principle combined with a master-oscillator power amplifier (MOPA) architecture. The high peak powers reached with this laser enabled rapid two-photon microscopy and two-photon fluorescence lifetime microscopy and high-speed light detection and ranging measurements. Here, we present the extension of this laser into the visible wavelength range by frequency doubling the output from 1064 nm to 532 nm via second harmonic generation in a deuterated potassium dihydrogen phosphate crystal. The result is a wavelength-swept laser source around 532 nm that outputs a pulse train of distinct, almost monochromatic wavelengths at an 88 MHz pulse repetition rate and 342 kHz sweep repetition rate. This swept-source laser in the visible can open up new research applications in spectroscopy, metrology, sensing, and high-speed imaging.

6.
Opt Lett ; 43(8): 1862-1865, 2018 Apr 15.
Artículo en Inglés | MEDLINE | ID: mdl-29652384

RESUMEN

Experimentally, we demonstrate, to the best of our knowledge, the first observation of periodic spectrum changing via soliton explosion in a passively mode-locked fiber laser by a nonlinear polarization evolution. Using time stretch to capture 7220 consecutive single-shot spectra over a 100 µs time window in real time, the soliton explosions appear in a transition between two different mode-locking states. Simultaneous measurements of spectrum and pulse energy at three different output points in the laser cavity show that the soliton explosion's dynamics are related to residual dispersion. This study improves the understanding of pulse formation and evolution in the unstable mode-locking regime of lasers.

7.
Opt Lett ; 41(6): 1273-6, 2016 Mar 15.
Artículo en Inglés | MEDLINE | ID: mdl-26977687

RESUMEN

Optical computing accelerators help alleviate bandwidth and power consumption bottlenecks in electronics. We show an approach to implementing logarithmic-type analog co-processors in silicon photonics and use it to perform the exponentiation operation and the recovery of a signal in the presence of multiplicative distortion. The function is realized by exploiting nonlinear-absorption-enhanced Raman amplification saturation in a silicon waveguide.

8.
Appl Opt ; 55(30): 8406-8412, 2016 Oct 20.
Artículo en Inglés | MEDLINE | ID: mdl-27828149

RESUMEN

A new instrument for fast measurement of frequency response of high-bandwidth optical and electronic devices is reported. Single-shot frequency spectrum measurements are enabled by time-stretch technology. An extremely fast measurement time of 27 ns is reported for the instrument. The reported instrument enables single-shot impulse response measurements with a 40 GHz bandwidth, which could be extended to beyond 100 GHz by using a faster electro-optic modulator. An ultra-low jitter of 20.5 fs is reported for the proposed instrument. The impulse responses measured using this technique are shown to correspond consistently with the manufacturer's specifications for the device under test. The reported instrument makes possible high-speed network parameter measurements, thereby enabling high-speed production-level testing of high-bandwidth opto-electronic devices/circuits/subsystems/systems and complex permittivity measurement of dielectric materials at a much reduced test time, lowering the test costs in a production environment.

9.
Proc Natl Acad Sci U S A ; 109(29): 11630-5, 2012 Jul 17.
Artículo en Inglés | MEDLINE | ID: mdl-22753513

RESUMEN

Optical microscopy is one of the most widely used diagnostic methods in scientific, industrial, and biomedical applications. However, while useful for detailed examination of a small number (< 10,000) of microscopic entities, conventional optical microscopy is incapable of statistically relevant screening of large populations (> 100,000,000) with high precision due to its low throughput and limited digital memory size. We present an automated flow-through single-particle optical microscope that overcomes this limitation by performing sensitive blur-free image acquisition and nonstop real-time image-recording and classification of microparticles during high-speed flow. This is made possible by integrating ultrafast optical imaging technology, self-focusing microfluidic technology, optoelectronic communication technology, and information technology. To show the system's utility, we demonstrate high-throughput image-based screening of budding yeast and rare breast cancer cells in blood with an unprecedented throughput of 100,000 particles/s and a record false positive rate of one in a million.


Asunto(s)
Diagnóstico por Imagen/métodos , Citometría de Flujo/métodos , Ensayos Analíticos de Alto Rendimiento/métodos , Técnicas Analíticas Microfluídicas/métodos , Microscopía por Video/métodos , Línea Celular Tumoral , Femenino , Humanos , Saccharomycetales
10.
Appl Opt ; 53(3): 376-82, 2014 Jan 20.
Artículo en Inglés | MEDLINE | ID: mdl-24514122

RESUMEN

Minimally invasive surgery procedures benefit from a reduced size of endoscopic devices. A prospective path to implement miniaturized endoscopy is single optical-fiber-based spectrally encoded imaging. While simultaneous spectrally encoded inertial-scan-free imaging and laser microsurgery have been successfully demonstrated in a large table setup, a highly miniaturized optical design would promote the development of multipurpose endoscope heads. This paper presents a highly scalable, entirely transmissive axial design for a spectral 2D spatial disperser. The proposed design employs a grating prism and a virtual imaged phased array (VIPA). Based on semi-analytical device modeling, we performed a systematic parameter analysis to assess the spectral disperser's manufacturability and to obtain an optimum application-specific design. We found that, in particular, a low grating period combined with a high optical input bandwidth and low VIPA tilt showed favorable results in terms of a high spatial resolution, a small device diameter, and a large field of view. Our calculations reveal that a reasonable imaging performance can be achieved with system diameters of below 5 mm, which renders the proposed 2D spatial disperser design highly suitable for use in future endoscope heads that combine mechanical-scan-free imaging and laser microsurgery.


Asunto(s)
Endoscopios , Terapia por Láser/instrumentación , Lentes , Iluminación/instrumentación , Microcirugia/instrumentación , Refractometría/instrumentación , Cirugía Asistida por Computador/instrumentación , Diseño de Equipo , Análisis de Falla de Equipo , Aumento de la Imagen/instrumentación , Luz , Miniaturización , Dispersión de Radiación , Integración de Sistemas
11.
Opt Express ; 21(18): 21618-27, 2013 Sep 09.
Artículo en Inglés | MEDLINE | ID: mdl-24104036

RESUMEN

Time stretch transformation of wideband waveforms boosts the performance of analog-to-digital converters and digital signal processors by slowing down analog electrical signals before digitization. The transform is based on dispersive Fourier transformation implemented in the optical domain. A coherent receiver would be ideal for capturing the time-stretched optical signal. Coherent receivers offer improved sensitivity, allow for digital cancellation of dispersion-induced impairments and optical nonlinearities, and enable decoding of phase-modulated optical data formats. Because time-stretch uses a chirped broadband (>1 THz) optical carrier, a new coherent detection technique is required. In this paper, we introduce and demonstrate coherent time stretch transformation; a technique that combines dispersive Fourier transform with optically broadband coherent detection.

12.
Opt Express ; 21(23): 28960-7, 2013 Nov 18.
Artículo en Inglés | MEDLINE | ID: mdl-24514410

RESUMEN

The angular light scattering profile of microscopic particles significantly depends on their morphological parameters, such as size and shape. This dependency is widely used in state-of-the-art flow cytometry methods for particle classification. We introduce a new spectrally encoded angular light scattering method, with potential application in scanning flow cytometry. We show that a one-to-one wavelength-to-angle mapping enables the measurement of the angular dependence of scattered light from microscopic particles over a wide dynamic range. Improvement in dynamic range is obtained by equalizing the angular dependence of scattering via wavelength equalization. Continuous angular spectrum is obtained without mechanical scanning enabling single-shot measurement. Using this information, particle morphology can be determined with improved accuracy. We derive and experimentally verify an analytic wavelength-to-angle mapping model, facilitating rapid data processing. As a proof of concept, we demonstrate the method's capability of distinguishing differently sized polystyrene beads. The combination of this technique with time-stretch dispersive Fourier transform offers real-time and high-throughput (high frame rate) measurements and renders the method suitable for integration in standard flow cytometers.

13.
Opt Lett ; 38(4): 446-8, 2013 Feb 15.
Artículo en Inglés | MEDLINE | ID: mdl-23455097

RESUMEN

We present a digital postprocessing linearization technique to efficiently suppress dynamic distortions added to a wideband signal in an analog optical link. Our technique achieves up to 35 dB suppression of intermodulation distortions over multiple octaves of signal bandwidth. In contrast to conventional linearization methods, it does not require excessive analog bandwidth for performing digital correction. This is made possible by regenerating undesired distortions from the captured output, and subtracting it from the distorted digitized signal. Moreover, we experimentally demonstrate a record spurious-free dynamic range of 120 dB·Hz(2/3) over a 6 GHz electrical signal bandwidth. While our digital broadband linearization technique advances state-of-the-art optical links, it can also be applied to other nonlinear dynamic systems.


Asunto(s)
Dispositivos Ópticos , Ondas de Radio , Artefactos , Modelos Lineales
14.
J Opt Soc Am A Opt Image Sci Vis ; 30(10): 2124-32, 2013 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-24322867

RESUMEN

Optical sensing and imaging methods for biomedical applications, such as spectroscopy and laser-scanning fluorescence microscopy, are incapable of performing sensitive detection at high scan rates due to the fundamental trade-off between sensitivity and speed. This is because fewer photons are detected during short integration times and hence the signal falls below the detector noise. Optical postamplification can, however, overcome this challenge by amplifying the collected optical signal after collection and before photodetection. Here we present a theoretical analysis of the sensitivity of high-speed biomedical sensing and imaging systems enhanced by optical postamplifiers. As a case study, we focus on Raman amplifiers because they produce gain at any wavelength within the gain medium's transparency window and are hence suitable for biomedical applications. Our analytical model shows that when limited by detector noise, such optically postamplified systems can achieve a sensitivity improvement of up to 20 dB in the visible to near-infrared spectral range without sacrificing speed. This analysis is expected to be valuable for design of fast real-time biomedical sensing and imaging systems.


Asunto(s)
Técnicas Biosensibles , Diagnóstico por Imagen/métodos , Algoritmos , Amplificadores Electrónicos , Procesamiento de Imagen Asistido por Computador , Rayos Láser , Luz , Microscopía Fluorescente/métodos , Óptica y Fotónica , Procesamiento de Señales Asistido por Computador , Espectrofotometría/métodos , Espectrometría Raman
15.
Appl Opt ; 52(27): 6735-43, 2013 Sep 20.
Artículo en Inglés | MEDLINE | ID: mdl-24085172

RESUMEN

A general method for compressing the modulation time-bandwidth product of analog signals is introduced. As one of its applications, this physics-based signal grooming, performed in the analog domain, allows a conventional digitizer to sample and digitize the analog signal with variable resolution. The net result is that frequency components that were beyond the digitizer bandwidth can now be captured and, at the same time, the total digital data size is reduced. This compression is lossless and is achieved through a feature selective reshaping of the signal's complex field, performed in the analog domain prior to sampling. Our method is inspired by operation of Fovea centralis in the human eye and by anamorphic transformation in visual arts. The proposed transform can also be performed in the digital domain as a data compression algorithm to alleviate the storage and transmission bottlenecks associated with "big data."


Asunto(s)
Algoritmos , Biomimética/métodos , Compresión de Datos/métodos , Fóvea Central/fisiología , Interpretación de Imagen Asistida por Computador/métodos , Modelos Biológicos , Percepción Visual/fisiología , Simulación por Computador , Humanos
16.
Appl Opt ; 52(17): 4072-6, 2013 Jun 10.
Artículo en Inglés | MEDLINE | ID: mdl-23759858

RESUMEN

We report an ultrafast web inspector that operates at a 1000 times higher scan rate than conventional methods. This system is based on a hybrid dispersion laser scanner that performs line scans at nearly 100 MHz. Specifically, we demonstrate web inspection with detectable resolution of 48.6 µm/pixel (scan direction) × 23 µm (web flow direction) within a width of view of 6 mm at a record high scan rate of 90.9 MHz. We demonstrate the identification and evaluation of particles on silicon wafers. This method holds great promise for speeding up quality control and hence reducing manufacturing costs.


Asunto(s)
Aumento de la Imagen/instrumentación , Industrias/instrumentación , Rayos Láser , Ensayo de Materiales/instrumentación , Microscopía Confocal/instrumentación , Fotometría/instrumentación , Refractometría/instrumentación , Diseño de Equipo , Análisis de Falla de Equipo , Propiedades de Superficie
17.
Nat Commun ; 14(1): 6065, 2023 Sep 28.
Artículo en Inglés | MEDLINE | ID: mdl-37770444

RESUMEN

Bandwidth and noise are fundamental considerations in all communication and signal processing systems. The group-velocity dispersion of optical fibers creates nulls in their frequency response, limiting the bandwidth and hence the temporal response of communication and signal processing systems. Intensity noise is often the dominant optical noise source for semiconductor lasers in data communication. In this paper, we propose and demonstrate a class of electrooptic modulators that is capable of mitigating both of these problems. The modulator, fabricated in thin-film lithium niobate, simultaneously achieves phase diversity and differential operations. The former compensates for the fiber's dispersion penalty, while the latter overcomes intensity noise and other common mode fluctuations. Applications of the so-called four-phase electrooptic modulator in time-stretch data acquisition and in optical communication are demonstrated.

18.
Opt Express ; 20(18): 19612-7, 2012 Aug 27.
Artículo en Inglés | MEDLINE | ID: mdl-23037013

RESUMEN

We report high-throughput optical coherence tomography (OCT) that offers 1,000 times higher axial scan rate than conventional OCT in the 800 nm spectral range. This is made possible by employing photonic time-stretch for chirping a pulse train and transforming it into a passive swept source. We demonstrate a record high axial scan rate of 90.9 MHz. To show the utility of our method, we also demonstrate real-time observation of laser ablation dynamics. Our high-throughput OCT is expected to be useful for industrial applications where the speed of conventional OCT falls short.


Asunto(s)
Algoritmos , Aumento de la Imagen/instrumentación , Interpretación de Imagen Asistida por Computador/instrumentación , Tomografía de Coherencia Óptica/instrumentación , Diseño Asistido por Computadora , Diseño de Equipo , Análisis de Falla de Equipo , Reproducibilidad de los Resultados , Sensibilidad y Especificidad
19.
Opt Express ; 20(13): 14109-16, 2012 Jun 18.
Artículo en Inglés | MEDLINE | ID: mdl-22714475

RESUMEN

High-throughput real-time optical integrators are of great importance for applications that require ultrafast optical information processing, such as real-time phase reconstruction of ultrashort optical pulses. In many of these applications, integration of wide optical bandwidth signals is required. Unfortunately, conventional all-optical integrators based on passive devices are usually sensitive to the wavelength and bandwidth of the optical carrier. Here, we propose and demonstrate a passive all-optical intensity integrator whose operation is independent of the optical signal wavelength and bandwidth. The integrator is implemented based on modal dispersion in a multimode waveguide. By controlling the launch conditions of the input beam, the device produces a rectangular temporal impulse response. Consequently, a temporal intensity integration of an arbitrary optical waveform input is performed within the rectangular time window. The key advantage of this device is that the integration operation can be performed independent of the input signal wavelength and optical carrier bandwidth. This is preferred in many applications where optical signals of different wavelengths are involved. Moreover, thanks to the use of a relatively short length of multimode waveguide, lower system latency is achieved compared to the systems using long dispersive fibers. To illustrate the versatility of the optical integrator, we demonstrate temporal intensity integration of optical waveforms with different wavelengths and optical carrier bandwidths. Finally, we use this device to perform high-throughput, single-shot, real-time optical phase reconstruction of phase-modulated signals at telecommunications bit rates.


Asunto(s)
Dispositivos Ópticos , Procesamiento de Señales Asistido por Computador/instrumentación , Telecomunicaciones/instrumentación , Sistemas de Computación , Diseño Asistido por Computadora , Diseño de Equipo , Análisis de Falla de Equipo
20.
Light Sci Appl ; 11(1): 14, 2022 Jan 10.
Artículo en Inglés | MEDLINE | ID: mdl-35013092

RESUMEN

Recording electric field evolution in single-shot with THz bandwidth is needed in science including spectroscopy, plasmas, biology, chemistry, Free-Electron Lasers, accelerators, and material inspection. However, the potential application range depends on the possibility to achieve sub-picosecond resolution over a long time window, which is a largely open problem for single-shot techniques. To solve this problem, we present a new conceptual approach for the so-called spectral decoding technique, where a chirped laser pulse interacts with a THz signal in a Pockels crystal, and is analyzed using a grating optical spectrum analyzer. By borrowing mathematical concepts from photonic time stretch theory and radio-frequency communication, we deduce a novel dual-output electro-optic sampling system, for which the input THz signal can be numerically retrieved-with unprecedented resolution-using the so-called phase diversity technique. We show numerically and experimentally that this approach enables the recording of THz waveforms in single-shot over much longer durations and/or higher bandwidth than previous spectral decoding techniques. We present and test the proposed DEOS (Diversity Electro-Optic Sampling) design for recording 1.5 THz bandwidth THz pulses, over 20 ps duration, in single-shot. Then we demonstrate the potential of DEOS in accelerator physics by recording, in two successive shots, the shape of 200 fs RMS relativistic electron bunches at European X-FEL, over 10 ps recording windows. The designs presented here can be used directly for accelerator diagnostics, characterization of THz sources, and single-shot Time-Domain Spectroscopy.

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