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1.

Biology of factor XI.

Moellmer, Samantha A; Puy, Cristina; McCarty, Owen J T.

Blood ; 143(15): 1445-1454, 2024 Apr 11.

Artículo en Inglés | MEDLINE | ID: mdl-37874916

2.

Factor XI Inhibition for the Prevention of Catheter-Associated Thrombosis in Patients With Cancer Undergoing Central Line Placement: A Phase 2 Clinical Trial.

Pfeffer, Michael A; Kohs, Tia C L; Vu, Helen H; Jordan, Kelley R; Wang, Jenny Si Han; Lorentz, Christina U; Tucker, Erik I; Puy, Cristina; Olson, Sven R; DeLoughery, Thomas G; Hinds, Monica T; Keshari, Ravi S; Gailani, David; Lupu, Florea; McCarty, Owen J T; Shatzel, Joseph J.

Arterioscler Thromb Vasc Biol ; 44(1): 290-299, 2024 01.

Artículo en Inglés | MEDLINE | ID: mdl-37970718

3.

Factor XI as a therapeutic target in neuroinflammatory disease.

Taskin, Berk; Kohs, Tia C L; Shatzel, Joseph J; Puy, Cristina; McCarty, Owen J T.

Curr Opin Hematol ; 31(1): 32-38, 2024 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-37694771

4.

Cytoprotective E-WE thrombin reduces disease severity in a murine model of relapsing-remitting multiple sclerosis.

Verbout, Norah G; Su, Weiping; Pham, Peter; Jordan, Kelley R; Kohs, Tia C L; Tucker, Erik I; McCarty, Owen J T; Sherman, Larry S.

Am J Physiol Cell Physiol ; 326(1): C40-C49, 2024 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-37955120

5.

Comparison of bleeding and thrombotic outcomes in veno-venous extracorporeal membrane oxygenation: Heparin versus bivalirudin.

Kartika, Thomas; Mathews, Rick; Migneco, Gina; Bundy, Taylor; Kaempf, Andy J; Pfeffer, Michael; DeLoughery, Thomas G; Moore, Kerry; Beardshear, Rachel; Oetken, Heath J; Case, Jonathan; Hinds, Monica T; McCarty, Owen J T; Shatzel, Joseph J; Zonies, David; Zakhary, Bishoy.

Eur J Haematol ; 112(4): 566-576, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38088062

6.

Predictors of thrombosis during VV ECMO: an analysis of 9809 patients from the ELSO registry.

Kohs, Tia C L; Weeder, Benjamin R; Chobrutskiy, Boris I; Kartika, Thomas; Moore, Kerry K; McCarty, Owen J T; Zonies, David; Zakhary, Bishoy; Shatzel, Joseph J.

J Thromb Thrombolysis ; 57(3): 345-351, 2024 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-38095743

7.

Skeletal muscle myosin promotes coagulation by binding factor XI via its A3 domain and enhancing thrombin-induced factor XI activation.

Morla, Shravan; Deguchi, Hiroshi; Zilberman-Rudenko, Jevgenia; Gruber, András; McCarty, Owen J T; Srivastava, Priyanka; Gailani, David; Griffin, John H.

J Biol Chem ; 298(2): 101567, 2022 02.

Artículo en Inglés | MEDLINE | ID: mdl-35007530

8.

Targeting the Contact Pathway of Coagulation for the Prevention and Management of Medical Device-Associated Thrombosis.

Goel, Abhishek; Tathireddy, Harsha; Wang, Si-Han; Vu, Helen H; Puy, Cristina; Hinds, Monica T; Zonies, David; McCarty, Owen J T; Shatzel, Joseph J.

Semin Thromb Hemost ; 2023 Apr 12.

Artículo en Inglés | MEDLINE | ID: mdl-37044117

9.

Substrates, Cofactors, and Cellular Targets of Coagulation Factor XIa.

Lira, André L; Kohs, Tia C L; Moellmer, Samantha A; Shatzel, Joseph J; McCarty, Owen J T; Puy, Cristina.

Semin Thromb Hemost ; 2023 Mar 20.

Artículo en Inglés | MEDLINE | ID: mdl-36940715

10.

Aspirin and antiplatelet treatments in cancer.

Tao, Derrick L; Tassi Yunga, Samuel; Williams, Craig D; McCarty, Owen J T.

Blood ; 137(23): 3201-3211, 2021 06 10.

Artículo en Inglés | MEDLINE | ID: mdl-33940597

11.

The contact activation inhibitor AB023 in heparin-free hemodialysis: results of a randomized phase 2 clinical trial.

Lorentz, Christina U; Tucker, Erik I; Verbout, Norah G; Shatzel, Joseph J; Olson, Sven R; Markway, Brandon D; Wallisch, Michael; Ralle, Martina; Hinds, Monica T; McCarty, Owen J T; Gailani, David; Weitz, Jeffrey I; Gruber, András.

Blood ; 138(22): 2173-2184, 2021 12 02.

Artículo en Inglés | MEDLINE | ID: mdl-34086880

12.

Factor XII plays a pathogenic role in organ failure and death in baboons challenged with Staphylococcus aureus.

Silasi, Robert; Keshari, Ravi S; Regmi, Girija; Lupu, Cristina; Georgescu, Constantin; Simmons, Joe H; Wallisch, Michael; Kohs, Tia C L; Shatzel, Joseph J; Olson, Sven R; Lorentz, Christina U; Puy, Cristina; Tucker, Erik I; Gailani, David; Strickland, Sidney; Gruber, András; McCarty, Owen J T; Lupu, Florea.

Blood ; 138(2): 178-189, 2021 07 15.

Artículo en Inglés | MEDLINE | ID: mdl-33598692

13.

Estrogen-based hormonal therapy and the risk of thrombosis in COVID-19 patients.

LaVasseur, Corinne; Mathews, Rick; Wang, Jenny S H; Martens, Kylee; McMurry, Hannah Stowe; Peress, Shira; Sabile, Jean; Kartika, Thomas; Oleson, Ileisa; Lo, Jamie O; DeLoughery, Thomas G; McCarty, Owen J T; Shatzel, Joseph J.

Eur J Haematol ; 111(5): 678-686, 2023 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-37519103

14.

Cross-Talk between the Complement Pathway and the Contact Activation System of Coagulation: Activated Factor XI Neutralizes Complement Factor H.

Puy, Cristina; Pang, Jiaqing; Reitsma, Stéphanie E; Lorentz, Christina U; Tucker, Erik I; Gailani, David; Gruber, András; Lupu, Florea; McCarty, Owen J T.

J Immunol ; 206(8): 1784-1792, 2021 04 15.

Artículo en Inglés | MEDLINE | ID: mdl-33811105

15.

Pharmacological targeting of coagulation factor XI attenuates experimental autoimmune encephalomyelitis in mice.

Kohs, Tia C L; Fallon, Meghan E; Oseas, Ethan C; Healy, Laura D; Tucker, Erik I; Gailani, David; McCarty, Owen J T; Vandenbark, Arthur A; Offner, Halina; Verbout, Norah G.

Metab Brain Dis ; 38(7): 2383-2391, 2023 10.

Artículo en Inglés | MEDLINE | ID: mdl-37341855

16.

Platelets and tyrosine kinase inhibitors: clinical features, mechanisms of action, and effects on physiology.

Zheng, Tony J; Parra-Izquierdo, Iván; Reitsma, Stéphanie E; Heinrich, Michael C; Larson, Mark K; Shatzel, Joseph J; Aslan, Joseph E; McCarty, Owen J T.

Am J Physiol Cell Physiol ; 323(4): C1231-C1250, 2022 Oct 01.

Artículo en Inglés | MEDLINE | ID: mdl-35938677

17.

Chronic edible dosing of Δ9-tetrahydrocannabinol (THC) in nonhuman primates reduces systemic platelet activity and function.

Reitsma, Stéphanie E; Lakshmanan, Hari Hara Sudhan; Johnson, Jennifer; Pang, Jiaqing; Parra-Izquierdo, Iván; Melrose, Alex R; Choi, Jaewoo; Anderson, Deirdre E J; Hinds, Monica T; Stevens, Jan Frederik; Aslan, Joseph E; McCarty, Owen J T; Lo, Jamie O.

Am J Physiol Cell Physiol ; 322(3): C370-C381, 2022 03 01.

Artículo en Inglés | MEDLINE | ID: mdl-35080922

18.

Phosphoproteomic quantitation and causal analysis reveal pathways in GPVI/ITAM-mediated platelet activation programs.

Babur, Özgün; Melrose, Alexander R; Cunliffe, Jennifer M; Klimek, John; Pang, Jiaqing; Sepp, Anna-Liisa I; Zilberman-Rudenko, Jevgenia; Tassi Yunga, Samuel; Zheng, Tony; Parra-Izquierdo, Iván; Minnier, Jessica; McCarty, Owen J T; Demir, Emek; Reddy, Ashok P; Wilmarth, Phillip A; David, Larry L; Aslan, Joseph E.

Blood ; 136(20): 2346-2358, 2020 11 12.

Artículo en Inglés | MEDLINE | ID: mdl-32640021

19.

The protein C activator AB002 rapidly interrupts thrombus development in baboons.

Tucker, Erik I; Verbout, Norah G; Markway, Brandon D; Wallisch, Michael; Lorentz, Christina U; Hinds, Monica T; Shatzel, Joseph J; Pelc, Leslie A; Wood, David C; McCarty, Owen J T; Di Cera, Enrico; Gruber, András.

Blood ; 135(9): 689-699, 2020 02 27.

Artículo en Inglés | MEDLINE | ID: mdl-31977000

20.

The efficacy and safety of thrombopoietin receptor agonists in patients with chronic liver disease undergoing elective procedures: a systematic review and meta-analysis.

Lindquist, Ingrid; Olson, Sven R; Li, Ang; Al-Samkari, Hanny; Jou, Janice H; McCarty, Owen J T; Shatzel, Joseph J.

Platelets ; 33(1): 66-72, 2022 Jan 02.

Artículo en Inglés | MEDLINE | ID: mdl-33459573

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