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1.

Prion disease is accelerated in mice lacking stress-induced heat shock protein 70 (HSP70).

Mays, Charles E; Armijo, Enrique; Morales, Rodrigo; Kramm, Carlos; Flores, Andrea; Tiwari, Anjana; Bian, Jifeng; Telling, Glenn C; Pandita, Tej K; Hunt, Clayton R; Soto, Claudio.

J Biol Chem ; 294(37): 13619-13628, 2019 09 13.

Artículo en Inglés | MEDLINE | ID: mdl-31320473

2.

A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alleles.

Mercer, Robert C C; Daude, Nathalie; Dorosh, Lyudmyla; Fu, Ze-Lin; Mays, Charles E; Gapeshina, Hristina; Wohlgemuth, Serene L; Acevedo-Morantes, Claudia Y; Yang, Jing; Cashman, Neil R; Coulthart, Michael B; Pearson, Dawn M; Joseph, Jeffrey T; Wille, Holger; Safar, Jiri G; Jansen, Gerard H; Stepanova, Maria; Sykes, Brian D; Westaway, David.

PLoS Pathog ; 14(1): e1006826, 2018 01.

Artículo en Inglés | MEDLINE | ID: mdl-29338055

3.

Modeling amyloid beta and tau pathology in human cerebral organoids.

Gonzalez, Cesar; Armijo, Enrique; Bravo-Alegria, Javiera; Becerra-Calixto, Andrea; Mays, Charles E; Soto, Claudio.

Mol Psychiatry ; 23(12): 2363-2374, 2018 12.

Artículo en Inglés | MEDLINE | ID: mdl-30171212

4.

Inhibition of protein misfolding and aggregation by natural phenolic compounds.

Dhouafli, Zohra; Cuanalo-Contreras, Karina; Hayouni, El Akrem; Mays, Charles E; Soto, Claudio; Moreno-Gonzalez, Ines.

Cell Mol Life Sci ; 75(19): 3521-3538, 2018 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-30030591

5.

Prion Infectivity Plateaus and Conversion to Symptomatic Disease Originate from Falling Precursor Levels and Increased Levels of Oligomeric PrPSc Species.

Mays, Charles E; van der Merwe, Jacques; Kim, Chae; Haldiman, Tracy; McKenzie, Debbie; Safar, Jiri G; Westaway, David.

J Virol ; 89(24): 12418-26, 2015 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-26423957

6.

Infectious prions accumulate to high levels in non proliferative C2C12 myotubes.

Herbst, Allen; Banser, Pamela; Velasquez, Camilo Duque; Mays, Charles E; Sim, Valerie L; Westaway, David; Aiken, Judd M; McKenzie, Debbie.

PLoS Pathog ; 9(11): e1003755, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-24244171

7.

Down-regulation of Shadoo in prion infections traces a pre-clinical event inversely related to PrP(Sc) accumulation.

Westaway, David; Genovesi, Sacha; Daude, Nathalie; Brown, Rebecca; Lau, Agnes; Lee, Inyoul; Mays, Charles E; Coomaraswamy, Janaky; Canine, Brenda; Pitstick, Rose; Herbst, Allen; Yang, Jing; Ko, Kerry W S; Schmitt-Ulms, Gerold; Dearmond, Stephen J; McKenzie, Debbie; Hood, Leroy; Carlson, George A.

PLoS Pathog ; 7(11): e1002391, 2011 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-22114562

8.

RGG repeats of PrP-like Shadoo protein bind nucleic acids.

Lau, Agnes; Mays, Charles E; Genovesi, Sacha; Westaway, David.

Biochemistry ; 51(45): 9029-31, 2012 Nov 13.

Artículo en Inglés | MEDLINE | ID: mdl-23121093

9.

Endoproteolysis of cellular prion protein by plasmin hinders propagation of prions.

Mays, Charles E; Trinh, Trang H T; Telling, Glenn; Kang, Hae-Eun; Ryou, Chongsuk.

Front Mol Neurosci ; 15: 990136, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-36117913

10.

Plasminogen stimulates propagation of protease-resistant prion protein in vitro.

Mays, Charles E; Ryou, Chongsuk.

FASEB J ; 24(12): 5102-12, 2010 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-20732953

11.

Enhancement of protein misfolding cyclic amplification by using concentrated cellular prion protein source.

Mays, Charles E; Titlow, William; Seward, Tanya; Telling, Glenn C; Ryou, Chongsuk.

Biochem Biophys Res Commun ; 388(2): 306-10, 2009 Oct 16.

Artículo en Inglés | MEDLINE | ID: mdl-19664595

12.

Changes in gene expression of kringle domain-containing proteins in murine brains and neuroblastoma cells infected by prions.

Kim, Younghwan; Song, Jihyun; Mays, Charles E; Titlow, William; Yoon, Donghoon; Ryou, Chongsuk.

Mol Cell Biochem ; 328(1-2): 177-82, 2009 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-19322640

13.

Application of PMCA to screen for prion infection in a human cell line used to produce biological therapeutics.

Lyon, Adam; Mays, Charles E; Borriello, Frank; Telling, Glenn C; Soto, Claudio; Pritzkow, Sandra.

Sci Rep ; 9(1): 4847, 2019 03 19.

Artículo en Inglés | MEDLINE | ID: mdl-30890734

14.

Proteasomal Inhibition Redirects the PrP-Like Shadoo Protein to the Nucleus.

Kang, Sang-Gyun; Mays, Charles E; Daude, Nathalie; Yang, Jing; Kar, Satyabrata; Westaway, David.

Mol Neurobiol ; 56(11): 7888-7904, 2019 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-31129810

15.

CRBL cells: establishment, characterization and susceptibility to prion infection.

Mays, Charles E; Kang, Hae-Eun; Kim, Younghwan; Shim, Sung Han; Bang, Ji-Eun; Woo, Hee-Jong; Cho, Youl-Hee; Kim, Jae-Beom; Ryou, Chongsuk.

Brain Res ; 1208: 170-80, 2008 May 07.

Artículo en Inglés | MEDLINE | ID: mdl-18395703

16.

Prion propagation in vitro: are we there yet?

Ryou, Chongsuk; Mays, Charles E.

Int J Med Sci ; 5(6): 347-53, 2008.

Artículo en Inglés | MEDLINE | ID: mdl-19015743

17.

The stress of prion disease.

Mays, Charles E; Soto, Claudio.

Brain Res ; 1648(Pt B): 553-560, 2016 10 01.

Artículo en Inglés | MEDLINE | ID: mdl-27060771

18.

Inhibition of the FKBP family of peptidyl prolyl isomerases induces abortive translocation and degradation of the cellular prion protein.

Stocki, Pawel; Sawicki, Maxime; Mays, Charles E; Hong, Seo Jung; Chapman, Daniel C; Westaway, David; Williams, David B.

Mol Biol Cell ; 27(5): 757-67, 2016 Mar 01.

Artículo en Inglés | MEDLINE | ID: mdl-26764098

19.

Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation.

Lau, Agnes; McDonald, Alex; Daude, Nathalie; Mays, Charles E; Walter, Eric D; Aglietti, Robin; Mercer, Robert C C; Wohlgemuth, Serene; van der Merwe, Jacques; Yang, Jing; Gapeshina, Hristina; Kim, Chae; Grams, Jennifer; Shi, Beipei; Wille, Holger; Balachandran, Aru; Schmitt-Ulms, Gerold; Safar, Jiri G; Millhauser, Glenn L; Westaway, David.

EMBO Mol Med ; 7(3): 339-56, 2015 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-25661904

20.

Endoproteolytic processing of the mammalian prion glycoprotein family.

Mays, Charles E; Coomaraswamy, Janaky; Watts, Joel C; Yang, Jing; Ko, Kerry W S; Strome, Bob; Mercer, Robert C C; Wohlgemuth, Serene L; Schmitt-Ulms, Gerold; Westaway, David.

FEBS J ; 281(3): 862-76, 2014 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-24286250

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