Conflicts between priming and episodic retrieval: a question of fluency?

Human memory consists of different underlying processes whose interaction can result in counterintuitive findings. One phenomenon that relies on various types of mnemonic processes is the repetition priming effect for unfamiliar target faces in familiarity decisions, which is highly variable and may even reverse. Here, we tested the hypothesis that this reversed priming effect may be due to a conflict between target fluency signals and episodic retrieval processes. After replicating the reverse priming effect, three different manipulations were effective in diminishing it. We suggest that each of these manipulations diminished the ambiguity regarding the source of priming-induced fluency of target processing. Our findings argue against a strictly independent view of different types of memory.

Computational models of the "active self" and its disturbances in schizophrenia.

The notion that self-disorders are at the root of the emergence of schizophrenia rather than a symptom of the disease, is getting more traction in the cognitive sciences. This is in line with philosophical approaches that consider an enactive self, constituted through action and interaction with the environment. We thereby analyze different definitions of the self and evaluate various computational theories lending to these ideas. Bayesian and predictive processing are promising approaches for computational modeling of the "active self". We evaluate their implementation and challenges in computational psychiatry and cognitive developmental robotics. We describe how and why embodied robotic systems provide a valuable tool in psychiatry to assess, validate, and simulate mechanisms of self-disorders. Specifically, mechanisms involving sensorimotor learning, prediction, and self-other distinction, can be assessed with artificial agents. This link can provide essential insights to the formation of the self and new avenues in the treatment of psychiatric disorders.

Neurocognitive mechanisms of individual differences in face cognition: a replication and extension.

Face cognition performance is related to individual differences in cognitive subprocesses, as reflected in the amplitudes and latencies of event-related brain potentials (ERPs; Herzmann, Kunina, Sommer, & Wilhelm, 2010). In order to replicate and extend these findings, 110 participants were tested on a comprehensive task battery measuring face cognition abilities and established cognitive abilities, followed by ERP recordings in a face-learning-and-recognition task. We replicated the links of the ERP components indicating the speed of structural face encoding (N170 latency) and access to structural representations in memory (early repetition effect [ERE]/N250r) with the accuracy and speed of face cognition and with established cognitive abilities. As a novel result, we differentiated between the accuracy of face perception and face memory on the behavioral and electrophysiological levels and report a relationship between basic visual processes (P100 amplitude) and face memory. Moreover, the brain-behavior relationships for the ERE/N250r held true, even though we eliminated pictorial and perceptual structural codes from the priming effects by using backward masking of the primes with novel unfamiliar faces. On a methodological level, we demonstrated the utility of the latent difference score modeling technique to parameterize ERP difference components (e.g., ERE/N250r) on a latent level and link them to face cognition abilities.

Brain mechanisms underlying the modulation of heart rate variability when accepting and reappraising emotions.

Heart rate variability (HRV) has been linked to resilience and emotion regulation (ER). How HRV and brain processing interact during ER, however, has remained elusive. Sixty-two subjects completed the acquisition of resting HRV and task HRV while performing an ER functional Magnetic Resonance Imaging (fMRI) paradigm, which included the differential strategies of ER reappraisal and acceptance in the context of viewing aversive pictures. We found high correlations of resting and task HRV across all emotion regulation strategies. Furthermore, individuals with high levels of resting, but not task, HRV showed numerically lower distress during ER with acceptance. Whole-brain fMRI parametrical modulation analyses revealed that higher task HRV covaried with dorso-medial prefrontal activation for reappraisal, and dorso-medial prefrontal, anterior cingulate and temporo-parietal junction activation for acceptance. Subjects with high resting HRV, compared to subjects with low resting HRV, showed higher activation in the pre-supplementary motor area during ER using a region of interest approach. This study demonstrates that while resting and task HRV exhibit a positive correlation, resting HRV seems to be a better predictor of ER capacity. Resting and task HRV were associated with ER brain activation in mid-line frontal cortex (i.e. DMPFC).

A Lower-Class Advantage in Face Memory.

People remember what they deem important. In line with research suggesting that lower-class (vs. higher class) individuals spontaneously appraise other people as more relevant, we show that social class is associated with the habitual use of face memory. We find that lower-class (vs. higher class) participants exhibit better incidental memory for faces (i.e., spontaneous memory for faces they had not been instructed to memorize; Studies 1 and 2). No social-class differences emerge for faces participants are instructed to learn (Study 2), suggesting that this pattern reflects class-based relevance appraisals rather than memory ability. Study 3 extends our findings to eyewitness identification. Lower-class (vs. higher-class) participants' eyewitness accuracy is less impacted by the explicit relevance of a target (clearly relevant thief vs. incidental bystander). Integrative data analysis shows a robust negative association between social class and spontaneous face memory. Preregistration (Studies 1 and 3) and cross-cultural replication (Study 2) further strengthen the results.

#EEGManyLabs: Investigating the replicability of influential EEG experiments.

There is growing awareness across the neuroscience community that the replicability of findings about the relationship between brain activity and cognitive phenomena can be improved by conducting studies with high statistical power that adhere to well-defined and standardised analysis pipelines. Inspired by recent efforts from the psychological sciences, and with the desire to examine some of the foundational findings using electroencephalography (EEG), we have launched #EEGManyLabs, a large-scale international collaborative replication effort. Since its discovery in the early 20th century, EEG has had a profound influence on our understanding of human cognition, but there is limited evidence on the replicability of some of the most highly cited discoveries. After a systematic search and selection process, we have identified 27 of the most influential and continually cited studies in the field. We plan to directly test the replicability of key findings from 20 of these studies in teams of at least three independent laboratories. The design and protocol of each replication effort will be submitted as a Registered Report and peer-reviewed prior to data collection. Prediction markets, open to all EEG researchers, will be used as a forecasting tool to examine which findings the community expects to replicate. This project will update our confidence in some of the most influential EEG findings and generate a large open access database that can be used to inform future research practices. Finally, through this international effort, we hope to create a cultural shift towards inclusive, high-powered multi-laboratory collaborations.

Sharing the filmic experience - The physiology of socio-emotional processes in the cinema.

As we identify with characters on screen, we simulate their emotions and thoughts. This is accompanied by physiological changes such as galvanic skin response (GSR), an indicator for emotional arousal, and respiratory sinus arrhythmia (RSA), referring to vagal activity. We investigated whether the presence of a cinema audience affects these psychophysiological processes. The study was conducted in a real cinema in Berlin. Participants came twice to watch previously rated emotional film scenes eliciting amusement, anger, tenderness or fear. Once they watched the scenes alone, once in a group. We tested whether the vagal modulation in response to the mere presence of others influences explicit (reported) and implicit markers (RSA, heart rate (HR) and GSR) of emotional processes in function of solitary or collective enjoyment of movie scenes. On the physiological level, we found a mediating effect of vagal flexibility to the mere presence of others. Individuals showing a high baseline difference (alone vs. social) prior to the presentation of film, maintained higher RSA in the alone compared to the social condition. The opposite pattern emerged for low baseline difference individuals. Emotional arousal as reflected in GSR was significantly more pronounced during scenes eliciting anger independent of the social condition. On the behavioural level, we found evidence for emotion-specific effects on reported empathy, emotional intensity and Theory of Mind. Furthermore, people who decrease their RSA in response to others' company are those who felt themselves more empathically engaged with the characters. Our data speaks in favour of a specific role of vagal regulation in response to the mere presence of others in terms of explicit empathic engagement with characters during shared filmic experience.

Corrigendum: No Robust Association between Static Markers of Testosterone and Facets of Socio-Economic Decision Making.

[This corrects the article on p. 250 in vol. 11, PMID: 29326567.].

No Robust Association between Static Markers of Testosterone and Facets of Socio-Economic Decision Making.

Digit ratio (2D:4D) and facial width-to-height ratio (WHR) are supposedly static indicators of testosterone exposition during prenatal and pubertal lifetime, respectively. Both measures have been linked to aggressive and assertive behavior in laboratory economic games, as well as in real world scenarios. Most of the research-often limited to male subjects-considers the associations between these behaviors, traits, and hormonal markers separately for 2D:4D and WHR. Reported associations are weak and volatile. In the present study we had independent raters assess 2D:4D and WHR in a sample of N = 175 participants who played the ultimatum game (UG). Respondent behavior in UG captures the tendency to reject unfair offers (negative reciprocity). If unfair UG offers are seen as provocations, then individuals with stronger testosterone exposition may be more prone to reject such offers. Economists argue that negative reciprocity reflects altruistic punishment, since the rejecting individual is sacrificing own resources. However, recent studies suggest that self-interest, in terms of status defense plays a substantial role in decisions to reject unfair offers. We also assessed social preferences by social value orientation and assertiveness via self-report. By applying structural equation modeling we estimated the latent level association of 2D:4D and WHR with negative reciprocity, assertiveness and prosociality in both sexes. Results revealed no robust association between any of the trait measures and hormonal markers. The measures of 2D:4D and WHR were not related with each other. Multigroup models based on sex suggested invariance of factor loadings allowing to compare hormone-behavior relationships of females and males. Only when collapsing across sex greater WHR was weakly associated with assertiveness, suggesting that individuals with wider faces tend to express greater status defense. Only the right hand 2D:4D was weakly associated with prosocial behavior, indicating that individuals with lower prenatal testosterone exposure are more cooperative. Rejection behavior in UG was not related with 2D:4D nor WHR in any of the models. There were also no curvilinear associations between 2D:4D and prosociality as theorized in the literature. Our results suggest that previous studies over-estimated the role of static markers of testosterone in accounting for aggression and competition behavior in males.

Behavioral and neuronal determinants of negative reciprocity in the ultimatum game.

The rejection of unfair offers in the ultimatum game (UG) indicates negative reciprocity. The model of strong reciprocity claims that negative reciprocity reflects prosociality because the rejecting individual is sacrificing resources in order to punish unfair behavior. However, a recent study found that the rejection rate of unfair offers is linked to assertiveness (status defense model). To pursue the question what drives negative reciprocity, the present study investigated individual differences in the rejection of unfair offers along with their behavioral and neuronal determinants. We measured fairness preferences and event-related potentials (ERP) in 200 healthy participants playing a computerized version of the UG with pictures of unfair and fair proposers. Structural equation modeling (SEM) on the behavioral data corroborated both the strong reciprocity and the status defense models of human cooperation: Not only more prosocial but also more assertive individuals were more likely to show negative reciprocity by rejecting unfair offers. Experimental ERP results confirmed the feedback negativity (FN) as a neural signature of fairness processing. Multilevel SEM of brain-behavior relationships revealed that negative reciprocity was significantly associated with individual differences in FN amplitudes in response to proposers. Our results confirm stable individual differences in fairness processing at the behavioral and neuronal level.

Independence of valence and reward in emotional word processing: electrophysiological evidence.

BOTH EMOTION AND REWARD ARE PRIMARY MODULATORS OF COGNITION: emotional word content enhances word processing, and reward expectancy similarly amplifies cognitive processing from the perceptual up to the executive control level. Here, we investigate how these primary regulators of cognition interact. We studied how the anticipation of gain or loss modulates the neural time course (event-related potentials, ERPs) related to processing of emotional words. Participants performed a semantic categorization task on emotional and neutral words, which were preceded by a cue indicating that performance could lead to monetary gain or loss. Emotion-related and reward-related effects occurred in different time windows, did not interact statistically, and showed different topographies. This speaks for an independence of reward expectancy and the processing of emotional word content. Therefore, privileged processing given to emotionally valenced words seems immune to short-term modulation of reward. Models of language comprehension should be able to incorporate effects of reward and emotion on language processing, and the current study argues for an architecture in which reward and emotion do not share a common neurobiological mechanism.