Biomechanical evaluation of suture-tendon interface and tissue holding of three suture configurations in torn and degenerated versus intact human rotator cuffs.

PURPOSE: The purpose of this study was to biomechanically evaluate suture-tendon interface and tissue holding of three sutures in torn and degenerated versus intact human rotator cuffs. METHODS: Sixty-three human rotator cuff tendons were divided into torn degenerated group (TDG), n = 21 and intact group (IG), n = 42. Ultimate tension load (UTL) and cyclic loading were tested for three arthroscopic sutures: simple, horizontal, and massive cuff sutures (MCS). RESULTS: Ultimate tension load was significantly higher (p < 0.05) for the MCS (194 ± 68 N) in comparison with the simple (105 ± 48 N) and horizontal sutures (141 ± 49 N) in IG. In TDG, UTL was not significantly higher (n.s.) for MCS (118 ± 49 N), simple (79 ± 30 N), and horizontal sutures (107 ± 28 N) in comparison with IG. MCS (118 ± 49 N) showed no significantly superior UTL in comparison with the simple and horizontal sutures in the TDG. MCA elongation was 0.6 ± 0.7 mm in the IG and 1.3 ± 0.7 mm in the TDG, while horizontal suture elongation was 0.7 ± 0.4 mm in the IG and 1.3 ± 0.5 mm in the TDG. Simple suture elongation was 1.1 ± 0.5 mm in the IG and 1.6 ± 0.7 mm in the TDG. CONCLUSION: Human torn and degenerated rotator cuffs have poor tissue quality, significantly lower UTL and higher cyclic elongation in comparison with intact cuffs regardless of the type of suture used for repair, which invites the need for repair techniques that grasps greater tissue volume in addition to augmentation techniques. CLINICAL RELEVANCE: Clinicians better use repair techniques that grasp greater tissue volume (e.g. MCS, modified Mason-Allen cross bridge, double-row cross bridge, etc.) when repairing the torn and degenerated rotator cuffs.

Resection arthroplasty with and without capsular interposition for treatment of severe hallux rigidus.

Resection arthroplasty-known as the Keller procedure-is used for the treatment of severe hallux rigidus. As a modification of this procedure, resection arthroplasty is combined with cheilectomy and interposition of the dorsal capsule and extensor hallucis brevis tendon, which are then sutured to the flexor hallucis brevis tendon on the plantar side of the joint (capsular interposition arthroplasty). In this study the clinical and radiological outcome of 22 feet treated by interposition arthroplasty were investigated and compared with those of 30 feet on which the Keller procedure was performed. The mean follow-up period was 15 months. No statistically significant difference was found between either group concerning patient satisfaction, clinical outcome and increase in range of motion of the first metatarsophalangeal joint. At follow-up, patients who had undergone interposition arthroplasty did not show statistically significantly better American Orthopaedic Foot and Ankle Society (AOFAS) forefoot scores than those of the Keller procedure group. A high rate of osteonecrosis of the first metatarsal head was found in both groups. These radiological findings did not correlate with the clinical outcome at follow-up. In conclusion, no significant benefit in clinical or radiological outcome was found for capsular interposition arthroplasty compared with the Keller procedure.

Tapping test in patients with painful bone marrow edema of the knee.

BACKGROUND: Although bone marrow edema (BME) of the knee is a common phenomenon, physical tests to diagnose this condition have not been investigated. We hypothesized that a mallet test would be useful as a diagnostic aid and a screening tool. METHODS: Seventy patients (36 female, 34 male) were investigated in this controlled study. Group 1 consisted of patients with painful BME in the knee and group 2 of patients with a painful knee without BME. Pain provoked by a reflex mallet was assessed for each quadrant on a visual analog scale (VAS). RESULTS: The VAS score was 3.7 (+/-2.1 cm) for quadrants affected by BME (group 1), 1.59 (+/-1.44) in nonaffected quadrants of the knee affected by BME (group 1) and, 0.85 (+/-0.85) in painful knees without BME (group 2). Pain on the tapping test was significantly correlated with the presence of BME in the affected knee (P<0.0001) and the affected quadrant (P<0.0001 for the medial femoral condyle and the medial femoral plateau). A threshold value of VAS 2.0 for a tapping test to be positive in the distinction of BME affected quadrants of group 1 and all quadrants of group 2 sensitivity was 90.4%, specificity 83.7%, positive predictive value 73.4%, and negative predictive value 94.6% was determined. CONCLUSION: The tapping test is a good screening instrument to diagnose BME in the knee.

Natural course of intra-articular shifting bone marrow edema syndrome of the knee.

BACKGROUND: Intra-articular shift (migration) of bone marrow edema syndrome (BMES) is a very rare disease. Only a few cases have been reported thus far. The condition may cause the clinician to suspect an aggressive disease. METHODS: We reviewed eight patients (four women and four men) with unilateral BMES located in the knee. The patients were aged 39 to 56 years (mean, 49.2 years). In all patients, bone marrow edema (BME) initially observed on magnetic resonance imaging (MR imaging) shifted within the same joint, i.e. from the medial to the lateral femoral condyle or the adjacent bone. Seven patients were given conservative therapy, including limited weight-bearing, for a period of three weeks after the initial detection of BMES, whereas one patient underwent surgical core decompression twice. RESULTS: MR imaging showed complete restitution in 6 cases and a small residual edema in one case. A final control MR could not be obtained for one patient, who had no pain. A further patient had an avascular necrosis of the contralateral hip after 16 months. Improvement on MR imaging was correlated with the clinical outcome in all cases. All patients became asymptomatic after a mean period of 9 months (6-11). INTERPRETATION: Intra-articular shifting BMES is a very rare condition. As the disease is self-limiting, conservative therapy may be recommended.

MRI-demonstrated outcome of subchondral stress fractures of the knee after treatment with iloprost or tramadol: observations in 14 patients.

OBJECTIVE: To investigate the outcome of subchondral stress fractures (SSF) of the knee after treatment with the prostacyclin analogue Iloprost or the opioid analgesic Tramadol. DESIGN: Case series/retrospective review. SETTING: Tertiary care center. PATIENTS: Fourteen patients with at least a single subchondral stress fracture of the knee, surrounded by bone marrow edema, visible on T1-weighted and short tau inversion recovery magnetic resonance images. INTERVENTIONS: Nine patients had been treated with oral Iloprost (group 1; 11 SSF) and 5 patients with Tramadol (group 2; 5 SSF) for 4 weeks in the course of a double-blind, randomized clinical trial. MR images were obtained at baseline (1 day before the start of treatment), after 3 months, and after 1 year. MAIN OUTCOME VARIABLES: SSF volumes and their rates of change between baseline and follow-up examinations, as determined on T1-weighted images by computer-assisted quantification. RESULTS: After three months, the SSF volumes had decreased by a median of 42.2% in group 1 and increased by a median of 2.2% in group 2 (P = 0.008). After 1 year, the median decrease in SSF volumes was 100.0% in group 1 and 65.7% in group 2 (P = 0.017). CONCLUSION: This small case series suggests that healing of SSF is more pronounced after Iloprost treatment.

The "cruciate suture" for arthroscopic meniscal repair: a new technique.

Meniscal repair has become the treatment of choice whenever a reparable tear is diagnosed. Fixation strength of the repair technique is always of paramount importance in comparison of various techniques, especially after the evolution of many arthroscopic all-inside devices. We present a new arthroscopic meniscal repair suturing technique called "cruciate suture." One 18-gauge needle and suture material are used. The needle is loaded with the suture material from its tip. The suture is folded at the tip of the needle, which is inserted to penetrate the skin obliquely to appear inside the joint, making a loop. The needle is retracted, while the suture is kept inside of it. The needle is reinserted at the same hole, appearing inside the joint and making a second loop. The needle is retracted completely. With the use of a probe, the loop at the second point is pulled through the loop at the first point, thereby forming a free end. The 2 limbs of the loop are pulled, thus driving the limb with the free end outside of the joint. The first oblique vertical suture is completed at this point. The needle is reloaded by the suture limb from the first point. The previous procedure is repeated, with use of the second skin hole and the third and fourth points to make the second oblique vertical suture. The cruciate suture is now complete. We tested the ultimate tension load (UTL) of the cruciate suture in comparison with that of the vertical suture (the gold standard). A total of 36 tests (18 for the cruciate suture and 18 for the vertical suture) were performed on human menisci. The mean UTL of the cruciate suture was measured at 110 N; the mean UTL of the vertical suture was 67 N.

A new arthroscopic technique for revision of the posterior compartment in symptomatic total knee arthroplasty.

Arthroscopy is effective in treating the symptomatic knee following total knee arthroplasty. A small number of patients complain about postoperative pain in the posterior compartment. Loose bodies and degenerated remnants of the menisci are the main reasons for this pain. We present a new technique for diagnostic and therapeutic arthroscopy of the posterior compartments in patients with symptomatic total knee arthroplasty. After standard anterior arthroscopy, a wide circular notchplasty is performed to allow easy access to the posterior lateral compartment of the knee joint and to apply a posterolateral working portal under direct arthroscopic control. If inspection of the posteromedial compartment is necessary, the loose tissue behind the posterior cruciate ligament is resected to gain access to the posteromedial compartment.

Bone marrow edema syndrome of the femoral head: treatment with the prostacyclin analogue iloprost vs. core decompression: an MRI-controlled study.

BACKGROUND: The purpose of this study was to assess the efficacy of the vasoactive drug iloprost in Bone Marrow Edema Syndrome (BMES) and to compare it to the results of a control group treated by core decompression. PATIENTS AND METHODS: 38 hips (36 patients) with BMES in the femoral head were investigated. In group A, 18 hips (17 patients; mean age 49 years) were treated with iloprost, a vasoactive drug that dilates arterioles and venules, reduces capillary permeability and suppresses platelet aggregation. The therapy comprised a series of five infusions with 20 microg iloprost over 6 hours on 5 consecutive days. Weight bearing was reduced for up to 3 weeks, depending on the severity of symptoms. In group B, 20 hips (19 patients; mean age 41 years) underwent surgical core decompression of the femoral head followed by 6 weeks of partial weight bearing. Both groups were evaluated clinically, radiographically and by MRI. RESULTS: In group A, one patient had to discontinue therapy on the first day because of severe headache. In the remaining patients the Harris Hip Score (HHS) improved from a mean of 64.7 points (range 44-89) before therapy to 97.0 points (83-100) after 3 months. MRI controls showed complete remission in all hips. In group B, the preoperative HHS improved from 53.7 points (31-82) to 95.1 points (39-100) after 3 months. MRI controls showed complete remission of BMES in 14 hips, residual focal bone marrow edema in four hips and a small osteonecrotic area in two hips. In both groups the high level of clinical recovery was maintained at the last examination after a mean follow up of 11 months in group A and 12 months in group B. CONCLUSION: The parenteral application of iloprost can achieve equal or better results in the treatment of bone marrow edema syndrome of the hip compared to core decompression.

MRI-controlled analysis of 104 patients with painful bone marrow edema in different joint localizations treated with the prostacyclin analogue iloprost.

BACKGROUND: Bone marrow edema (BME) is a common cause of pain of the musculoskeletal system. The aim of the study was to assess the efficacy of iloprost in the treatment of BME of different localizations and etiologies. PATIENTS AND METHODS: We reviewed 104 patients (54 male, 50 female) with BME. Their mean age was 52.8 +/- 14.7 years. BME was located 50 times in the knee, 19 times in the talus, 18 times in the femoral head and 17 times in other bones. Patients were allocated to three distinct etiological groups: 27 cases were estimated to have idiopathic BME, 16 post-traumatic BME and the other 61 BME secondary to activated osteoarthritis or mechanical stress. Therapy consisted of a series of five iloprost infusions with either 20, 25 or 50 microg of iloprost given over 6 hours on 5 consecutive days each. RESULTS: At the clinical follow-up four months after therapy, the pain level of the 104 patients at rest had diminished by a mean of 73% (p<0.0001): 64% of patients reported a reduction, 34% no change and 2% an increase in pain at rest. Pain under stress decreased by a mean of 59%, (p<0.0001): 76% of patients had less pain during activity, 22% no change from baseline and 2% an increased pain level. On MRI, 65% had significant reduction of BME size or complete normalization and 20% showed no change. Worsening of the MRI pattern was found in 2%. 13% were lost to MRI follow-up. Side effects were significantly reduced by lowering the daily dose from 50 to 20 microg, without impairment of therapeutic effect. CONCLUSION: The authors conclude that the use of parenteral iloprost might be a viable method in the treatment of BME of different etiologies.

A new soft transglenoidal suture anchor for arthroscopic labrum fixation.

Inherent in most transglenoidal suture stabilization techniques of unstable shoulders is the unreliable fixation of posterior knots on the fascia. The transglenoidal suture anchor (TSA) technique overcomes this disadvantage. The TSA is a 1.5-cm loop of a No. 3 braided polyester thread with 5 knots. The loop is loaded with 1 or 2 sutures. Using a transglenoidal shuttle suture, it is pulled into a transglenoidal drill hole from the back in a retrograde fashion. The anchor is stopped at the posterior cortex of the glenoid by the knot. Using an arthroscopic suture passer technique (Bird Beak; Arthrex, Naples, FL) sutures are applied in the anterior-inferior part of the capsule, tied with a self-locking sliding knot, and secured with 2 or 3 additional throws. Two or 3 TSAs with 1 or 2 threads per anchor are used in most cases. The ultimate failure load of 10 samples of the anchor was tested with porcine scapulae. It was more than 156 N in every case. This technique enables the surgeon to use up to 4 anchors in the unstable shoulder with 1 or 2 sutures per anchor. The anchors are inexpensive. No problems are encountered in case of revision. There is no abrasion in the eyelet of the anchor as with metallic anchors and no synovitis as with some absorbable anchors.

Bone marrow edema of the forefoot after chevron osteotomy--a rare cause of metatarsalgia: a case report.

Treatment options of bone marrow edema syndrome, which is associated with vascular disturbances, are protracted nonoperative treatment or core decompression which still demands several weeks until complete recovery. We obtained excellent results by the use of the vasoactive drug iloprost, a stable prostacyclin analogue, leading to a complete relief of symptoms in cases of bone marrow edema which had initially suggested early avascular necrosis of the second metatarsal head. The bone marrow edema of the second metatarsal bone was thought to be due to altered biomechanics following a distal first metatarsal chevron osteotomy. During the five days of iloprost infusion, the patient reported relief of rest pain. After therapy, the pedobarogram was normalized. The AOFAS forefoot score improved from 44 to 85 points after one month, and to 95 points after three months. At that time, the marrow showed normal signals. Without additional intervention the patient was able to resume normal activities.

Bone marrow edema syndrome in postpartal women: treatment with iloprost.

Bone marrow edema syndrome of the femoral head in pregnant women is a rare disease resulting in disabling coxalgia, beginning in the last 3 months of pregnancy and persisting for several months after parturition. The parenteral administration of the vasoactive drug iloprost constitutes a new approach to the treatment of painful bone marrow edema syndrome of the hip of pregnant women. Six postpartal women (8 hips) with bone marrow edema syndrome of the femoral head were treated with iloprost followed by 3 weeks of partial weight-bearing. Relief from pain, restoration of functional capacity, and normalization of the MRI signal pattern were rapidly achieved, thus avoiding the need for surgical intervention. As the substance is contraindicated in pregnancy, therapy may begin only some days after parturition, with a short discontinuation in breastfeeding.

Outcome of painful bone marrow edema of the femoral head following treatment with parenteral iloprost.

BACKGROUND: Bone marrow edema (BME) is a common cause of hip pain. The aim of the study was to assess the efficacy of the vasoactive drug iloprost in the treatment of BME of femoral head. MATERIALS AND METHODS: We reviewed 27 patients (19 male, 8 female) with BME of the femoral head. Their mean age was 53.7 +/- 10.8 years. All patients were treated with iloprost, a vasoactive drug that dilates arterioles and venules, reduces capillary permeability and suppresses platelet aggregation. The therapy comprised a series of five infusions with 20 to 50 mug iloprost over 6 h on 5 consecutive days each. Weight bearing was reduced for up to 3 weeks, depending on the severity of symptoms. Pain at rest as well as under stress was assessed with a semi quantitative scale from before and 4 months after therapy. MRI investigations were done before and repeated 4 months after therapy. RESULTS: At the clinical follow up of four months after therapy, the pain level at rest had diminished by a mean of 58.3% (P < 0.0001). Pain under stress decreased by a mean of 41.9% (P < 0.0001). On MRI, 20 patients had a significant reduction of BME size or complete normalization and 4 showed no change. Worsening of the MRI pattern was found in 3 patients. CONCLUSION: The authors conclude that the use of parenteral iloprost might be a viable method in the treatment of BME of femoral head.

Two to nineteen years follow-up of arthroscopic meniscal repair using the outside-in technique: a retrospective study.

PURPOSE: To perform a long-term follow-up evaluation of the outside-in technique of arthroscopic meniscal repair. TYPE OF STUDY: Retrospective study. METHODS: Between the years 1986 and 2002, 93 cases of arthroscopic meniscal repair using the outside-in technique have been operated by the senior author (F.L.). Forty-one patients were available for the follow-up evaluation with a mean follow-up of 11.71 years. The International Knee Documentation Committee (IKDC), the modified Lysholm score, the SF-36 (short form 36) health survey score, a visual analogue scale (VAS) for assessment of patients' satisfaction and another VAS for assessment of patients' pain were used retrospectively to evaluate the patients. We also used the Kellgren and Lawrence (K/L) classification of osteoarthritis to evaluate the preoperative X-rays and the X-rays done at the time of the follow-up evaluation. Failure was defined as having a meniscectomy procedure post-operatively. RESULTS: From the 93 patients, 52 could not be retrieved for the follow-up evaluation, while 41 were available for it; 36 patients were clinically successful and 5 were considered as failure. Thirty-six patients were classified as grade "A" in the objective IKDC score, mean modified Lysholm score was 87.29 (SD 16.43), while mean SF-36 score was 85.73 (SD 14.17). The results of the VAS for operation satisfaction ranging from -10 to +10 revealed that the mean of the answers was 8.05 (SD 2.99). The results of the VAS for pain ranging from 0 to 10 revealed that the mean of the patients' pain at the time of the follow-up evaluation was 1.8 (SD 2.42). Twenty out of 24 (only 24 preoperative X-rays were available) were classified as having no osteoarthritis pre-operatively, whereas only 12 out of the 41 patients were classified as having no osteoarthritis (normal) at the time of the follow-up evaluation according to the K/L classification which indicates progression of osteoarthritis. No complications related to the outside-in arthroscopic meniscal repair procedure were reported. CONCLUSION: We conclude that arthroscopic meniscal repair using the outside-in technique is a safe surgical procedure with a good clinical outcome.

Arthroscopic single-stranded semitendinosus tendon- versus PDS-augmentation of reinserted acute femoral anterior cruciate ligament tears: 7 year follow-up study.

This study reviews the long-term results of acute complete femoral tears or combined femoral (2/3 of the ligament diameter) /interstitial tears of the anterior cruciate ligament (ACL) that were reinserted. Out of 27 patients, 11 were treated with reinsertion plus augmentation with single-stranded semitendinosus tendon, 16 patients had a reinsertion and augmentation with a double-stranded PDS-band. Operation was carried out 10 (2-42) days after trauma. A brace was applied for 12 weeks, full weight bearing was allowed after 6 weeks according to our standard rehabilitation protocol. Twenty two patients (81%) could be reevaluated after a mean follow-up time of 7 years 1 month (range 3 years 8 months -11 years 5 months). No statistically significant difference was found between both techniques concerning patient's satisfaction and subjective evaluation of knee function, OAK-scores (semitendinosus-augmentation: 96 point, SD 2.0 PDS-augmentation: 94 points, SD 5.1) and IKDC-scores. Only in the PDS-augmentation group a statistically significant decrease was found in the level of activity in sports (P=0.046). At follow-up, radiological evaluation of the anterior drawer test was performed. In the group of patients who had undergone semitendinosus augmentation (n=9), anterior displacement of the tibia (determined radiologically using the TELOS-device) of 0-2 mm was found in five patients, displacement of 3-5 mm was seen in three cases and displacement of 6-10 mm in one patient (average 2.7 mm). Patients treated with PDS-augmentation (n=13) showed anterior tibial displacement of 0-2 mm in five cases, 3-5 mm in five cases, and 6-10 mm in two knees (average 3.6 mm). One patient of this group underwent ACL-reconstruction 6 years after reinsertion because of recurrent instability. At follow up, flexion was limited to less than 135 degrees in three patients (12.5%). One patient who had undergone semitendinosus augmentation and three patients from the PDS-augmentation group developed a cyclops syndrome and intraarticular adhesions that were treated arthroscopically 6 to 18 month after reinsertion surgery. A tendency towards a higher rate of limitation in range of motion was found for the PDS augmentation group. The reinsertion of a femoral torn ACL plus augmentation with a single strand of semitendinosus tendon or a PDS-band leads to acceptable results, an aggressive rehabilitation protocol may help to decrease the rate of limitation of flexion.

Comparison of debridement versus suture in large rotator cuff tears: long-term study of 64 shoulders.

INTRODUCTION: The goal of this study is to determine whether suturing is superior to non-closure in terms of the subjective long-term outcome in large rotator cuff tears. MATERIALS AND METHODS: A total of 64 shoulders with rotator cuff tears of at least 3 cm diameter and followed up for a mean period of 5 years and 8 months were retrospectively examined. The patients' medical history, clinical findings, radiographs and Constant scores were studied. Patients whose tears had been closed with an open suture (n=33) were compared with those whose tears had not been closed (n=31). RESULTS: Neither the comparison between open suturing and debridement nor that between open and arthroscopic debridement reveal a significant difference with regard to the overall Constant score or the individual parameters. CONCLUSION: These results suggest that in the long-term, suturing of large rotator cuff tears is not superior to debridement.