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1.

Fast and sensitive dynamic oxygen-enhanced MRI with a cycling gas challenge and independent component analysis.

Moosvi, Firas; Baker, Jennifer H E; Yung, Andrew; Kozlowski, Piotr; Minchinton, Andrew I; Reinsberg, Stefan A.

Magn Reson Med ; 81(4): 2514-2525, 2019 04.

Artículo en Inglés | MEDLINE | ID: mdl-30368892

2.

The differential effects of metronomic gemcitabine and antiangiogenic treatment in patient-derived xenografts of pancreatic cancer: treatment effects on metabolism, vascular function, cell proliferation, and tumor growth.

Yapp, Donald T; Wong, May Q; Kyle, Alastair H; Valdez, Shannon M; Tso, Jenny; Yung, Andrew; Kozlowski, Piotr; Owen, David A; Buczkowski, Andrzej K; Chung, Stephen W; Scudamore, Charles H; Minchinton, Andrew I; Ng, Sylvia S W.

Angiogenesis ; 19(2): 229-44, 2016 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-26961182

3.

Drug penetration in solid tumours.

Minchinton, Andrew I; Tannock, Ian F.

Nat Rev Cancer ; 6(8): 583-92, 2006 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-16862189

4.

Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling.

Chang, Linda; Noseda, Michela; Higginson, Michelle; Ly, Michelle; Patenaude, Alexandre; Fuller, Megan; Kyle, Alastair H; Minchinton, Andrew I; Puri, Mira C; Dumont, Daniel J; Karsan, Aly.

Proc Natl Acad Sci U S A ; 109(18): 6993-8, 2012 May 01.

Artículo en Inglés | MEDLINE | ID: mdl-22509029

5.

DNA-PK inhibitor AZD7648 is a more portent radiosensitizer than PARP inhibitor Olaparib in BRCA1/2 deficient tumors.

Wang, Taixiang; Kyle, Alastair H; Baker, Jennifer H E; Liu, Nannan A; Banáth, Judit P; Teymori, Sevin; Minchinton, Andrew I.

DNA Repair (Amst) ; 139: 103689, 2024 May 06.

Artículo en Inglés | MEDLINE | ID: mdl-38749239

6.

Radiation and chemo-sensitizing effects of DNA-PK inhibitors are proportional in tumors and normal tissues.

Baker, Jennifer H E; Kyle, Alastair H; Liu, Nannan Anam; Wang, Taixiang; Liu, Xinhe; Teymori, Sevin; Banáth, Judit P; Minchinton, Andrew I.

Mol Cancer Ther ; 2024 May 23.

Artículo en Inglés | MEDLINE | ID: mdl-38781104

7.

Detection of FLASH-radiotherapy tissue sparing in a 3D-spheroid model using DNA damage response markers.

Kyle, Alastair H; Karan, Tania; Baker, Jennifer H E; Püspöky Banáth, Judit; Wang, Taixiang; Liu, Anam; Mendez, Claudia; Peter Petric, M; Duzenli, Cheryl; Minchinton, Andrew I.

Radiother Oncol ; 196: 110326, 2024 May 10.

Artículo en Inglés | MEDLINE | ID: mdl-38735536

8.

DNA-PK inhibition extends the therapeutic effects of Top2 poisoning to non-proliferating cells, increasing activity at a cost.

Wang, Taixiang; Kyle, Alastair H; Baker, Jennifer H E; Liu, Nannan A; Banáth, Judit P; Minchinton, Andrew I.

Sci Rep ; 13(1): 12429, 2023 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-37528151

9.

The combination of gefitinib and RAD001 inhibits growth of HER2 overexpressing breast cancer cells and tumors irrespective of trastuzumab sensitivity.

Dragowska, Wieslawa H; Weppler, Sherry A; Qadir, Mohammed A; Wong, Ling Yan; Franssen, Yannick; Baker, Jennifer H E; Kapanen, Anita I; Kierkels, Guido J J; Masin, Dana; Minchinton, Andrew I; Gelmon, Karen A; Bally, Marcel B.

BMC Cancer ; 11: 420, 2011 Oct 01.

Artículo en Inglés | MEDLINE | ID: mdl-21961653

10.

Vascularization predicts overall survival and risk of transformation in follicular lymphoma.

Farinha, Pedro; Kyle, Alastair H; Minchinton, Andrew I; Connors, Joseph M; Karsan, Aly; Gascoyne, Randy D.

Haematologica ; 95(12): 2157-60, 2010 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-20713461

11.

Direct visualization of heterogeneous extravascular distribution of trastuzumab in human epidermal growth factor receptor type 2 overexpressing xenografts.

Baker, Jennifer H E; Lindquist, Kirstin E; Huxham, Lynsey A; Kyle, Alastair H; Sy, Jonathan T; Minchinton, Andrew I.

Clin Cancer Res ; 14(7): 2171-9, 2008 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-18381959

12.

Irinophore C, a novel nanoformulation of irinotecan, alters tumor vascular function and enhances the distribution of 5-fluorouracil and doxorubicin.

Baker, Jennifer H E; Lam, Jeffrey; Kyle, Alaistair H; Sy, Jonathan; Oliver, Thomas; Co, Steven J; Dragowska, Wieslawa H; Ramsay, Euan; Anantha, Malathi; Ruth, Thomas J; Adam, Michael J; Yung, Andrew; Kozlowski, Piotr; Minchinton, Andrew I; Ng, Sylvia S W; Bally, Marcel B; Yapp, Donald T T.

Clin Cancer Res ; 14(22): 7260-71, 2008 Nov 15.

Artículo en Inglés | MEDLINE | ID: mdl-19010842

13.

Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of integrin-linked kinase (ILK).

Edwards, Lincoln A; Woo, Janet; Huxham, Lynsey A; Verreault, Maite; Dragowska, Wieslawa H; Chiu, Gigi; Rajput, Ashish; Kyle, Alastair H; Kalra, Jessica; Yapp, Donald; Yan, Hong; Minchinton, Andrew I; Huntsman, David; Daynard, Tim; Waterhouse, Dawn N; Thiessen, B; Dedhar, Shoukat; Bally, Marcel B.

Mol Cancer Ther ; 7(1): 59-70, 2008 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-18202010

14.

Targeting Hypoxia-Induced Carbonic Anhydrase IX Enhances Immune-Checkpoint Blockade Locally and Systemically.

Chafe, Shawn C; McDonald, Paul C; Saberi, Saeed; Nemirovsky, Oksana; Venkateswaran, Geetha; Burugu, Samantha; Gao, Dongxia; Delaidelli, Alberto; Kyle, Alastair H; Baker, Jennifer H E; Gillespie, Jordan A; Bashashati, Ali; Minchinton, Andrew I; Zhou, Youwen; Shah, Sohrab P; Dedhar, Shoukat.

Cancer Immunol Res ; 7(7): 1064-1078, 2019 07.

Artículo en Inglés | MEDLINE | ID: mdl-31088846

15.

Endothelial Sash1 Is Required for Lung Maturation through Nitric Oxide Signaling.

Coulombe, Patrick; Paliouras, Grigorios N; Clayton, Ashley; Hussainkhel, Angela; Fuller, Megan; Jovanovic, Vida; Dauphinee, Shauna; Umlandt, Patricia; Xiang, Ping; Kyle, Alistair H; Minchinton, Andrew I; Humphries, R Keith; Hoodless, Pamela A; Parker, Jeremy D K; Wright, Joanne L; Karsan, Aly.

Cell Rep ; 27(6): 1769-1780.e4, 2019 05 07.

Artículo en Inglés | MEDLINE | ID: mdl-31067462

16.

Limited tissue penetration of taxanes: a mechanism for resistance in solid tumors.

Kyle, Alastair H; Huxham, Lynsey A; Yeoman, Devon M; Minchinton, Andrew I.

Clin Cancer Res ; 13(9): 2804-10, 2007 May 01.

Artículo en Inglés | MEDLINE | ID: mdl-17473214

17.

The impact of complement activation on tumor oxygenation during photodynamic therapy.

Cecic, Ivana; Minchinton, Andrew I; Korbelik, Mladen.

Photochem Photobiol ; 83(5): 1049-55, 2007.

Artículo en Inglés | MEDLINE | ID: mdl-17880499

18.

Tirapazamine causes vascular dysfunction in HCT-116 tumour xenografts.

Huxham, Lynsey A; Kyle, Alastair H; Baker, Jennifer H E; McNicol, Krista L; Minchinton, Andrew I.

Radiother Oncol ; 78(2): 138-45, 2006 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-16455148

19.

Tumor distribution of bromodeoxyuridine-labeled cells is strongly dose dependent.

Kyle, Alastair H; Huxham, Lynsey A; Baker, Jennifer H E; Burston, Helen E; Minchinton, Andrew I.

Cancer Res ; 63(18): 5707-11, 2003 Sep 15.

Artículo en Inglés | MEDLINE | ID: mdl-14522888

20.

Microregional effects of gemcitabine in HCT-116 xenografts.

Huxham, Lynsey A; Kyle, Alastair H; Baker, Jennifer H E; Nykilchuk, Lani K; Minchinton, Andrew I.

Cancer Res ; 64(18): 6537-41, 2004 Sep 15.

Artículo en Inglés | MEDLINE | ID: mdl-15374965

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